WO2006034232A3 - Diagnostic marker - Google Patents

Diagnostic marker Download PDF

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Publication number
WO2006034232A3
WO2006034232A3 PCT/US2005/033548 US2005033548W WO2006034232A3 WO 2006034232 A3 WO2006034232 A3 WO 2006034232A3 US 2005033548 W US2005033548 W US 2005033548W WO 2006034232 A3 WO2006034232 A3 WO 2006034232A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnostic marker
marker
diagnostic
cardiac ischemia
inflammatory peptide
Prior art date
Application number
PCT/US2005/033548
Other languages
French (fr)
Other versions
WO2006034232A2 (en
Inventor
Salwa A Elgebaly
Paul Sheard
Original Assignee
Nour Heart Inc
Salwa A Elgebaly
Paul Sheard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/945,442 external-priority patent/US7659091B2/en
Application filed by Nour Heart Inc, Salwa A Elgebaly, Paul Sheard filed Critical Nour Heart Inc
Publication of WO2006034232A2 publication Critical patent/WO2006034232A2/en
Publication of WO2006034232A3 publication Critical patent/WO2006034232A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction

Abstract

An inflammatory peptide can be a marker for cardiac ischemia.
PCT/US2005/033548 2004-09-21 2005-09-21 Diagnostic marker WO2006034232A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/945,442 US7659091B2 (en) 2004-09-21 2004-09-21 Diagnostic marker
US10/945,442 2004-09-21
US10/994,521 2004-11-23
US10/994,521 US20060063199A1 (en) 2004-09-21 2004-11-23 Diagnostic marker

Publications (2)

Publication Number Publication Date
WO2006034232A2 WO2006034232A2 (en) 2006-03-30
WO2006034232A3 true WO2006034232A3 (en) 2006-06-22

Family

ID=36000877

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/033548 WO2006034232A2 (en) 2004-09-21 2005-09-21 Diagnostic marker

Country Status (2)

Country Link
US (1) US20060063199A1 (en)
WO (1) WO2006034232A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7331010B2 (en) * 2004-10-29 2008-02-12 International Business Machines Corporation System, method and storage medium for providing fault detection and correction in a memory subsystem
US8158374B1 (en) 2006-09-05 2012-04-17 Ridge Diagnostics, Inc. Quantitative diagnostic methods using multiple parameters
EP1935378B1 (en) * 2006-12-19 2014-09-17 Sorin Group Italia S.r.l. Instrument for in situ positioning of cardiac valve prostheses
US8070799B2 (en) * 2006-12-19 2011-12-06 Sorin Biomedica Cardio S.R.L. Instrument and method for in situ deployment of cardiac valve prostheses
US8808367B2 (en) * 2007-09-07 2014-08-19 Sorin Group Italia S.R.L. Prosthetic valve delivery system including retrograde/antegrade approach
US8114154B2 (en) 2007-09-07 2012-02-14 Sorin Biomedica Cardio S.R.L. Fluid-filled delivery system for in situ deployment of cardiac valve prostheses
CA2740736A1 (en) * 2008-10-15 2010-04-22 Ridge Diagnostics, Inc. Human biomarker hypermapping for depressive disorders
EP2356453A4 (en) * 2008-11-18 2012-08-15 Ridge Diagnostics Inc Metabolic syndrome and hpa axis biomarkers for major depressive disorder
WO2010118035A2 (en) * 2009-04-06 2010-10-14 Ridge Diagnostics, Inc. Biomarkers for monitoring treatment of neuropsychiatric diseases
US8403982B2 (en) * 2009-05-13 2013-03-26 Sorin Group Italia S.R.L. Device for the in situ delivery of heart valves
US8353953B2 (en) * 2009-05-13 2013-01-15 Sorin Biomedica Cardio, S.R.L. Device for the in situ delivery of heart valves
US9168105B2 (en) * 2009-05-13 2015-10-27 Sorin Group Italia S.R.L. Device for surgical interventions
JP5744063B2 (en) * 2010-01-26 2015-07-01 リッジ ダイアグノスティックス，インコーポレイテッド Multiple biomarker panels for stratifying the disease severity of depression and monitoring treatment
US20120303048A1 (en) 2011-05-24 2012-11-29 Sorin Biomedica Cardio S.R.I. Transapical valve replacement
US20130078646A1 (en) * 2011-09-26 2013-03-28 Nour Heart, Inc. Antibodies, compositions, and assays for detection of cardiac disease
CN103954778A (en) * 2014-05-22 2014-07-30 江苏金标世纪生物科技有限公司 Myocardial infarction triple rapid detection kit and preparation method for same
WO2019075404A2 (en) * 2017-10-13 2019-04-18 The Metrohealth System Igf-1 (insulin-like growth factor) as therapy for cardiac arrhythmias
AU2018424859B2 (en) 2018-05-23 2024-04-04 Corcym S.R.L. A cardiac valve prosthesis
US11761966B2 (en) 2018-06-18 2023-09-19 Nour Heart, Inc. Nourin gene-based RNA molecular network: novel early diagnostic and prognostic biomarkers for coronary artery disease, unstable angina, STEMI/NSTEMI and heart failure
US11654134B2 (en) 2018-06-18 2023-05-23 Nour Heart, Inc. Cyclocreatine phosphate: a novel bioenergetic therapy to prevent and treat ischemia-induced and aging-related cardiovascular and neurodegenerative diseases
US10895572B2 (en) * 2018-06-18 2021-01-19 Nour Heart, Inc. Autophagy-related nourin gene-based RNA network as early biomarkers for cardiac patients
CA3162195A1 (en) * 2019-12-18 2021-06-24 Salwa A. Elgebaly Nourin gene-based rna molecular network: novel early diagnostic and prognostic biomarkers for coronary artery disease, unstable angina, stemi/nstemi and heart failure

Citations (2)

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Publication number Priority date Publication date Assignee Title
US5606027A (en) * 1987-10-09 1997-02-25 Elgebaly; Salwa A. Antibodies to a neutrophil chemotactic protein
WO2002066510A2 (en) * 2001-02-20 2002-08-29 K.U. Leuven Research And Development Regakine-1

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US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US5403914A (en) * 1987-10-09 1995-04-04 The University Of Connecticut Biological mediators of immune functions
US5270163A (en) * 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
DK0653639T3 (en) * 1993-11-12 2000-07-24 Unilever Nv Analytical devices and methods for their use
DK0653625T3 (en) * 1993-11-12 2003-01-13 Inverness Medical Switzerland Test strip reading devices
GB9419267D0 (en) * 1994-09-23 1994-11-09 Unilever Plc Assay devices

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5606027A (en) * 1987-10-09 1997-02-25 Elgebaly; Salwa A. Antibodies to a neutrophil chemotactic protein
WO2002066510A2 (en) * 2001-02-20 2002-08-29 K.U. Leuven Research And Development Regakine-1

Non-Patent Citations (17)

* Cited by examiner, † Cited by third party
Title
ADAMS JESSE: "Markers to define ischemia: are they ready for prime time use in patients with acute coronary syndromes?", CURRENT CARDIOLOGY REPORTS. JUL 2004, vol. 6, no. 4, July 2004 (2004-07-01), pages 253 - 258, XP002373418, ISSN: 1523-3782 *
CHRISTENSON R H ET AL: "Biochemical markers of the acute coronary syndromes", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, US, vol. 44, no. 8 PART 2, August 1998 (1998-08-01), pages 1855 - 1864, XP002224555, ISSN: 0009-9147 *
DATABASE Geneseq [online] 19 June 2003 (2003-06-19), "Protein encoded by Prokaryotic essential gene #18469.", XP002373440, retrieved from EBI accession no. GSP:ABU32942 Database accession no. ABU32942 *
DATABASE Geneseq [online] 19 June 2003 (2003-06-19), "Protein encoded by Prokaryotic essential gene #3467.", XP002373445, retrieved from EBI accession no. GSP:ABU17940 Database accession no. ABU17940 *
DATABASE Geneseq [online] 19 June 2003 (2003-06-19), "Protein encoded by Prokaryotic essential gene #8732.", XP002373441, retrieved from EBI accession no. GSP:ABU23205 Database accession no. ABU23205 *
DATABASE Geneseq [online] 21 March 2000 (2000-03-21), "Neisseria meningitidis ORF 993 protein sequence SEQ ID NO:3004.", XP002373438, retrieved from EBI accession no. GSP:AAY75766 Database accession no. AAY75766 *
DATABASE Geneseq [online] 21 May 1999 (1999-05-21), "S.aureus greA protein fragment.", XP002373439, retrieved from EBI accession no. GSP:AAW78485 Database accession no. AAW78485 *
DATABASE UniProt [online] 1 April 1993 (1993-04-01), "Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase).", XP002373443, retrieved from EBI accession no. UNIPROT:NADC_SALTY Database accession no. P30012 *
DATABASE UniProt [online] 1 June 2002 (2002-06-01), "Protein crcB homolog 3.", XP002373444, retrieved from EBI accession no. UNIPROT:CRCB3_METAC Database accession no. Q8TIQ3 *
DATABASE UniProt [online] 1 June 2003 (2003-06-01), "Blr2264 protein.", XP002373435, retrieved from EBI accession no. UNIPROT:Q89SY6 Database accession no. Q89SY6 *
DATABASE UniProt [online] 1 June 2003 (2003-06-01), "Patatin.", XP002373436, retrieved from EBI accession no. UNIPROT:Q82SM1 Database accession no. Q82SM1 *
DATABASE UniProt [online] 1 March 2002 (2002-03-01), "Riboflavin biosynthesis protein.", XP002373446, retrieved from EBI accession no. UNIPROT:Q8XMX2 Database accession no. Q8XMX2 *
DATABASE UniProt [online] 1 March 2003 (2003-03-01), "Hypothetical protein P0011H09.134.", XP002373448, retrieved from EBI accession no. UNIPROT:Q8H4E3 Database accession no. Q8H4E3 *
DATABASE UniProt [online] 1 May 2000 (2000-05-01), "34 kDa periplasmic flagella core protein (Fragment).", XP002373447, retrieved from EBI accession no. UNIPROT:Q9R5K3 Database accession no. Q9R5K3 *
DATABASE UniProt [online] 1 May 2000 (2000-05-01), "NADH dehydrogenase (Fragment).", XP002373442, retrieved from EBI accession no. UNIPROT:Q9TMX5 Database accession no. Q9TMX5 *
DATABASE UniProt [online] 15 December 2003 (2003-12-15), "Predicted protein.", XP002373434, retrieved from EBI accession no. UNIPROT:Q7SBS3 Database accession no. Q7SBS3 *
DATABASE UniProt [online] 23 November 2004 (2004-11-23), "TrbP protein.", XP002373437, retrieved from EBI accession no. UNIPROT:Q5ZHG7 Database accession no. Q5ZHG7 *

Also Published As

Publication number Publication date
WO2006034232A2 (en) 2006-03-30
US20060063199A1 (en) 2006-03-23

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