WO2005050207A3 - Diffraction grating-based encoded articles for multiplexed experiments - Google Patents

Diffraction grating-based encoded articles for multiplexed experiments Download PDF

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Publication number
WO2005050207A3
WO2005050207A3 PCT/US2004/038416 US2004038416W WO2005050207A3 WO 2005050207 A3 WO2005050207 A3 WO 2005050207A3 US 2004038416 W US2004038416 W US 2004038416W WO 2005050207 A3 WO2005050207 A3 WO 2005050207A3
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WO
WIPO (PCT)
Prior art keywords
assay
methods
analytes
article
compositions
Prior art date
Application number
PCT/US2004/038416
Other languages
French (fr)
Other versions
WO2005050207A2 (en
Inventor
John A Moon
Martin A Putnam
Michel Perbost
John Joseph Quinn
Mary Catherine Trounstine
Original Assignee
Cyvera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/763,995 external-priority patent/US7164533B2/en
Application filed by Cyvera Corp filed Critical Cyvera Corp
Priority to CA002545441A priority Critical patent/CA2545441A1/en
Priority to EP04811206A priority patent/EP1723419A2/en
Publication of WO2005050207A2 publication Critical patent/WO2005050207A2/en
Publication of WO2005050207A3 publication Critical patent/WO2005050207A3/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/005Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00502Particles of irregular geometry
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00542Alphanumeric characters
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554Physical means
    • B01J2219/0056Raised or sunken areas
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572Chemical means
    • B01J2219/00576Chemical means fluorophore
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00725Peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742Type of codes
    • G01N2035/00772Type of codes mechanical or optical code other than bar code

Abstract

The present invention provides methods and compositions directed toward assays of a broad range of analytes using specific targeting chemicals that bind to the analytes. The assays are founded on the use of coded assay articles to which the targeting chemicals are attached. Additionally the codes are such that they are interrogated and determined in real time. The target is analyzed as to identity, presence and quantity in real time. The methods and compositions of the invention are highly suitable for use in high-complexity multiplexed assay systems. All the methods and compositions are based on assay article that includes an optical substrate to which the chemical is bound, and in which is disposed at least one diffraction grating. The grating provides an output optical signal when illuminated by an incident light signal which is indicative of the code in the substrate. In general, coded assay article or sets thereof are employed in assay methods, including multiplexed assay methods, according to which a sample is contacted with an article or a set, and any analytes that bind to the attached chemical are identified according to the code, detected and/or quantitated.
PCT/US2004/038416 2003-11-14 2004-11-15 Diffraction grating-based encoded articles for multiplexed experiments WO2005050207A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002545441A CA2545441A1 (en) 2003-11-14 2004-11-15 Diffraction grating-based encoded articles for multiplexed experiments
EP04811206A EP1723419A2 (en) 2003-11-14 2004-11-15 Diffraction grating-based encoded articles for multiplexed experiments

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US51993203P 2003-11-14 2003-11-14
US60/519,932 2003-11-14
US10/763,995 2004-01-22
US10/763,995 US7164533B2 (en) 2003-01-22 2004-01-22 Hybrid random bead/chip based microarray
US55544904P 2004-03-22 2004-03-22
US60/555,449 2004-03-22
US60242704P 2004-08-18 2004-08-18
US60/602,427 2004-08-18
US61120504P 2004-09-17 2004-09-17
US60/611,205 2004-09-17
US61167604P 2004-09-20 2004-09-20
US60/611,676 2004-09-20

Publications (2)

Publication Number Publication Date
WO2005050207A2 WO2005050207A2 (en) 2005-06-02
WO2005050207A3 true WO2005050207A3 (en) 2005-12-29

Family

ID=34624129

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/038416 WO2005050207A2 (en) 2003-11-14 2004-11-15 Diffraction grating-based encoded articles for multiplexed experiments

Country Status (3)

Country Link
EP (1) EP1723419A2 (en)
CA (1) CA2545441A1 (en)
WO (1) WO2005050207A2 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7659983B2 (en) 2003-01-22 2010-02-09 Electronics And Telecommunications Resarch Institute Hybrid random bead/chip based microarray
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7898735B2 (en) 2002-09-12 2011-03-01 Illumina, Inc. Methods and systems for writing an optical code within or on a fiber substrate
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US8081792B2 (en) 2003-08-20 2011-12-20 Illumina, Inc. Fourier scattering methods for encoding microbeads and methods and apparatus for reading the same

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9285362B2 (en) 2006-10-18 2016-03-15 Axela, Inc. Measuring multiple analytes over a broad range of concentrations using optical diffraction
US8338189B2 (en) 2008-03-05 2012-12-25 Axela Inc. Detection of biomarkers and biomarker complexes
CN110082501B (en) * 2019-04-29 2021-05-28 中南大学 Geological core space attitude restoration device

Citations (7)

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US4011435A (en) * 1974-02-01 1977-03-08 Ncr Corporation Optical indicia marking and detection system
US6096496A (en) * 1997-06-19 2000-08-01 Frankel; Robert D. Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis
WO2001071322A2 (en) * 2000-03-22 2001-09-27 Goh M Cynthia Method and apparatus for multiple-analyte assay
US6340588B1 (en) * 1995-04-25 2002-01-22 Discovery Partners International, Inc. Matrices with memories
US20030129654A1 (en) * 1999-04-15 2003-07-10 Ilya Ravkin Coded particles for multiplexed analysis of biological samples
WO2004025562A1 (en) * 2002-09-12 2004-03-25 Cyvera Corp. Method and apparatus for labelling using diffraction grating-based encoded optical identification elements
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Patent Citations (7)

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US4011435A (en) * 1974-02-01 1977-03-08 Ncr Corporation Optical indicia marking and detection system
US6340588B1 (en) * 1995-04-25 2002-01-22 Discovery Partners International, Inc. Matrices with memories
US6096496A (en) * 1997-06-19 2000-08-01 Frankel; Robert D. Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis
US20030129654A1 (en) * 1999-04-15 2003-07-10 Ilya Ravkin Coded particles for multiplexed analysis of biological samples
WO2001071322A2 (en) * 2000-03-22 2001-09-27 Goh M Cynthia Method and apparatus for multiple-analyte assay
WO2004025562A1 (en) * 2002-09-12 2004-03-25 Cyvera Corp. Method and apparatus for labelling using diffraction grating-based encoded optical identification elements
US20040126875A1 (en) * 2002-09-12 2004-07-01 Putnam Martin A. Assay stick

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICEWARNER-PENA S R ET AL: "SUBMICROMETER METALLIC BARCODES", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 294, no. 5540, 5 October 2001 (2001-10-05), pages 137 - 141, XP001128112, ISSN: 0036-8075 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7898735B2 (en) 2002-09-12 2011-03-01 Illumina, Inc. Methods and systems for writing an optical code within or on a fiber substrate
US7659983B2 (en) 2003-01-22 2010-02-09 Electronics And Telecommunications Resarch Institute Hybrid random bead/chip based microarray
US9268983B2 (en) 2003-01-22 2016-02-23 Illumina, Inc. Optical system and method for reading encoded microbeads
US8081792B2 (en) 2003-08-20 2011-12-20 Illumina, Inc. Fourier scattering methods for encoding microbeads and methods and apparatus for reading the same
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time

Also Published As

Publication number Publication date
WO2005050207A2 (en) 2005-06-02
CA2545441A1 (en) 2005-06-02
EP1723419A2 (en) 2006-11-22

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