WO2005077263A3 - Non-invasive imaging for determining global tissue characteristics - Google Patents

Non-invasive imaging for determining global tissue characteristics Download PDF

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Publication number
WO2005077263A3
WO2005077263A3 PCT/US2005/003763 US2005003763W WO2005077263A3 WO 2005077263 A3 WO2005077263 A3 WO 2005077263A3 US 2005003763 W US2005003763 W US 2005003763W WO 2005077263 A3 WO2005077263 A3 WO 2005077263A3
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WO
WIPO (PCT)
Prior art keywords
image
tissue
tissue characteristics
region
comparison
Prior art date
Application number
PCT/US2005/003763
Other languages
French (fr)
Other versions
WO2005077263A2 (en
Inventor
William Gregory Hundley
Craig A Hamilton
Kimberly Lane
Tim Morgan
Frank Torti
Original Assignee
Univ Wake Forest Health Sciences
William Gregory Hundley
Craig A Hamilton
Kimberly Lane
Tim Morgan
Frank Torti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wake Forest Health Sciences, William Gregory Hundley, Craig A Hamilton, Kimberly Lane, Tim Morgan, Frank Torti filed Critical Univ Wake Forest Health Sciences
Priority to CA2555373A priority Critical patent/CA2555373C/en
Priority to EP05722782A priority patent/EP1725164A2/en
Priority to AU2005212310A priority patent/AU2005212310C1/en
Priority to JP2006552315A priority patent/JP5231736B2/en
Priority to CN2005800120290A priority patent/CN101001569B/en
Publication of WO2005077263A2 publication Critical patent/WO2005077263A2/en
Publication of WO2005077263A3 publication Critical patent/WO2005077263A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/0036—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room including treatment, e.g., using an implantable medical device, ablating, ventilating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/503—Clinical applications involving diagnosis of heart
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/40—Analysis of texture
    • G06T7/41—Analysis of texture based on statistical description of texture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4519—Muscles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computerised tomographs
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/504—Clinical applications involving diagnosis of blood vessels, e.g. by angiography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/506—Clinical applications involving diagnosis of nerves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/281—Means for the use of in vitro contrast agents
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2200/00—Indexing scheme for image data processing or generation, in general
    • G06T2200/24—Indexing scheme for image data processing or generation, in general involving graphical user interfaces [GUIs]
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10088—Magnetic resonance imaging [MRI]
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30048—Heart; Cardiac

Abstract

Evaluating tissue characteristics including identification of injured tissue is provided by obtaining a first image of tissue including a region of interest from a first acquisition, for example, after administration of a contrast agent and obtaining a second image of the tissue including the region of interest during a second, subsequent acquisition, for example, after administration of a contrast agent. A global characteristic of the region of interest of the first image and of the second image is determined to allow a comparison of the global characteristic of the first image and the second image to determine a potential for a change in global tissue characteristics. Such a comparison may include comparison of mean, average characteristics, histogram shape, such as skew and kurtosis, or distribution of intensities within the histogram.
PCT/US2005/003763 2004-02-06 2005-02-04 Non-invasive imaging for determining global tissue characteristics WO2005077263A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA2555373A CA2555373C (en) 2004-02-06 2005-02-04 Tissue evaluation using global tissue characteristics of non-invasive imaging and systems for determining global tissue characteristics of images
EP05722782A EP1725164A2 (en) 2004-02-06 2005-02-04 Non-invasive imaging for determining global tissue characteristics
AU2005212310A AU2005212310C1 (en) 2004-02-06 2005-02-04 Tissue evaluation using global tissue characteristics of non-invasive imaging and systems for determining global tissue characteristics of images
JP2006552315A JP5231736B2 (en) 2004-02-06 2005-02-04 System for evaluating tissue using global tissue characteristics of non-invasive imaging and determining global tissue characteristics of images
CN2005800120290A CN101001569B (en) 2004-02-06 2005-02-04 System for evaluating tissue characteristics and detecting integral cardiac damage of patient

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54254704P 2004-02-06 2004-02-06
US60/542,547 2004-02-06
US11/051,304 US7333845B2 (en) 2004-02-06 2005-02-04 Non-invasive imaging for determination of global tissue characteristics

Publications (2)

Publication Number Publication Date
WO2005077263A2 WO2005077263A2 (en) 2005-08-25
WO2005077263A3 true WO2005077263A3 (en) 2007-03-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/003763 WO2005077263A2 (en) 2004-02-06 2005-02-04 Non-invasive imaging for determining global tissue characteristics

Country Status (7)

Country Link
US (3) US7333845B2 (en)
EP (2) EP2314218B1 (en)
JP (2) JP5231736B2 (en)
CN (1) CN101001569B (en)
AU (1) AU2005212310C1 (en)
CA (1) CA2555373C (en)
WO (1) WO2005077263A2 (en)

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Cited By (1)

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US9240043B2 (en) 2008-09-16 2016-01-19 Novartis Ag Reproducible quantification of biomarker expression

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CA2555373C (en) 2014-04-29
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