WO2006050032A3 - System and method for analyte sampling and analysis with hydrogel - Google Patents

System and method for analyte sampling and analysis with hydrogel Download PDF

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Publication number
WO2006050032A3
WO2006050032A3 PCT/US2005/038785 US2005038785W WO2006050032A3 WO 2006050032 A3 WO2006050032 A3 WO 2006050032A3 US 2005038785 W US2005038785 W US 2005038785W WO 2006050032 A3 WO2006050032 A3 WO 2006050032A3
Authority
WO
WIPO (PCT)
Prior art keywords
analyte
biological membrane
electrode assembly
medium
based hydrogel
Prior art date
Application number
PCT/US2005/038785
Other languages
French (fr)
Other versions
WO2006050032A2 (en
WO2006050032A9 (en
Inventor
Han Chuang
Shikha P Barman
Original Assignee
Sontra Medical Corp
Han Chuang
Shikha P Barman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/223,971 external-priority patent/US8224414B2/en
Application filed by Sontra Medical Corp, Han Chuang, Shikha P Barman filed Critical Sontra Medical Corp
Priority to CA2584699A priority Critical patent/CA2584699C/en
Priority to JP2007539116A priority patent/JP5502279B2/en
Priority to AU2005302584A priority patent/AU2005302584B2/en
Priority to EP05824881A priority patent/EP1819283A4/en
Priority to BRPI0517255-1A priority patent/BRPI0517255A/en
Priority to NZ554624A priority patent/NZ554624A/en
Publication of WO2006050032A2 publication Critical patent/WO2006050032A2/en
Publication of WO2006050032A3 publication Critical patent/WO2006050032A3/en
Publication of WO2006050032A9 publication Critical patent/WO2006050032A9/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/681—Wristwatch-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150083—Means for enhancing collection by vibration, e.g. ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150358—Strips for collecting blood, e.g. absorbent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15134—Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B2010/0003—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements including means for analysis by an unskilled person

Abstract

The invention relates to a transdermal analyte monitoring system comprising a medium adapted to interface with a biological membrane and to receive an analyte from the biological membrane and an electrode assembly comprising a plurality of electrodes, wherein the medium is adapted to react continuously with the analyte, an electrical signal is detected by the electrode assembly, and the electrical signal correlates to an analyte value. The analyte value may be the flux of the analyte through the biological membrane or the concentration of the analyte in a body fluid of a subject. The medium may comprise a vinyl acetate based hydrogel, an agarose based hydrogel, or a polyethylene glycol diacrylate (PEG-DA) based hydrogel, for example. The surface region of the electrode may comprise pure platinum. The system may include an interference filter located between the biological membrane and the electrode assembly for reducing interference in the system. The system may comprise a processor programmed to implement an error correction method that corrects for sensor drift.
PCT/US2005/038785 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with hydrogel WO2006050032A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA2584699A CA2584699C (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with hydrogel
JP2007539116A JP5502279B2 (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis using hydrogels
AU2005302584A AU2005302584B2 (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with hydrogel
EP05824881A EP1819283A4 (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with hydrogel
BRPI0517255-1A BRPI0517255A (en) 2004-10-28 2005-10-27 hydrogel analyte sampling and analysis system and method
NZ554624A NZ554624A (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with hydrogel

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US97496304A 2004-10-28 2004-10-28
US10/974,963 2004-10-28
US20133405A 2005-08-11 2005-08-11
US11/201,334 2005-08-11
US11/223,971 US8224414B2 (en) 2004-10-28 2005-09-13 System and method for analyte sampling and analysis with hydrogel
US11/223,960 US20060094945A1 (en) 2004-10-28 2005-09-13 System and method for analyte sampling and analysis
US11/223,971 2005-09-13
US11/223,957 US20060094944A1 (en) 2004-10-28 2005-09-13 System and method for analyte sampling and analysis with error correction

Publications (3)

Publication Number Publication Date
WO2006050032A2 WO2006050032A2 (en) 2006-05-11
WO2006050032A3 true WO2006050032A3 (en) 2006-09-08
WO2006050032A9 WO2006050032A9 (en) 2006-11-02

Family

ID=38441686

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2005/038785 WO2006050032A2 (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with hydrogel
PCT/US2005/038786 WO2006050033A2 (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis
PCT/US2005/038784 WO2006050031A2 (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with error correction

Family Applications After (2)

Application Number Title Priority Date Filing Date
PCT/US2005/038786 WO2006050033A2 (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis
PCT/US2005/038784 WO2006050031A2 (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with error correction

Country Status (4)

Country Link
EP (1) EP1819283A4 (en)
AU (1) AU2005302584B2 (en)
CA (1) CA2584699C (en)
WO (3) WO2006050032A2 (en)

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US20090137888A9 (en) * 2001-04-27 2009-05-28 Berman Herbert L System for monitoring of patients
CN101454667B (en) 2005-12-27 2013-04-24 拜尔保健有限公司 Electrochemical sensor system using a substrate with at least one aperature and method of making the same
EP1991113B1 (en) * 2006-02-27 2014-08-20 Edwards Lifesciences Corporation Flux limiting membrane for intravenous amperometric biosensor
US8812071B2 (en) 2007-03-07 2014-08-19 Echo Therapeutics, Inc. Transdermal analyte monitoring systems and methods for analyte detection
WO2010013808A1 (en) * 2008-07-31 2010-02-04 シスメックス株式会社 Method for assaying in vivo component, data processing method for assaying in vivo component and apparatus and collection member for assaying in vivo component
EP2341953B1 (en) 2008-09-04 2018-11-21 The General Hospital Corporation Hydrogels for vocal cord and soft tissue augmentation and repair
WO2010061386A2 (en) * 2008-11-25 2010-06-03 B.G. Negev Technologies And Applications Ltd. Pharmaceutical composition and system for permeabilizing fetal membranes
EP2208458A1 (en) * 2009-01-14 2010-07-21 Roche Diagnostics GmbH Medical monitoring network
WO2012018486A2 (en) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
EP2408369A1 (en) 2009-03-02 2012-01-25 Seventh Sense Biosystems, Inc. Devices and methods for the analysis of an extractable medium
WO2011109730A2 (en) 2010-03-04 2011-09-09 The General Hospital Corporation Methods and systems of matching voice deficits with a tunable mucosal implant to restore and enhance individualized human sound and voice production
US20120006100A1 (en) 2010-07-06 2012-01-12 Medtronic Minimed, Inc. Method and/or system for determining blood glucose reference sample times
WO2012021801A2 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
JP2014516644A (en) 2011-04-29 2014-07-17 セブンス センス バイオシステムズ，インコーポレーテッド Devices and methods for collection and / or manipulation of blood spots or other body fluids
KR102013466B1 (en) 2011-04-29 2019-08-22 세븐쓰 센스 바이오시스템즈, 인크. Delivering and/or receiving fluids
EP2701598A1 (en) 2011-04-29 2014-03-05 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
US9968284B2 (en) 2011-12-02 2018-05-15 Clinitech, Llc Anti-interferent barrier layers for non-invasive transdermal sampling and analysis device
KR20170099738A (en) 2016-02-23 2017-09-01 노을 주식회사 Contact-type staining patch and manufacturing method thereof
US10371610B2 (en) 2016-02-23 2019-08-06 Noul Co., Ltd. Contact-type patch, staining method using the same, and manufacturing method thereof
US11375931B2 (en) 2019-08-08 2022-07-05 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating an electrochemical bioassay

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Also Published As

Publication number Publication date
AU2005302584B2 (en) 2011-08-11
WO2006050032A2 (en) 2006-05-11
CA2584699A1 (en) 2006-05-11
CA2584699C (en) 2015-12-08
WO2006050031A3 (en) 2007-05-18
WO2006050033A9 (en) 2007-02-01
WO2006050033B1 (en) 2006-12-14
WO2006050031A9 (en) 2006-06-15
WO2006050031A2 (en) 2006-05-11
WO2006050033A2 (en) 2006-05-11
AU2005302584A1 (en) 2006-05-11
EP1819283A2 (en) 2007-08-22
EP1819283A4 (en) 2011-08-10
WO2006050033A3 (en) 2006-11-02
WO2006050032A9 (en) 2006-11-02

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