WO2005114298A3 - Optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers - Google Patents

Optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers Download PDF

Info

Publication number
WO2005114298A3
WO2005114298A3 PCT/US2005/017981 US2005017981W WO2005114298A3 WO 2005114298 A3 WO2005114298 A3 WO 2005114298A3 US 2005017981 W US2005017981 W US 2005017981W WO 2005114298 A3 WO2005114298 A3 WO 2005114298A3
Authority
WO
WIPO (PCT)
Prior art keywords
particle
mirror
chemical groups
plasmon resonance
optical sensor
Prior art date
Application number
PCT/US2005/017981
Other languages
French (fr)
Other versions
WO2005114298A2 (en
Inventor
Vladimir Poponin
Original Assignee
Vp Holding Llc
Vladimir Poponin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU2005246415A priority Critical patent/AU2005246415B8/en
Priority to KR1020067025919A priority patent/KR101168654B1/en
Priority to NZ551786A priority patent/NZ551786A/en
Priority to EP05753332A priority patent/EP1766458A4/en
Priority to JP2007527527A priority patent/JP4806411B2/en
Priority to MXPA06013440A priority patent/MXPA06013440A/en
Application filed by Vp Holding Llc, Vladimir Poponin filed Critical Vp Holding Llc
Priority to BRPI0511255-9A priority patent/BRPI0511255A/en
Priority to CN2005800162096A priority patent/CN1957245B/en
Priority to CA2566123A priority patent/CA2566123C/en
Publication of WO2005114298A2 publication Critical patent/WO2005114298A2/en
Publication of WO2005114298A3 publication Critical patent/WO2005114298A3/en
Priority to IL179292A priority patent/IL179292A/en

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/20—Filters
    • G02B5/204—Filters in which spectral selection is performed by means of a conductive grid or array, e.g. frequency selective surfaces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

An optical sensor and method are disclosed for use with a visible-light laser excitation beam (60) and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte (80) applied to the sensor. The sensor includes a substrate (10), a plasmon resonance mirror (20) formed on a sensor surface of the substrate (10), a plasmon resonance particle layer (40) disposed over the mirror (20), and an optically transparent dielectric layer (30) about 2-40 nm thick separating the mirror (20) and particle layer (40). The particle layer (40) has a periodic array of plasmon resonance particles with (i) a coating to binding analyte molecules (80), (ii) substantially uniform particle sizes and shapes in a range between 50-200 nm (ii) a particle-to-particle spacing less than the wavelength of the laser excitation beam. The device is capable of detecting single analyte molecules (80) with an amplification factor of up to 1012­ 1014.
PCT/US2005/017981 2004-05-19 2005-05-19 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers WO2005114298A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
KR1020067025919A KR101168654B1 (en) 2004-05-19 2005-05-19 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers
NZ551786A NZ551786A (en) 2004-05-19 2005-05-19 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by surface enhanced raman scattering
EP05753332A EP1766458A4 (en) 2004-05-19 2005-05-19 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers
JP2007527527A JP4806411B2 (en) 2004-05-19 2005-05-19 Optical sensor for use with a visible light laser excitation beam and a Raman spectroscopic detector and method for detecting chemical groups in an analyte
MXPA06013440A MXPA06013440A (en) 2004-05-19 2005-05-19 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers.
AU2005246415A AU2005246415B8 (en) 2004-05-19 2005-05-19 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by SERS
BRPI0511255-9A BRPI0511255A (en) 2004-05-19 2005-05-19 layered plasmon structure optical sensor for enhanced detection of chemical groups by sers
CN2005800162096A CN1957245B (en) 2004-05-19 2005-05-19 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by SERS
CA2566123A CA2566123C (en) 2004-05-19 2005-05-19 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers
IL179292A IL179292A (en) 2004-05-19 2006-11-15 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57295904P 2004-05-19 2004-05-19
US60/572,959 2004-05-19

Publications (2)

Publication Number Publication Date
WO2005114298A2 WO2005114298A2 (en) 2005-12-01
WO2005114298A3 true WO2005114298A3 (en) 2006-10-12

Family

ID=35429016

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/017981 WO2005114298A2 (en) 2004-05-19 2005-05-19 Optical sensor with layered plasmon structure for enhanced detection of chemical groups by sers

Country Status (14)

Country Link
US (4) US7351588B2 (en)
EP (1) EP1766458A4 (en)
JP (1) JP4806411B2 (en)
KR (1) KR101168654B1 (en)
CN (1) CN1957245B (en)
AU (1) AU2005246415B8 (en)
BR (1) BRPI0511255A (en)
CA (1) CA2566123C (en)
IL (1) IL179292A (en)
MX (1) MXPA06013440A (en)
NZ (1) NZ551786A (en)
RU (1) RU2361193C2 (en)
WO (1) WO2005114298A2 (en)
ZA (1) ZA200610693B (en)

Families Citing this family (249)

* Cited by examiner, † Cited by third party
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IL179292A0 (en) 2007-03-08
CN1957245B (en) 2010-12-08
RU2006144957A (en) 2008-06-27
US20100248379A1 (en) 2010-09-30
AU2005246415A1 (en) 2005-12-01
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US20080198376A1 (en) 2008-08-21
CN1957245A (en) 2007-05-02

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