WO2005081970A3 - Self-assembling cell aggregates and methods of making engineered tissue using the same - Google Patents
Self-assembling cell aggregates and methods of making engineered tissue using the same Download PDFInfo
- Publication number
- WO2005081970A3 WO2005081970A3 PCT/US2005/005735 US2005005735W WO2005081970A3 WO 2005081970 A3 WO2005081970 A3 WO 2005081970A3 US 2005005735 W US2005005735 W US 2005005735W WO 2005081970 A3 WO2005081970 A3 WO 2005081970A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cell aggregates
- cell
- pellet
- matrix
- tissue
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000011159 matrix material Substances 0.000 abstract 3
- 210000000056 organ Anatomy 0.000 abstract 3
- 239000008188 pellet Substances 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 239000006285 cell suspension Substances 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0062—General methods for three-dimensional culture
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
- B29C64/10—Processes of additive manufacturing
- B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
- B29C64/112—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
- B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
- B29C64/205—Means for applying layers
- B29C64/209—Heads; Nozzles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
- B29C64/30—Auxiliary operations or equipment
- B29C64/386—Data acquisition or data processing for additive manufacturing
- B29C64/393—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y10/00—Processes of additive manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y50/00—Data acquisition or data processing for additive manufacturing
- B33Y50/02—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y70/00—Materials specially adapted for additive manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/12—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by pressure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2033/00—Use of polymers of unsaturated acids or derivatives thereof as moulding material
- B29K2033/26—Polymers of acrylamide or methacrylamide
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0058—Liquid or visquous
- B29K2105/0061—Gel or sol
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/7532—Artificial members, protheses
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/590,446 US8241905B2 (en) | 2004-02-24 | 2005-02-24 | Self-assembling cell aggregates and methods of making engineered tissue using the same |
US13/529,172 US8852932B2 (en) | 2004-02-24 | 2012-06-21 | Self-assembling cell aggregates and methods of making engineered tissue using the same |
US14/477,148 US20150004273A1 (en) | 2004-02-24 | 2014-09-04 | Apparatus for making engineered tissue using self-assembling cell aggregates |
US14/827,152 US20150344828A1 (en) | 2004-02-24 | 2015-08-14 | Self-assembling cell aggregates and methods of making engineered tissue using the same |
US14/995,583 US20160130551A1 (en) | 2004-02-24 | 2016-01-14 | Apparatus for making engineered tissue using self-assembling cell aggregates |
US15/235,422 US9752116B2 (en) | 2004-02-24 | 2016-08-12 | Self-assembling cell aggregates and methods of making engineered tissue using the same |
US15/424,123 US20170145386A1 (en) | 2004-02-24 | 2017-02-03 | Self-assembling cell aggregates and methods of making engineered tissue using the same |
US16/720,443 US20200140808A1 (en) | 2004-02-24 | 2019-12-19 | Self-assembling cell aggregates and methods of making engineered tissue using the same |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54716104P | 2004-02-24 | 2004-02-24 | |
US60/547,161 | 2004-02-24 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/590,446 A-371-Of-International US8241905B2 (en) | 2004-02-24 | 2005-02-24 | Self-assembling cell aggregates and methods of making engineered tissue using the same |
US13/529,172 Continuation US8852932B2 (en) | 2004-02-24 | 2012-06-21 | Self-assembling cell aggregates and methods of making engineered tissue using the same |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005081970A2 WO2005081970A2 (en) | 2005-09-09 |
WO2005081970A3 true WO2005081970A3 (en) | 2009-04-02 |
Family
ID=34910864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/005735 WO2005081970A2 (en) | 2004-02-24 | 2005-02-24 | Self-assembling cell aggregates and methods of making engineered tissue using the same |
Country Status (2)
Country | Link |
---|---|
US (8) | US8241905B2 (en) |
WO (1) | WO2005081970A2 (en) |
Families Citing this family (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6262229B1 (en) * | 1996-12-04 | 2001-07-17 | Biomeasure Incorporated | Somatostatin antagonists |
US20100330143A1 (en) | 2003-12-04 | 2010-12-30 | University Of Utah Research Foundation | Modified macromolecules and methods of making and using thereof |
US8241905B2 (en) | 2004-02-24 | 2012-08-14 | The Curators Of The University Of Missouri | Self-assembling cell aggregates and methods of making engineered tissue using the same |
US7718351B2 (en) | 2006-03-14 | 2010-05-18 | Agency For Science, Technology & Research | Three-dimensional fabrication of biocompatible structures in anatomical shapes and dimensions for tissue engineering and organ replacement |
US20090208466A1 (en) * | 2006-04-21 | 2009-08-20 | James Yoo | Ink-jet printing of tissues |
FR2901143B1 (en) * | 2006-05-16 | 2008-10-03 | Centre Nat Rech Scient | "METHOD OF CONSTRUCTING FUNCTIONAL LIVING MATERIALS, MATERIALS OBTAINED AND APPLICATIONS" |
US20070269476A1 (en) | 2006-05-16 | 2007-11-22 | Voytik-Harbin Sherry L | Engineered extracellular matrices control stem cell behavior |
KR101612049B1 (en) * | 2008-06-24 | 2016-04-14 | 더 큐레이터스 오브 더 유니버시티 오브 미주리 | Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same |
US8545857B2 (en) * | 2008-10-31 | 2013-10-01 | The Invention Science Fund I, Llc | Compositions and methods for administering compartmentalized frozen particles |
US8603494B2 (en) * | 2008-10-31 | 2013-12-10 | The Invention Science Fund I, Llc | Compositions and methods for administering compartmentalized frozen particles |
US9060931B2 (en) * | 2008-10-31 | 2015-06-23 | The Invention Science Fund I, Llc | Compositions and methods for delivery of frozen particle adhesives |
US9056047B2 (en) | 2008-10-31 | 2015-06-16 | The Invention Science Fund I, Llc | Compositions and methods for delivery of frozen particle adhesives |
US8731842B2 (en) * | 2008-10-31 | 2014-05-20 | The Invention Science Fund I, Llc | Compositions and methods for biological remodeling with frozen particle compositions |
US8603495B2 (en) * | 2008-10-31 | 2013-12-10 | The Invention Science Fund I, Llc | Compositions and methods for biological remodeling with frozen particle compositions |
WO2010087912A1 (en) * | 2009-01-30 | 2010-08-05 | University Of Utah Research Foundation | Hydrogels crosslinked with gold nanoparticles and methods of making and using thereof |
US20120171768A1 (en) * | 2009-04-20 | 2012-07-05 | Purdue Research Foundation | Collagen-based matrices for vessel density and size regulation |
KR101812820B1 (en) * | 2010-01-08 | 2017-12-27 | 웨이크 포리스트 유니버시티 헬스 사이언시즈 | Delivery system |
US8747880B2 (en) | 2010-02-02 | 2014-06-10 | The Curators Of The University Of Missouri | Engineered biological nerve graft, fabrication and application thereof |
GB201004614D0 (en) * | 2010-03-19 | 2010-05-05 | Ge Healthcare Uk Ltd | A system and method for automated extraction of multi-cellular physiological parameters |
WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
AU2015202836B2 (en) * | 2010-10-21 | 2016-11-03 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue |
JP2013542728A (en) * | 2010-10-21 | 2013-11-28 | オルガノボ,インク. | Devices, systems, and methods for creating an organization |
WO2012122105A1 (en) | 2011-03-07 | 2012-09-13 | Wake Forest University Health Sciences | Delivery system |
KR20140050064A (en) * | 2011-07-26 | 2014-04-28 | 더 큐레이터스 오브 더 유니버시티 오브 미주리 | Engineered comestible meat |
JP2014526318A (en) * | 2011-09-12 | 2014-10-06 | オルガノボ,インク. | Platform for engineered implantable tissues and organs and method of manufacturing the same |
KR20140072883A (en) * | 2011-09-12 | 2014-06-13 | 오가노보, 인크. | Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same |
US9499779B2 (en) | 2012-04-20 | 2016-11-22 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking |
CA2878404A1 (en) | 2012-07-10 | 2014-01-16 | The Trustees Of The University Of Pennsylvania | Biomaterials for enhanced implant-host integration |
US20150246072A1 (en) * | 2012-09-04 | 2015-09-03 | Anthrogenesis Corporation | Methods of tissue generation |
KR20210043023A (en) * | 2012-09-04 | 2021-04-20 | 안트로제네시스 코포레이션 | Methods of tissue generation |
WO2014039938A1 (en) * | 2012-09-07 | 2014-03-13 | Modern Meadow, Inc. | Spherical multicellular aggregates with endogenous extracellular matrix |
US9442105B2 (en) | 2013-03-15 | 2016-09-13 | Organovo, Inc. | Engineered liver tissues, arrays thereof, and methods of making the same |
EP3670155A1 (en) | 2013-06-13 | 2020-06-24 | Aspect Biosystems Ltd. | System for additive manufacturing of three-dimensional structures and method for same |
CA2919734C (en) | 2013-07-31 | 2023-04-25 | Organovo, Inc. | Automated devices, systems, and methods for the fabrication of tissue |
WO2015038988A1 (en) | 2013-09-13 | 2015-03-19 | Modern Meadow, Inc. | Edible and animal-product-free microcarriers for engineered meat |
ITTO20130822A1 (en) * | 2013-10-10 | 2015-04-11 | Fond Istituto Italiano Di Tecnologia | SYSTEM FOR MANUFACTURING A SCAFFOLD FOR CELL CULTURE INCLUDING A PNEUMATIC PARTICLE TRANSFER AND RELATED SCAFFOLD |
ES2907145T3 (en) | 2013-10-11 | 2022-04-22 | Advanced Solutions Life Sciences Llc | System and workstation for the design, fabrication and assembly of biomaterial constructs |
US9878071B2 (en) | 2013-10-16 | 2018-01-30 | Purdue Research Foundation | Collagen compositions and methods of use |
US20160297104A1 (en) | 2013-11-19 | 2016-10-13 | Guill Tool & Engineering | Coextruded, multilayer and multicomponent 3d printing inputs field |
CA2938156C (en) | 2014-02-05 | 2022-05-10 | Modern Meadow, Inc. | Dried food products formed from cultured muscle cells |
CA2939270A1 (en) * | 2014-02-11 | 2015-08-20 | Structur3D Printing Incorporated | Multi-material extruder and extrusion method for three-dimensional (3d) printing |
CA3177480A1 (en) | 2014-04-04 | 2015-10-08 | Organovo, Inc. | Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model |
US9764515B2 (en) | 2014-05-01 | 2017-09-19 | Musc Foundation For Research Development | Multidispensor cartesian robotic printer |
JP6817194B2 (en) * | 2014-05-12 | 2021-01-20 | ルースタービオ インコーポレイテッド | Instantly printable cells and integrated devices |
SG10201801654RA (en) | 2014-05-28 | 2018-04-27 | Childrens Hospital Med Ct | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
EP2949350B1 (en) | 2014-05-29 | 2022-05-11 | Sabanci Üniversitesi | Artificial hollow biological tissue network and method for preparation thereof |
US9481868B2 (en) | 2014-10-06 | 2016-11-01 | Organovo, Inc. | Engineered renal tissues, arrays thereof, and methods of making the same |
EP3207123A1 (en) | 2014-10-17 | 2017-08-23 | Children's Hospital Center D/b/a Cincinnati Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
JP2017537654A (en) | 2014-11-05 | 2017-12-21 | オルガノボ インコーポレイテッド | Artificial three-dimensional skin tissue, array thereof, and manufacturing method thereof |
EP3018531B1 (en) | 2014-11-10 | 2020-07-29 | Technische Universität Berlin | Method and device for creating a three-dimensional multi-cell object |
WO2016172365A1 (en) | 2015-04-21 | 2016-10-27 | Purdue Research Foundation Office Of Technology Commercialization | Cell-collagen-silica composites and methods of making and using the same |
CN104985822B (en) * | 2015-07-15 | 2017-03-08 | 佛山市南海区广工大数控装备协同创新研究院 | 3D cell printing system and its Method of printing |
WO2017033958A1 (en) * | 2015-08-24 | 2017-03-02 | Necソリューションイノベータ株式会社 | Cell ink, cell ink production container, cell ink production kit, cell ink production method, ink cartridge, sterically formed object production method, and sterically formed object |
ES2878120T3 (en) | 2015-08-31 | 2021-11-18 | Cellink Ab | Cleanroom technology for bioprinters and 3D printers |
JP2018529334A (en) * | 2015-09-04 | 2018-10-11 | ザ ジェネラル ホスピタル コーポレイション | 3D micro tissue bio printer |
EP3337923B2 (en) | 2015-09-21 | 2023-01-04 | Modern Meadow, Inc. | Fiber reinforced tissue composites |
US11338065B2 (en) | 2015-10-08 | 2022-05-24 | Massachusetts Institute Of Technology | In situ expansion of engineered devices for regeneration |
NZ741377A (en) | 2015-10-09 | 2022-02-25 | Deka Products Lp | Fluid pumping and bioreactor system |
CN108349155B (en) | 2015-10-20 | 2021-07-09 | 惠普发展公司,有限责任合伙企业 | Systems, methods, and computer-readable media for patterned layer deposition |
TWI593547B (en) | 2015-11-13 | 2017-08-01 | 財團法人工業技術研究院 | Three dimensional tissue printing device, three dimensional tissue printing method and artifical skin |
BR112017016266A2 (en) | 2016-02-15 | 2018-03-27 | Modern Meadow, Inc. | method for producing a biofabricated material. |
WO2017192997A1 (en) | 2016-05-05 | 2017-11-09 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
US11254901B2 (en) | 2016-07-12 | 2022-02-22 | Deka Products Limited Partnership | System and method for printing tissue |
US10345208B2 (en) | 2016-07-12 | 2019-07-09 | Deka Products Limited Partnership | System and method for applying force to a device |
DK3514227T3 (en) | 2016-09-13 | 2020-09-14 | Jiro Ono | PROCEDURE FOR MANUFACTURE OF THREE-DIMENSIONAL CELL STRUCTURE AND SUPPORT USED FOR THE SAME |
DK3519558T3 (en) | 2016-09-28 | 2023-11-13 | Organovo Inc | USE OF MODIFIED KIDNEY TISSUE IN ASSAYS |
US11299705B2 (en) | 2016-11-07 | 2022-04-12 | Deka Products Limited Partnership | System and method for creating tissue |
EP3538169A4 (en) | 2016-11-10 | 2020-09-30 | Organovo, Inc. | Bioprinted hair follicles and uses thereof |
KR20190076023A (en) | 2016-11-10 | 2019-07-01 | 오가노보, 인크. | Engineered intestinal tissue and uses thereof |
US10308057B2 (en) * | 2016-12-02 | 2019-06-04 | Canon Finetech Nisca Inc. | Transfer material, printed material, and manufacturing method for printed material |
SG10202105768WA (en) | 2016-12-05 | 2021-06-29 | Childrens Hospital Med Ct | Colonic organoids and methods of making and using same |
US20180200791A1 (en) * | 2017-01-13 | 2018-07-19 | General Electric Company | Dynamically damped recoater |
FR3063930B1 (en) * | 2017-03-15 | 2019-03-22 | Poietis | BIOIMPRESSION PROCESS |
SG11201908329QA (en) | 2017-03-15 | 2019-10-30 | Aspect Biosystems Ltd | Systems and methods for printing a fiber structure |
WO2018200750A1 (en) | 2017-04-25 | 2018-11-01 | Purdue Research Foundation | 3-dimensional (3d) tissue-engineered muscle for tissue restoration |
EP3427949A1 (en) | 2017-07-12 | 2019-01-16 | Albert-Ludwigs-Universität Freiburg | Mechanically tunable bioinks for bioprinting |
US10570362B2 (en) | 2017-07-12 | 2020-02-25 | Deka Products Limited Partnership | System and method for transferring tissue |
WO2019079424A1 (en) | 2017-10-20 | 2019-04-25 | Indiana University Research And Technology Corporation | Scaffold-free 3d bioprinting of porcine cells |
AU2018253595A1 (en) | 2017-11-13 | 2019-05-30 | Modern Meadow, Inc. | Biofabricated leather articles having zonal properties |
WO2019180776A1 (en) | 2018-03-19 | 2019-09-26 | ティシューバイネット株式会社 | Production device, production system and production method for cell structure |
RU2701330C1 (en) * | 2018-11-28 | 2019-09-25 | Частное учреждение Лаборатория биотехнологических исследований "3Д Биопринтинг Солюшенс" (ЧУ"3Д Биопринтинг Солюшенс") | Device for biopressing by single fabric spheroids and used in it a printing head |
EP3704202A4 (en) | 2019-01-17 | 2020-12-16 | Modern Meadow, Inc. | Layered collagen materials and methods of making the same |
WO2021087354A1 (en) * | 2019-10-30 | 2021-05-06 | The General Hospital Corporation | High-throughput culture of ipsc-derived alveolar cells |
US20220064603A1 (en) * | 2020-08-31 | 2022-03-03 | Regents Of The University Of Minnesota | Alignment of cells in engineered tissues |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001068811A2 (en) * | 2000-03-13 | 2001-09-20 | Co.Don Aktiengesellschaft | Method for in vitro production of three-dimensional vital cartilage or bone tissue and use thereof as transplant material |
US6979670B1 (en) * | 1999-03-10 | 2005-12-27 | Biora Bioex Ab | Matrix protein compositions for grafting |
Family Cites Families (118)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4759764A (en) | 1985-05-24 | 1988-07-26 | Clayton Foundation For Research | Peripheral nerve regeneration |
US4808435A (en) | 1987-04-06 | 1989-02-28 | International Business Machines Corporation | Screen printing method for producing lines of uniform width and height |
US5099090A (en) | 1988-05-11 | 1992-03-24 | Ariel Electronics, Inc. | Circuit writer |
US5596251A (en) * | 1995-06-07 | 1997-01-21 | Alcoa Closure Systems International, Inc. | Servo motor-driven plastic cutter system for compression molding |
EP1019492A1 (en) | 1997-07-03 | 2000-07-19 | Massachusetts Institute Of Technology | Tissue-engineered constructs |
US6401795B1 (en) | 1997-10-28 | 2002-06-11 | Sandia Corporation | Method for freeforming objects with low-binder slurry |
EP1084454B1 (en) | 1998-04-21 | 2016-03-09 | University of Connecticut | Free-form nanofabrication using multi-photon excitation |
US6697694B2 (en) | 1998-08-26 | 2004-02-24 | Electronic Materials, L.L.C. | Apparatus and method for creating flexible circuits |
US7338798B2 (en) | 1998-09-15 | 2008-03-04 | The Regents Of The University Of Michigan | System and method for forming a cardiac muscle construct |
EP1029692B9 (en) | 1999-02-17 | 2003-12-03 | Hewlett-Packard Company, A Delaware Corporation | Printing apparatus |
US6642243B1 (en) | 1999-07-22 | 2003-11-04 | Ashkan Imanzahrai | Migraine medicine and method for treating same |
JP2001145956A (en) | 1999-11-19 | 2001-05-29 | Meiko:Kk | Apparatus and method for laminate shaping of photosetting resin three-dimensional shaped article |
US6503273B1 (en) | 1999-11-22 | 2003-01-07 | Cyograft Tissue Engineering, Inc. | Tissue engineered blood vessels and methods and apparatus for their manufacture |
US6454972B1 (en) | 1999-11-24 | 2002-09-24 | Sandia Corporation | Solid freeform fabrication using chemically reactive suspensions |
US6520997B1 (en) | 1999-12-08 | 2003-02-18 | Baxter International Inc. | Porous three dimensional structure |
US6315469B1 (en) | 2000-01-19 | 2001-11-13 | Hewlett-Packard Company | Tool and method for adjustment of printhead to platen spacing in a printer |
US20050091576A1 (en) | 2003-10-24 | 2005-04-28 | Microsoft Corporation | Programming interface for a computer platform |
DE10018987A1 (en) | 2000-04-17 | 2001-10-31 | Envision Technologies Gmbh | Device and method for producing three-dimensional objects |
WO2002004113A2 (en) * | 2000-07-11 | 2002-01-17 | The Johns Hopkins University School Of Medicine | Methods of patterning protein and cell adhesivity |
US7998735B2 (en) | 2000-08-21 | 2011-08-16 | Victorian Tissue Engineering Centre Pty. Ltd. | Vascularized tissue graft |
US6561607B1 (en) | 2000-10-05 | 2003-05-13 | Eastman Kodak Company | Apparatus and method for maintaining a substantially constant closely spaced working distance between an inkjet printhead and a printing receiver |
US20020129485A1 (en) * | 2001-03-13 | 2002-09-19 | Milling Systems And Concepts Pte Ltd | Method and apparatus for producing a prototype |
US6939489B2 (en) | 2001-03-23 | 2005-09-06 | Ivoclar Vivadent Ag | Desktop process for producing dental products by means of 3-dimensional plotting |
AU2002305201A1 (en) | 2001-04-19 | 2002-11-05 | Case Western Reserve University | Fabrication of a polymeric prosthetic implant |
DE10127225A1 (en) | 2001-05-22 | 2002-11-28 | Zeiss Carl | Ultraviolet light cut filter |
CN1798832B (en) | 2001-07-26 | 2010-04-28 | 片冈一则 | Cultured cell construct containing spheroids of cultured animal cells and utilization thereof |
US20030049839A1 (en) | 2001-08-01 | 2003-03-13 | The University Of Texas System | Transparent multi-channel cell scaffold that creates a cellular and/or molecular gradient |
US6986739B2 (en) | 2001-08-23 | 2006-01-17 | Sciperio, Inc. | Architecture tool and methods of use |
US6934600B2 (en) | 2002-03-14 | 2005-08-23 | Auburn University | Nanotube fiber reinforced composite materials and method of producing fiber reinforced composites |
US20100254900A1 (en) | 2002-03-18 | 2010-10-07 | Campbell Phil G | Biocompatible polymers and Methods of use |
US20030175410A1 (en) | 2002-03-18 | 2003-09-18 | Campbell Phil G. | Method and apparatus for preparing biomimetic scaffold |
US6907307B2 (en) | 2002-07-02 | 2005-06-14 | 3D Systems, Inc. | Support volume calculation for a CAD model |
WO2004006840A2 (en) | 2002-07-12 | 2004-01-22 | The Regents Of The University Of California | Three dimensional cell patterned bioploymer scaffolds and method of making the same |
US6998264B2 (en) | 2002-11-19 | 2006-02-14 | Huntington Medical Research Institutes | Replication of biological tissue |
US20050238746A1 (en) * | 2002-12-31 | 2005-10-27 | E.I. Dupont De Nemours & Company | Apparatus, system and method for making hydrogel particles |
US7641898B2 (en) * | 2003-03-21 | 2010-01-05 | Materials Evolution And Development Usa, Inc. | Keratinocyte-fibrocyte concomitant grafting for wound healing |
US20040197375A1 (en) | 2003-04-02 | 2004-10-07 | Alireza Rezania | Composite scaffolds seeded with mammalian cells |
US7051654B2 (en) * | 2003-05-30 | 2006-05-30 | Clemson University | Ink-jet printing of viable cells |
CA2528134C (en) | 2003-06-04 | 2015-05-12 | University Of South Carolina | Tissue scaffold having aligned fibrils, apparatus and method for producing the same, and artificial tissue and methods of use thereof |
JP4474858B2 (en) | 2003-07-07 | 2010-06-09 | セイコーエプソン株式会社 | GAP ADJUSTMENT DEVICE, CALIBRATION JIG USED FOR THE SAME, DROPLET DISCHARGE DEVICE EQUIPPED WITH GAP ADJUSTMENT DEVICE, AND ELECTRO-OPTICAL DEVICE MANUFACTURING METHOD |
US20050074877A1 (en) | 2003-07-28 | 2005-04-07 | Mao Jeremy Jian | Biological engineering of articular structures containing both cartilage and bone |
FR2859128B1 (en) | 2003-08-29 | 2006-03-10 | Centre Nat Rech Scient | METHOD AND DEVICE FOR MANUFACTURING A THREE DIMENSIONAL MULTIMATERIAL COMPONENT BY INKJET TYPE PRINTING |
US8043614B2 (en) | 2004-03-09 | 2011-10-25 | Ahlfors Jan-Eric W | Autogenic living scaffolds and living tissue matrices: methods and uses thereof |
DE10353281A1 (en) | 2003-11-14 | 2005-06-16 | Bayer Cropscience Ag | Combination of active ingredients with insecticidal and acaricidal properties |
US20050276791A1 (en) * | 2004-02-20 | 2005-12-15 | The Ohio State University | Multi-layer polymer scaffolds |
US8241905B2 (en) | 2004-02-24 | 2012-08-14 | The Curators Of The University Of Missouri | Self-assembling cell aggregates and methods of making engineered tissue using the same |
US20090142307A1 (en) | 2004-07-09 | 2009-06-04 | Athanasiou Kyriacos A | Shape-Based Approach for Scaffoldless Tissue Engineering |
US7939003B2 (en) | 2004-08-11 | 2011-05-10 | Cornell Research Foundation, Inc. | Modular fabrication systems and methods |
US7651665B2 (en) | 2004-09-07 | 2010-01-26 | Hewlett-Packard Development Company, L.P. | Microtray for handling biosubstances |
US7767446B2 (en) | 2004-09-16 | 2010-08-03 | Becton, Dickinson And Company | Perfusion bioreactors for culturing cells |
KR100606457B1 (en) | 2004-11-11 | 2006-11-23 | 한국기계연구원 | Three-dimensional printing prototyping system |
JP4539316B2 (en) | 2004-12-08 | 2010-09-08 | セイコーエプソン株式会社 | Head position correction method, head position correction apparatus, droplet discharge apparatus, and electro-optical device manufacturing method |
US7568904B2 (en) | 2005-03-03 | 2009-08-04 | Laser Solutions Co., Ltd. | Stereolithography apparatus |
JP4729948B2 (en) | 2005-03-09 | 2011-07-20 | ブラザー工業株式会社 | Liquid supply apparatus and ink jet recording apparatus provided with the liquid supply apparatus |
US7780897B2 (en) | 2005-04-22 | 2010-08-24 | Board Of Regents, The University Of Texas System | Hydrogel constructs using stereolithography |
EP2495310A3 (en) | 2005-05-24 | 2013-03-27 | The Regents Of the University of California | Microscale micropatterned engineered in vitro tissue |
EP2093256A3 (en) | 2005-07-28 | 2009-10-14 | Carnegie Mellon University | Biocompatible polymers and methods of use |
US8690957B2 (en) | 2005-12-21 | 2014-04-08 | Warsaw Orthopedic, Inc. | Bone graft composition, method and implant |
US20070200276A1 (en) | 2006-02-24 | 2007-08-30 | Micron Technology, Inc. | Method for rapid printing of near-field and imprint lithographic features |
US7680555B2 (en) | 2006-04-03 | 2010-03-16 | Stratasys, Inc. | Auto tip calibration in an extrusion apparatus |
US20070231787A1 (en) * | 2006-04-04 | 2007-10-04 | Voelker Mark A | Methods and devices for imaging and manipulating biological samples |
EP2007875A4 (en) | 2006-04-05 | 2009-12-16 | Univ Rice William M | Dermis-derived cells for tissue engineering applications |
WO2007124481A2 (en) | 2006-04-21 | 2007-11-01 | Drexel University | Bioprinting three-dimensional structures onto microscale tissue analog devices for pharmacokinetic study and other uses |
US20090208466A1 (en) | 2006-04-21 | 2009-08-20 | James Yoo | Ink-jet printing of tissues |
JP4051077B2 (en) | 2006-04-28 | 2008-02-20 | シャープ株式会社 | Droplet applicator, gap measurement method for droplet discharge unit, and gap adjustment method for droplet discharge unit |
FR2901143B1 (en) | 2006-05-16 | 2008-10-03 | Centre Nat Rech Scient | "METHOD OF CONSTRUCTING FUNCTIONAL LIVING MATERIALS, MATERIALS OBTAINED AND APPLICATIONS" |
US7959942B2 (en) | 2006-10-20 | 2011-06-14 | Orbusneich Medical, Inc. | Bioabsorbable medical device with coating |
DE102006053121B3 (en) | 2006-11-10 | 2007-12-27 | Eos Gmbh Electro Optical Systems | Coating device for applying powdered layers to a device for producing a three-dimensional object comprises longitudinal walls joined together, a unit for fluidizing powdered material and a controlling and/or regulating unit |
US8764828B2 (en) | 2007-02-02 | 2014-07-01 | The Regents Of The University Of Michigan | System and method for forming bone, ligament, and bone-ligament constructs |
US8343740B2 (en) | 2007-03-29 | 2013-01-01 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Micro-organ device |
EP2586428B1 (en) * | 2007-04-26 | 2023-11-08 | Sublimity Therapeutics Limited | Manufacture of multiple minicapsules |
WO2008153968A2 (en) | 2007-06-07 | 2008-12-18 | Wake Forest University Health Sciences | Inkjet gene printing |
EP2664443B1 (en) | 2007-07-25 | 2021-08-25 | Stratasys Ltd. | Solid freeform fabrication using a plurality of modeling materials |
ATE530274T1 (en) | 2007-08-29 | 2011-11-15 | Vito Nv | METHOD FOR PRODUCING A THREE-DIMENSIONAL MACROPOROUS FILAMENT CONSTRUCTION BASED ON PHASE INVERSION AND THE CONSTRUCTION OBTAINED THEREFROM |
US20090076531A1 (en) | 2007-09-18 | 2009-03-19 | Richardson Charles L | Method and apparatus for bypass graft |
WO2009051701A2 (en) | 2007-10-15 | 2009-04-23 | Wake Forest University Health Sciences | Methods and compositions for printing biologically compatible nanotube composites of autologous tissue |
US7923846B2 (en) | 2007-11-16 | 2011-04-12 | Stats Chippac Ltd. | Integrated circuit package-in-package system with wire-in-film encapsulant |
EP2090584A1 (en) | 2008-02-13 | 2009-08-19 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Identification of a novel cysteine-rich cell penetrating peptide |
KR100922232B1 (en) | 2008-02-13 | 2009-10-16 | 연세대학교 산학협력단 | Method for Direct Patterning of live Cells using Electrohydrodynamic Printing Method and Device therefor |
WO2009102484A2 (en) | 2008-02-14 | 2009-08-20 | Wake Forest University Health Sciences | Inkjet printing of tissues and cells |
US20090248145A1 (en) * | 2008-03-28 | 2009-10-01 | Nanyang Technological University | Method of forming a three-dimensional structure of unidirectionally aligned cells |
US8876513B2 (en) | 2008-04-25 | 2014-11-04 | 3D Systems, Inc. | Selective deposition modeling using CW UV LED curing |
US9303245B2 (en) | 2008-06-20 | 2016-04-05 | Universiteit Maastricht | Self-assembling tissue modules |
KR101612049B1 (en) | 2008-06-24 | 2016-04-14 | 더 큐레이터스 오브 더 유니버시티 오브 미주리 | Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same |
US9097702B2 (en) | 2008-07-29 | 2015-08-04 | Cornell University | Pathologically relevant tumor microenvironments for high-throughput drug screening |
WO2010030964A2 (en) | 2008-09-12 | 2010-03-18 | The Brigham And Women's Hospital, Inc. | 3-dimensional multi-layered hydrogels and methods of making the same |
WO2010060080A1 (en) | 2008-11-24 | 2010-05-27 | Immunotrex Corporation | Three dimensional tissue generation |
EP2450707B1 (en) | 2010-11-04 | 2016-04-27 | University of Pécs | Lung tissue model |
WO2011038373A2 (en) | 2009-09-28 | 2011-03-31 | Virginia Tech Intellectual Properties, Inc. | Three-dimensional bioprinting of biosynthetic cellulose (bc) implants and scaffolds for tissue engineering |
US8409603B2 (en) | 2009-10-01 | 2013-04-02 | University Of South Carolina | Compositions and methods for tissue engineering, tissue regeneration and wound healing |
US20110177590A1 (en) | 2009-12-11 | 2011-07-21 | Drexel University | Bioprinted Nanoparticles and Methods of Use |
KR101812820B1 (en) | 2010-01-08 | 2017-12-27 | 웨이크 포리스트 유니버시티 헬스 사이언시즈 | Delivery system |
EP2523656A4 (en) | 2010-01-15 | 2013-12-11 | Univ Utah Res Found | Crosslinked hydrogels and methods of making and using thereof |
US8747880B2 (en) | 2010-02-02 | 2014-06-10 | The Curators Of The University Of Missouri | Engineered biological nerve graft, fabrication and application thereof |
JP5757961B2 (en) | 2010-03-04 | 2015-08-05 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | Bioprinting station, assembly including the bioprinting station, and bioprinting method |
GB2478801B (en) | 2010-03-16 | 2012-05-30 | Organovo Inc | Multilayered vascular tubes |
EP2552406B1 (en) | 2010-03-26 | 2018-01-24 | Stemmatters, Biotecnologia e Medicina Regenerativa, S.A. | Photo-crosslinked gellan gum-based hydrogels: preparation methods and uses thereof |
US9592255B2 (en) | 2010-07-01 | 2017-03-14 | The Regents Of The University Of Michigan | Scaffold-free three dimensional nerve fibroblast constructs |
US20120089238A1 (en) | 2010-10-06 | 2012-04-12 | Hyun-Wook Kang | Integrated organ and tissue printing methods, system and apparatus |
JP2013542728A (en) | 2010-10-21 | 2013-11-28 | オルガノボ,インク. | Devices, systems, and methods for creating an organization |
JP5283747B2 (en) | 2011-02-09 | 2013-09-04 | 富士フイルム株式会社 | Colored radiation-sensitive composition, color filter, manufacturing method thereof, solid-state imaging device, and liquid crystal display device |
DE202011003443U1 (en) | 2011-03-02 | 2011-12-23 | Bego Medical Gmbh | Device for the generative production of three-dimensional components |
WO2012122105A1 (en) | 2011-03-07 | 2012-09-13 | Wake Forest University Health Sciences | Delivery system |
GB201105226D0 (en) | 2011-03-29 | 2011-05-11 | Univ Leiden | Methods |
JP5599356B2 (en) | 2011-03-31 | 2014-10-01 | 富士フイルム株式会社 | A simulation method, a program, a recording medium on which the program is recorded, a method of creating a droplet arrangement pattern using the program, a nanoimprint method, a method of manufacturing a patterned substrate, and an inkjet apparatus. |
JP2014526318A (en) | 2011-09-12 | 2014-10-06 | オルガノボ,インク. | Platform for engineered implantable tissues and organs and method of manufacturing the same |
KR20140072883A (en) | 2011-09-12 | 2014-06-13 | 오가노보, 인크. | Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same |
US10059056B2 (en) | 2012-02-01 | 2018-08-28 | Nscrypt, Inc. | Micro-dispensing multi-layered 3D objects with curing steps |
WO2013130823A1 (en) | 2012-02-29 | 2013-09-06 | Massachusetts Institute Of Technology | Inverse patterning process for three-dimensional multi-compartmental micro-organization of multiple cell types |
EP2822612A4 (en) | 2012-03-06 | 2015-08-12 | Uab Research Foundation | Three-dimesional, prevascularized, engineered tissue constructs, methods of making and methods of using the tissue constructs |
US9499779B2 (en) | 2012-04-20 | 2016-11-22 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking |
US20140099709A1 (en) | 2012-06-19 | 2014-04-10 | Organovo, Inc. | Engineered three-dimensional connective tissue constructs and methods of making the same |
US9421716B2 (en) | 2012-08-08 | 2016-08-23 | Makerbot Industries, Llc | Photo booth for three-dimensional images |
US9442105B2 (en) | 2013-03-15 | 2016-09-13 | Organovo, Inc. | Engineered liver tissues, arrays thereof, and methods of making the same |
JP2016522312A (en) | 2013-03-15 | 2016-07-28 | マターファブ, コーポレイションMatterfab Corp. | Cartridge for additive manufacturing apparatus and method |
US9802360B2 (en) | 2013-06-04 | 2017-10-31 | Stratsys, Inc. | Platen planarizing process for additive manufacturing system |
CA2919734C (en) | 2013-07-31 | 2023-04-25 | Organovo, Inc. | Automated devices, systems, and methods for the fabrication of tissue |
CA3177480A1 (en) | 2014-04-04 | 2015-10-08 | Organovo, Inc. | Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model |
-
2005
- 2005-02-24 US US10/590,446 patent/US8241905B2/en active Active
- 2005-02-24 WO PCT/US2005/005735 patent/WO2005081970A2/en active Application Filing
-
2012
- 2012-06-21 US US13/529,172 patent/US8852932B2/en active Active
-
2014
- 2014-09-04 US US14/477,148 patent/US20150004273A1/en not_active Abandoned
-
2015
- 2015-08-14 US US14/827,152 patent/US20150344828A1/en not_active Abandoned
-
2016
- 2016-01-14 US US14/995,583 patent/US20160130551A1/en not_active Abandoned
- 2016-08-12 US US15/235,422 patent/US9752116B2/en active Active
-
2017
- 2017-02-03 US US15/424,123 patent/US20170145386A1/en not_active Abandoned
-
2019
- 2019-12-19 US US16/720,443 patent/US20200140808A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6979670B1 (en) * | 1999-03-10 | 2005-12-27 | Biora Bioex Ab | Matrix protein compositions for grafting |
WO2001068811A2 (en) * | 2000-03-13 | 2001-09-20 | Co.Don Aktiengesellschaft | Method for in vitro production of three-dimensional vital cartilage or bone tissue and use thereof as transplant material |
US20030153078A1 (en) * | 2000-03-13 | 2003-08-14 | Jeanette Libera | Method for in vitro production of three-dimensional vital cartilage or bone tissue and use thereof as transplant material |
Non-Patent Citations (1)
Title |
---|
KOIBUCHI, N. ET AL.: "Behavior of Cells in Artificially MAde Cell Aggregates and Tissue Fragments after Grafting to Debveloping Hind Limb Buds in Xenophus laevis.", INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY., vol. 43, pages 141 - 148 * |
Also Published As
Publication number | Publication date |
---|---|
US20200140808A1 (en) | 2020-05-07 |
US8241905B2 (en) | 2012-08-14 |
WO2005081970A2 (en) | 2005-09-09 |
US8852932B2 (en) | 2014-10-07 |
US20160348067A1 (en) | 2016-12-01 |
US20160130551A1 (en) | 2016-05-12 |
US9752116B2 (en) | 2017-09-05 |
US20170145386A1 (en) | 2017-05-25 |
US20120288938A1 (en) | 2012-11-15 |
US20080070304A1 (en) | 2008-03-20 |
US20150004273A1 (en) | 2015-01-01 |
US20150344828A1 (en) | 2015-12-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2005081970A3 (en) | Self-assembling cell aggregates and methods of making engineered tissue using the same | |
WO2005079383A3 (en) | Biodegradable netting | |
CN101687347B (en) | Method of preparing a molded article | |
DE502005004099D1 (en) | POWDER FOR RAPID PROTOTYPING AND METHOD FOR THE PRODUCTION THEREOF | |
WO2002042056A8 (en) | Generative method for producing a part and device for carrying out this method | |
ATE461024T1 (en) | HIGH SPEED MANUFACTURING USING SHAPE MEMORY POLYMER COMPOSITES | |
DE602005024804D1 (en) | POLYMER STRUCTURES AND METHOD FOR THE PRODUCTION THEREOF | |
ATE240204T1 (en) | RAPID PROTOTYPING METHOD AND APPARATUS | |
US20230193577A1 (en) | Geogrid made from a coextruded multilayered polymer | |
WO2005080475A3 (en) | Use of core-shell particles for producing inverse-opal structures | |
JP2007519034A5 (en) | ||
DE50108543D1 (en) | ABSORBENT STRUCTURE AND METHOD FOR THE PRODUCTION THEREOF | |
ES2189486T3 (en) | METHOD FOR FILLING AND REINFORCING SANDWICH PANELS OF BEE NEST. | |
Kumar et al. | Evaluation in 4D printing–a review | |
DE102013007800B4 (en) | Dry mortar plate and method and use of a device for its production | |
PL1658324T3 (en) | Thermochromic polymer layer and method for producing said layer | |
DE502007005290D1 (en) | METHOD FOR PRODUCING A VULCANIZATION FORM OF COMPOSIBLE PROFILE SEGMENTS AND VULCANIZATION FORM | |
KR101849948B1 (en) | Biocompatible polymer scaffold with structure for enhanced mechanical strength and manufacturing method of the same | |
WO2006017845A3 (en) | High aspect ratio template and method for producing same | |
KR102026635B1 (en) | Scaffold and fabrication method by dragging technique | |
DK200501374A (en) | Moldable core material | |
WO2004082524A3 (en) | Composite injectable and pre-fabricated bone replacement material and method for the production of such bone replacement material | |
WO2009008363A1 (en) | (inorganic nanoparticle)-(cellulose gel) complex, and method for production thereof | |
WO2005028396A3 (en) | Use of core-shell particles | |
CN107053698A (en) | A kind of preparation method of the anti-layering foam core filled composite material plate material of pile |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
122 | Ep: pct application non-entry in european phase | ||
WWE | Wipo information: entry into national phase |
Ref document number: 10590446 Country of ref document: US |