WO2005120335A3 - Assay apparatus comprising an implanted light source - Google Patents

Assay apparatus comprising an implanted light source Download PDF

Info

Publication number
WO2005120335A3
WO2005120335A3 PCT/IL2005/000593 IL2005000593W WO2005120335A3 WO 2005120335 A3 WO2005120335 A3 WO 2005120335A3 IL 2005000593 W IL2005000593 W IL 2005000593W WO 2005120335 A3 WO2005120335 A3 WO 2005120335A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood
analyte
light source
light
patient
Prior art date
Application number
PCT/IL2005/000593
Other languages
French (fr)
Other versions
WO2005120335A2 (en
Inventor
Gabriel Bitton
Benny Pesach
Ron Nagar
Original Assignee
Glucon Inc
Gabriel Bitton
Benny Pesach
Ron Nagar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glucon Inc, Gabriel Bitton, Benny Pesach, Ron Nagar filed Critical Glucon Inc
Publication of WO2005120335A2 publication Critical patent/WO2005120335A2/en
Publication of WO2005120335A3 publication Critical patent/WO2005120335A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0026—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the transmission medium
    • A61B5/0028—Body tissue as transmission medium, i.e. transmission systems where the medium is the human body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0031—Implanted circuitry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6862—Stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6876—Blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0204—Operational features of power management
    • A61B2560/0214—Operational features of power management of power generation or supply
    • A61B2560/0219—Operational features of power management of power generation or supply of externally powered implanted units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/07—Endoradiosondes
    • A61B5/076—Permanent implantations

Abstract

Apparatus for assaying an analyte in a patient's blood comprising: at least one light source (22) implanted in the patient's body controllable to illuminate blood in a blood vessel (40) in the body with light at at least one wavelength that is absorbed and/or scattered by the analyte and as a result generates photoacoustic waves in the blood; at least one acoustic transducer (32) coupled to the body that receives acoustic energy from the photoacoustic waves and generates signals responsive thereto; and a processor (34) that receives the signals and processes them to determine a concentration of the analyte in the illuminated tissue region. Another embodiment of the apparatus comprises a light source and an optical detector mounted to a stent and optically coupled by a light pipe wherein light undergoes attenuated total reflection along the light pipe responsive to concentration of the analyte in the blood.
PCT/IL2005/000593 2004-06-07 2005-06-06 Assay apparatus comprising an implanted light source WO2005120335A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57718204P 2004-06-07 2004-06-07
US60/577,182 2004-06-07

Publications (2)

Publication Number Publication Date
WO2005120335A2 WO2005120335A2 (en) 2005-12-22
WO2005120335A3 true WO2005120335A3 (en) 2006-03-02

Family

ID=34972186

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2005/000593 WO2005120335A2 (en) 2004-06-07 2005-06-06 Assay apparatus comprising an implanted light source

Country Status (1)

Country Link
WO (1) WO2005120335A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11484206B2 (en) 2014-11-25 2022-11-01 Ent. Services Development Corporation Lp Implantable device for detecting light correlating to vessel
KR20160111063A (en) * 2015-03-16 2016-09-26 울산과학기술원 Measuring apparatus for In vivo bio material
NL2015582B1 (en) 2015-10-07 2017-05-02 N V Nederlandsche Apparatenfabriek Nedap Measuring apparatus and method for measuring physiological data from a mammal.

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348002A (en) * 1992-04-23 1994-09-20 Sirraya, Inc. Method and apparatus for material analysis
US5571152A (en) * 1995-05-26 1996-11-05 Light Sciences Limited Partnership Microminiature illuminator for administering photodynamic therapy
US5995860A (en) * 1995-07-06 1999-11-30 Thomas Jefferson University Implantable sensor and system for measurement and control of blood constituent levels
US6049727A (en) * 1996-07-08 2000-04-11 Animas Corporation Implantable sensor and system for in vivo measurement and control of fluid constituent levels
US20030114735A1 (en) * 2000-05-15 2003-06-19 Silver James H. Implantable, retrievable sensors and immunosensors
WO2003063699A1 (en) * 2002-01-25 2003-08-07 Sensys Medical, Inc. Indirect measurement of tissue analytes through tissue properties
US6622049B2 (en) * 2000-10-16 2003-09-16 Remon Medical Technologies Ltd. Miniature implantable illuminator for photodynamic therapy
WO2005063117A2 (en) * 2003-12-29 2005-07-14 Glucon Inc. Glucometer comprising an implantable light source

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348002A (en) * 1992-04-23 1994-09-20 Sirraya, Inc. Method and apparatus for material analysis
US5571152A (en) * 1995-05-26 1996-11-05 Light Sciences Limited Partnership Microminiature illuminator for administering photodynamic therapy
US5995860A (en) * 1995-07-06 1999-11-30 Thomas Jefferson University Implantable sensor and system for measurement and control of blood constituent levels
US6049727A (en) * 1996-07-08 2000-04-11 Animas Corporation Implantable sensor and system for in vivo measurement and control of fluid constituent levels
US20030114735A1 (en) * 2000-05-15 2003-06-19 Silver James H. Implantable, retrievable sensors and immunosensors
US6622049B2 (en) * 2000-10-16 2003-09-16 Remon Medical Technologies Ltd. Miniature implantable illuminator for photodynamic therapy
WO2003063699A1 (en) * 2002-01-25 2003-08-07 Sensys Medical, Inc. Indirect measurement of tissue analytes through tissue properties
WO2005063117A2 (en) * 2003-12-29 2005-07-14 Glucon Inc. Glucometer comprising an implantable light source

Also Published As

Publication number Publication date
WO2005120335A2 (en) 2005-12-22

Similar Documents

Publication Publication Date Title
WO2005063117A3 (en) Glucometer comprising an implantable light source
WO2004107971A3 (en) Wearable glucometer
JP5709368B2 (en) Biological information acquisition device
CN1771885B (en) Apparatus and method for measuring blood component using light trans-reflectance
JP5762118B2 (en) Light irradiation apparatus, control method therefor, and object information acquisition apparatus
WO2005012553A3 (en) Optical in vivo probe of analyte concentration within the sterile matrix under the human nail
US8326390B2 (en) Optical non-invasive blood monitoring system and method
US20070078312A1 (en) Method and system for non-invasive measurements in a human body
WO2003079892A3 (en) A non-invasive blood analyte measuring system and method utilizing optical absorption
JP2003510556A (en) Non-invasive sensor capable of determining optical parameters of a sample with multiple layers
EP1598003A3 (en) Optical device
WO2008067438A3 (en) System and method for photoacoustic guided diffuse optical imaging
WO2003005890A3 (en) Affinity biosensor for monitoring of biological process
GB0324872D0 (en) Ocular property measuring apparatus and method therefor
WO2006014868A3 (en) Portable vein locating device
SE0501078L (en) A device for analyzing a fluid flow
EP2633805B1 (en) Object information acquiring apparatus
JP4772408B2 (en) Optical biological information measurement system and coupling layer used for optical information measurement
CN103099640A (en) Acoustic wave acquiring apparatus
WO2004000112A3 (en) Method and apparatus for determining tissue viability
WO2005120335A3 (en) Assay apparatus comprising an implanted light source
PT931264E (en) DIAGNOSTIC METHOD OF ATEROSCLEROSIS
DK0931265T3 (en) Diagnostic method of atherosclerosis
WO2006097933A3 (en) Method for monitoring changes in blood glucose level
RU2633494C2 (en) Biosensor for non-invasive optical monitoring of biological tissues pathology

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

122 Ep: pct application non-entry in european phase