WO2005024068A3 - Allele-specific sequence variation analysis - Google Patents

Allele-specific sequence variation analysis Download PDF

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Publication number
WO2005024068A3
WO2005024068A3 PCT/US2004/028997 US2004028997W WO2005024068A3 WO 2005024068 A3 WO2005024068 A3 WO 2005024068A3 US 2004028997 W US2004028997 W US 2004028997W WO 2005024068 A3 WO2005024068 A3 WO 2005024068A3
Authority
WO
WIPO (PCT)
Prior art keywords
allele
specific sequence
sequence variation
variation analysis
systems
Prior art date
Application number
PCT/US2004/028997
Other languages
French (fr)
Other versions
WO2005024068A2 (en
Inventor
Martin Beaulieu
Den Boom Dirk Van
Original Assignee
Sequenom Inc
Martin Beaulieu
Den Boom Dirk Van
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sequenom Inc, Martin Beaulieu, Den Boom Dirk Van filed Critical Sequenom Inc
Publication of WO2005024068A2 publication Critical patent/WO2005024068A2/en
Publication of WO2005024068A3 publication Critical patent/WO2005024068A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Abstract

Fragmentation-based methods and systems, particularly mass spectrometry based methods and systems, for the analysis of sequence variations including haplotypes are provided. Also provided are methods for obtaining a specific allele from a nucleic acid mixture, such as genomic DNA.
PCT/US2004/028997 2003-09-05 2004-09-02 Allele-specific sequence variation analysis WO2005024068A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50048903P 2003-09-05 2003-09-05
US60/500,489 2003-09-05

Publications (2)

Publication Number Publication Date
WO2005024068A2 WO2005024068A2 (en) 2005-03-17
WO2005024068A3 true WO2005024068A3 (en) 2005-09-22

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Family Applications (1)

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PCT/US2004/028997 WO2005024068A2 (en) 2003-09-05 2004-09-02 Allele-specific sequence variation analysis

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US (1) US9394565B2 (en)
WO (1) WO2005024068A2 (en)

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