WO2005046441A3 - Method of adapting in-vitro models to aid in noninvasive glucose determination - Google Patents

Method of adapting in-vitro models to aid in noninvasive glucose determination Download PDF

Info

Publication number
WO2005046441A3
WO2005046441A3 PCT/US2004/036992 US2004036992W WO2005046441A3 WO 2005046441 A3 WO2005046441 A3 WO 2005046441A3 US 2004036992 W US2004036992 W US 2004036992W WO 2005046441 A3 WO2005046441 A3 WO 2005046441A3
Authority
WO
WIPO (PCT)
Prior art keywords
noninvasive
glucose concentration
analyzer
aid
vitro
Prior art date
Application number
PCT/US2004/036992
Other languages
French (fr)
Other versions
WO2005046441A2 (en
Inventor
Timothy L Ruchti
Alexander D Lorenz
Original Assignee
Sensys Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/820,322 external-priority patent/US7299080B2/en
Priority claimed from US10/971,447 external-priority patent/US20050107676A1/en
Application filed by Sensys Medical Inc filed Critical Sensys Medical Inc
Publication of WO2005046441A2 publication Critical patent/WO2005046441A2/en
Publication of WO2005046441A3 publication Critical patent/WO2005046441A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
    • A61B2560/0228—Operational features of calibration, e.g. protocols for calibrating sensors using calibration standards
    • A61B2560/0233—Optical standards

Abstract

The invention relates to a noninvasive analyzer and a method of using information determined at least in part from in-vitro spectra of tissue phantoms or analyte solutions to aid in the development of a noninvasive glucose concentration analyzer and/or in the analysis of noninvasive spectra resulting in glucose concentration estimations in the body. The preferred apparatus is a spectrometer that includes a base module and a sample module that is semi­continuously in contact with a human subject and that collects spectral measurements which are used to determine a biological parameter in the sampled tissue, such as glucose concentration. Collection of in-vitro samples is, optionally, performed on a separate instrument from the production model allowing the measurement technology to be developed on a research grade instrument and used or transferred to a target product platform or production analyzer for noninvasive glucose concentration estimation.
PCT/US2004/036992 2003-11-06 2004-11-04 Method of adapting in-vitro models to aid in noninvasive glucose determination WO2005046441A2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US51813603P 2003-11-06 2003-11-06
US60/518,136 2003-11-06
US53260203P 2003-12-23 2003-12-23
US60/532,602 2003-12-23
US10/820,322 US7299080B2 (en) 1999-10-08 2004-04-07 Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy
US10/820,322 2004-04-07
US10/971,447 US20050107676A1 (en) 2003-03-07 2004-10-21 Method and apparatus for noninvasive glucose concentration estimation through near-infrared spectroscopy
US10/971,447 2004-10-21

Publications (2)

Publication Number Publication Date
WO2005046441A2 WO2005046441A2 (en) 2005-05-26
WO2005046441A3 true WO2005046441A3 (en) 2006-03-30

Family

ID=34623775

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/036992 WO2005046441A2 (en) 2003-11-06 2004-11-04 Method of adapting in-vitro models to aid in noninvasive glucose determination

Country Status (1)

Country Link
WO (1) WO2005046441A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5068536A (en) * 1989-01-19 1991-11-26 Futrex, Inc. Method for providing custom calibration for near infrared instruments for measurement of blood glucose
US5507288A (en) * 1994-05-05 1996-04-16 Boehringer Mannheim Gmbh Analytical system for monitoring a substance to be analyzed in patient-blood

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5068536A (en) * 1989-01-19 1991-11-26 Futrex, Inc. Method for providing custom calibration for near infrared instruments for measurement of blood glucose
US5507288A (en) * 1994-05-05 1996-04-16 Boehringer Mannheim Gmbh Analytical system for monitoring a substance to be analyzed in patient-blood
US5507288B1 (en) * 1994-05-05 1997-07-08 Boehringer Mannheim Gmbh Analytical system for monitoring a substance to be analyzed in patient-blood

Also Published As

Publication number Publication date
WO2005046441A2 (en) 2005-05-26

Similar Documents

Publication Publication Date Title
ATE332667T1 (en) METHOD AND DEVICE FOR COLLECTING PHYSIOLOGICAL SAMPLES
Heise et al. Noninvasive blood glucose sensors based on near‐infrared spectroscopy
ATE369070T1 (en) CLASSIFICATION AND CHARACTERIZATION OF TISSUES BY CHARACTERISTICS RELATED TO OBESIC TISSUE
WO2001084122A3 (en) Methods and apparatus for spectroscopic calibration model transfer
HK1057159A1 (en) Physiological sample collection devices
MXPA04008713A (en) Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy.
WO2004081524A3 (en) Measurement site dependent data preprocessing method for robust calibration and prediction
WO2003010510A3 (en) Adjunct quantitative system and method for non-invasive measurement of in vivo analytes
EP2177895A3 (en) Method and apparatus for detection of multiple analytes
WO2003087759A3 (en) Non-invasive spectroscopic measurement of analytes using a matched reference analyte
WO2001060246A3 (en) Multivariate analysis of green to ultraviolet spectra of cell and tissue samples
EP1738689A3 (en) System and method for non-invasive glucose monitoring
WO2005012553A3 (en) Optical in vivo probe of analyte concentration within the sterile matrix under the human nail
PL355356A1 (en) Method of taking a physiological sample as well as skin puncturing element, test strip and apparatus for determining concentration of analyte in a physiological sample
CA2347040A1 (en) Method for non-invasive blood analyte measurement with improved optical interface
DE60238914D1 (en) INTEGRATED BLOOD SAMPLE ANALYSIS SYSTEM WITH MULTI-USE SAMPLING MODULE
WO2008014132A3 (en) Combination analyte measurement device and method of use
SG125086A1 (en) Continuous strip of fluid sampling and testing devices and methods of making, packaging and using the same
CA2481981A1 (en) A non-invasive blood constituent measuring instrument and measuring method
WO2000013002A3 (en) Reagentless analysis of biological samples
WO2005054811A3 (en) Method and apparatus for ultrasonic determination of hematocrit and hemoglobin concentrations
WO2006113476A3 (en) Non-invasive system for measuring glucose in the body
DE60315373D1 (en) Apparatus and method for determining the concentration of analytes
ATE550642T1 (en) METHOD FOR MEASURING 1,5-ANHYDROGLUCITOL IN WHOLE BLOOD
ATE490729T1 (en) DEVICE FOR MEASURING AN ANALYTE IN A BODY FLUID

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
122 Ep: pct application non-entry in european phase