WO2005042703A3 - Placental stem cells and uses thereof - Google Patents

Placental stem cells and uses thereof Download PDF

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Publication number
WO2005042703A3
WO2005042703A3 PCT/US2004/034966 US2004034966W WO2005042703A3 WO 2005042703 A3 WO2005042703 A3 WO 2005042703A3 US 2004034966 W US2004034966 W US 2004034966W WO 2005042703 A3 WO2005042703 A3 WO 2005042703A3
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WIPO (PCT)
Prior art keywords
placental stem
stem cells
cells
cardiomyocytes
hepatocytes
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PCT/US2004/034966
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French (fr)
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WO2005042703A2 (en
Inventor
Stephen C Strom
Miki Toshio
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M Of Higher Education Universi
Stephen C Strom
Miki Toshio
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Publication date
Application filed by M Of Higher Education Universi, Stephen C Strom, Miki Toshio filed Critical M Of Higher Education Universi
Priority to CA002543528A priority Critical patent/CA2543528A1/en
Priority to EP04796030A priority patent/EP1689854A4/en
Publication of WO2005042703A2 publication Critical patent/WO2005042703A2/en
Publication of WO2005042703A3 publication Critical patent/WO2005042703A3/en

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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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Abstract

The present invention features novel placental stem cells and provides methods and compositions for the therapeutic uses of placental stem cells or placental stem cells that have been induced to differentiate into a desired tissue type into a recipient host in amounts sufficient to result in production of the desired cell type, e.g., hepatocytes, neural cells, pancreatic cells, vascular endothelial cells, cardiomyocytes.
PCT/US2004/034966 2003-10-22 2004-10-22 Placental stem cells and uses thereof WO2005042703A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002543528A CA2543528A1 (en) 2003-10-22 2004-10-22 Placental stem cells and uses thereof
EP04796030A EP1689854A4 (en) 2003-10-22 2004-10-22 Placental stem cells and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/691,468 US20040161419A1 (en) 2002-04-19 2003-10-22 Placental stem cells and uses thereof
US10/691,468 2003-10-22

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WO2005042703A2 WO2005042703A2 (en) 2005-05-12
WO2005042703A3 true WO2005042703A3 (en) 2006-06-22

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US (1) US20040161419A1 (en)
EP (1) EP1689854A4 (en)
CA (1) CA2543528A1 (en)
WO (1) WO2005042703A2 (en)

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US8916146B2 (en) 2007-02-12 2014-12-23 Anthrogenesis Corporation Treatment of inflammatory diseases using placental stem cells
US8926964B2 (en) 2010-07-13 2015-01-06 Anthrogenesis Corporation Methods of generating natural killer cells
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
US9121007B2 (en) 2010-01-26 2015-09-01 Anthrogenesis Corporatin Treatment of bone-related cancers using placental stem cells
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
US9139813B2 (en) 2001-02-14 2015-09-22 Anthrogenesis Corporation Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
US9149569B2 (en) 2000-12-06 2015-10-06 Anthrogenesis Corporation Treatment of diseases or disorders using placental stem cells
US9175261B2 (en) 2005-12-16 2015-11-03 DePuy Synthes Products, Inc. Human umbilical cord tissue cells for inhibiting adverse immune response in histocompatibility-mismatched transplantation
US9198938B2 (en) 2008-11-19 2015-12-01 Antrhogenesis Corporation Amnion derived adherent cells
US9216200B2 (en) 2007-09-28 2015-12-22 Anthrogenesis Corporation Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
US9234172B2 (en) 2003-06-27 2016-01-12 DePuy Synthes Products, Inc. Repair and regeneration of ocular tissue using postpartum-derived cells
US9254302B2 (en) 2010-04-07 2016-02-09 Anthrogenesis Corporation Angiogenesis using placental stem cells
US9498501B2 (en) 2003-06-27 2016-11-22 DePuy Synthes Products, Inc. Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells

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US7875272B2 (en) 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
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US7993918B2 (en) * 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
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