WO2006007472B1 - Non-invasive glucose measurement - Google Patents

Non-invasive glucose measurement

Info

Publication number
WO2006007472B1
WO2006007472B1 PCT/US2005/022139 US2005022139W WO2006007472B1 WO 2006007472 B1 WO2006007472 B1 WO 2006007472B1 US 2005022139 W US2005022139 W US 2005022139W WO 2006007472 B1 WO2006007472 B1 WO 2006007472B1
Authority
WO
WIPO (PCT)
Prior art keywords
skin patch
skin surface
patch
glucose
patches
Prior art date
Application number
PCT/US2005/022139
Other languages
French (fr)
Other versions
WO2006007472A2 (en
WO2006007472A3 (en
Inventor
Thomas A Peyser
Russel O Potts
Herbert L Berman
James W Moyer
Mikhail A Kouchnir
Original Assignee
Vivomedical Inc
Thomas A Peyser
Russel O Potts
Herbert L Berman
James W Moyer
Mikhail A Kouchnir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vivomedical Inc, Thomas A Peyser, Russel O Potts, Herbert L Berman, James W Moyer, Mikhail A Kouchnir filed Critical Vivomedical Inc
Priority to CA002572313A priority Critical patent/CA2572313A1/en
Priority to EP05762354A priority patent/EP1776035A2/en
Priority to JP2007519286A priority patent/JP2008504881A/en
Priority to MXPA06014896A priority patent/MXPA06014896A/en
Publication of WO2006007472A2 publication Critical patent/WO2006007472A2/en
Publication of WO2006007472A3 publication Critical patent/WO2006007472A3/en
Publication of WO2006007472B1 publication Critical patent/WO2006007472B1/en
Priority to IL180034A priority patent/IL180034A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/14517—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for sweat
    • A61B5/14521—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for sweat using means for promoting sweat production, e.g. heating the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y35/00—Methods or apparatus for measurement or analysis of nanostructures

Abstract

Described are devices, methods, and kits for non-invasively measuring glucose. In general, the devices comprise skin patches for placement on a skin surface and measurement devices for measuring glucose collected in the patches. The patches may include an adhesive material, a collection layer, an interface layer, and a sweat-permeable membrane. The sweat-permeable membrane is configured to act as a barrier to epidermal contaminants and glucose brought to the skin surface via diffusion. In this way, non-correlatable skin surface glucose will not be measured. The patches may further include components to induce a local sweat response. The measurement device typically includes a display, a processor, and a measurement mechanism. The methods typically include the steps of wiping the skin surface with a wipe containing at least one solvent for removing glucose, placing a patch on a skin surface, and measuring glucose collected in the patch. Kits comprising the patch and measurement device are also described.

Claims

AMENDED CLAIMS received by the International Bureau on 27 April 2006 (27.04.06)
7. The skin patch of claim 1 wherein the sweat-permeable membrane comprises an inorganic material with micropores.
8. The skin patch of claim 1 wherein the sweat-permeable membrane comprises a solid polymer with micropores.
9. The skin patch of claim 1 further comprising a backing layer.
10. The skin patch of claim 9 wherein the backing layer is occlusive.
11. The skin patch of claim 1 further comprising a release liner.
12. The skin patch of claim 1 wherein the collection layer further comprises a fixed volume reservoir.
13. The skin patch of claim 12 further comprising an electric circuit through the fixed volume reservoir.
14. The skin patch of claim 13 further comprising at least two conductors.
15. The skin patch of claim 12 further comprising an optical transmission path through the fixed volume reservoir.
16. The skin patch of claim 1 wherein the interface comprises at least one electrode.
17. The skin patch of claim 1 wherein the interface layer is optically transmissive.
18. The skin patch of claim 1 further comprising pilocarpine.
19. The skin patch of claim 17 further comprising a penetration enhancer.
20. The skin patch of claim 1 further comprising a chemical capable of inducing a local temperature increase.
35
PCT/US2005/022139 2004-07-01 2005-06-22 Non-invasive glucose measurement WO2006007472A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002572313A CA2572313A1 (en) 2004-07-01 2005-06-22 Non-invasive glucose measurement
EP05762354A EP1776035A2 (en) 2004-07-01 2005-06-22 Non-invasive glucose measurement
JP2007519286A JP2008504881A (en) 2004-07-01 2005-06-22 Noninvasive glucose measurement
MXPA06014896A MXPA06014896A (en) 2004-07-01 2005-06-22 Non-invasive glucose measurement.
IL180034A IL180034A0 (en) 2004-07-01 2006-12-13 Non-invasive glucose measurement

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58541404P 2004-07-01 2004-07-01
US60/585,414 2004-07-01

Publications (3)

Publication Number Publication Date
WO2006007472A2 WO2006007472A2 (en) 2006-01-19
WO2006007472A3 WO2006007472A3 (en) 2006-06-08
WO2006007472B1 true WO2006007472B1 (en) 2006-07-06

Family

ID=34981671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/022139 WO2006007472A2 (en) 2004-07-01 2005-06-22 Non-invasive glucose measurement

Country Status (10)

Country Link
US (1) US7725149B2 (en)
EP (1) EP1776035A2 (en)
JP (2) JP2008504881A (en)
KR (1) KR20070043768A (en)
CN (2) CN101623199A (en)
AU (1) AU2005262444A1 (en)
CA (1) CA2572313A1 (en)
IL (1) IL180034A0 (en)
MX (1) MXPA06014896A (en)
WO (1) WO2006007472A2 (en)

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US8812071B2 (en) 2007-03-07 2014-08-19 Echo Therapeutics, Inc. Transdermal analyte monitoring systems and methods for analyte detection

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