WO2005056625A1 - Novel prepolymers for improved surface modification of contact lenses - Google Patents
Novel prepolymers for improved surface modification of contact lenses Download PDFInfo
- Publication number
- WO2005056625A1 WO2005056625A1 PCT/US2004/040213 US2004040213W WO2005056625A1 WO 2005056625 A1 WO2005056625 A1 WO 2005056625A1 US 2004040213 W US2004040213 W US 2004040213W WO 2005056625 A1 WO2005056625 A1 WO 2005056625A1
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- WIPO (PCT)
- Prior art keywords
- sir
- alkylenes
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- 229910052739 hydrogen Inorganic materials 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- IQPQWNKOIGAROB-UHFFFAOYSA-N isocyanate group Chemical group [N-]=C=O IQPQWNKOIGAROB-UHFFFAOYSA-N 0.000 description 1
- 150000002513 isocyanates Chemical class 0.000 description 1
- WARQUFORVQESFF-UHFFFAOYSA-N isocyanatoethene Chemical class C=CN=C=O WARQUFORVQESFF-UHFFFAOYSA-N 0.000 description 1
- LVHBHZANLOWSRM-UHFFFAOYSA-N itaconic acid Chemical class OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 description 1
- 206010023332 keratitis Diseases 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 150000003951 lactams Chemical class 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000010002 mechanical finishing Methods 0.000 description 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical compound CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 description 1
- 125000005395 methacrylic acid group Chemical group 0.000 description 1
- YDKNBNOOCSNPNS-UHFFFAOYSA-N methyl 1,3-benzoxazole-2-carboxylate Chemical compound C1=CC=C2OC(C(=O)OC)=NC2=C1 YDKNBNOOCSNPNS-UHFFFAOYSA-N 0.000 description 1
- 238000011415 microwave curing Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- WFKDPJRCBCBQNT-UHFFFAOYSA-N n,2-dimethylprop-2-enamide Chemical compound CNC(=O)C(C)=C WFKDPJRCBCBQNT-UHFFFAOYSA-N 0.000 description 1
- WAUMXMQJIMQTJK-UHFFFAOYSA-N n,n'-dihydroxyocta-2,6-dienediamide Chemical compound ONC(=O)C=CCCC=CC(=O)NO WAUMXMQJIMQTJK-UHFFFAOYSA-N 0.000 description 1
- QRWZCJXEAOZAAW-UHFFFAOYSA-N n,n,2-trimethylprop-2-enamide Chemical compound CN(C)C(=O)C(C)=C QRWZCJXEAOZAAW-UHFFFAOYSA-N 0.000 description 1
- GORGQKRVQGXVEB-UHFFFAOYSA-N n-ethenyl-n-ethylacetamide Chemical compound CCN(C=C)C(C)=O GORGQKRVQGXVEB-UHFFFAOYSA-N 0.000 description 1
- PNLUGRYDUHRLOF-UHFFFAOYSA-N n-ethenyl-n-methylacetamide Chemical compound C=CN(C)C(C)=O PNLUGRYDUHRLOF-UHFFFAOYSA-N 0.000 description 1
- ZQXSMRAEXCEDJD-UHFFFAOYSA-N n-ethenylformamide Chemical compound C=CNC=O ZQXSMRAEXCEDJD-UHFFFAOYSA-N 0.000 description 1
- YPHQUSNPXDGUHL-UHFFFAOYSA-N n-methylprop-2-enamide Chemical compound CNC(=O)C=C YPHQUSNPXDGUHL-UHFFFAOYSA-N 0.000 description 1
- XNTUJOTWIMFEQS-UHFFFAOYSA-N octadecanoyl octadecaneperoxoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OOC(=O)CCCCCCCCCCCCCCCCC XNTUJOTWIMFEQS-UHFFFAOYSA-N 0.000 description 1
- 125000000962 organic group Chemical group 0.000 description 1
- 150000001451 organic peroxides Chemical class 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920000233 poly(alkylene oxides) Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000010526 radical polymerization reaction Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000004528 spin coating Methods 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 238000005211 surface analysis Methods 0.000 description 1
- 229920001897 terpolymer Polymers 0.000 description 1
- 238000001029 thermal curing Methods 0.000 description 1
- 238000012719 thermal polymerization Methods 0.000 description 1
- 239000012745 toughening agent Substances 0.000 description 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
- LVLANIHJQRZTPY-UHFFFAOYSA-N vinyl carbamate Chemical compound NC(=O)OC=C LVLANIHJQRZTPY-UHFFFAOYSA-N 0.000 description 1
- UIYCHXAGWOYNNA-UHFFFAOYSA-N vinyl sulfide Chemical group C=CSC=C UIYCHXAGWOYNNA-UHFFFAOYSA-N 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/38—Polysiloxanes modified by chemical after-treatment
- C08G77/382—Polysiloxanes modified by chemical after-treatment containing atoms other than carbon, hydrogen, oxygen or silicon
- C08G77/388—Polysiloxanes modified by chemical after-treatment containing atoms other than carbon, hydrogen, oxygen or silicon containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F230/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal
- C08F230/04—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal
- C08F230/08—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing silicon
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
- C08F283/12—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
- C08F290/068—Polysiloxanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/38—Polysiloxanes modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
- C08L51/08—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds
- C08L51/085—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds on to polysiloxanes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Transplantation (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- General Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Eyeglasses (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Prostheses (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Silicon Polymers (AREA)
- Polyurethanes Or Polyureas (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE602004014537T DE602004014537D1 (en) | 2003-12-05 | 2004-12-01 | NEW PREPOLYMERS FOR IMPROVED SURFACE MODIFICATION OF CONTACT LENSES |
CA002547463A CA2547463A1 (en) | 2003-12-05 | 2004-12-01 | Novel prepolymers for improved surface modification of contact lenses |
EP04812667A EP1706438B1 (en) | 2003-12-05 | 2004-12-01 | Novel prepolymers for improved surface modification of contact lenses |
JP2006542705A JP2007513249A (en) | 2003-12-05 | 2004-12-01 | New prepolymers for improved surface modification of contact lenses |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/728,711 | 2003-12-05 | ||
US10/728,711 US7176268B2 (en) | 2003-12-05 | 2003-12-05 | Prepolymers for improved surface modification of contact lenses |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005056625A1 true WO2005056625A1 (en) | 2005-06-23 |
Family
ID=34633784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/040213 WO2005056625A1 (en) | 2003-12-05 | 2004-12-01 | Novel prepolymers for improved surface modification of contact lenses |
Country Status (10)
Country | Link |
---|---|
US (2) | US7176268B2 (en) |
EP (1) | EP1706438B1 (en) |
JP (1) | JP2007513249A (en) |
CN (1) | CN1906222A (en) |
AT (1) | ATE398637T1 (en) |
CA (1) | CA2547463A1 (en) |
DE (1) | DE602004014537D1 (en) |
ES (1) | ES2308297T3 (en) |
TW (1) | TWI287022B (en) |
WO (1) | WO2005056625A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009528402A (en) * | 2006-02-24 | 2009-08-06 | ルブリゾル アドバンスド マテリアルズ, インコーポレイテッド | Polymerizable silicone copolyol macromer and polymers made therefrom |
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US8586149B2 (en) * | 2003-06-18 | 2013-11-19 | Ford Global Technologies, Llc | Environmentally friendly reactive fixture to allow localized surface engineering for improved adhesion to coated and non-coated substrates |
US7411029B2 (en) * | 2004-06-25 | 2008-08-12 | Bausch & Lomb Incorporated | Prepolymers for improved surface modification of contact lenses |
US7517561B2 (en) * | 2005-09-21 | 2009-04-14 | Ford Global Technologies, Llc | Method of coating a substrate for adhesive bonding |
US7744984B2 (en) * | 2006-06-28 | 2010-06-29 | Ford Global Technologies, Llc | Method of treating substrates for bonding |
US20080004413A1 (en) * | 2006-06-30 | 2008-01-03 | Derek Schorzman | Carboxylic M2Dx-like siloxanyl monomers |
US7935770B2 (en) * | 2007-07-03 | 2011-05-03 | Bausch & Lomb Incorporated | Surface active prepolymers with both fluorine-containing groups and hydrophilic groups |
US20090111905A1 (en) * | 2007-10-31 | 2009-04-30 | Ture Kindt-Larsen | Process for forming random (meth)acrylate containing prepolymers |
US7884141B2 (en) * | 2007-11-14 | 2011-02-08 | Bausch & Lomb Incorporated | Biomedical devices |
WO2009079223A1 (en) * | 2007-12-14 | 2009-06-25 | Bausch & Lomb Incorporated | Surface modified biomedical devices |
WO2009079245A2 (en) * | 2007-12-14 | 2009-06-25 | Bausch & Lomb Incorporated | Biomedical devices |
WO2009079224A2 (en) * | 2007-12-14 | 2009-06-25 | Bausch & Lomb Incorporated | Surface modified biomedical devices |
WO2009085756A1 (en) * | 2007-12-27 | 2009-07-09 | Bausch & Lomb Incorporated | Coating solutions comprising segmented interactive block copolymers |
US7850878B2 (en) * | 2007-12-31 | 2010-12-14 | Bausch & Lomb Incorporated | Method of forming a biomedical device including an ophthalmic device |
US8940219B2 (en) | 2007-12-31 | 2015-01-27 | Ronald D. Spoor | Ophthalmic device formed by additive fabrication and method thereof |
US20100151236A1 (en) * | 2008-12-11 | 2010-06-17 | Ford Global Technologies, Llc | Surface treatment for polymeric part adhesion |
TWI477560B (en) * | 2013-02-07 | 2015-03-21 | Benq Materials Corp | Material for contact lenses, method for manufacturing contact lenses and contact lenses obtained thereby |
US10160854B1 (en) | 2015-08-03 | 2018-12-25 | Gl Chemtec Vision Inc. | Hydrogel materials |
JP2019517599A (en) * | 2016-06-03 | 2019-06-24 | シラス・インコーポレイテッド | Polymers and other compounds functionalized with terminal 1,1-disubstituted alkene monomers and methods thereof |
JP6863569B2 (en) * | 2016-11-30 | 2021-04-21 | 共栄社化学株式会社 | Surface conditioner for coating agents |
TWI640557B (en) * | 2017-07-05 | 2018-11-11 | 晶碩光學股份有限公司 | Contact lens with surface modification and the method for its preparation |
US11867875B2 (en) * | 2018-09-25 | 2024-01-09 | Nof Corporation | Monomer composition for contact lenses, polymer for contact lenses, contact lens, and method of producing the contact lens |
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-
2003
- 2003-12-05 US US10/728,711 patent/US7176268B2/en not_active Expired - Fee Related
-
2004
- 2004-12-01 AT AT04812667T patent/ATE398637T1/en not_active IP Right Cessation
- 2004-12-01 CN CNA2004800410477A patent/CN1906222A/en active Pending
- 2004-12-01 DE DE602004014537T patent/DE602004014537D1/en not_active Expired - Fee Related
- 2004-12-01 EP EP04812667A patent/EP1706438B1/en not_active Not-in-force
- 2004-12-01 WO PCT/US2004/040213 patent/WO2005056625A1/en active Application Filing
- 2004-12-01 JP JP2006542705A patent/JP2007513249A/en not_active Withdrawn
- 2004-12-01 ES ES04812667T patent/ES2308297T3/en active Active
- 2004-12-01 CA CA002547463A patent/CA2547463A1/en not_active Abandoned
- 2004-12-03 TW TW093137488A patent/TWI287022B/en not_active IP Right Cessation
-
2006
- 2006-12-26 US US11/616,097 patent/US20070129521A1/en not_active Abandoned
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US4686267A (en) * | 1985-10-11 | 1987-08-11 | Polymer Technology Corporation | Fluorine containing polymeric compositions useful in contact lenses |
US4743106A (en) * | 1986-02-06 | 1988-05-10 | Maureen J. Devou | Highly oxygen permeable contact lens materials and compositions thereof |
US20020102415A1 (en) * | 1999-05-20 | 2002-08-01 | Paul L. Valint | Surface treatment of silicone hydrogel contact lenses comprising hydrophilic polymer chains attached to an intermediate carbon coating |
US20030109661A1 (en) * | 2001-11-02 | 2003-06-12 | Salamone Joseph C. | High refractive index polymeric siloxysilane compositions |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009528402A (en) * | 2006-02-24 | 2009-08-06 | ルブリゾル アドバンスド マテリアルズ, インコーポレイテッド | Polymerizable silicone copolyol macromer and polymers made therefrom |
US8796484B2 (en) | 2006-02-24 | 2014-08-05 | Lubrizol Advanced Materials, Inc. | Polymerizable silicone copolyol macromers and polymers made therefrom |
Also Published As
Publication number | Publication date |
---|---|
TW200535153A (en) | 2005-11-01 |
EP1706438B1 (en) | 2008-06-18 |
CN1906222A (en) | 2007-01-31 |
ES2308297T3 (en) | 2008-12-01 |
TWI287022B (en) | 2007-09-21 |
CA2547463A1 (en) | 2005-06-23 |
US20050124776A1 (en) | 2005-06-09 |
US20070129521A1 (en) | 2007-06-07 |
US7176268B2 (en) | 2007-02-13 |
ATE398637T1 (en) | 2008-07-15 |
DE602004014537D1 (en) | 2008-07-31 |
EP1706438A1 (en) | 2006-10-04 |
JP2007513249A (en) | 2007-05-24 |
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