WO2006000448A3 - Fc-INTERFERON-BETA FUSION PROTEINS - Google Patents
Fc-INTERFERON-BETA FUSION PROTEINS Download PDFInfo
- Publication number
- WO2006000448A3 WO2006000448A3 PCT/EP2005/006925 EP2005006925W WO2006000448A3 WO 2006000448 A3 WO2006000448 A3 WO 2006000448A3 EP 2005006925 W EP2005006925 W EP 2005006925W WO 2006000448 A3 WO2006000448 A3 WO 2006000448A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fusion proteins
- interferon
- beta
- ifn
- nucleic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05766761A EP1761559B1 (en) | 2004-06-28 | 2005-06-28 | Fc-INTERFERON-BETA FUSION PROTEINS |
DE602005016799T DE602005016799D1 (en) | 2004-06-28 | 2005-06-28 | FC INTERFERON BETA FUSION PROTEINS |
JP2007517216A JP4808709B2 (en) | 2004-06-28 | 2005-06-28 | Fc-interferon-beta fusion protein |
AT05766761T ATE443720T1 (en) | 2004-06-28 | 2005-06-28 | FC-INTERFERON-BETA FUSION PROTEINS |
AU2005256519A AU2005256519B2 (en) | 2004-06-28 | 2005-06-28 | Fc-interferon-beta fusion proteins |
CA2572015A CA2572015C (en) | 2004-06-28 | 2005-06-28 | Fc-interferon-beta fusion proteins |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58338904P | 2004-06-28 | 2004-06-28 | |
US60/583,389 | 2004-06-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006000448A2 WO2006000448A2 (en) | 2006-01-05 |
WO2006000448A3 true WO2006000448A3 (en) | 2006-03-02 |
Family
ID=35429166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2005/006925 WO2006000448A2 (en) | 2004-06-28 | 2005-06-28 | Fc-INTERFERON-BETA FUSION PROTEINS |
Country Status (9)
Country | Link |
---|---|
US (3) | US7670595B2 (en) |
EP (1) | EP1761559B1 (en) |
JP (1) | JP4808709B2 (en) |
AT (1) | ATE443720T1 (en) |
AU (1) | AU2005256519B2 (en) |
CA (1) | CA2572015C (en) |
DE (1) | DE602005016799D1 (en) |
ES (1) | ES2332924T3 (en) |
WO (1) | WO2006000448A2 (en) |
Cited By (2)
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CN103570836A (en) * | 2013-10-25 | 2014-02-12 | 江苏众红生物工程创药研究院有限公司 | Recombinant porcine interferon beta1-Fc fusion protein as well as encoding gene and expressing method thereof |
CN104530213A (en) * | 2014-11-24 | 2015-04-22 | 广西大学 | Viral hepatitis treatment drug interferon production technology |
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WO2002079415A2 (en) | 2001-03-30 | 2002-10-10 | Lexigen Pharmaceuticals Corp. | Reducing the immunogenicity of fusion proteins |
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CN103570836A (en) * | 2013-10-25 | 2014-02-12 | 江苏众红生物工程创药研究院有限公司 | Recombinant porcine interferon beta1-Fc fusion protein as well as encoding gene and expressing method thereof |
CN103570836B (en) * | 2013-10-25 | 2016-03-16 | 江苏众红生物工程创药研究院有限公司 | A kind of Recombinant Swine interferon beta 1-Fc fusion rotein and encoding gene thereof and expression method |
CN104530213A (en) * | 2014-11-24 | 2015-04-22 | 广西大学 | Viral hepatitis treatment drug interferon production technology |
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US20060228332A1 (en) | 2006-10-12 |
CA2572015C (en) | 2014-04-22 |
AU2005256519A1 (en) | 2006-01-05 |
ES2332924T3 (en) | 2010-02-15 |
JP4808709B2 (en) | 2011-11-02 |
ATE443720T1 (en) | 2009-10-15 |
US20140005361A1 (en) | 2014-01-02 |
US7670595B2 (en) | 2010-03-02 |
JP2008508862A (en) | 2008-03-27 |
CA2572015A1 (en) | 2006-01-05 |
US8557232B2 (en) | 2013-10-15 |
AU2005256519B2 (en) | 2011-10-13 |
DE602005016799D1 (en) | 2009-11-05 |
WO2006000448A2 (en) | 2006-01-05 |
US20090191154A1 (en) | 2009-07-30 |
EP1761559B1 (en) | 2009-09-23 |
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