WO2005079294A3 - Methods and apparatus for intraocular brachytherapy - Google Patents

Methods and apparatus for intraocular brachytherapy Download PDF

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Publication number
WO2005079294A3
WO2005079294A3 PCT/US2005/004391 US2005004391W WO2005079294A3 WO 2005079294 A3 WO2005079294 A3 WO 2005079294A3 US 2005004391 W US2005004391 W US 2005004391W WO 2005079294 A3 WO2005079294 A3 WO 2005079294A3
Authority
WO
WIPO (PCT)
Prior art keywords
radiation source
methods
cannula
intraocular brachytherapy
brachytherapy
Prior art date
Application number
PCT/US2005/004391
Other languages
French (fr)
Other versions
WO2005079294A2 (en
Inventor
Richard Hillstead
Charles Larsen
Roelof Trip
Rainer Pintaske
Sabine Behrmann
Eberhard Fritz
Juan Eugene De
Mark Humayun
Gerd T Phillipps
Original Assignee
Neo Vista Inc
Richard Hillstead
Charles Larsen
Roelof Trip
Rainer Pintaske
Sabine Behrmann
Eberhard Fritz
Juan Eugene De
Mark Humayun
Gerd T Phillipps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neo Vista Inc, Richard Hillstead, Charles Larsen, Roelof Trip, Rainer Pintaske, Sabine Behrmann, Eberhard Fritz, Juan Eugene De, Mark Humayun, Gerd T Phillipps filed Critical Neo Vista Inc
Priority to BRPI0507690-0A priority Critical patent/BRPI0507690A/en
Priority to AU2005214040A priority patent/AU2005214040B2/en
Priority to JP2006553269A priority patent/JP4602356B2/en
Priority to AT05722965T priority patent/ATE488269T1/en
Priority to CN2005800047488A priority patent/CN101005873B/en
Priority to EP05722965A priority patent/EP1720608B1/en
Priority to CA2554961A priority patent/CA2554961C/en
Priority to DE602005024771T priority patent/DE602005024771D1/en
Publication of WO2005079294A2 publication Critical patent/WO2005079294A2/en
Publication of WO2005079294A3 publication Critical patent/WO2005079294A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014Intracavitary radiation therapy
    • A61N5/1017Treatment of the eye, e.g. for "macular degeneration"

Abstract

A device (10) for performing intraocular brachytherapy is disclosed. The apparatus (10) preferably comprises a hand-held delivery device (14) that advances a radiation source (12) into an associated cannula or probe (18) that is positioned adjacent the target tissue. The handpiece (14) provides for shielded storage of the radiation source (12) when retracted from the cannula (18) and includes a slider mechanism (52) for advancing and retracting the radiation source (12). The radiation source (12) is mounted to a wire that has a flexible distal end and a relatively stiffer proximal end.
PCT/US2005/004391 2004-02-12 2005-02-11 Methods and apparatus for intraocular brachytherapy WO2005079294A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
BRPI0507690-0A BRPI0507690A (en) 2004-02-12 2005-02-11 methods and apparatus for intraocular brachytherapy
AU2005214040A AU2005214040B2 (en) 2004-02-12 2005-02-11 Methods and apparatus for intraocular brachytherapy
JP2006553269A JP4602356B2 (en) 2004-02-12 2005-02-11 Method and apparatus for intraocular brachytherapy
AT05722965T ATE488269T1 (en) 2004-02-12 2005-02-11 DEVICE FOR INTRAOCULAR BRACHYTHERAPY
CN2005800047488A CN101005873B (en) 2004-02-12 2005-02-11 Apparatus for intraocular brachytherapy
EP05722965A EP1720608B1 (en) 2004-02-12 2005-02-11 Apparatus for intraocular brachytherapy
CA2554961A CA2554961C (en) 2004-02-12 2005-02-11 Methods and apparatus for intraocular brachytherapy
DE602005024771T DE602005024771D1 (en) 2004-02-12 2005-02-11 DEVICE FOR INTRA-ECULAR BRACHYTHERAPY

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54400104P 2004-02-12 2004-02-12
US60/544,001 2004-02-12

Publications (2)

Publication Number Publication Date
WO2005079294A2 WO2005079294A2 (en) 2005-09-01
WO2005079294A3 true WO2005079294A3 (en) 2007-02-15

Family

ID=34885993

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2005/004390 WO2005079915A1 (en) 2004-02-12 2005-02-11 Methods and apparatus for intraocular brachytherapy
PCT/US2005/004391 WO2005079294A2 (en) 2004-02-12 2005-02-11 Methods and apparatus for intraocular brachytherapy

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2005/004390 WO2005079915A1 (en) 2004-02-12 2005-02-11 Methods and apparatus for intraocular brachytherapy

Country Status (10)

Country Link
US (4) US7744520B2 (en)
EP (2) EP2298412A1 (en)
JP (1) JP4602356B2 (en)
CN (1) CN101005873B (en)
AT (1) ATE488269T1 (en)
AU (1) AU2005214040B2 (en)
BR (1) BRPI0507690A (en)
CA (1) CA2554961C (en)
DE (1) DE602005024771D1 (en)
WO (2) WO2005079915A1 (en)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6875165B2 (en) 2001-02-22 2005-04-05 Retinalabs, Inc. Method of radiation delivery to the eye
US20060173232A1 (en) * 2003-06-18 2006-08-03 Lovoi Paul A HDR adapter for electronic radiation source applicator
AU2005214040B2 (en) 2004-02-12 2011-03-31 Neo Vista, Inc. Methods and apparatus for intraocular brachytherapy
US7563222B2 (en) * 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
CA2629648A1 (en) 2005-11-15 2007-05-24 Neovista Inc. Methods and apparatus for intraocular brachytherapy
US7620147B2 (en) 2006-12-13 2009-11-17 Oraya Therapeutics, Inc. Orthovoltage radiotherapy
US7535991B2 (en) 2006-10-16 2009-05-19 Oraya Therapeutics, Inc. Portable orthovoltage radiotherapy
US7831309B1 (en) 2006-12-06 2010-11-09 University Of Southern California Implants based on bipolar metal oxide semiconductor (MOS) electronics
US8506558B2 (en) 2008-01-11 2013-08-13 Oraya Therapeutics, Inc. System and method for performing an ocular irradiation procedure
US8363783B2 (en) 2007-06-04 2013-01-29 Oraya Therapeutics, Inc. Method and device for ocular alignment and coupling of ocular structures
US7801271B2 (en) 2007-12-23 2010-09-21 Oraya Therapeutics, Inc. Methods and devices for orthovoltage ocular radiotherapy and treatment planning
CN101951990A (en) 2007-12-23 2011-01-19 Oraya治疗公司 Methods and devices for detecting, controlling, and predicting radiation delivery
KR101725117B1 (en) * 2008-01-07 2017-04-10 살루타리스 메디컬 디바이스즈, 인코퍼레이티드 Devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye
US9873001B2 (en) 2008-01-07 2018-01-23 Salutaris Medical Devices, Inc. Methods and devices for minimally-invasive delivery of radiation to the eye
US8602959B1 (en) 2010-05-21 2013-12-10 Robert Park Methods and devices for delivery of radiation to the posterior portion of the eye
US8608632B1 (en) 2009-07-03 2013-12-17 Salutaris Medical Devices, Inc. Methods and devices for minimally-invasive extraocular delivery of radiation and/or pharmaceutics to the posterior portion of the eye
US9056201B1 (en) 2008-01-07 2015-06-16 Salutaris Medical Devices, Inc. Methods and devices for minimally-invasive delivery of radiation to the eye
US10022558B1 (en) 2008-01-07 2018-07-17 Salutaris Medical Devices, Inc. Methods and devices for minimally-invasive delivery of radiation to the eye
US20100152646A1 (en) * 2008-02-29 2010-06-17 Reshma Girijavallabhan Intravitreal injection device and method
EP2296756A1 (en) 2008-06-04 2011-03-23 Neovista, Inc. Handheld radiation delivery system for advancing a radiation source wire
WO2010008790A1 (en) * 2008-06-24 2010-01-21 Goshen Health System, Inc. Internal radiation shield for brachytherapy treatment
WO2010022153A1 (en) * 2008-08-20 2010-02-25 Neovista, Inc. Delivery device for intraocular brachytherapy
USD691267S1 (en) 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to eye
USD691269S1 (en) 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to an eye
USD691270S1 (en) 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to an eye
USD691268S1 (en) 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to eye
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
CA2757037C (en) 2009-01-29 2019-08-06 Forsight Vision4, Inc. Posterior segment drug delivery
US8663210B2 (en) 2009-05-13 2014-03-04 Novian Health, Inc. Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy
EP2496304A4 (en) * 2009-11-02 2013-04-17 Salutaris Medical Devices Inc Methods and devices for delivering appropriate minimally-invasive extraocular radiation
US8343106B2 (en) * 2009-12-23 2013-01-01 Alcon Research, Ltd. Ophthalmic valved trocar vent
BR112012017771B1 (en) * 2009-12-23 2020-07-14 Alcon Research, Llc VALVE TROCART CANNULA
US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
WO2011137162A1 (en) 2010-04-27 2011-11-03 Neovista, Inc. Radiotherapy delivery cannula with visual confirmation window
RS61601B1 (en) 2010-08-05 2021-04-29 Forsight Vision4 Inc Injector apparatus for drug delivery
AU2011285548B2 (en) 2010-08-05 2014-02-06 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
RS62540B1 (en) 2010-08-05 2021-12-31 Forsight Vision4 Inc Apparatus to treat an eye
US20120116381A1 (en) 2010-11-05 2012-05-10 Houser Kevin L Surgical instrument with charging station and wireless communication
US9072523B2 (en) 2010-11-05 2015-07-07 Ethicon Endo-Surgery, Inc. Medical device with feature for sterile acceptance of non-sterile reusable component
US9089338B2 (en) 2010-11-05 2015-07-28 Ethicon Endo-Surgery, Inc. Medical device packaging with window for insertion of reusable component
US20120116265A1 (en) 2010-11-05 2012-05-10 Houser Kevin L Surgical instrument with charging devices
US9011471B2 (en) 2010-11-05 2015-04-21 Ethicon Endo-Surgery, Inc. Surgical instrument with pivoting coupling to modular shaft and end effector
US10881448B2 (en) 2010-11-05 2021-01-05 Ethicon Llc Cam driven coupling between ultrasonic transducer and waveguide in surgical instrument
US9421062B2 (en) 2010-11-05 2016-08-23 Ethicon Endo-Surgery, Llc Surgical instrument shaft with resiliently biased coupling to handpiece
US9039720B2 (en) 2010-11-05 2015-05-26 Ethicon Endo-Surgery, Inc. Surgical instrument with ratcheting rotatable shaft
US9247986B2 (en) 2010-11-05 2016-02-02 Ethicon Endo-Surgery, Llc Surgical instrument with ultrasonic transducer having integral switches
US10660695B2 (en) 2010-11-05 2020-05-26 Ethicon Llc Sterile medical instrument charging device
US9000720B2 (en) 2010-11-05 2015-04-07 Ethicon Endo-Surgery, Inc. Medical device packaging with charging interface
US9017849B2 (en) 2010-11-05 2015-04-28 Ethicon Endo-Surgery, Inc. Power source management for medical device
US10085792B2 (en) 2010-11-05 2018-10-02 Ethicon Llc Surgical instrument with motorized attachment feature
US9649150B2 (en) 2010-11-05 2017-05-16 Ethicon Endo-Surgery, Llc Selective activation of electronic components in medical device
US9782215B2 (en) 2010-11-05 2017-10-10 Ethicon Endo-Surgery, Llc Surgical instrument with ultrasonic transducer having integral switches
US9161803B2 (en) * 2010-11-05 2015-10-20 Ethicon Endo-Surgery, Inc. Motor driven electrosurgical device with mechanical and electrical feedback
US9782214B2 (en) 2010-11-05 2017-10-10 Ethicon Llc Surgical instrument with sensor and powered control
US9510895B2 (en) 2010-11-05 2016-12-06 Ethicon Endo-Surgery, Llc Surgical instrument with modular shaft and end effector
US9597143B2 (en) 2010-11-05 2017-03-21 Ethicon Endo-Surgery, Llc Sterile medical instrument charging device
US9375255B2 (en) 2010-11-05 2016-06-28 Ethicon Endo-Surgery, Llc Surgical instrument handpiece with resiliently biased coupling to modular shaft and end effector
US10959769B2 (en) 2010-11-05 2021-03-30 Ethicon Llc Surgical instrument with slip ring assembly to power ultrasonic transducer
US9381058B2 (en) 2010-11-05 2016-07-05 Ethicon Endo-Surgery, Llc Recharge system for medical devices
US9526921B2 (en) 2010-11-05 2016-12-27 Ethicon Endo-Surgery, Llc User feedback through end effector of surgical instrument
US9017851B2 (en) 2010-11-05 2015-04-28 Ethicon Endo-Surgery, Inc. Sterile housing for non-sterile medical device component
CN101999980A (en) * 2010-11-17 2011-04-06 钱志春 Eye disease treatment rod and application method thereof
AU2011329656B2 (en) 2010-11-19 2017-01-05 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
JP4806731B1 (en) * 2011-02-26 2011-11-02 宏治 柴 Drainer
EP2712310A4 (en) * 2011-05-20 2014-12-10 Doheny Eye Inst Ocular ultrasound probe
EP2726016B1 (en) 2011-06-28 2023-07-19 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
WO2013011511A1 (en) 2011-07-18 2013-01-24 Mor Research Applications Ltd. A device for adjusting the intraocular pressure
WO2013040247A2 (en) 2011-09-16 2013-03-21 Forsight Vision4, Inc. Fluid exchange apparatus and methods
WO2013116061A1 (en) 2012-02-03 2013-08-08 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
KR101348727B1 (en) 2012-04-30 2014-01-16 (주)파티클라 Super miniature ionization beam tube for epithelial cancer brachytherapy
US9421311B2 (en) 2012-07-03 2016-08-23 Thoratec Corporation Motor assembly for catheter pump
EP4186557A1 (en) 2012-07-03 2023-05-31 Tc1 Llc Motor assembly for catheter pump
CA2905496A1 (en) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
AU2014241163B2 (en) 2013-03-28 2018-09-27 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
US20150105605A1 (en) * 2013-10-15 2015-04-16 Ip Liberty Vision Corporation Radioactive glass source in ophthalmic brachytherapy
EP3797742A1 (en) * 2014-02-12 2021-03-31 Gyroscope Therapeutics Limited Apparatus for suprachoroidal administration of therapeutic agent
CN104000624B (en) * 2014-04-24 2016-04-13 温州医科大学 A kind ofly be affixed on the ultrasonic probe of eye table for axis measurement
WO2016011191A1 (en) 2014-07-15 2016-01-21 Forsight Vision4, Inc. Ocular implant delivery device and method
SG11201700943TA (en) 2014-08-08 2017-03-30 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
US10136938B2 (en) 2014-10-29 2018-11-27 Ethicon Llc Electrosurgical instrument with sensor
CA2967330A1 (en) 2014-11-10 2016-05-19 Forsight Vision4, Inc. Expandable drug delivery devices and methods of use
CN105167909A (en) * 2015-10-20 2015-12-23 成都美创医疗科技股份有限公司 Low-temperature plasma ophthalmic scalpel bit
CN113069681B (en) 2015-11-20 2022-12-23 弗赛特影像4股份有限公司 Method of manufacturing a therapeutic device for sustained drug delivery
USD841164S1 (en) * 2015-12-16 2019-02-19 Novartis Ag Intraocular lens delivery device
KR101837593B1 (en) * 2015-12-30 2018-03-14 한국과학기술원 X-ray Brachytherapy System Using X-ray Tube Based on Carbon Nanotube for Keloid and Skin Cancer Treatment
ES2837524T3 (en) 2016-04-05 2021-06-30 Forsight Vision4 Inc Implantable ocular drug delivery devices
USD814638S1 (en) 2016-05-11 2018-04-03 Salutaris Medical Devices, Inc. Brachytherapy device
USD815285S1 (en) 2016-05-11 2018-04-10 Salutaris Medical Devices, Inc. Brachytherapy device
USD814637S1 (en) 2016-05-11 2018-04-03 Salutaris Medical Devices, Inc. Brachytherapy device
KR101794128B1 (en) 2016-07-01 2017-11-30 국립암센터 Apparatus for body- inserting having controllable radiation direction
US10376328B2 (en) * 2016-08-25 2019-08-13 Novartis Ag Surgical probe with an integrated motion sensor
USD808529S1 (en) 2016-08-31 2018-01-23 Salutaris Medical Devices, Inc. Holder for a brachytherapy device
USD808528S1 (en) 2016-08-31 2018-01-23 Salutaris Medical Devices, Inc. Holder for a brachytherapy device
GB201714392D0 (en) * 2017-09-07 2017-10-25 Marsteller Laurence Methods and devices for treating glaucoma
WO2021142298A1 (en) * 2020-01-08 2021-07-15 Radiance Therapeutics, Inc. Methods, systems, and compositions for maintaining functioning drainage blebs
CN111655206B (en) 2017-11-21 2022-10-14 弗赛特影像4股份有限公司 Fluid exchange device for expandable port delivery system and method of use
JP2022502160A (en) 2018-09-28 2022-01-11 ラディアンス セラピューティクス、インコーポレイテッド Methods, systems, and compositions for maintaining functioning drainage vesicles associated with minimally invasive microscleral incision.
USD933226S1 (en) 2018-11-29 2021-10-12 Radiance Therapeutics, Inc. Ophthalmic brachytherapy set
EP3886777A4 (en) 2018-11-29 2022-08-10 Radiance Therapeutics, Inc. Ophthalmic brachytherapy systems and devices for application of beta radiation
USD933225S1 (en) 2018-11-29 2021-10-12 Radiance Therapeutics, Inc. Ophthalmic brachytherapy device
US20230010712A1 (en) * 2019-12-06 2023-01-12 Radiance Therapeutics, Inc. Methods, systems, and compositions for achieving a healthy intraocular pressure following combined glaucoma filtration surgery and cataract extraction
CN117529350A (en) * 2021-06-30 2024-02-06 阿尔法陶医疗有限公司 Radiation therapy applicator with vertical or angled radial distribution

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637073A (en) * 1995-08-28 1997-06-10 Freire; Jorge E. Radiation therapy for treating macular degeneration and applicator
US6004279A (en) * 1996-01-16 1999-12-21 Boston Scientific Corporation Medical guidewire
US6676590B1 (en) * 1997-03-06 2004-01-13 Scimed Life Systems, Inc. Catheter system having tubular radiation source
US6875165B2 (en) * 2001-02-22 2005-04-05 Retinalabs, Inc. Method of radiation delivery to the eye

Family Cites Families (278)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US839061A (en) 1905-02-23 1906-12-18 Henri Farjas Apparatus for application of salts of radium.
US2517566A (en) 1946-07-29 1950-08-08 John E High Hose clamp
US2517568A (en) 1948-09-04 1950-08-08 Radium Chemical Company Inc Eye applicator
US2559793A (en) 1949-01-27 1951-07-10 Canadian Radium And Uranium Co Beta irradiation method and means
FR1585443A (en) 1968-07-23 1970-01-23
US6603988B2 (en) 2001-04-13 2003-08-05 Kelsey, Inc. Apparatus and method for delivering ablative laser energy and determining the volume of tumor mass destroyed
CA1102018A (en) * 1978-01-09 1981-05-26 Philip Mchugh Unitary self shielded, self filtered and flattened bremsstrahlung photon source assembly for radiotherapy use
US4584991A (en) * 1983-12-15 1986-04-29 Tokita Kenneth M Medical device for applying therapeutic radiation
US4662869A (en) * 1984-11-19 1987-05-05 Wright Kenneth W Precision intraocular apparatus
AU590872B2 (en) * 1985-02-26 1989-11-23 Johns Hopkins University, The Neovascularization inhibitors and methods for their production and use
US5322499A (en) 1985-09-20 1994-06-21 Liprie Sam F Continuous sheated low dose radioactive core adapted for cutting into short sealed segments
US5141487A (en) 1985-09-20 1992-08-25 Liprie Sam F Attachment of radioactive source and guidewire in a branchy therapy source wire
NL8601808A (en) * 1986-07-10 1988-02-01 Hooft Eric T METHOD FOR TREATING A BODY PART WITH RADIOACTIVE MATERIAL AND CART USED THEREIN
US4846172A (en) 1987-05-26 1989-07-11 Berlin Michael S Laser-delivery eye-treatment method
US4891165A (en) * 1988-07-28 1990-01-02 Best Industries, Inc. Device and method for encapsulating radioactive materials
US5084002A (en) 1988-08-04 1992-01-28 Omnitron International, Inc. Ultra-thin high dose iridium source for remote afterloader
DE3831141A1 (en) 1988-09-13 1990-03-22 Zeiss Carl Fa METHOD AND DEVICE FOR MICROSURGERY ON EYE BY LASER RADIATION
US5183455A (en) * 1988-10-07 1993-02-02 Omnitron International, Inc. Apparatus for in situ radiotherapy
US4861520A (en) 1988-10-28 1989-08-29 Eric van't Hooft Capsule for radioactive source
US4957476A (en) 1989-01-09 1990-09-18 University Of Pittsburgh Afterloading radioactive spiral implanter
US5147282A (en) 1989-05-04 1992-09-15 William Kan Irradiation loading apparatus
US4921327A (en) * 1989-05-24 1990-05-01 Zito Richard R Method of transmitting an ionizing radiation
SG49267A1 (en) 1989-08-14 1998-05-18 Photogenesis Inc Surgical instrument and cell isolation and transplantation
US5203353A (en) * 1989-10-24 1993-04-20 Surgical Technologies, Inc. Method of penetrating and working in the vitreous humor of the eye
US5199939B1 (en) * 1990-02-23 1998-08-18 Michael D Dake Radioactive catheter
US5267960A (en) 1990-03-19 1993-12-07 Omnitron International Inc. Tissue engaging catheter for a radioactive source wire
US5129895A (en) 1990-05-16 1992-07-14 Sunrise Technologies, Inc. Laser sclerostomy procedure
DE69119907T2 (en) 1990-07-13 1996-10-02 Mallinckrodt Medical Inc DEVICE FOR INSERTING A RADIOACTIVE SOURCE INTO THE BODY
US5342283A (en) 1990-08-13 1994-08-30 Good Roger R Endocurietherapy
US6099457A (en) 1990-08-13 2000-08-08 Endotech, Inc. Endocurietherapy
US5422926A (en) 1990-09-05 1995-06-06 Photoelectron Corporation X-ray source with shaped radiation pattern
US5282781A (en) * 1990-10-25 1994-02-01 Omnitron International Inc. Source wire for localized radiation treatment of tumors
US5160790A (en) * 1990-11-01 1992-11-03 C. R. Bard, Inc. Lubricious hydrogel coatings
US5354257A (en) 1991-01-29 1994-10-11 Med Institute, Inc. Minimally invasive medical device for providing a radiation treatment
US20010021382A1 (en) 1991-03-29 2001-09-13 Genentech, Inc. Vascular endothelial cell growth factor antagonists
US5257988A (en) 1991-07-19 1993-11-02 L'esperance Medical Technologies, Inc. Apparatus for phacoemulsifying cataractous-lens tissue within a protected environment
EP0634947B1 (en) * 1992-04-10 2001-12-19 Surgilight,Inc. Apparatus for performing eye surgery
CN1098186A (en) * 1993-03-29 1995-02-01 三洋电机株式会社 The control device of air conditioner
JPH09501326A (en) 1993-05-04 1997-02-10 オムニトロン インターナショナル インコーポレイテッド Radiation source wire, device using the same, and treatment method
DE69432148T2 (en) 1993-07-01 2003-10-16 Boston Scient Ltd CATHETER FOR IMAGE DISPLAY, DISPLAY OF ELECTRICAL SIGNALS AND ABLATION
EP0813894B1 (en) 1993-07-01 2001-12-05 Schneider (Europe) GmbH Medical appliances for the treatment of blood vessels by means of ionizing radiation
US5540659A (en) 1993-07-15 1996-07-30 Teirstein; Paul S. Irradiation catheter and method of use
US5445637A (en) * 1993-12-06 1995-08-29 American Cyanamid Company Method and apparatus for preventing posterior capsular opacification
US5707332A (en) * 1994-01-21 1998-01-13 The Trustees Of Columbia University In The City Of New York Apparatus and method to reduce restenosis after arterial intervention
US5503613A (en) * 1994-01-21 1996-04-02 The Trustees Of Columbia University In The City Of New York Apparatus and method to reduce restenosis after arterial intervention
US5425730A (en) 1994-02-16 1995-06-20 Luloh; K. P. Illumination cannula system for vitreous surgery
US5556389A (en) 1994-03-31 1996-09-17 Liprie; Samuel F. Method and apparatus for treating stenosis or other constriction in a bodily conduit
US5618266A (en) * 1994-03-31 1997-04-08 Liprie; Samuel F. Catheter for maneuvering radioactive source wire to site of treatment
US5426662A (en) 1994-04-28 1995-06-20 Coherent, Inc. Laser system selectively operable at two competing wavelengths
US5487725A (en) * 1994-05-12 1996-01-30 Syntec, Inc. Pneumatic vitrectomy for retinal attachment
US5503614A (en) * 1994-06-08 1996-04-02 Liprie; Samuel F. Flexible source wire for radiation treatment of diseases
US5857956A (en) * 1994-06-08 1999-01-12 United States Surgical Corporation Flexible source wire for localized internal irradiation of tissue
US5528651A (en) 1994-06-09 1996-06-18 Elekta Instrument Ab Positioning device and method for radiation treatment
ATE170708T1 (en) 1994-06-10 1998-09-15 Schneider Europ Gmbh MEDICINAL DEVICE FOR THE TREATMENT OF A PART OF BODY VESSEL USING IONIZATION RADIATION
EP0688580B1 (en) 1994-06-24 2000-10-04 Schneider (Europe) GmbH Medical appliance for the treatment of a portion of body vessel by ionising radiation
US5431907A (en) 1994-08-03 1995-07-11 Abelson; Mark B. Treatment of vascular disorders of the posterior segment of the eye by topical administration of calcium channel blocking agents
DE19535114B4 (en) 1994-09-21 2013-09-05 Hoya Corp. Endoscope system with fluorescence diagnosis
US6142994A (en) 1994-10-07 2000-11-07 Ep Technologies, Inc. Surgical method and apparatus for positioning a diagnostic a therapeutic element within the body
US5899882A (en) 1994-10-27 1999-05-04 Novoste Corporation Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient
US5683345A (en) 1994-10-27 1997-11-04 Novoste Corporation Method and apparatus for treating a desired area in the vascular system of a patient
US6059752A (en) * 1994-12-09 2000-05-09 Segal; Jerome Mechanical apparatus and method for dilating and irradiating a site of treatment
US5725493A (en) 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US5570408A (en) 1995-02-28 1996-10-29 X-Ray Optical Systems, Inc. High intensity, small diameter x-ray beam, capillary optic system
US5624437A (en) * 1995-03-28 1997-04-29 Freeman; Jerre M. High resolution, high speed, programmable laser beam modulating apparatus for microsurgery
US5596011A (en) * 1995-04-06 1997-01-21 Repine; Karen M. Method for the treatment of macular degeneration
US6041252A (en) * 1995-06-07 2000-03-21 Ichor Medical Systems Inc. Drug delivery system and method
ATE192346T1 (en) * 1995-06-22 2000-05-15 Schneider Europ Gmbh MEDICINAL DEVICE FOR THE TREATMENT OF A PART OF A BODY VESSEL USING IONIZATION RADIATION
US6377846B1 (en) * 1997-02-21 2002-04-23 Medtronic Ave, Inc. Device for delivering localized x-ray radiation and method of manufacture
US7338487B2 (en) 1995-08-24 2008-03-04 Medtronic Vascular, Inc. Device for delivering localized x-ray radiation and method of manufacture
EP0847249A4 (en) 1995-08-24 2004-09-29 Medtronic Ave Inc X-ray catheter
US5947958A (en) 1995-09-14 1999-09-07 Conceptus, Inc. Radiation-transmitting sheath and methods for its use
US5729583A (en) * 1995-09-29 1998-03-17 The United States Of America As Represented By The Secretary Of Commerce Miniature x-ray source
US5833593A (en) 1995-11-09 1998-11-10 United States Surgical Corporation Flexible source wire for localized internal irradiation of tissue
US5840008A (en) * 1995-11-13 1998-11-24 Localmed, Inc. Radiation emitting sleeve catheter and methods
US5713828A (en) 1995-11-27 1998-02-03 International Brachytherapy S.A Hollow-tube brachytherapy device
DE69530302T2 (en) 1995-12-05 2004-01-29 Schneider Europ Gmbh Buelach A filament for irradiating a living body and a method for producing a filament for irradiating a living body
AU1331497A (en) 1995-12-18 1997-07-14 Kerisma Medical Products, L.L.C. Fiberoptic-guided interstitial seed manual applicator and seed cartridge
US5651783A (en) 1995-12-20 1997-07-29 Reynard; Michael Fiber optic sleeve for surgical instruments
NL1002044C2 (en) 1996-01-08 1997-07-09 Optische Ind De Oude Delft Nv Radioactive source that has clinically relevant beta radiation
US6203524B1 (en) * 1997-02-10 2001-03-20 Emx, Inc. Surgical and pharmaceutical site access guide and methods
US5855546A (en) * 1996-02-29 1999-01-05 Sci-Med Life Systems Perfusion balloon and radioactive wire delivery system
US6234951B1 (en) 1996-02-29 2001-05-22 Scimed Life Systems, Inc. Intravascular radiation delivery system
US6059828A (en) * 1996-03-18 2000-05-09 Peyman; Gholam A. Macular indentor for use in the treatment of subretinal neovascular membranes
US5904144A (en) * 1996-03-22 1999-05-18 Cytotherapeutics, Inc. Method for treating ophthalmic diseases
US20020160970A1 (en) 1996-04-10 2002-10-31 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
KR20000065171A (en) 1996-05-01 2000-11-06 피터 지. 스트링거 Treatment of vascular endothelial growth factor-related diseases
US5797889A (en) 1996-06-19 1998-08-25 Becton Dickinson And Company Medical device having a connector portion with an improved surface finish
NL1003543C2 (en) * 1996-07-08 1998-01-12 Optische Ind Oede Oude Delftoe Brachytherapy capsule and brachytherapy capsule assembly and guide.
US5782740A (en) 1996-08-29 1998-07-21 Advanced Cardiovascular Systems, Inc. Radiation dose delivery catheter with reinforcing mandrel
US6120460A (en) 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
US5882291A (en) * 1996-12-10 1999-03-16 Neocardia, Llc Device and method for controlling dose rate during intravascular radiotherapy
US6287249B1 (en) * 1998-02-19 2001-09-11 Radiance Medical Systems, Inc. Thin film radiation source
US6458069B1 (en) 1998-02-19 2002-10-01 Endology, Inc. Multi layer radiation delivery balloon
US6491619B1 (en) 1997-01-31 2002-12-10 Endologix, Inc Radiation delivery catheters and dosimetry methods
US6134294A (en) 1998-02-13 2000-10-17 University Of Utah Research Foundation Device and method for precision macular X-irradiation
US5772642A (en) 1997-02-19 1998-06-30 Medtronic, Inc. Closed end catheter
DE69823406T2 (en) 1997-02-21 2005-01-13 Medtronic AVE, Inc., Santa Rosa X-ray device provided with a strain structure for local irradiation of the interior of a body
US5984853A (en) 1997-02-25 1999-11-16 Radi Medical Systems Ab Miniaturized source of ionizing radiation and method of delivering same
US20020172829A1 (en) 1997-02-28 2002-11-21 Yuichi Mori Coating composition, coating product and coating method
US6312374B1 (en) 1997-03-06 2001-11-06 Progenix, Llc Radioactive wire placement catheter
US5865720A (en) * 1997-03-06 1999-02-02 Scimed Life Systems, Inc. Expandable and retrievable radiation delivery system
US6059713A (en) * 1997-03-06 2000-05-09 Scimed Life Systems, Inc. Catheter system having tubular radiation source with movable guide wire
US6635008B1 (en) 1997-03-11 2003-10-21 Interventional Therapies Llc System and method for delivering a medical treatment to a treatment site
US5836882A (en) 1997-03-17 1998-11-17 Frazin; Leon J. Method and apparatus of localizing an insertion end of a probe within a biotic structure
AU6762198A (en) * 1997-03-18 1998-10-12 Focused X-Rays Llc Medical uses of focused and imaged x-rays
US6033357A (en) * 1997-03-28 2000-03-07 Navius Corporation Intravascular radiation delivery device
US6309339B1 (en) 1997-03-28 2001-10-30 Endosonics Corporation Intravascular radiation delivery device
US6135118A (en) * 1997-05-12 2000-10-24 Dailey; James P. Treatment with magnetic fluids
US6210312B1 (en) * 1997-05-20 2001-04-03 Advanced Cardiovascular Systems, Inc. Catheter and guide wire assembly for delivery of a radiation source
US6019718A (en) 1997-05-30 2000-02-01 Scimed Life Systems, Inc. Apparatus for intravascular radioactive treatment
US6106454A (en) 1997-06-17 2000-08-22 Medtronic, Inc. Medical device for delivering localized radiation
US6024690A (en) * 1997-07-01 2000-02-15 Endosonics Corporation Radiation source with delivery wire
US5913813A (en) 1997-07-24 1999-06-22 Proxima Therapeutics, Inc. Double-wall balloon catheter for treatment of proliferative tissue
US6482142B1 (en) 1997-07-24 2002-11-19 Proxima Therapeutics, Inc. Asymmetric radiation dosing apparatus and method
US5854822A (en) 1997-07-25 1998-12-29 Xrt Corp. Miniature x-ray device having cold cathode
EP1019145A1 (en) * 1997-09-23 2000-07-19 United States Surgical Corporation Source wire for radiation treatment
DE59708672D1 (en) 1997-09-26 2002-12-12 Schneider Europ Gmbh Buelach Balloon catheter inflated with carbon dioxide for radiotherapy
DE19744367C1 (en) 1997-10-08 1998-11-05 Schott Glas Simple application of thin, uniform silicone oil coating free from particles to medical cannula
US6030333A (en) * 1997-10-24 2000-02-29 Radiomed Corporation Implantable radiotherapy device
US6471630B1 (en) 1998-03-24 2002-10-29 Radiomed Corporation Transmutable radiotherapy device
US6419621B1 (en) 1997-10-24 2002-07-16 Radiomed Corporation Coiled brachytherapy device
AU743819B2 (en) 1997-10-27 2002-02-07 California Institute Of Technology Methods and pharmaceutical compositions for the closure of retinal breaks
US6273850B1 (en) 1997-10-29 2001-08-14 Medtronic Ave, Inc. Device for positioning a radiation source at a stenosis treatment site
IL122094A (en) 1997-11-03 2003-07-06 Israel Atomic Energy Comm In situ-generated solid radiation source based on tungsten<188>/rhenium<188> and the use thereof
WO1999024117A1 (en) 1997-11-07 1999-05-20 Global Vascular Concepts, Inc. Device for intravascular delivery of beta emitting isotopes
EP1035895A1 (en) 1997-12-05 2000-09-20 Cook Incorporated Medical radiation treatment device
US6213932B1 (en) * 1997-12-12 2001-04-10 Bruno Schmidt Interstitial brachytherapy device and method
US6561967B2 (en) 1997-12-12 2003-05-13 Bruno Schmidt Interstitial brachytherapy device and method
US5957829A (en) 1997-12-17 1999-09-28 Advanced Cardiovascular Systems, Inc. Apparatus and method for radiotherapy using a radioactive source wire having a magnetic insert
US6149574A (en) 1997-12-19 2000-11-21 Radiance Medical Systems, Inc. Dual catheter radiation delivery system
US6108402A (en) 1998-01-16 2000-08-22 Medtronic Ave, Inc. Diamond vacuum housing for miniature x-ray device
US6159140A (en) 1998-02-17 2000-12-12 Advanced Cardiovascular Systems Radiation shielded catheter for delivering a radioactive source and method of use
US6338709B1 (en) * 1998-02-19 2002-01-15 Medtronic Percusurge, Inc. Intravascular radiation therapy device and method of use
EP1064669A1 (en) 1998-03-06 2001-01-03 Medtronic AVE Inc. Method and x-ray device using adaptable power source
US6069938A (en) * 1998-03-06 2000-05-30 Chornenky; Victor Ivan Method and x-ray device using pulse high voltage source
US6496561B1 (en) * 1998-03-06 2002-12-17 Medtronic Ave, Inc. Devices, methods and systems for delivery of X-ray
US6036631A (en) * 1998-03-09 2000-03-14 Urologix, Inc. Device and method for intracavitary cancer treatment
US5928130A (en) 1998-03-16 1999-07-27 Schmidt; Bruno Apparatus and method for implanting radioactive seeds in tissue
US6293899B1 (en) 1998-03-24 2001-09-25 Radiomed Corporation Transmutable radiotherapy device
US6433012B1 (en) 1998-03-25 2002-08-13 Large Scale Biology Corp. Method for inhibiting inflammatory disease
US6099499A (en) 1998-04-28 2000-08-08 Medtronic, Inc. Device for in vivo radiation delivery and method for delivery
US6093142A (en) 1998-04-30 2000-07-25 Medtronic Inc. Device for in vivo radiation delivery and method for delivery
US6050930A (en) * 1998-06-02 2000-04-18 Teirstein; Paul S. Irradiation catheter with expandable source
US6053858A (en) * 1998-06-04 2000-04-25 Advanced Cardiovascular Systems, Inc. Radiation source
WO2000001410A1 (en) 1998-07-06 2000-01-13 Beth Israel Deaconess Medical Center Methods of inhibiting proliferative diseases by inhibiting tgf-beta mediated angiogenesis
US6164281A (en) 1998-07-20 2000-12-26 Zhao; Iris Ginron Method of making and/or treating diseases characterized by neovascularization
WO2000004953A2 (en) * 1998-07-20 2000-02-03 Cook Urological Inc. Brachytherapy device including an anti-static handle
US6378526B1 (en) * 1998-08-03 2002-04-30 Insite Vision, Incorporated Methods of ophthalmic administration
WO2000010643A1 (en) 1998-08-21 2000-03-02 Xrt Corp. Cathode structure with getter material and diamond film, and methods of manufacture thereof
US6391026B1 (en) 1998-09-18 2002-05-21 Pro Duct Health, Inc. Methods and systems for treating breast tissue
IL126341A0 (en) 1998-09-24 1999-05-09 Medirad I R T Ltd Radiation delivery devices and methods of making same
US6354989B1 (en) * 1998-10-14 2002-03-12 Terumo Kabushiki Kaisha Radiation source delivery wire and catheter assembly for radiation therapy provided with the same
JP2000116802A (en) * 1998-10-14 2000-04-25 Terumo Corp Catheter for radiotherapy and catheter assembly for radiotherapy
DE19850203C1 (en) 1998-10-23 2000-05-31 Eurotope Entwicklungsgesellsch Medical radioactive iodine-125 miniature source comprises a radioactive carrier matrix enclosed in a corrosion resistant and body-compatible material
US7312050B2 (en) 1998-10-29 2007-12-25 University Of Iowa Research Foundation Nucleic acids encoding interphotoreceptor matrix proteins
US6689043B1 (en) * 1998-11-06 2004-02-10 Amersham Plc Products and methods for brachytherapy
EP1127355B1 (en) 1998-11-06 2006-03-01 GE Healthcare Limited Products and methods for brachytherapy
WO2000030628A2 (en) 1998-11-20 2000-06-02 Genentech, Inc. Method of inhibiting angiogenesis
US6245047B1 (en) 1998-12-10 2001-06-12 Photoelectron Corporation X-Ray probe sheath apparatus
US6181770B1 (en) * 1998-12-11 2001-01-30 Photoelectron Corporation X-ray source interlock apparatus
US6111932A (en) * 1998-12-14 2000-08-29 Photoelectron Corporation Electron beam multistage accelerator
US6402676B2 (en) 1999-01-20 2002-06-11 Advanced Cardiovascular Systems, Inc. Tip configuration for radiation source wires
US6224536B1 (en) 1999-02-08 2001-05-01 Advanced Cardiovascular Systems Method for delivering radiation therapy to an intravascular site in a body
DE60019562D1 (en) * 1999-02-16 2005-05-25 Cordis Corp MANUAL SYSTEM FOR TRANSMITTING A TAPE FOR INTRAVASCULAR RADIOTHERAPY
US6196963B1 (en) * 1999-03-02 2001-03-06 Medtronic Ave, Inc. Brachytherapy device assembly and method of use
US6289079B1 (en) * 1999-03-23 2001-09-11 Medtronic Ave, Inc. X-ray device and deposition process for manufacture
DE19914914B4 (en) * 1999-04-01 2016-10-06 Carl Zeiss Meditec Ag Method and arrangement for the targeted application of a therapy beam, in particular for the treatment of diseased areas in the eye
US6183410B1 (en) * 1999-05-06 2001-02-06 Precision Vascular Systems, Inc. Radiation exposure device for blood vessels, body cavities and the like
US6195411B1 (en) 1999-05-13 2001-02-27 Photoelectron Corporation Miniature x-ray source with flexible probe
JP3685956B2 (en) 1999-06-11 2005-08-24 住友重機械工業株式会社 Eyeball irradiation control device
EP1060765B1 (en) 1999-06-18 2004-12-29 AEA Technology QSA GmbH Radiation source for endovascular radiation treatment
DE69930568T2 (en) 1999-06-18 2006-11-09 Aea Technology Qsa Gmbh Radiation source for endovascular irradiation
DE19933284A1 (en) 1999-07-15 2001-01-18 Friedrich Schiller Uni Jena Bu Solid body phantom for dosimetry of brachytherapy radiation sources in near field region has simple means for placing radiation source in solid body adjacent to radiation detector
US6551291B1 (en) * 1999-08-04 2003-04-22 Johns Hopkins University Non-traumatic infusion cannula and treatment methods using same
US6264599B1 (en) 1999-08-10 2001-07-24 Syntheon, Llc Radioactive therapeutic seeds having fixation structure
DE69915287T2 (en) 1999-09-20 2004-07-22 Aea Technology Qsa Gmbh Wire-shaped radiation source for endovascular radiation
US6582417B1 (en) 1999-09-22 2003-06-24 Advanced Cardiovascular Systems, Inc. Methods and apparatuses for radiation treatment
US6352501B1 (en) * 1999-09-23 2002-03-05 Scimed Life Systems, Inc. Adjustable radiation source
US6436026B1 (en) 1999-10-22 2002-08-20 Radiomed Corporation Flexible, continuous, axially elastic interstitial brachytherapy source
AU1374601A (en) 1999-11-12 2001-05-30 Angiotech International Ag Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors
US20030144570A1 (en) 1999-11-12 2003-07-31 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors
US6443976B1 (en) 1999-11-30 2002-09-03 Akorn, Inc. Methods for treating conditions and illnesses associated with abnormal vasculature
JP2001161838A (en) 1999-12-07 2001-06-19 Radiomed Corp Wire-like radiation source member for cancer treatment and feeding device of the same
US6450937B1 (en) 1999-12-17 2002-09-17 C. R. Bard, Inc. Needle for implanting brachytherapy seeds
WO2001049227A1 (en) * 2000-01-03 2001-07-12 Johns Hopkins University Surgical devices and methods of use thereof for enhanced tactile perception
EP1267935A2 (en) * 2000-01-12 2003-01-02 Light Sciences Corporation Novel treatment for eye disease
US6395294B1 (en) 2000-01-13 2002-05-28 Gholam A. Peyman Method of visualization of the vitreous during vitrectomy
US6575888B2 (en) 2000-01-25 2003-06-10 Biosurface Engineering Technologies, Inc. Bioabsorbable brachytherapy device
US7361643B2 (en) 2000-02-09 2008-04-22 University Of Puerto Rico Methods for inhibiting angiogenesis
ES2311507T3 (en) * 2000-02-10 2009-02-16 MASSACHUSETTS EYE &amp; EAR INFIRMARY PHOTODYNAMIC THERAPY FOR TREATMENT OF OPHTHALMIC AFFECTIONS.
US6285735B1 (en) 2000-02-11 2001-09-04 Photoelectron Corporation Apparatus for local radiation therapy
US6302581B1 (en) 2000-02-11 2001-10-16 Photoelectron Corporation Support system for a radiation treatment apparatus
US6301328B1 (en) 2000-02-11 2001-10-09 Photoelectron Corporation Apparatus for local radiation therapy
US6421416B1 (en) 2000-02-11 2002-07-16 Photoelectron Corporation Apparatus for local radiation therapy
US6320935B1 (en) 2000-02-28 2001-11-20 X-Technologies, Ltd. Dosimeter for a miniature energy transducer for emitting X-ray radiation
US6416457B1 (en) 2000-03-09 2002-07-09 Scimed Life Systems, Inc. System and method for intravascular ionizing tandem radiation therapy
US6755776B1 (en) 2000-03-20 2004-06-29 Louis Rogelio Granados Angioplasty radiation therapy to prevent restenosis
US6450938B1 (en) 2000-03-21 2002-09-17 Promex, Llc Brachytherapy device
US6984230B2 (en) * 2000-04-07 2006-01-10 Synergetics, Inc. Directional laser probe
US6659780B2 (en) * 2000-04-14 2003-12-09 Tronic Limited Underwater connector with electrical stress reduction
CA2407715C (en) * 2000-04-29 2009-03-24 University Of Iowa Research Foundation Diagnostics and therapeutics for macular degeneration-related disorders
WO2001085255A1 (en) 2000-05-09 2001-11-15 Radi Medical Technologies Ab Radiation therapy device with miniaturized radiation source
GB0011568D0 (en) 2000-05-15 2000-06-28 Nycomed Amersham Plc Grooved medical devices
GB0011581D0 (en) 2000-05-15 2000-07-05 Nycomed Amersham Plc Grooved brachytherapy
US6749553B2 (en) 2000-05-18 2004-06-15 Theragenics Corporation Radiation delivery devices and methods for their manufacture
US6443881B1 (en) * 2000-06-06 2002-09-03 Paul T. Finger Ophthalmic brachytherapy device
US6692759B1 (en) * 2000-06-28 2004-02-17 The Regents Of The University Of California Methods for preparing and using implantable substance delivery devices
US6458068B1 (en) 2000-07-21 2002-10-01 Real World Design And Development Company Apparatus for determining the position of radioactive seeds in needles used for radioactive seed therapy for prostate cancer
DE60135352D1 (en) * 2000-08-30 2008-09-25 Univ Johns Hopkins DEVICE FOR INTRA-OCCULAR ACTIVE AGGREGATION
EP1351946A2 (en) * 2000-09-01 2003-10-15 Icos Corporation Materials and methods to potentiate cancer treatment
CA2421251A1 (en) 2000-09-05 2002-03-14 Karolinska Innovations Ab Recombinant endothelial cell growth inhibitors derived from a mammalian plasminogen
US6714620B2 (en) * 2000-09-22 2004-03-30 Numerix, Llc Radiation therapy treatment method
US6530875B1 (en) * 2000-10-20 2003-03-11 Imagyn Medical Technologies, Inc. Brachytherapy seed deployment system
US6438206B1 (en) 2000-10-20 2002-08-20 X-Technologies, Ltd. Continuously pumped miniature X-ray emitting device and system for in-situ radiation treatment
WO2002038199A2 (en) 2000-11-08 2002-05-16 Theragenics Corporation Radioactive source wire and delivery catheter for brachytherapy
EP1205216A3 (en) 2000-11-09 2004-01-02 Radi Medical Technologies AB Miniature x-ray source insulation structure
EP1205217A3 (en) 2000-11-09 2004-01-02 Radi Medical Technologies AB Structure of miniature X-ray source
US6746661B2 (en) * 2000-11-16 2004-06-08 Microspherix Llc Brachytherapy seed
US6638205B1 (en) 2000-11-17 2003-10-28 Mds (Canada) Inc. Radioactive medical device for radiation therapy
DE10058163C2 (en) 2000-11-22 2003-07-10 Bebig Isotopen Und Medizintech Method and applicator for positioning and / or ejecting radiation sources via hollow needles into biological tissue
US20020110220A1 (en) 2000-11-22 2002-08-15 Zilan Shen Method and apparatus for delivering localized X-ray radiation to the interior of a body
US6866624B2 (en) * 2000-12-08 2005-03-15 Medtronic Ave,Inc. Apparatus and method for treatment of malignant tumors
US6415016B1 (en) 2001-01-09 2002-07-02 Medtronic Ave, Inc. Crystal quartz insulating shell for X-ray catheter
US6546077B2 (en) 2001-01-17 2003-04-08 Medtronic Ave, Inc. Miniature X-ray device and method of its manufacture
EP1357945A2 (en) 2001-02-06 2003-11-05 QLT Inc. Method to prevent vision loss
DE60100027T2 (en) * 2001-02-09 2003-04-30 Radi Medical Technologies Ab U Medical system with a miniaturized x-ray tube
EP1401480B1 (en) 2001-02-22 2012-11-28 Novartis AG Viral vectors encoding endostatin in the treatment of ocular neovascularization
US6497646B1 (en) 2001-03-14 2002-12-24 Cordis Corporation Intravascular radiotherapy source ribbon having variable radiopacity
US7244576B2 (en) 2001-04-18 2007-07-17 Rigel Pharmaceuticals, Inc. Modulators of angiogenesis
US7018371B2 (en) * 2001-05-07 2006-03-28 Xoft, Inc. Combination ionizing radiation and radiosensitizer delivery devices and methods for inhibiting hyperplasia
US20020169354A1 (en) * 2001-05-10 2002-11-14 Munro John J. Brachytherapy systems and methods
WO2002092162A2 (en) 2001-05-15 2002-11-21 University Of Stellenbosch Radiation application method and device
AU2002320088A1 (en) * 2001-06-13 2002-12-23 Marc G. Apple Brachytherapy device and method
US6771737B2 (en) 2001-07-12 2004-08-03 Medtronic Ave, Inc. X-ray catheter with miniature emitter and focusing cup
US6810109B2 (en) 2001-07-13 2004-10-26 Medtronic Ave, Inc. X-ray emitting system and method
US6497647B1 (en) 2001-07-18 2002-12-24 Ati Medical, Inc. Radiation and thermal energy source
US20060025800A1 (en) * 2001-09-05 2006-02-02 Mitta Suresh Method and device for surgical ventricular repair
US20030086903A1 (en) 2001-11-02 2003-05-08 Genvec, Inc. Therapeutic regimen for treating cancer
US6692481B2 (en) * 2001-12-13 2004-02-17 John M. Guerrero Method and apparatus for treatment of amblyopia
JP3993438B2 (en) * 2002-01-25 2007-10-17 株式会社ルネサステクノロジ Semiconductor device
JP2003265631A (en) * 2002-03-14 2003-09-24 Matsushita Electric Ind Co Ltd Conduit tube, balloon catheter using the same, therapeutic apparatus for arteriosclerosis, and therapeutic system
US6985557B2 (en) 2002-03-20 2006-01-10 Minnesota Medical Physics Llc X-ray apparatus with field emission current stabilization and method of providing x-ray radiation therapy
US6652442B2 (en) 2002-04-23 2003-11-25 Acueity, Inc. Micro-endoscope assembly for intraductal brachytherapy of a mammary duct and method of using same
NL1020740C2 (en) 2002-06-03 2003-12-08 Nucletron Bv Method and device for the temporary introduction and placement of at least one energy-emitting source in an animal body.
DE60324448D1 (en) 2002-09-10 2008-12-11 Cianna Medical Inc brachytherapy
US7041047B2 (en) 2002-10-04 2006-05-09 Boston Scientific Scimed, Inc. Method and apparatus for the delivery of brachytherapy
US8123698B2 (en) * 2002-10-07 2012-02-28 Suros Surgical Systems, Inc. System and method for minimally invasive disease therapy
US7070554B2 (en) 2003-01-15 2006-07-04 Theragenics Corporation Brachytherapy devices and methods of using them
US6953426B2 (en) 2003-01-29 2005-10-11 Mentor Corporation Seed magazine
US20040199130A1 (en) 2003-04-03 2004-10-07 Chornenky Victor I. Apparatus and method for treatment of macular degeneration
US20040218724A1 (en) 2003-04-30 2004-11-04 Chornenky Victor I. Miniature x-ray emitter
US20040218721A1 (en) 2003-04-30 2004-11-04 Chornenky Victor I. Miniature x-ray apparatus
US7273445B2 (en) * 2003-04-30 2007-09-25 Board Of Trustees Of The University Of Illinois Intraocular brachytherapy device and method
US6914960B2 (en) 2003-04-30 2005-07-05 Medtronic Vascular, Inc. Miniature x-ray emitter having independent current and voltage control
DE60311440T2 (en) * 2003-06-30 2007-08-23 Nucletron B.V. Miniature X-ray source
US20050049508A1 (en) * 2003-08-06 2005-03-03 Michael Forman Treatment of age-related macular degeneration
US8172770B2 (en) 2005-09-28 2012-05-08 Suros Surgical Systems, Inc. System and method for minimally invasive disease therapy
US7783006B2 (en) * 2003-10-10 2010-08-24 Xoft, Inc. Radiation treatment using x-ray source
DE60307288D1 (en) 2003-11-05 2006-09-14 Neovista Inc Radioactive source of radiation for ophthalmic brachytherapy
US7494457B2 (en) 2003-11-07 2009-02-24 Cytyc Corporation Brachytherapy apparatus and method for treating a target tissue through an external surface of the tissue
US7370284B2 (en) 2003-11-18 2008-05-06 Laszlo Systems, Inc. User interface for displaying multiple applications
AU2005214040B2 (en) 2004-02-12 2011-03-31 Neo Vista, Inc. Methods and apparatus for intraocular brachytherapy
US7563222B2 (en) 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
US7208748B2 (en) * 2004-07-21 2007-04-24 Still River Systems, Inc. Programmable particle scatterer for radiation therapy beam formation
US7425195B2 (en) 2004-08-13 2008-09-16 Core Oncology, Inc. Radiation shielding device
US20060084952A1 (en) * 2004-09-03 2006-04-20 Pallikaris Ioannis G Device for the irradiation of the ciliary body of the eye
US7662082B2 (en) 2004-11-05 2010-02-16 Theragenics Corporation Expandable brachytherapy device
US7223226B2 (en) 2004-11-05 2007-05-29 Nuclear Consultants Group, Inc. Brachytherapy needle and methods for assembling same
US8070767B2 (en) 2005-01-28 2011-12-06 Tyco Healthcare Group Lp Optical penetrating adapter for surgical portal
US7194063B2 (en) * 2005-02-10 2007-03-20 Brookhaven Science Associates, Llc Methods for implementing microbeam radiation therapy
US20060204535A1 (en) 2005-02-25 2006-09-14 Johnson Johnnie M Cell-friendly cannula and needle
US7618362B2 (en) 2005-03-28 2009-11-17 Boston Scientific Scimed, Inc. Spacer apparatus for radiation and ablation therapy
WO2007053823A2 (en) 2005-10-31 2007-05-10 Biolucent, Inc. Brachytherapy apparatus and methods of using same
US7862496B2 (en) 2005-11-10 2011-01-04 Cianna Medical, Inc. Brachytherapy apparatus and methods for using them
US7887476B2 (en) 2005-11-10 2011-02-15 Cianna Medical, Inc. Helical brachytherapy apparatus and methods of using same
CA2629648A1 (en) 2005-11-15 2007-05-24 Neovista Inc. Methods and apparatus for intraocular brachytherapy
DE102005056080B4 (en) 2005-11-24 2010-04-08 Siemens Ag Device for X-ray brachytherapy with a probe insertable into the interior of a body for X-ray brachytherapy
US8137256B2 (en) 2005-12-16 2012-03-20 Portola Medical, Inc. Brachytherapy apparatus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637073A (en) * 1995-08-28 1997-06-10 Freire; Jorge E. Radiation therapy for treating macular degeneration and applicator
US6004279A (en) * 1996-01-16 1999-12-21 Boston Scientific Corporation Medical guidewire
US6676590B1 (en) * 1997-03-06 2004-01-13 Scimed Life Systems, Inc. Catheter system having tubular radiation source
US6875165B2 (en) * 2001-02-22 2005-04-05 Retinalabs, Inc. Method of radiation delivery to the eye

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US7951060B2 (en) 2011-05-31
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US20050277802A1 (en) 2005-12-15
DE602005024771D1 (en) 2010-12-30
AU2005214040B2 (en) 2011-03-31
BRPI0507690A (en) 2007-07-24
JP4602356B2 (en) 2010-12-22
US20110004045A1 (en) 2011-01-06
CA2554961C (en) 2013-04-23
EP2298412A1 (en) 2011-03-23
JP2007526034A (en) 2007-09-13
CA2554961A1 (en) 2005-09-01
US20100268013A1 (en) 2010-10-21
US8365721B2 (en) 2013-02-05
US7744520B2 (en) 2010-06-29
CN101005873B (en) 2010-07-21
AU2005214040A1 (en) 2005-09-01
US7803102B2 (en) 2010-09-28
WO2005079294A2 (en) 2005-09-01
EP1720608B1 (en) 2010-11-17
WO2005079915A1 (en) 2005-09-01
US20070055089A1 (en) 2007-03-08
ATE488269T1 (en) 2010-12-15
CN101005873A (en) 2007-07-25

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