WO2005116655A3 - Natriuretic compounds, conjugates, and uses thereof - Google Patents
Natriuretic compounds, conjugates, and uses thereof Download PDFInfo
- Publication number
- WO2005116655A3 WO2005116655A3 PCT/US2005/019249 US2005019249W WO2005116655A3 WO 2005116655 A3 WO2005116655 A3 WO 2005116655A3 US 2005019249 W US2005019249 W US 2005019249W WO 2005116655 A3 WO2005116655 A3 WO 2005116655A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- conjugates
- compounds
- disclosed
- natriuretic
- modified
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002568363A CA2568363A1 (en) | 2004-05-26 | 2005-05-26 | Natriuretic compounds, conjugates, and uses thereof |
EP05780093A EP1776132A4 (en) | 2004-05-26 | 2005-05-26 | Natriuretic compounds, conjugates, and uses thereof |
AU2005248860A AU2005248860A1 (en) | 2004-05-26 | 2005-05-26 | Natriuretic compounds, conjugates, and uses thereof |
NZ552210A NZ552210A (en) | 2004-05-26 | 2005-05-26 | Natriuretic compounds, conjugates, and uses thereof |
MXPA06013810A MXPA06013810A (en) | 2004-05-26 | 2005-05-26 | Natriuretic compounds, conjugates, and uses thereof. |
BRPI0511588-4A BRPI0511588A (en) | 2004-05-26 | 2005-05-26 | natriuretic compounds and conjugates and their uses |
JP2007515532A JP2008500375A (en) | 2004-05-26 | 2005-05-26 | Natriuretic compounds, complexes, and uses thereof |
IL179521A IL179521A0 (en) | 2004-05-26 | 2006-11-23 | Natriuretic compounds, conjugates, and uses thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57443604P | 2004-05-26 | 2004-05-26 | |
US60/574,436 | 2004-05-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005116655A2 WO2005116655A2 (en) | 2005-12-08 |
WO2005116655A3 true WO2005116655A3 (en) | 2006-08-03 |
Family
ID=35451511
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/019249 WO2005116655A2 (en) | 2004-05-26 | 2005-05-26 | Natriuretic compounds, conjugates, and uses thereof |
Country Status (14)
Country | Link |
---|---|
US (3) | US7648962B2 (en) |
EP (1) | EP1776132A4 (en) |
JP (1) | JP2008500375A (en) |
KR (1) | KR20070050876A (en) |
CN (1) | CN101027073A (en) |
AU (1) | AU2005248860A1 (en) |
BR (1) | BRPI0511588A (en) |
CA (1) | CA2568363A1 (en) |
IL (1) | IL179521A0 (en) |
MX (1) | MXPA06013810A (en) |
NZ (1) | NZ552210A (en) |
RU (1) | RU2388765C2 (en) |
WO (1) | WO2005116655A2 (en) |
ZA (1) | ZA200610700B (en) |
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-
2004
- 2004-11-30 US US10/999,761 patent/US7648962B2/en not_active Expired - Fee Related
-
2005
- 2005-05-26 KR KR1020067027333A patent/KR20070050876A/en not_active Application Discontinuation
- 2005-05-26 RU RU2006145827/04A patent/RU2388765C2/en not_active IP Right Cessation
- 2005-05-26 CN CNA2005800252228A patent/CN101027073A/en active Pending
- 2005-05-26 US US11/138,194 patent/US20060074009A1/en not_active Abandoned
- 2005-05-26 CA CA002568363A patent/CA2568363A1/en not_active Abandoned
- 2005-05-26 BR BRPI0511588-4A patent/BRPI0511588A/en not_active IP Right Cessation
- 2005-05-26 MX MXPA06013810A patent/MXPA06013810A/en unknown
- 2005-05-26 EP EP05780093A patent/EP1776132A4/en not_active Withdrawn
- 2005-05-26 AU AU2005248860A patent/AU2005248860A1/en not_active Abandoned
- 2005-05-26 NZ NZ552210A patent/NZ552210A/en unknown
- 2005-05-26 WO PCT/US2005/019249 patent/WO2005116655A2/en active Application Filing
- 2005-05-26 JP JP2007515532A patent/JP2008500375A/en active Pending
-
2006
- 2006-11-23 IL IL179521A patent/IL179521A0/en unknown
- 2006-12-19 ZA ZA200610700A patent/ZA200610700B/en unknown
-
2010
- 2010-01-19 US US12/689,342 patent/US20100216714A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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US20060063699A1 (en) * | 1998-03-09 | 2006-03-23 | Larsen Bjarne D | Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis |
US20030219734A1 (en) * | 2001-04-13 | 2003-11-27 | Biosite Incorporated | Polypeptides related to natriuretic peptides and methods of their identification and use |
US6858580B2 (en) * | 2001-06-04 | 2005-02-22 | Nobex Corporation | Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
Also Published As
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IL179521A0 (en) | 2007-07-04 |
EP1776132A4 (en) | 2009-07-01 |
US20060172933A1 (en) | 2006-08-03 |
MXPA06013810A (en) | 2007-07-25 |
KR20070050876A (en) | 2007-05-16 |
WO2005116655A2 (en) | 2005-12-08 |
ZA200610700B (en) | 2008-03-26 |
JP2008500375A (en) | 2008-01-10 |
EP1776132A2 (en) | 2007-04-25 |
CN101027073A (en) | 2007-08-29 |
AU2005248860A1 (en) | 2005-12-08 |
US7648962B2 (en) | 2010-01-19 |
CA2568363A1 (en) | 2005-12-08 |
BRPI0511588A (en) | 2008-01-02 |
RU2006145827A (en) | 2008-07-10 |
US20100216714A1 (en) | 2010-08-26 |
NZ552210A (en) | 2009-11-27 |
US20060074009A1 (en) | 2006-04-06 |
RU2388765C2 (en) | 2010-05-10 |
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