WO2005047849A3 - Methods and apparatus for the improved measurment of circular and linear dichroism and uses thereof - Google Patents

Methods and apparatus for the improved measurment of circular and linear dichroism and uses thereof Download PDF

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Publication number
WO2005047849A3
WO2005047849A3 PCT/US2004/027402 US2004027402W WO2005047849A3 WO 2005047849 A3 WO2005047849 A3 WO 2005047849A3 US 2004027402 W US2004027402 W US 2004027402W WO 2005047849 A3 WO2005047849 A3 WO 2005047849A3
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WO
WIPO (PCT)
Prior art keywords
polarizers
methods
present
tandem array
measurment
Prior art date
Application number
PCT/US2004/027402
Other languages
French (fr)
Other versions
WO2005047849A2 (en
Inventor
Laurence A Nafie
L Henry Buijs
Original Assignee
Biotools Inc
Laurence A Nafie
L Henry Buijs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotools Inc, Laurence A Nafie, L Henry Buijs filed Critical Biotools Inc
Publication of WO2005047849A2 publication Critical patent/WO2005047849A2/en
Publication of WO2005047849A3 publication Critical patent/WO2005047849A3/en
Priority to US11/358,531 priority Critical patent/US7522283B2/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/19—Dichroism

Abstract

The present invention is directed generally to an apparatus and methods that combine a novel four-port dual-source interferometer with double modulation FT-VCD or FT-VLD measurements to obtain a spectrometer with enhanced signal quality (S/N), and lower susceptibility to detector saturation. In the novel apparatus of the present invention, a linear polarizer or tandem array of identically-oriented polarizers is placed in front of each of the two sources in a four-port dual-source interferometer, with the polarization state of one of the linear polarizers (or tandem array of polarizers) vertical and the polarization state of the other linear polarizer (or tandem array of polarixers) horizontal, i.e., with the polarization axes of the polarizers orthogonal to one another. Methods for measuring these spectra using the various aspects of the apparatus of the present invention are also provided.
PCT/US2004/027402 2003-08-21 2004-08-23 Methods and apparatus for the improved measurment of circular and linear dichroism and uses thereof WO2005047849A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US11/358,531 US7522283B2 (en) 2004-08-23 2006-02-21 Methods and apparatus for the improved measurement of circular and linear dichroism and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49679603P 2003-08-21 2003-08-21
US60/496,796 2003-08-21

Publications (2)

Publication Number Publication Date
WO2005047849A2 WO2005047849A2 (en) 2005-05-26
WO2005047849A3 true WO2005047849A3 (en) 2005-11-17

Family

ID=34590084

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/027402 WO2005047849A2 (en) 2003-08-21 2004-08-23 Methods and apparatus for the improved measurment of circular and linear dichroism and uses thereof

Country Status (1)

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WO (1) WO2005047849A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108548791A (en) * 2018-02-05 2018-09-18 广东研捷医药科技有限公司 A kind of absolute configuration identification method of metconazole diastereoisomer
DE102019118003B3 (en) 2019-07-03 2020-10-22 Leibniz-Institut für Photonische Technologien e. V. Microscopy arrangement and microscopy method for large-area, high-resolution chiral imaging and their use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3728030A (en) * 1970-06-22 1973-04-17 Cary Instruments Polarization interferometer
US5450196A (en) * 1993-08-20 1995-09-12 Perkin-Elmer Limited Time-resolved Fourier-transform optical spectroscopy utilizing in-phase and quadrature cyclic perturbation data values
US6233054B1 (en) * 1998-04-10 2001-05-15 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Of Her Majesty's Canadian Government Fourier-transform spectrometer configuration optimized for self emission suppression and simplified radiometric calibration

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3728030A (en) * 1970-06-22 1973-04-17 Cary Instruments Polarization interferometer
US5450196A (en) * 1993-08-20 1995-09-12 Perkin-Elmer Limited Time-resolved Fourier-transform optical spectroscopy utilizing in-phase and quadrature cyclic perturbation data values
US6233054B1 (en) * 1998-04-10 2001-05-15 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Of Her Majesty's Canadian Government Fourier-transform spectrometer configuration optimized for self emission suppression and simplified radiometric calibration

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GRIFFITHS P.R. ET AL: "Fourier Transform Infrared Spectrometry.", 1986, XP008053036 *

Also Published As

Publication number Publication date
WO2005047849A2 (en) 2005-05-26

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