WO2005046640A3 - Multi-site drug delivery platform - Google Patents

Multi-site drug delivery platform Download PDF

Info

Publication number
WO2005046640A3
WO2005046640A3 PCT/US2004/036935 US2004036935W WO2005046640A3 WO 2005046640 A3 WO2005046640 A3 WO 2005046640A3 US 2004036935 W US2004036935 W US 2004036935W WO 2005046640 A3 WO2005046640 A3 WO 2005046640A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug delivery
delivery platform
site drug
physiologically
patient body
Prior art date
Application number
PCT/US2004/036935
Other languages
French (fr)
Other versions
WO2005046640A2 (en
Inventor
Gilbert R Gonzales
Paolo L Manfredi
Original Assignee
Pediamed Pharmaceuticals Inc
Gilbert R Gonzales
Paolo L Manfredi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pediamed Pharmaceuticals Inc, Gilbert R Gonzales, Paolo L Manfredi filed Critical Pediamed Pharmaceuticals Inc
Priority to CA002543815A priority Critical patent/CA2543815A1/en
Priority to EP04810400A priority patent/EP1680081A2/en
Priority to JP2006538507A priority patent/JP2007510663A/en
Publication of WO2005046640A2 publication Critical patent/WO2005046640A2/en
Publication of WO2005046640A3 publication Critical patent/WO2005046640A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015—Devices specially adapted for taking medicines
    • A61J7/003—Sticks, e.g. lollipops with drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/08—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of suppositories or sticks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015—Devices specially adapted for taking medicines
    • A61J7/0053—Syringes, pipettes or oral dispensers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A61K9/025—Suppositories; Bougies; Bases therefor; Ovules characterised by shape or structure, e.g. hollow layered, coated

Abstract

A pharmaceutical composition (10) for administration to a patient body. The composition (10) includes a physiologically-acceptable formulation including at least one active pharmaceutical ingredient, wherein said physiologically-acceptable formulation including said at least one active pharmaceutical ingredient is provided in a delivery form (12), said delivery form (12) being administrable to a patient body through a plurality of administration routes, which include the oral and rectal routes.
PCT/US2004/036935 2003-11-06 2004-11-05 Multi-site drug delivery platform WO2005046640A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002543815A CA2543815A1 (en) 2003-11-06 2004-11-05 Multi-site drug delivery platform
EP04810400A EP1680081A2 (en) 2003-11-06 2004-11-05 Multi-site drug delivery platform
JP2006538507A JP2007510663A (en) 2003-11-06 2004-11-05 Multi-site drug transfer platform

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/702,893 US8157788B2 (en) 2003-11-06 2003-11-06 Multi-site drug delivery platform
US10/702,893 2003-11-06

Publications (2)

Publication Number Publication Date
WO2005046640A2 WO2005046640A2 (en) 2005-05-26
WO2005046640A3 true WO2005046640A3 (en) 2006-07-13

Family

ID=34551762

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/036935 WO2005046640A2 (en) 2003-11-06 2004-11-05 Multi-site drug delivery platform

Country Status (5)

Country Link
US (1) US8157788B2 (en)
EP (1) EP1680081A2 (en)
JP (1) JP2007510663A (en)
CA (1) CA2543815A1 (en)
WO (1) WO2005046640A2 (en)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
WO2004037225A2 (en) 2002-10-25 2004-05-06 Foamix Ltd. Cosmetic and pharmaceutical foam
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US20060024236A1 (en) * 2004-07-27 2006-02-02 Pickhardt Perry J Bowel preparation for virtual colonoscopy
US20070104763A1 (en) * 2005-11-10 2007-05-10 Navinta Llc Composition of fentanyl citrate oral solid transmucosal dosage form, excipient and binding material therefore, and methods of making
US8252328B2 (en) 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US8753308B2 (en) 2006-01-06 2014-06-17 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US9066847B2 (en) 2007-01-05 2015-06-30 Aceirx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8357114B2 (en) 2006-01-06 2013-01-22 Acelrx Pharmaceuticals, Inc. Drug dispensing device with flexible push rod
US9289583B2 (en) 2006-01-06 2016-03-22 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US20070282241A1 (en) * 2006-05-31 2007-12-06 Squires Meryl J Applicator system
US20070299687A1 (en) * 2006-06-23 2007-12-27 Pamela Palmer Inpatient system for patient-controlled delivery of oral transmucosal medications dosed as needed
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
CN101563071A (en) * 2006-12-01 2009-10-21 赛福伦公司 Oral transmucosal nicotine dosage form
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
EP2242476A2 (en) 2008-01-14 2010-10-27 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
US9040089B2 (en) * 2008-07-22 2015-05-26 Lupin Limited Oral compositions of clindamycin
US8945592B2 (en) 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
WO2010107761A1 (en) 2009-03-18 2010-09-23 Acelrx Pharmaceuticals, Inc. Improved storage and dispensing devices for administration of oral transmucosal dosage forms
CA2760186C (en) 2009-04-28 2019-10-29 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
US8945516B2 (en) 2009-10-02 2015-02-03 Foamix Pharmaceuticals Ltd. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US8174881B2 (en) 2009-11-24 2012-05-08 Micron Technology, Inc. Techniques for reducing disturbance in a semiconductor device
CN105451723A (en) * 2013-06-26 2016-03-30 爱荷华大学研究基金会 Oral drug delivery device and methods of using same
US9700549B2 (en) 2013-10-03 2017-07-11 David Wise Compositions and methods for treating pelvic pain and other conditions
WO2016106329A1 (en) 2014-12-23 2016-06-30 Acelrx Pharmaceuticals, Inc. Systems, devices and methods for dispensing oral transmucosal dosage forms
CA2978573A1 (en) 2016-09-08 2018-03-08 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405597A (en) * 1981-02-24 1983-09-20 Shin-Etsu Chemical Co., Ltd. Medicament capsules for rectal application
WO1990003776A1 (en) * 1988-10-14 1990-04-19 Zetachron, Inc. Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith
WO1991003099A1 (en) * 1985-05-01 1991-03-07 Anesta Corporation Compressed powder medicaments
GB2314024A (en) * 1996-06-13 1997-12-17 American Home Prod A novel suppository
WO2001089473A1 (en) * 2000-05-26 2001-11-29 Nycomed Austria Gmbh Pharmaceutical compositions comprising desglymidodrine as an active drug substance

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH478762A (en) * 1966-10-07 1969-09-30 Geigy Ag J R Process for the production of new substituted cinnamic acids
US3574820A (en) * 1968-01-08 1971-04-13 Upjohn Co Medicinal dosage forms of unpolymerized thiolated gelatin with a cross-linking accelerating agent providing slowly released medication from a swollen matrix
US4028467A (en) * 1975-01-07 1977-06-07 Berger Frank M Analgesic compositions comprising levo-propoxyphene and benzo diazepine and process
US4258027A (en) * 1979-03-26 1981-03-24 Mead Johnson & Company Multi-fractionable tablet structure
US4339442A (en) * 1980-03-11 1982-07-13 Tsunematsu Takemoto Gynosaponins, their use and a process for preparing the same
CH649080A5 (en) * 1981-04-16 1985-04-30 Ciba Geigy Ag 5H-DIBENZ (B, F) AZEPINE-5-CARBOXAMIDES AS A MEDICINE FOR PROPHYLAXIS AND TREATMENT OF CEREBRAL PERFORMANCE INSUFFICIENCY.
DK406686D0 (en) * 1986-08-26 1986-08-26 Hans Bundgaard carboxylic acid derivatives
SE466134B (en) * 1990-11-22 1992-01-07 Kabi Pharmacia Ab GEL-PHARMACEUTICAL LIQUID COMPOSITION AND APPLICATION THEREOF IN PHARMACEUTICAL COMPOSITIONS
IT1250421B (en) * 1991-05-30 1995-04-07 Recordati Chem Pharm CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION WITH BIO-ADHESIVE PROPERTIES.
IT1255895B (en) * 1992-10-20 1995-11-17 Laura Chiodini PHARMACEUTICAL COMPOSITIONS CONTAINING A CALCITONIN
US5635210A (en) * 1994-02-03 1997-06-03 The Board Of Regents Of The University Of Oklahoma Method of making a rapidly dissolving tablet
US5472713A (en) * 1994-11-23 1995-12-05 Elf Resources, Inc. Therapeutic uses of emu oil
GB9624563D0 (en) * 1996-11-27 1997-01-15 Smithkline Beecham Plc Product
US6423345B2 (en) * 1998-04-30 2002-07-23 Acusphere, Inc. Matrices formed of polymer and hydrophobic compounds for use in drug delivery
WO2000008001A1 (en) * 1998-08-07 2000-02-17 Chiron Corporation Substituted isoxazole as estrogen receptor modulators
US6426090B1 (en) * 1999-04-06 2002-07-30 Wm. Wrigley Jr. Company Over-coated product including tableted center and medicament
US6375963B1 (en) * 1999-06-16 2002-04-23 Michael A. Repka Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof
DE19927688A1 (en) * 1999-06-17 2000-12-21 Gruenenthal Gmbh Multi-layered tablet containing tramadole and diclofenac, useful for treating pain, has separating layer between active ingredient layers
US6264626B1 (en) * 1999-06-25 2001-07-24 Mcneil-Ppc, Inc. Paperboard applicators having improved gripping features
PL197779B1 (en) * 1999-11-17 2008-04-30 Reckitt Benckiser Uk Ltd Injection−moulded water−soluble container
IL137559A (en) * 2000-07-27 2006-12-31 Amnon Sintov Transdermal drug delivery system
US6495154B1 (en) * 2000-11-21 2002-12-17 Vivus Inc. On demand administration of clomipramine and salts thereof to treat premature ejaculation
US20040253310A1 (en) * 2001-09-21 2004-12-16 Gina Fischer Morphine polymer release system
US6830564B2 (en) * 2002-01-24 2004-12-14 Robin Scott Gray Syringe and method of using
WO2003086297A2 (en) * 2002-04-08 2003-10-23 Lavipharm Laboratories, Inc. Multi-layer mucoadhesive drug delivery device with bursting release layer
AU2003296954A1 (en) * 2002-12-13 2004-07-09 The Regents Of The University Of California Analgesic combination comprising nalbuphine
US7544371B2 (en) * 2005-12-20 2009-06-09 Bausch + Lomb Incorporated Drug delivery systems

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405597A (en) * 1981-02-24 1983-09-20 Shin-Etsu Chemical Co., Ltd. Medicament capsules for rectal application
WO1991003099A1 (en) * 1985-05-01 1991-03-07 Anesta Corporation Compressed powder medicaments
WO1990003776A1 (en) * 1988-10-14 1990-04-19 Zetachron, Inc. Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith
GB2314024A (en) * 1996-06-13 1997-12-17 American Home Prod A novel suppository
WO2001089473A1 (en) * 2000-05-26 2001-11-29 Nycomed Austria Gmbh Pharmaceutical compositions comprising desglymidodrine as an active drug substance

Also Published As

Publication number Publication date
US20050101936A1 (en) 2005-05-12
WO2005046640A2 (en) 2005-05-26
US8157788B2 (en) 2012-04-17
JP2007510663A (en) 2007-04-26
CA2543815A1 (en) 2005-05-26
EP1680081A2 (en) 2006-07-19

Similar Documents

Publication Publication Date Title
WO2005046640A3 (en) Multi-site drug delivery platform
EP2322146A3 (en) Microcapsule formulations comprising two pharmaceutically active ingredients
WO2003047519A3 (en) 'compressed annular tablet with molded triturate tablet for oral and intraoral'
WO2002011711A3 (en) Formulations of mometasone and a bronchodilator for pulmonary administration
WO2007009806A3 (en) Solid dosage formulations of narcotic drugs having improved buccal adsorption
WO2006017505A3 (en) Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
HUP0302319A3 (en) Pharmaceutical composition for oral administration of active ingredient
WO2007079082A3 (en) Gastric release pulse system for drug delivery
WO2007047948A3 (en) Intranasal administration of rapid acting insulin
RS50937B (en) Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-ii diabetes mellitus
AU1079701A (en) Oral transmucosal drug dosage using solid solution
EP2258362A3 (en) Titration dosing regimen for controlled release tramadol
ATE387430T1 (en) COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE INGREDIENTS
WO2002024166A1 (en) Oral preparations with favorable disintegration characteristics
BRPI0406911A (en) Pharmaceutical and / or cosmetic product
HUP0500846A3 (en) Pharmaceutical formulation with an insoluble active agent for pulmonary administration
NO20043871L (en) Controlled release drug formulations containing a carrier peptide
WO2001082897A3 (en) Liposome drug delivery
WO2004108162A3 (en) Controlled release pharmaceutical composition
AU2001296865A1 (en) (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
EP1787638A4 (en) Butylbenzene phthalein self-emulsifying drug delivery system, its preparation method and application
IL159217A0 (en) An oral pharmaceutical formulation comprising a basic pharmaceutically active ingredient having ph-dependent solubility, a process for the manufacture thereof and use thereof in medicine
IL173847A0 (en) Pharmaceutical composition in a form of anhydrous self-nanoemulsifying oily formulation for the administration of poorly water-soluble drugs
WO2001041742A3 (en) Antiviral medication
WO2006060325A3 (en) Coated drug delivery formulations

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2543815

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2004810400

Country of ref document: EP

Ref document number: 2006538507

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: PA/a/2006/005158

Country of ref document: MX

WWP Wipo information: published in national office

Ref document number: 2004810400

Country of ref document: EP