WO2005077320A3 - Method of increasing working time ttcp - Google Patents

Method of increasing working time ttcp Download PDF

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Publication number
WO2005077320A3
WO2005077320A3 PCT/US2005/004025 US2005004025W WO2005077320A3 WO 2005077320 A3 WO2005077320 A3 WO 2005077320A3 US 2005004025 W US2005004025 W US 2005004025W WO 2005077320 A3 WO2005077320 A3 WO 2005077320A3
Authority
WO
WIPO (PCT)
Prior art keywords
ttcp
calcium phosphate
working time
increasing working
whiskers
Prior art date
Application number
PCT/US2005/004025
Other languages
French (fr)
Other versions
WO2005077320A2 (en
Inventor
Jiin-Huey Chern Lin
Chien-Ping Ju
Wen-Cheng Chen
Kuan-Liang Lin
I-Chang Wang
Original Assignee
Calcitec Inc
Jiin-Huey Chern Lin
Chien-Ping Ju
Wen-Cheng Chen
Kuan-Liang Lin
I-Chang Wang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/773,701 external-priority patent/US7169373B2/en
Application filed by Calcitec Inc, Jiin-Huey Chern Lin, Chien-Ping Ju, Wen-Cheng Chen, Kuan-Liang Lin, I-Chang Wang filed Critical Calcitec Inc
Priority to EP05713163A priority Critical patent/EP1711155A2/en
Priority to CA002555240A priority patent/CA2555240A1/en
Publication of WO2005077320A2 publication Critical patent/WO2005077320A2/en
Publication of WO2005077320A3 publication Critical patent/WO2005077320A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/34—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders
    • C04B28/344—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders the phosphate binder being present in the starting composition solely as one or more phosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/864—Phosphate cements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B12/00—Cements not provided for in groups C04B7/00 - C04B11/00
    • C04B12/02—Phosphate cements
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/34—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders
    • C04B28/346—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders the phosphate binder being present in the starting composition as a mixture of free acid and one or more phosphates
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
    • C04B2111/00034—Physico-chemical characteristics of the mixtures
    • C04B2111/00086—Mixtures with prolonged pot-life
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
    • C04B2111/00474—Uses not provided for elsewhere in C04B2111/00
    • C04B2111/00836—Uses not provided for elsewhere in C04B2111/00 for medical or dental applications

Abstract

A tetracalcium phosphate (TTCP) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers on a surface thereof; the basic calcium phosphate whiskers having a Ca/P molar ratio greater than 1.33, and having a length up to about 5000 nm and a width up to about 500 nm. The basic calcium phosphate whiskers are substantially free of a hydroxyapatite phase and mainly composed of TTCP phase.
PCT/US2005/004025 2004-02-06 2005-02-07 Method of increasing working time ttcp WO2005077320A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP05713163A EP1711155A2 (en) 2004-02-06 2005-02-07 Method of increasing working time ttcp
CA002555240A CA2555240A1 (en) 2004-02-06 2005-02-07 Method of increasing working time ttcp

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/773,701 2004-02-06
US10/773,701 US7169373B2 (en) 1999-07-14 2004-02-06 Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface and process for preparing the same
US10/940,922 2004-09-14
US10/940,922 US7270705B2 (en) 1999-07-14 2004-09-14 Method of increasing working time of tetracalcium phosphate cement paste

Publications (2)

Publication Number Publication Date
WO2005077320A2 WO2005077320A2 (en) 2005-08-25
WO2005077320A3 true WO2005077320A3 (en) 2005-09-22

Family

ID=34864645

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/004025 WO2005077320A2 (en) 2004-02-06 2005-02-07 Method of increasing working time ttcp

Country Status (4)

Country Link
US (1) US7270705B2 (en)
EP (1) EP1711155A2 (en)
CA (1) CA2555240A1 (en)
WO (1) WO2005077320A2 (en)

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US6840995B2 (en) * 1999-07-14 2005-01-11 Calcitec, Inc. Process for producing fast-setting, bioresorbable calcium phosphate cements
US6960249B2 (en) * 1999-07-14 2005-11-01 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface
US7094282B2 (en) * 2000-07-13 2006-08-22 Calcitec, Inc. Calcium phosphate cement, use and preparation thereof
US7204876B2 (en) * 2000-07-13 2007-04-17 Calcitec, Inc. Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same
US7156915B2 (en) * 2000-07-13 2007-01-02 Calcitec, Inc. Tetracalcium phosphate (TTCP) with surface whiskers and method of making same
US20030216777A1 (en) * 2002-05-16 2003-11-20 Yin-Chun Tien Method of enhancing healing of interfacial gap between bone and tendon or ligament
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EP2365994B1 (en) 2008-11-12 2017-01-04 Howmedica Osteonics Corp. Tetra calcium phosphate based organophosphorus compositions and methods
CA2798710C (en) 2010-05-11 2019-08-27 Venkat R. Garigapati Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods
MY169686A (en) 2011-01-27 2019-05-13 Sirim Berhad A method of converting limestone into tri-calcium phosphate and tetra-calcium phosphate powder simultaneously
WO2012158527A2 (en) 2011-05-13 2012-11-22 Howmedica Osteonics Organophosphorous & multivalent metal compound compositions & methods
US10620065B2 (en) * 2016-12-01 2020-04-14 Ut-Battelle, Llc Cement having stress-indicating properties

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GBURECK, UWE; BARRALAET JAKE E;HOFMANN MICHAEL, THULL ROGER: "Mechanical Activation of Tetracalcium Phosphate", JOURNAL OF THE AMERICAN CERAMICS SOCIETY, vol. 87, no. 2, February 2004 (2004-02-01), pages 311 - 313, XP002336551 *

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EP1711155A2 (en) 2006-10-18

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