WO2006036969A3 - Formation of barrier layer - Google Patents

Formation of barrier layer Download PDF

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Publication number
WO2006036969A3
WO2006036969A3 PCT/US2005/034614 US2005034614W WO2006036969A3 WO 2006036969 A3 WO2006036969 A3 WO 2006036969A3 US 2005034614 W US2005034614 W US 2005034614W WO 2006036969 A3 WO2006036969 A3 WO 2006036969A3
Authority
WO
WIPO (PCT)
Prior art keywords
barrier layer
medical device
naturally occurring
oil
addition
Prior art date
Application number
PCT/US2005/034614
Other languages
French (fr)
Other versions
WO2006036969A2 (en
Inventor
Joseph Ferraro
Lisa Rogers
Paul Martakos
Theodore Karwoski
Steve A Herweck
Keith Faucher
Philip Mcnamara
William Quigley
Mark D Avella
Rick Chenel
Original Assignee
Atrium Medical Corp
Joseph Ferraro
Lisa Rogers
Paul Martakos
Theodore Karwoski
Steve A Herweck
Keith Faucher
Philip Mcnamara
William Quigley
Mark D Avella
Rick Chenel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Atrium Medical Corp, Joseph Ferraro, Lisa Rogers, Paul Martakos, Theodore Karwoski, Steve A Herweck, Keith Faucher, Philip Mcnamara, William Quigley, Mark D Avella, Rick Chenel filed Critical Atrium Medical Corp
Publication of WO2006036969A2 publication Critical patent/WO2006036969A2/en
Publication of WO2006036969A3 publication Critical patent/WO2006036969A3/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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    • A61F13/00Bandages or dressings; Absorbent pads
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    • A61F13/023Adhesive plasters or dressings wound covering film layers without a fluid handling layer
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    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
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    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
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    • A61L2300/602Type of release, e.g. controlled, sustained, slow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D3/00Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
    • B05D3/06Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to radiation
    • B05D3/061Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to radiation using U.V.
    • B05D3/065After-treatment
    • B05D3/067Curing or cross-linking the coating

Abstract

A barrier layer and corresponding method of making provide anti-inflammatory and anti-adhesion functionality for a medical device implantable in a patient. The barrier layer can be combined with a medical device structure to provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The barrier layer is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross linked gel derived from at least one fatty acid compound. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent.
PCT/US2005/034614 2004-09-28 2005-09-28 Formation of barrier layer WO2006036969A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61380804P 2004-09-28 2004-09-28
US60/613,808 2004-09-28

Publications (2)

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WO2006036969A2 WO2006036969A2 (en) 2006-04-06
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