WO2006022996A3 - Dosage form containing multiple drugs - Google Patents

Dosage form containing multiple drugs Download PDF

Info

Publication number
WO2006022996A3
WO2006022996A3 PCT/US2005/020499 US2005020499W WO2006022996A3 WO 2006022996 A3 WO2006022996 A3 WO 2006022996A3 US 2005020499 W US2005020499 W US 2005020499W WO 2006022996 A3 WO2006022996 A3 WO 2006022996A3
Authority
WO
WIPO (PCT)
Prior art keywords
dosage form
drug
containing multiple
form containing
multiple drugs
Prior art date
Application number
PCT/US2005/020499
Other languages
French (fr)
Other versions
WO2006022996A2 (en
Inventor
Viswanathan Srinivasan
Ralph Brown
David Brown
Himanshu Patel
Juan Carlos Menendez
Venkatesh Balasubramanian
Somphet Peter Suphasawud
Original Assignee
Sovereign Pharmaceuticals Ltd
Viswanathan Srinivasan
Ralph Brown
David Brown
Himanshu Patel
Juan Carlos Menendez
Venkatesh Balasubramanian
Somphet Peter Suphasawud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/910,806 external-priority patent/US20060029664A1/en
Priority claimed from US10/939,351 external-priority patent/US9492541B2/en
Priority claimed from US11/012,267 external-priority patent/US9592197B2/en
Priority claimed from US11/102,726 external-priority patent/US20070003622A1/en
Priority claimed from US11/102,725 external-priority patent/US20050281875A1/en
Priority claimed from US11/115,293 external-priority patent/US20050232993A1/en
Priority claimed from US11/115,321 external-priority patent/US20050266032A1/en
Application filed by Sovereign Pharmaceuticals Ltd, Viswanathan Srinivasan, Ralph Brown, David Brown, Himanshu Patel, Juan Carlos Menendez, Venkatesh Balasubramanian, Somphet Peter Suphasawud filed Critical Sovereign Pharmaceuticals Ltd
Publication of WO2006022996A2 publication Critical patent/WO2006022996A2/en
Publication of WO2006022996A3 publication Critical patent/WO2006022996A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

A pharmaceutical dosage form comprising a first drug and a second drug, both of which are selected from decongestants, antitussives, expectorants, analgesics and antihistamines. The dosage form provides a plasma concentration within a therapeutic range of the second drug over a period which is coextensive with at least about 70% of a period over which the dosage form provides a plasma concentration within a therapeutic range of the first drug.
PCT/US2005/020499 2004-08-04 2005-06-13 Dosage form containing multiple drugs WO2006022996A2 (en)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US10/910,806 US20060029664A1 (en) 2004-08-04 2004-08-04 Dosage form containing carbetapentane and another drug
US10/910,806 2004-08-04
US10/939,351 US9492541B2 (en) 2004-09-14 2004-09-14 Phenylepherine containing dosage form
US10/939,351 2004-09-14
US11/012,267 US9592197B2 (en) 2004-12-16 2004-12-16 Dosage form containing diphenhydramine and another drug
US11/012,267 2004-12-16
US11/102,725 2005-04-11
US11/102,726 US20070003622A1 (en) 2004-12-16 2005-04-11 Diphenhydramine containing dosage form
US11/102,725 US20050281875A1 (en) 2003-12-17 2005-04-11 Promethazine containing dosage form
US11/102,726 2005-04-11
US11/115,293 US20050232993A1 (en) 2003-12-17 2005-04-27 Dosage form containing promethazine and another drug
US11/115,293 2005-04-27
US11/115,321 2005-04-27
US11/115,321 US20050266032A1 (en) 2003-12-17 2005-04-27 Dosage form containing multiple drugs

Publications (2)

Publication Number Publication Date
WO2006022996A2 WO2006022996A2 (en) 2006-03-02
WO2006022996A3 true WO2006022996A3 (en) 2006-12-21

Family

ID=35968002

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/020499 WO2006022996A2 (en) 2004-08-04 2005-06-13 Dosage form containing multiple drugs

Country Status (1)

Country Link
WO (1) WO2006022996A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8653066B2 (en) 2006-10-09 2014-02-18 Charleston Laboratories, Inc. Pharmaceutical compositions
US8728522B2 (en) 2009-07-08 2014-05-20 Charleston Laboratories, Inc. Pharmaceutical compositions for treating or preventing pain
US9198867B2 (en) 2008-01-09 2015-12-01 Charleston Laboratories, Inc. Pharmaceutical compositions
US9198864B2 (en) 2006-03-16 2015-12-01 Tris Pharma, Inc Modified release formulations containing drug-ion exchange resin complexes

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8940796B2 (en) 2006-02-21 2015-01-27 Wyeth Llc Phenylephrine liquid formulations
US20070249727A1 (en) 2006-04-21 2007-10-25 The Proctor & Gamble Company Compositions and kits useful for treatment of respiratory illness
US10022339B2 (en) 2006-04-21 2018-07-17 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
US20080014274A1 (en) 2006-07-14 2008-01-17 Wyeth Enhanced stability phenylephrine liquid compositions
US8765178B2 (en) 2006-07-19 2014-07-01 Watson Laboratories, Inc. Controlled release formulations and associated methods
BRPI0719021A2 (en) 2006-11-21 2013-12-17 Mcneil Ppc Inc ANALGESIC SUSPENSIONS OF MODIFIED RELEASE.
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
CA2696341C (en) * 2007-08-13 2016-05-17 Abuse Deterrent Pharmaceutical Llc Abuse resistant drugs, method of use and method of making
US9078824B2 (en) * 2007-09-24 2015-07-14 The Procter & Gamble Company Composition and method of stabilized sensitive ingredient
TWI394594B (en) * 2009-03-06 2013-05-01 China Chemical & Pharmaceutical Co Ltd Pharmaceutical tablet composition and manufacturing method thereof
BR112015003120B1 (en) 2012-08-15 2022-08-09 Tris Pharma , Inc METHYLPHENIDATE EXTENDED RELEASE CHEW TABLET AND ITS USE
US11590228B1 (en) 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
WO2017152130A1 (en) 2016-03-04 2017-09-08 Charleston Laboratories, Inc. Pharmaceutical compositions
US20170354603A1 (en) * 2016-06-10 2017-12-14 Charleston Laboratories, Inc. Pharmaceutical compositions
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
EP4081187B1 (en) 2019-12-23 2023-12-13 Nutra Essential OTC, S.L. Liquid composition comprising ibuprofen and phenylephrine
US11918689B1 (en) 2020-07-28 2024-03-05 Tris Pharma Inc Liquid clonidine extended release composition
CN116496205A (en) * 2022-05-06 2023-07-28 成都施贝康生物医药科技有限公司 Cardustatin salt and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6699502B1 (en) * 1997-03-14 2004-03-02 Ucb, S.A. Pharmaceutical compositions for controlled release of active substances
US6797283B1 (en) * 1998-12-23 2004-09-28 Alza Corporation Gastric retention dosage form having multiple layers

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6699502B1 (en) * 1997-03-14 2004-03-02 Ucb, S.A. Pharmaceutical compositions for controlled release of active substances
US6797283B1 (en) * 1998-12-23 2004-09-28 Alza Corporation Gastric retention dosage form having multiple layers

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9198864B2 (en) 2006-03-16 2015-12-01 Tris Pharma, Inc Modified release formulations containing drug-ion exchange resin complexes
US9549989B2 (en) 2006-03-16 2017-01-24 Tris Pharma, Inc Modified release formulations containing drug-ion exchange resin complexes
US9522191B2 (en) 2006-03-16 2016-12-20 Tris Pharma, Inc. Modified release formulations containing drug—ion exchange resin complexes
US9393207B2 (en) 2006-10-09 2016-07-19 Locl Pharma, Inc. Pharmaceutical compositions
US8653066B2 (en) 2006-10-09 2014-02-18 Charleston Laboratories, Inc. Pharmaceutical compositions
US9399022B2 (en) 2006-10-09 2016-07-26 Locl Pharma, Inc. Pharmaceutical compositions
US9402813B2 (en) 2006-10-09 2016-08-02 Locl Pharma, Inc. Pharmaceutical compositions
US9427407B2 (en) 2006-10-09 2016-08-30 Locl Pharma, Inc. Pharmaceutical compositions
US9226901B2 (en) 2008-01-09 2016-01-05 Locl Pharma, Inc. Pharmaceutical compositions
US9387177B2 (en) 2008-01-09 2016-07-12 Locl Pharma, Inc. Pharmaceutical compositions
US9498444B2 (en) 2008-01-09 2016-11-22 Locl Pharma, Inc. Pharmaceutical compositions
US9198867B2 (en) 2008-01-09 2015-12-01 Charleston Laboratories, Inc. Pharmaceutical compositions
US9433625B2 (en) 2009-07-08 2016-09-06 Locl Pharma, Inc. Pharmaceutical compositions for treating or preventing pain
US9526704B2 (en) 2009-07-08 2016-12-27 Locl Pharma, Inc. Pharmaceutical compositions for treating or preventing pain
US8728522B2 (en) 2009-07-08 2014-05-20 Charleston Laboratories, Inc. Pharmaceutical compositions for treating or preventing pain

Also Published As

Publication number Publication date
WO2006022996A2 (en) 2006-03-02

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