WO2005067405A3 - Method for screening responsiveness to drugs effective in treatment or prevention of vitiligo and method for prognosis of vitiligo - Google Patents

Method for screening responsiveness to drugs effective in treatment or prevention of vitiligo and method for prognosis of vitiligo Download PDF

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Publication number
WO2005067405A3
WO2005067405A3 PCT/KR2005/000186 KR2005000186W WO2005067405A3 WO 2005067405 A3 WO2005067405 A3 WO 2005067405A3 KR 2005000186 W KR2005000186 W KR 2005000186W WO 2005067405 A3 WO2005067405 A3 WO 2005067405A3
Authority
WO
WIPO (PCT)
Prior art keywords
vitiligo
prevention
treatment
screening
prognosis
Prior art date
Application number
PCT/KR2005/000186
Other languages
French (fr)
Other versions
WO2005067405A2 (en
Inventor
Ai Young Lee
Nan Hyung Kim
Original Assignee
School Foundation Eulji
Ai Young Lee
Nan Hyung Kim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by School Foundation Eulji, Ai Young Lee, Nan Hyung Kim filed Critical School Foundation Eulji
Publication of WO2005067405A2 publication Critical patent/WO2005067405A2/en
Publication of WO2005067405A3 publication Critical patent/WO2005067405A3/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23NMACHINES OR APPARATUS FOR TREATING HARVESTED FRUIT, VEGETABLES OR FLOWER BULBS IN BULK, NOT OTHERWISE PROVIDED FOR; PEELING VEGETABLES OR FRUIT IN BULK; APPARATUS FOR PREPARING ANIMAL FEEDING- STUFFS
    • A23N17/00Apparatus specially adapted for preparing animal feeding-stuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/32Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from hydrolysates of wood or straw
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/20Dermatological disorders
    • G01N2800/207Pigmentation disorders

Abstract

The present invention relates to methods and kits for screening responsiveness to drugs effective in treatment or prevention of vitiligo, methods and kits for screening active ingredients effective in treatment or prevention of vitiligo, and methods and kits for prognosis of vitiligo using eukaryotic translation initiation factor 4A1 (eIF4A1) gene, ribosomal protein L13 (L13) gene and mediator of RNA polymerase to transcription (MRT) gene.
PCT/KR2005/000186 2004-01-20 2005-01-20 Method for screening responsiveness to drugs effective in treatment or prevention of vitiligo and method for prognosis of vitiligo WO2005067405A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2004-0004256 2004-01-20
KR20040004256 2004-01-20

Publications (2)

Publication Number Publication Date
WO2005067405A2 WO2005067405A2 (en) 2005-07-28
WO2005067405A3 true WO2005067405A3 (en) 2005-09-15

Family

ID=34793288

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2005/000186 WO2005067405A2 (en) 2004-01-20 2005-01-20 Method for screening responsiveness to drugs effective in treatment or prevention of vitiligo and method for prognosis of vitiligo

Country Status (2)

Country Link
KR (1) KR100672853B1 (en)
WO (1) WO2005067405A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100788241B1 (en) * 2007-01-22 2007-12-27 동국대학교 산학협력단 Method for screening materials for preventing or treating vitiligo
KR100951446B1 (en) * 2009-01-23 2010-04-07 동국대학교 산학협력단 Single nucleotide polymorphism of tslp allele for diagnosis of vitiligo susceptibility
KR101146597B1 (en) * 2010-03-16 2012-05-16 동국대학교 산학협력단 Composition for Diagnosis of Vitiligo
CN114591991B (en) * 2022-03-31 2023-05-09 西南交通大学 Method for preparing calcipotriol key chiral intermediate based on short-chain carbonyl reductase

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323219B1 (en) * 1998-04-02 2001-11-27 Ortho-Mcneil Pharmaceutical, Inc. Methods for treating immunomediated inflammatory disorders
US20030059862A1 (en) * 2001-05-24 2003-03-27 Ruben Steven M. Antibodies against tumor necrosis factor delta (APRIL)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6165709A (en) 1997-02-28 2000-12-26 Fred Hutchinson Cancer Research Center Methods for drug target screening
US6324479B1 (en) * 1998-05-08 2001-11-27 Rosetta Impharmatics, Inc. Methods of determining protein activity levels using gene expression profiles
US6218122B1 (en) 1998-06-19 2001-04-17 Rosetta Inpharmatics, Inc. Methods of monitoring disease states and therapies using gene expression profiles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323219B1 (en) * 1998-04-02 2001-11-27 Ortho-Mcneil Pharmaceutical, Inc. Methods for treating immunomediated inflammatory disorders
US20030059862A1 (en) * 2001-05-24 2003-03-27 Ruben Steven M. Antibodies against tumor necrosis factor delta (APRIL)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LE POLE I.C. ET AL: "Altered Gene Expression in Melanocytes Exposed to 4 Tertiary Butyl Phenol (4-TBP): Upregulation of the A2b Adenosine Receptor.", J.INVEST DERMATOL., vol. 113, no. 5, November 1999 (1999-11-01), pages 725 - 731 *
LEE A.Y. ET AL: "All Trans-Retinoic Acid (ATRA) Elevated Eukaryotic Translation Initiation Factor 4A1 (eIF4A1) mRNA in ATRA-Responsive Vitiliginous Epidermis.", PIGMENT CELL RES., vol. 17, no. 6, December 2004 (2004-12-01), pages 659 - 667 *

Also Published As

Publication number Publication date
WO2005067405A2 (en) 2005-07-28
KR100672853B1 (en) 2007-01-22
KR20050076690A (en) 2005-07-26

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