WO2005018600A3 - Method of treating a patient suffering from a solid tumour - Google Patents

Method of treating a patient suffering from a solid tumour Download PDF

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Publication number
WO2005018600A3
WO2005018600A3 PCT/DK2004/000560 DK2004000560W WO2005018600A3 WO 2005018600 A3 WO2005018600 A3 WO 2005018600A3 DK 2004000560 W DK2004000560 W DK 2004000560W WO 2005018600 A3 WO2005018600 A3 WO 2005018600A3
Authority
WO
WIPO (PCT)
Prior art keywords
tumour
patient suffering
treating
particles
solid tumour
Prior art date
Application number
PCT/DK2004/000560
Other languages
French (fr)
Other versions
WO2005018600A2 (en
Inventor
Erik Andersen
Original Assignee
Cube Medical As
Erik Andersen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cube Medical As, Erik Andersen filed Critical Cube Medical As
Publication of WO2005018600A2 publication Critical patent/WO2005018600A2/en
Publication of WO2005018600A3 publication Critical patent/WO2005018600A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules

Abstract

Disclosed is treatment of a patient suffering from a solid tumour, where microparticles are administered which have a diametrical size that results in retention of the particles in the tumour's arterioles, so as to release a chemotherapeutical agent to the surrounding tumour tissue while minimally compromising surrounding non-tumour tissue. Preferred embodiments entail that encapsulating microspheres are rendered leaky for the chemotherapeutic agent by means of an electromagnetic or ultrasound shock wave. Other embodiments comprise co-administration to the patient of at least one therapeutic agent comprised in particles to provide an anti-inflammatory effect or inhibition of cell death.
PCT/DK2004/000560 2003-08-22 2004-08-23 Method of treating a patient suffering from a solid tumour WO2005018600A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49690903P 2003-08-22 2003-08-22
DKPA200301204 2003-08-22
US60/496,909 2003-08-22
DKPA200301204 2003-08-22

Publications (2)

Publication Number Publication Date
WO2005018600A2 WO2005018600A2 (en) 2005-03-03
WO2005018600A3 true WO2005018600A3 (en) 2005-05-12

Family

ID=34219532

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2004/000560 WO2005018600A2 (en) 2003-08-22 2004-08-23 Method of treating a patient suffering from a solid tumour

Country Status (1)

Country Link
WO (1) WO2005018600A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9034031B2 (en) 2009-08-07 2015-05-19 Zeus Industrial Products, Inc. Prosthetic device including electrostatically spun fibrous layer and method for making the same

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US7470240B2 (en) 2004-10-22 2008-12-30 General Patent, Llc Pressure pulse/shock wave therapy methods and an apparatus for conducting the therapeutic methods
US7507213B2 (en) 2004-03-16 2009-03-24 General Patent Llc Pressure pulse/shock wave therapy methods for organs
US7601127B2 (en) 2004-10-22 2009-10-13 General Patent, Llc Therapeutic stimulation of genital tissue or reproductive organ of an infertility or impotence diagnosed patient
US7537572B2 (en) 2004-10-22 2009-05-26 General Patent, Llc Treatment or pre-treatment for radiation/chemical exposure
US7544171B2 (en) 2004-10-22 2009-06-09 General Patent Llc Methods for promoting nerve regeneration and neuronal growth and elongation
US7497836B2 (en) 2004-10-22 2009-03-03 General Patent Llc Germicidal method for treating or preventing sinusitis
US7578796B2 (en) 2004-10-22 2009-08-25 General Patent Llc Method of shockwave treating fish and shellfish
US7497834B2 (en) 2004-10-22 2009-03-03 General Patent Llc Germicidal method for eradicating or preventing the formation of biofilms
US7497835B2 (en) 2004-10-22 2009-03-03 General Patent Llc Method of treatment for and prevention of periodontal disease
US7600343B2 (en) 2004-10-22 2009-10-13 General Patent, Llc Method of stimulating plant growth
EP1741463A1 (en) 2005-07-05 2007-01-10 Millimed A/S A guiding and an embolization catheter
EP2384375B1 (en) 2009-01-16 2017-07-05 Zeus Industrial Products, Inc. Electrospinning of ptfe with high viscosity materials
US20130268062A1 (en) 2012-04-05 2013-10-10 Zeus Industrial Products, Inc. Composite prosthetic devices
CN103561682A (en) 2011-01-28 2014-02-05 梅瑞特医药体系股份有限公司 Electrospun PTFE coated stent and method of use
EP2804637B1 (en) 2012-01-16 2019-09-25 Merit Medical Systems, Inc. Rotational spun material covered medical appliances and methods of manufacture
US11541154B2 (en) 2012-09-19 2023-01-03 Merit Medical Systems, Inc. Electrospun material covered medical appliances and methods of manufacture
US9198999B2 (en) * 2012-09-21 2015-12-01 Merit Medical Systems, Inc. Drug-eluting rotational spun coatings and methods of use
EP2967929B1 (en) 2013-03-13 2017-11-29 Merit Medical Systems, Inc. Methods, systems, and apparatuses for manufacturing rotational spun appliances
EP2971320B1 (en) 2013-03-13 2021-09-29 Merit Medical Systems, Inc. Serially deposited fiber materials and associated devices and methods
US9784730B2 (en) 2013-03-21 2017-10-10 University Of Washington Through Its Center For Commercialization Nanoparticle for targeting brain tumors and delivery of O6-benzylguanine
WO2016138221A1 (en) 2015-02-26 2016-09-01 Merit Medical Systems, Inc. Layered medical appliances and methods
EP3373907A4 (en) * 2015-11-11 2019-12-18 Qrono, Inc. Sustained release pharmaceutical compositions and methods of use
US11389372B2 (en) 2016-04-18 2022-07-19 Softwave Tissue Regeneration Technologies, Llc Acoustic shock wave therapeutic methods
US11389371B2 (en) 2018-05-21 2022-07-19 Softwave Tissue Regeneration Technologies, Llc Acoustic shock wave therapeutic methods
US11389373B2 (en) 2016-04-18 2022-07-19 Softwave Tissue Regeneration Technologies, Llc Acoustic shock wave therapeutic methods to prevent or treat opioid addiction
US11458069B2 (en) 2016-04-18 2022-10-04 Softwave Tissue Regeneration Technologies, Llc Acoustic shock wave therapeutic methods to treat medical conditions using reflexology zones

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238714A (en) * 1990-10-02 1993-08-24 Board Of Regents, The University Of Texas System Efficient microcapsule preparation and method of use
US5470582A (en) * 1992-02-07 1995-11-28 Syntex (U.S.A.) Inc. Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
WO2000023054A1 (en) * 1998-10-16 2000-04-27 Biosphere Medical, S.A. Polyvinyl alcohol microspheres, and methods for making and therapeutic uses of the same
WO2000066183A1 (en) * 1999-05-03 2000-11-09 Lee, Kyu-Ho Vascular embolic materials having multifunctions
EP1155689A2 (en) * 1993-07-19 2001-11-21 Angiotech Pharmaceuticals, Inc. Anti-angiogenic compositions and methods of use
WO2002000192A2 (en) * 2000-06-23 2002-01-03 Carbon Medical Technologies, Inc. Embolization using carbon coated particles
WO2002003955A1 (en) * 2000-07-10 2002-01-17 F.T. Holding S.A. Fast release bioadhesive microspheres for the sublingual administration of proximate principles
WO2002051388A2 (en) * 2000-12-22 2002-07-04 Ethypharm Treatment of inoperable tumors by stereotactic injection of microspheres
WO2003094930A1 (en) * 2002-05-08 2003-11-20 Biosphere Medical, Inc. Embolization using degradable crosslinked hydrogels

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238714A (en) * 1990-10-02 1993-08-24 Board Of Regents, The University Of Texas System Efficient microcapsule preparation and method of use
US5470582A (en) * 1992-02-07 1995-11-28 Syntex (U.S.A.) Inc. Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
EP1155689A2 (en) * 1993-07-19 2001-11-21 Angiotech Pharmaceuticals, Inc. Anti-angiogenic compositions and methods of use
WO2000023054A1 (en) * 1998-10-16 2000-04-27 Biosphere Medical, S.A. Polyvinyl alcohol microspheres, and methods for making and therapeutic uses of the same
WO2000066183A1 (en) * 1999-05-03 2000-11-09 Lee, Kyu-Ho Vascular embolic materials having multifunctions
WO2002000192A2 (en) * 2000-06-23 2002-01-03 Carbon Medical Technologies, Inc. Embolization using carbon coated particles
WO2002003955A1 (en) * 2000-07-10 2002-01-17 F.T. Holding S.A. Fast release bioadhesive microspheres for the sublingual administration of proximate principles
WO2002051388A2 (en) * 2000-12-22 2002-07-04 Ethypharm Treatment of inoperable tumors by stereotactic injection of microspheres
WO2003094930A1 (en) * 2002-05-08 2003-11-20 Biosphere Medical, Inc. Embolization using degradable crosslinked hydrogels

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9034031B2 (en) 2009-08-07 2015-05-19 Zeus Industrial Products, Inc. Prosthetic device including electrostatically spun fibrous layer and method for making the same

Also Published As

Publication number Publication date
WO2005018600A2 (en) 2005-03-03

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