WO2005055929A3 - Methods and compositions for the treatment and management of hemoglobinopathy and anemia - Google Patents
Methods and compositions for the treatment and management of hemoglobinopathy and anemia Download PDFInfo
- Publication number
- WO2005055929A3 WO2005055929A3 PCT/US2004/040226 US2004040226W WO2005055929A3 WO 2005055929 A3 WO2005055929 A3 WO 2005055929A3 US 2004040226 W US2004040226 W US 2004040226W WO 2005055929 A3 WO2005055929 A3 WO 2005055929A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compounds
- genes
- dione
- amino
- anemia
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0417186-1A BRPI0417186A (en) | 2003-12-02 | 2004-12-02 | method of treating an individual having a hemoglobinopathy or anemia, modulating the differentiation of a cd34 + stem cell or precursor into an erythroid lineage, and, pharmaceutical composition |
MXPA06006061A MXPA06006061A (en) | 2003-12-02 | 2004-12-02 | Methods and compositions for the treatment and management of hemoglobinopathy and anemia. |
NZ548049A NZ548049A (en) | 2003-12-02 | 2004-12-02 | Methods and compositions for the treatment and management of hemoglobinopathy and anemia |
EP04812678A EP1694328A4 (en) | 2003-12-02 | 2004-12-02 | Methods and compositions for the treatment and management of hemoglobinopathy and anemia |
CN2004800412523A CN1913896B (en) | 2003-12-02 | 2004-12-02 | Methods and compositions for the treatment and management of hemoglobinopathy and anemia |
AU2004296765A AU2004296765B2 (en) | 2003-12-02 | 2004-12-02 | Methods and compositions for the treatment and management of hemoglobinopathy and anemia |
CA002547570A CA2547570A1 (en) | 2003-12-02 | 2004-12-02 | 4-(amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1,3-dione for induction of fetal hemoglobin in individuals having anemia |
JP2006542711A JP5089170B2 (en) | 2003-12-02 | 2004-12-02 | Methods and compositions for the treatment and management of abnormal hemoglobinosis and anemia |
IL176020A IL176020A0 (en) | 2003-12-02 | 2006-05-30 | Methods and compositions for the treatment and management of hemoglobinopathy and anemia |
HK07108315.4A HK1100262A1 (en) | 2003-12-02 | 2007-07-31 | Methods and compositions for the treatment and management of hemoglobinopathy and anemia |
AU2011202457A AU2011202457B2 (en) | 2003-12-02 | 2011-05-26 | Methods and compositions for the treatment and management of hemoglobinopathy and anemia |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52691003P | 2003-12-02 | 2003-12-02 | |
US60/526,910 | 2003-12-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005055929A2 WO2005055929A2 (en) | 2005-06-23 |
WO2005055929A3 true WO2005055929A3 (en) | 2006-01-05 |
Family
ID=34676680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/040226 WO2005055929A2 (en) | 2003-12-02 | 2004-12-02 | Methods and compositions for the treatment and management of hemoglobinopathy and anemia |
Country Status (14)
Country | Link |
---|---|
US (1) | US20050143420A1 (en) |
EP (1) | EP1694328A4 (en) |
JP (2) | JP5089170B2 (en) |
KR (3) | KR20110116225A (en) |
CN (2) | CN101966183A (en) |
AU (2) | AU2004296765B2 (en) |
BR (1) | BRPI0417186A (en) |
CA (1) | CA2547570A1 (en) |
HK (1) | HK1100262A1 (en) |
IL (1) | IL176020A0 (en) |
MX (1) | MXPA06006061A (en) |
NZ (1) | NZ548049A (en) |
WO (1) | WO2005055929A2 (en) |
ZA (1) | ZA200604815B (en) |
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US8691217B2 (en) | 2005-12-29 | 2014-04-08 | Anthrogenesis Corporation | Placental stem cell populations |
US8889411B2 (en) | 2002-04-12 | 2014-11-18 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
US8926964B2 (en) | 2010-07-13 | 2015-01-06 | Anthrogenesis Corporation | Methods of generating natural killer cells |
US8969315B2 (en) | 2010-12-31 | 2015-03-03 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
US9121007B2 (en) | 2010-01-26 | 2015-09-01 | Anthrogenesis Corporatin | Treatment of bone-related cancers using placental stem cells |
US9216200B2 (en) | 2007-09-28 | 2015-12-22 | Anthrogenesis Corporation | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
US9254302B2 (en) | 2010-04-07 | 2016-02-09 | Anthrogenesis Corporation | Angiogenesis using placental stem cells |
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HU228769B1 (en) * | 1996-07-24 | 2013-05-28 | Celgene Corp | Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha |
US7629360B2 (en) * | 1999-05-07 | 2009-12-08 | Celgene Corporation | Methods for the treatment of cachexia and graft v. host disease |
US6458810B1 (en) | 2000-11-14 | 2002-10-01 | George Muller | Pharmaceutically active isoindoline derivatives |
AU2002220209B2 (en) | 2000-12-06 | 2006-05-25 | Robert J. Hariri | Method of collecting placental stem cells |
US7311905B2 (en) | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
US20030032179A1 (en) * | 2000-12-06 | 2003-02-13 | Hariri Robert J. | Post-partum mammalian placenta, its use and placental stem cells therefrom |
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US6942802B2 (en) * | 2001-04-13 | 2005-09-13 | Wyeth Holdings Corporation | Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography |
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US8586360B2 (en) | 2009-07-02 | 2013-11-19 | Anthrogenesis Corporation | Method of producing erythrocytes without feeder cells |
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US9121007B2 (en) | 2010-01-26 | 2015-09-01 | Anthrogenesis Corporatin | Treatment of bone-related cancers using placental stem cells |
US9254302B2 (en) | 2010-04-07 | 2016-02-09 | Anthrogenesis Corporation | Angiogenesis using placental stem cells |
US8926964B2 (en) | 2010-07-13 | 2015-01-06 | Anthrogenesis Corporation | Methods of generating natural killer cells |
US9464274B2 (en) | 2010-07-13 | 2016-10-11 | Anthrogenesis Corporation | Methods of generating natural killer cells |
US8969315B2 (en) | 2010-12-31 | 2015-03-03 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
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JP5089170B2 (en) | 2012-12-05 |
IL176020A0 (en) | 2006-10-05 |
MXPA06006061A (en) | 2006-08-11 |
NZ548049A (en) | 2009-01-31 |
WO2005055929A2 (en) | 2005-06-23 |
EP1694328A2 (en) | 2006-08-30 |
BRPI0417186A (en) | 2007-03-06 |
JP2011207906A (en) | 2011-10-20 |
CA2547570A1 (en) | 2005-06-23 |
KR20110116225A (en) | 2011-10-25 |
KR20120039065A (en) | 2012-04-24 |
KR20060109979A (en) | 2006-10-23 |
US20050143420A1 (en) | 2005-06-30 |
CN101966183A (en) | 2011-02-09 |
AU2004296765B2 (en) | 2011-03-24 |
AU2011202457A1 (en) | 2011-06-16 |
HK1100262A1 (en) | 2007-09-14 |
CN1913896B (en) | 2010-12-01 |
JP2007513164A (en) | 2007-05-24 |
CN1913896A (en) | 2007-02-14 |
EP1694328A4 (en) | 2010-02-17 |
AU2004296765A1 (en) | 2005-06-23 |
ZA200604815B (en) | 2007-10-31 |
AU2011202457B2 (en) | 2012-11-08 |
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