WO2006023130A3 - Biodegradable controlled release bioactive agent delivery device - Google Patents

Biodegradable controlled release bioactive agent delivery device Download PDF

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Publication number
WO2006023130A3
WO2006023130A3 PCT/US2005/023973 US2005023973W WO2006023130A3 WO 2006023130 A3 WO2006023130 A3 WO 2006023130A3 US 2005023973 W US2005023973 W US 2005023973W WO 2006023130 A3 WO2006023130 A3 WO 2006023130A3
Authority
WO
WIPO (PCT)
Prior art keywords
bioactive agent
delivery device
controlled release
agent delivery
release bioactive
Prior art date
Application number
PCT/US2005/023973
Other languages
French (fr)
Other versions
WO2006023130A2 (en
Inventor
Laurie R Lawin
Aron B Anderson
Original Assignee
Surmodics Inc
Laurie R Lawin
Aron B Anderson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surmodics Inc, Laurie R Lawin, Aron B Anderson filed Critical Surmodics Inc
Publication of WO2006023130A2 publication Critical patent/WO2006023130A2/en
Publication of WO2006023130A3 publication Critical patent/WO2006023130A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body

Abstract

The invention provides implantable medical devices that are fabricated, at least in part, from biodegradable polymeric material. The implantable medical devices are used to provide bioactive agent to a treatment site, and are particularly useful for treatment of limited access regions of the body.
PCT/US2005/023973 2004-08-12 2005-07-05 Biodegradable controlled release bioactive agent delivery device WO2006023130A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60093004P 2004-08-12 2004-08-12
US60/600,930 2004-08-12

Publications (2)

Publication Number Publication Date
WO2006023130A2 WO2006023130A2 (en) 2006-03-02
WO2006023130A3 true WO2006023130A3 (en) 2006-08-03

Family

ID=35149022

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/023973 WO2006023130A2 (en) 2004-08-12 2005-07-05 Biodegradable controlled release bioactive agent delivery device

Country Status (2)

Country Link
US (1) US20060034891A1 (en)
WO (1) WO2006023130A2 (en)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2328830C (en) * 1998-04-13 2012-07-24 Rutgers, The State University The construction of copolymer libraries
US7585517B2 (en) * 2003-09-18 2009-09-08 Macusight, Inc. Transscleral delivery
US9051411B2 (en) 2004-08-16 2015-06-09 Lawrence Livermore National Security, Llc Shape memory polymers
US11820852B2 (en) 2004-08-16 2023-11-21 Lawrence Livermore National Security, Llc Shape memory polymers
US7419504B2 (en) * 2004-12-27 2008-09-02 Advanced Cardiovascular Systems, Inc. Poly(ester amide) block copolymers
US8663639B2 (en) * 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
SI1848431T1 (en) * 2005-02-09 2016-05-31 Santen Pharmaceutical Co., Ltd. Liquid formulations for treatment of diseases or conditions
EP1868661A1 (en) * 2005-04-08 2007-12-26 SurModics, Inc. Sustained release implants for subretinal delivery
JP5528708B2 (en) 2006-02-09 2014-06-25 参天製薬株式会社 Stable formulations and methods for preparing and using them
US8222271B2 (en) * 2006-03-23 2012-07-17 Santen Pharmaceutical Co., Ltd. Formulations and methods for vascular permeability-related diseases or conditions
US7909789B2 (en) 2006-06-26 2011-03-22 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
EP2083764B1 (en) * 2006-10-17 2015-08-26 Rutgers, The State University N-substituted monomers and polymers
US20100004124A1 (en) * 2006-12-05 2010-01-07 David Taft Systems and methods for delivery of materials for agriculture and aquaculture
US20090246155A1 (en) * 2006-12-05 2009-10-01 Landec Corporation Compositions and methods for personal care
US20090263346A1 (en) * 2006-12-05 2009-10-22 David Taft Systems and methods for delivery of drugs
EP2500015A1 (en) * 2006-12-05 2012-09-19 Landec Corporation Delivery of drugs
US8399007B2 (en) * 2006-12-05 2013-03-19 Landec Corporation Method for formulating a controlled-release pharmaceutical formulation
US20080265343A1 (en) * 2007-04-26 2008-10-30 International Business Machines Corporation Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
US8114883B2 (en) * 2007-12-04 2012-02-14 Landec Corporation Polymer formulations for delivery of bioactive materials
AU2009217337B2 (en) * 2008-02-21 2013-10-10 Rutgers, The State University Of New Jersey Compositions and methods for treating ophthalmic diseases
US8202531B2 (en) * 2008-07-23 2012-06-19 Warsaw Orthopedic, Inc. Drug depots having one or more anchoring members
EP2349981A4 (en) 2008-10-11 2016-11-30 Univ Rutgers Biocompatible polymers for medical devices
US20100249783A1 (en) * 2009-03-24 2010-09-30 Warsaw Orthopedic, Inc. Drug-eluting implant cover
US9078712B2 (en) * 2009-04-15 2015-07-14 Warsaw Orthopedic, Inc. Preformed drug-eluting device to be affixed to an anterior spinal plate
US9414864B2 (en) 2009-04-15 2016-08-16 Warsaw Orthopedic, Inc. Anterior spinal plate with preformed drug-eluting device affixed thereto
CN102596097B (en) 2009-06-03 2015-05-20 弗赛特实验室有限责任公司 Anterior segment drug delivery
US8415449B2 (en) 2009-07-31 2013-04-09 Rutgers, The State University Of New Jersey Bioresorbable polymers synthesized from monomer analogs of natural metabolites
JP6031355B2 (en) 2009-10-11 2016-11-24 ラトガース，ザ ステート ユニバーシティ オブ ニュー ジャージー Biocompatible polymers for medical devices
EP2590605A1 (en) 2010-07-09 2013-05-15 Board of Regents of the University of Texas System Biodegradable scaffolds
EP4245370A3 (en) 2010-07-12 2023-11-29 University of Southern California Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same
US8877489B2 (en) 2011-12-05 2014-11-04 California Institute Of Technology Ultrathin parylene-C semipermeable membranes for biomedical applications
KR102071083B1 (en) 2011-09-14 2020-01-29 포사이트 비젼5, 인크. Ocular insert apparatus and methods
US20130149351A1 (en) * 2011-12-09 2013-06-13 University Of Southern California Polymer scaffolds and their use in the treatment of vision loss
US20150037262A1 (en) * 2012-01-27 2015-02-05 Ecole Polytechnique Federale De Lausanne (Epfl) Device for the transplantation of cells in suspension
EP3312155B1 (en) 2012-02-03 2020-08-05 Rutgers, The State University of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
US11472918B2 (en) 2012-02-03 2022-10-18 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
WO2013123509A1 (en) * 2012-02-17 2013-08-22 Bacterin International, Inc. Adjustable bioactive agent dispersion within a polymeric coating
ES2961369T3 (en) 2012-03-20 2024-03-11 Sight Sciences Inc Eye delivery systems
CN104884006B (en) 2012-10-26 2017-12-15 弗赛特影像5股份有限公司 Ophthalmic system for sustained release drugs to eyes
CN107108863B (en) 2014-12-23 2021-03-19 新泽西鲁特格斯州立大学 Biocompatible diphenoliodide monomers and polymers
US10774030B2 (en) 2014-12-23 2020-09-15 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
US10299958B2 (en) 2015-03-31 2019-05-28 Sight Sciences, Inc. Ocular delivery systems and methods
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
CN107774265A (en) * 2017-10-23 2018-03-09 肇庆高新区国专科技有限公司 A kind of nano ceramics catalyst for being used to be acylated
US11864990B2 (en) 2019-02-26 2024-01-09 Avedro, Inc. Bioresorbable corneal implants
US11504270B1 (en) 2019-09-27 2022-11-22 Sight Sciences, Inc. Ocular delivery systems and methods
WO2022251710A2 (en) * 2021-05-28 2022-12-01 Sight Sciences, Inc. Intraocular devices, systems, and methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002017831A2 (en) * 2000-08-30 2002-03-07 John Hopkins University Devices for intraocular drug delivery
WO2004098565A2 (en) * 2003-05-02 2004-11-18 Surmodics, Inc. Implantable controlled release bioactive agent delivery device

Family Cites Families (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3491060A (en) * 1967-07-11 1970-01-20 Bayer Ag Polyimidocarbonic esters and their preparation
US4000745A (en) * 1968-08-05 1977-01-04 Goldberg Edward M Electrical leads for cardiac stimulators and related methods and means
US4206756A (en) * 1977-03-23 1980-06-10 Murray Grossan Jet ear irrigation system
US4146036A (en) * 1977-10-06 1979-03-27 Medtronic, Inc. Body-implantable lead with protector for tissue securing means
US4209019A (en) * 1979-01-05 1980-06-24 Medtronic, Inc. Stylet insertion guide and rotation control device for use with body implantable lead
EP0064366A1 (en) * 1981-04-29 1982-11-10 Beecham Group Plc Pharmaceutical compositions
US4678466A (en) * 1981-06-25 1987-07-07 Rosenwald Peter L Internal medication delivery method and vehicle
US4863735A (en) * 1985-02-19 1989-09-05 Massachusetts Institute Of Technology Biodegradable polymeric drug delivery system with adjuvant activity
US4638045A (en) * 1985-02-19 1987-01-20 Massachusetts Institute Of Technology Non-peptide polyamino acid bioerodible polymers
US4806621A (en) * 1986-01-21 1989-02-21 Massachusetts Institute Of Technology Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article
US4819661A (en) * 1987-10-26 1989-04-11 Cardiac Pacemakers, Inc. Positive fixation cardiac electrode with drug elution capabilities
US5003992A (en) * 1989-08-23 1991-04-02 Holleman Timothy W Atraumatic screw-in lead
US4953564A (en) * 1989-08-23 1990-09-04 Medtronic, Inc. Screw-in drug eluting lead
US5002067A (en) * 1989-08-23 1991-03-26 Medtronic, Inc. Medical electrical lead employing improved penetrating electrode
US5255693A (en) * 1989-11-02 1993-10-26 Possis Medical, Inc. Cardiac lead
US5219564A (en) * 1990-07-06 1993-06-15 Enzon, Inc. Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
US5216115A (en) * 1990-06-12 1993-06-01 Rutgers, The State University Of New Jersey Polyarylate containing derivatives of the natural amino acid L-tyrosine
US5099060A (en) * 1990-06-12 1992-03-24 Rutgers, The State University Of New Jersey Synthesis of amino acid-derived bioerodible polymers
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5324325A (en) * 1991-06-27 1994-06-28 Siemens Pacesetter, Inc. Myocardial steroid releasing lead
US5178635A (en) * 1992-05-04 1993-01-12 Allergan, Inc. Method for determining amount of medication in an implantable device
IT1259100B (en) * 1992-05-20 1996-03-11 Lanfranco Callegaro USE OF HYDROGELS FOR THE LOCKING OF PROSTHETIC SYSTEMS
US5300108A (en) * 1993-01-05 1994-04-05 Telectronics Pacing Systems, Inc. Active fixation lead with a dual-pitch, free spinning compound screw
US5921982A (en) * 1993-07-30 1999-07-13 Lesh; Michael D. Systems and methods for ablating body tissue
AU7404994A (en) * 1993-07-30 1995-02-28 Regents Of The University Of California, The Endocardial infusion catheter
US5385148A (en) * 1993-07-30 1995-01-31 The Regents Of The University Of California Cardiac imaging and ablation catheter
US5807395A (en) * 1993-08-27 1998-09-15 Medtronic, Inc. Method and apparatus for RF ablation and hyperthermia
US5405376A (en) * 1993-08-27 1995-04-11 Medtronic, Inc. Method and apparatus for ablation
US5431649A (en) * 1993-08-27 1995-07-11 Medtronic, Inc. Method and apparatus for R-F ablation
US5582616A (en) * 1994-08-05 1996-12-10 Origin Medsystems, Inc. Surgical helical fastener with applicator
US5554114A (en) * 1994-10-20 1996-09-10 Micro Therapeutics, Inc. Infusion device with preformed shape
US5725493A (en) * 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
IL113723A (en) * 1995-05-14 2002-11-10 Optonol Ltd Intraocular implant
US6117456A (en) * 1995-05-19 2000-09-12 Etex Corporation Methods and products related to the physical conversion of reactive amorphous calcium phosphate
US5877224A (en) * 1995-07-28 1999-03-02 Rutgers, The State University Of New Jersey Polymeric drug formulations
US5658995A (en) * 1995-11-27 1997-08-19 Rutgers, The State University Copolymers of tyrosine-based polycarbonate and poly(alkylene oxide)
US5810836A (en) * 1996-03-04 1998-09-22 Myocardial Stents, Inc. Device and method for trans myocardial revascularization (TMR)
US5904144A (en) * 1996-03-22 1999-05-18 Cytotherapeutics, Inc. Method for treating ophthalmic diseases
US5928662A (en) * 1996-07-31 1999-07-27 Phillips; Andrew F. Ocular drug delivery device
US6053924A (en) * 1996-11-07 2000-04-25 Hussein; Hany Device and method for trans myocardial revascularization
US6395302B1 (en) * 1996-11-19 2002-05-28 Octoplus B.V. Method for the preparation of microspheres which contain colloidal systems
US6048521A (en) * 1997-11-07 2000-04-11 Rutgers, The State University Copolymers of tyrosine-based polyarlates and poly(alkylene oxides)
US6120491A (en) * 1997-11-07 2000-09-19 The State University Rutgers Biodegradable, anionic polymers derived from the amino acid L-tyrosine
DE69821600T2 (en) * 1997-02-18 2005-01-05 Rutgers, The State University MONOMERS DERIVED FROM HYDROXYLIC ACIDS AND POLYMERS MANUFACTURED THEREOF
US6086582A (en) * 1997-03-13 2000-07-11 Altman; Peter A. Cardiac drug delivery system
US6547787B1 (en) * 1997-03-13 2003-04-15 Biocardia, Inc. Drug delivery catheters that attach to tissue and methods for their use
ES2205462T3 (en) * 1997-03-31 2004-05-01 Alza Corporation DUFUSION SUPPLY SYSTEM, IMPLANTABLE.
AU741145B2 (en) * 1997-04-03 2001-11-22 Eisai Inc. Biodegradable terephthalate polyester-poly(phosphate) polymers, compositions, articles, and methods for making and using the same
WO1998046289A1 (en) * 1997-04-16 1998-10-22 White Spot Ag Biodegradable osteosynthesis implant
KR20010020536A (en) * 1997-06-27 2001-03-15 인테그라 라이프사이언시스 아이, 리미티드 Biphasic polymerization process
DE69827138T2 (en) * 1997-08-11 2006-02-23 Allergan, Inc., Irvine Sterile retinoid-containing biodegradable implant with improved biocompatibility and process for its preparation
US5972027A (en) * 1997-09-30 1999-10-26 Scimed Life Systems, Inc Porous stent drug delivery system
US5980548A (en) * 1997-10-29 1999-11-09 Kensey Nash Corporation Transmyocardial revascularization system
US6602497B1 (en) * 1997-11-07 2003-08-05 Rutgers, The State University Strictly alternating poly(alkylene oxide ether) copolymers
US6212434B1 (en) * 1998-07-22 2001-04-03 Cardiac Pacemakers, Inc. Single pass lead system
US6197324B1 (en) * 1997-12-18 2001-03-06 C. R. Bard, Inc. System and methods for local delivery of an agent
US6251418B1 (en) * 1997-12-18 2001-06-26 C.R. Bard, Inc. Systems and methods for local delivery of an agent
US6091978A (en) * 1998-04-07 2000-07-18 Cardiac Pacemakers, Inc. Removable cap for tissue-insertable connections
AU760408B2 (en) * 1998-04-27 2003-05-15 Surmodics, Inc. Bioactive agent release coating
US6102887A (en) * 1998-08-11 2000-08-15 Biocardia, Inc. Catheter drug delivery system and method for use
US6290728B1 (en) * 1998-09-10 2001-09-18 Percardia, Inc. Designs for left ventricular conduit
US6248112B1 (en) * 1998-09-30 2001-06-19 C. R. Bard, Inc. Implant delivery system
US6656489B1 (en) * 1999-02-10 2003-12-02 Isotis N.V. Scaffold for tissue engineering cartilage having outer surface layers of copolymer and ceramic material
JP4616949B2 (en) * 1999-03-17 2011-01-19 Ｓｕｍｃｏ Ｔｅｃｈｘｉｖ株式会社 Melt level detection apparatus and detection method
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6298272B1 (en) * 1999-03-29 2001-10-02 Cardiac Pacemakers, Inc. High impedance electrode tip with internal drug delivery capability
US6103255A (en) * 1999-04-16 2000-08-15 Rutgers, The State University Porous polymer scaffolds for tissue engineering
US6368346B1 (en) * 1999-06-03 2002-04-09 American Medical Systems, Inc. Bioresorbable stent
US6719805B1 (en) * 1999-06-09 2004-04-13 C. R. Bard, Inc. Devices and methods for treating tissue
WO2001008717A1 (en) * 1999-08-03 2001-02-08 Smith & Nephew, Inc. Controlled release implantable devices
EP1104681A1 (en) * 1999-12-03 2001-06-06 Biomat B.V. Wire, tube or catheter with hydrophilic coating
US6706023B1 (en) * 1999-12-03 2004-03-16 Bionix Development Corporation Device for irrigation of a blind orifice
US6360129B1 (en) * 1999-12-13 2002-03-19 Cardiac Pacemakers, Inc. Mannitol/hydrogel cap for tissue-insertable connections
US6638239B1 (en) * 2000-04-14 2003-10-28 Glaukos Corporation Apparatus and method for treating glaucoma
US6306423B1 (en) * 2000-06-02 2001-10-23 Allergan Sales, Inc. Neurotoxin implant
US6613017B1 (en) * 2000-08-08 2003-09-02 Scimed Life Systems, Inc. Controlled depth injection device and method
US6595958B1 (en) * 2000-08-08 2003-07-22 Scimed Life Systems, Inc. Tortuous path injection device and method
US6709452B1 (en) * 2000-08-21 2004-03-23 Linvatec Biomaterial Oy Biodegradable surgical implants
US6713081B2 (en) * 2001-03-15 2004-03-30 The United States Of America As Represented By The Department Of Health And Human Services Ocular therapeutic agent delivery devices and methods for making and using such devices
US20040022853A1 (en) * 2001-04-26 2004-02-05 Control Delivery Systems, Inc. Polymer-based, sustained release drug delivery system
US20030069629A1 (en) * 2001-06-01 2003-04-10 Jadhav Balkrishna S. Bioresorbable medical devices
EP2316394B1 (en) * 2001-06-12 2016-11-23 The Johns Hopkins University Reservoir device for intraocular drug delivery
US20050129732A1 (en) * 2001-07-13 2005-06-16 Flow Focusing, Inc. Biodegradable, antibiotic, controlled release tape
US20040142013A1 (en) * 2001-07-13 2004-07-22 Flow Focusing, Inc. Implantable orthopedic surgical devices with controlled release antimicrobial component
US6565884B2 (en) * 2001-09-10 2003-05-20 Interpore Cross International Bone graft material incorporating demineralized bone matrix and lipids
US6916321B2 (en) * 2001-09-28 2005-07-12 Ethicon, Inc. Self-tapping resorbable two-piece bone screw
US6764470B2 (en) * 2001-12-03 2004-07-20 Roland P. Dimick Ear plug medication administration device
JP3962591B2 (en) * 2002-01-16 2007-08-22 キヤノン株式会社 Ink jet printer and control method of ink jet printer
US20040006146A1 (en) * 2002-07-06 2004-01-08 Evans Douglas G. Resorbable structure for treating and healing of tissue defects
US7103418B2 (en) * 2002-10-02 2006-09-05 Medtronic, Inc. Active fluid delivery catheter
US7169178B1 (en) * 2002-11-12 2007-01-30 Advanced Cardiovascular Systems, Inc. Stent with drug coating
US7953499B2 (en) * 2003-09-30 2011-05-31 Cardiac Pacemakers, Inc. Drug-eluting electrode
US7197362B2 (en) * 2003-12-11 2007-03-27 Cardiac Pacemakers, Inc. Cardiac lead having coated fixation arrangement
ATE536154T1 (en) * 2004-02-13 2011-12-15 Innovational Holdings Llc MEDICAL COATING SYSTEM AND COATING PROCESS FOR WIRES
US7378144B2 (en) * 2004-02-17 2008-05-27 Kensey Nash Corporation Oriented polymer implantable device and process for making same
WO2006002399A2 (en) * 2004-06-24 2006-01-05 Surmodics, Inc. Biodegradable implantable medical devices, methods and systems

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002017831A2 (en) * 2000-08-30 2002-03-07 John Hopkins University Devices for intraocular drug delivery
WO2004098565A2 (en) * 2003-05-02 2004-11-18 Surmodics, Inc. Implantable controlled release bioactive agent delivery device

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HOOPER KIMBERLY A ET AL: "Comparative histological evaluation of new tyrosine-derived polymers and poly (L-lactic acid) as a function of polymer degradation", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, vol. 41, no. 3, 5 September 1998 (1998-09-05), pages 443 - 454, XP002380952, ISSN: 0021-9304 *
KOHN J ET AL: "THE EFFECT OF POLYMER STRUCTURE AND FORMULATION TECHNIQUES ON THE RELEASE OF A MODEL PEPTIDE", 1995, PROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE BIOACTIVE MATERIALS, VOL. 22, PAGE(S) 522-523, ISSN: 1022-0178, XP009065791 *
YU C ET AL: "Tyrosine-PEG-derived poly(ether carbonate)s as new biomaterials - Part II: study of inverse temperature transitions", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 20, no. 3, February 1999 (1999-02-01), pages 265 - 272, XP004168902, ISSN: 0142-9612 *

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