WO2006007841A3 - Heat-induced antigen retrieval methods and compositions therefor - Google Patents

Heat-induced antigen retrieval methods and compositions therefor Download PDF

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Publication number
WO2006007841A3
WO2006007841A3 PCT/DK2005/000480 DK2005000480W WO2006007841A3 WO 2006007841 A3 WO2006007841 A3 WO 2006007841A3 DK 2005000480 W DK2005000480 W DK 2005000480W WO 2006007841 A3 WO2006007841 A3 WO 2006007841A3
Authority
WO
WIPO (PCT)
Prior art keywords
antigen retrieval
heat
retrieval methods
induced antigen
compositions therefor
Prior art date
Application number
PCT/DK2005/000480
Other languages
French (fr)
Other versions
WO2006007841A2 (en
Inventor
Marc E Key
Scott A Devore
Sandy Krishnamurthy
Loren L Bland
Uffe Lovborg
Original Assignee
Dakocytomation Denmark As
Marc E Key
Scott A Devore
Sandy Krishnamurthy
Loren L Bland
Uffe Lovborg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dakocytomation Denmark As, Marc E Key, Scott A Devore, Sandy Krishnamurthy, Loren L Bland, Uffe Lovborg filed Critical Dakocytomation Denmark As
Priority to EP05757790.0A priority Critical patent/EP1776584B1/en
Publication of WO2006007841A2 publication Critical patent/WO2006007841A2/en
Publication of WO2006007841A3 publication Critical patent/WO2006007841A3/en

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/111666Utilizing a centrifuge or compartmented rotor
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

Abstract

A composition for antigen retrieval comprising at least one chelating agent, at least one detergent and at least 50% by volume of at least one glycol-containing liquid that facilitates antigen retrieval is provided. Also, a method of antigen retrieval comprising contacting at least one biological sample with at least one composition for antigen retrieval comprising at least one chelating agent, at least one detergent and at least 50% by volume of at least one glycol-containing liquid that facilitates antigen retrieval, as well as uses of said compositions are provided.
PCT/DK2005/000480 2004-07-23 2005-07-08 Heat-induced antigen retrieval methods and compositions therefor WO2006007841A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP05757790.0A EP1776584B1 (en) 2004-07-23 2005-07-08 Heat-induced antigen retrieval methods and compositions therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59033204P 2004-07-23 2004-07-23
US60/590,332 2004-07-23

Publications (2)

Publication Number Publication Date
WO2006007841A2 WO2006007841A2 (en) 2006-01-26
WO2006007841A3 true WO2006007841A3 (en) 2006-07-13

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2005/000480 WO2006007841A2 (en) 2004-07-23 2005-07-08 Heat-induced antigen retrieval methods and compositions therefor

Country Status (3)

Country Link
US (1) US7867443B2 (en)
EP (1) EP1776584B1 (en)
WO (1) WO2006007841A2 (en)

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Also Published As

Publication number Publication date
US20060134793A1 (en) 2006-06-22
EP1776584A2 (en) 2007-04-25
US7867443B2 (en) 2011-01-11
WO2006007841A2 (en) 2006-01-26
EP1776584B1 (en) 2016-08-17

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