WO2005000235A3 - NUCLEIC ACID SEQUENCES ENCODING AND COMPOSITIONS COMPRISING IgE SIGNAL PEPTIDE AND/OR IL-15 AND METHODS FOR USING THE SAME - Google Patents
NUCLEIC ACID SEQUENCES ENCODING AND COMPOSITIONS COMPRISING IgE SIGNAL PEPTIDE AND/OR IL-15 AND METHODS FOR USING THE SAME Download PDFInfo
- Publication number
- WO2005000235A3 WO2005000235A3 PCT/US2004/018962 US2004018962W WO2005000235A3 WO 2005000235 A3 WO2005000235 A3 WO 2005000235A3 US 2004018962 W US2004018962 W US 2004018962W WO 2005000235 A3 WO2005000235 A3 WO 2005000235A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acid
- compositions
- disclosed
- methods
- signal peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5443—IL-15
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Abstract
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006533791A JP2007516696A (en) | 2003-06-13 | 2004-06-14 | Nucleic acid sequences encoding IgE signal peptide and / or IL-15, compositions comprising them and methods of use thereof |
AU2004251070A AU2004251070B2 (en) | 2003-06-13 | 2004-06-14 | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
MXPA05013526A MXPA05013526A (en) | 2003-06-13 | 2004-06-14 | NUCLEIC ACID SEQUENCES ENCODING AND COMPOSITIONS COMPRISING IgE SIGNAL PEPTIDE AND/OR IL-15 AND METHODS FOR USING THE SAME. |
EP04776577.1A EP1638987B1 (en) | 2003-06-13 | 2004-06-14 | NUCLEIC ACID SEQUENCES ENCODING AND COMPOSITIONS COMPRISING IgE SIGNAL PEPTIDE AND/OR IL-15 AND METHODS FOR USING THE SAME |
US10/560,650 US8173786B2 (en) | 2003-06-13 | 2004-06-14 | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
BRPI0411363-2A BRPI0411363A (en) | 2003-06-13 | 2004-06-14 | nucleic acid sequences encoding and compositions comprising signal peptide ige and / or il-15 and processes for use thereof |
NZ544077A NZ544077A (en) | 2003-06-13 | 2004-06-14 | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
KR1020117023822A KR101225473B1 (en) | 2003-06-13 | 2004-06-14 | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
KR1020057023994A KR101269548B1 (en) | 2003-06-13 | 2004-06-14 | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
CN2004800228915A CN1832956B (en) | 2003-06-13 | 2004-06-14 | Nucleic acid sequences encoding and compositions comprising ige signal peptide and/or il-15 and methods for using the same |
CA2529145A CA2529145C (en) | 2003-06-13 | 2004-06-14 | Nucleic acid sequences encoding and compositions comprising ige signal peptide and/or il-15 and methods for using the same |
IL172496A IL172496A (en) | 2003-06-13 | 2005-12-11 | NUCLEIC ACID SEQUENCES ENCODING AND COMPOSITIONS COMPRISING IgE SIGNAL PEPTIDE AND/OR IL-15 AND METHODS FOR USING THE SAME |
US13/466,015 US20120276142A1 (en) | 2003-06-13 | 2012-05-07 | Nucleic acid sequences encoding and compositions comprising ige signal peptide and/or il-15 and methods for using the same |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47820503P | 2003-06-13 | 2003-06-13 | |
US47821003P | 2003-06-13 | 2003-06-13 | |
US60/478,210 | 2003-06-13 | ||
US60/478,205 | 2003-06-13 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/466,015 Division US20120276142A1 (en) | 2003-06-13 | 2012-05-07 | Nucleic acid sequences encoding and compositions comprising ige signal peptide and/or il-15 and methods for using the same |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005000235A2 WO2005000235A2 (en) | 2005-01-06 |
WO2005000235A3 true WO2005000235A3 (en) | 2005-06-16 |
Family
ID=33555491
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/018962 WO2005000235A2 (en) | 2003-06-13 | 2004-06-14 | NUCLEIC ACID SEQUENCES ENCODING AND COMPOSITIONS COMPRISING IgE SIGNAL PEPTIDE AND/OR IL-15 AND METHODS FOR USING THE SAME |
Country Status (12)
Country | Link |
---|---|
US (2) | US8173786B2 (en) |
EP (2) | EP2292634A3 (en) |
JP (2) | JP2007516696A (en) |
KR (2) | KR101225473B1 (en) |
CN (1) | CN1832956B (en) |
AU (2) | AU2004251070B2 (en) |
BR (1) | BRPI0411363A (en) |
CA (1) | CA2529145C (en) |
IL (1) | IL172496A (en) |
MX (1) | MXPA05013526A (en) |
NZ (2) | NZ570709A (en) |
WO (1) | WO2005000235A2 (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
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NZ570709A (en) * | 2003-06-13 | 2010-04-30 | Univ Pennsylvania | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
AU2007208452B2 (en) * | 2006-01-13 | 2012-07-05 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using codon optimized IL-15 and methods for using the same |
KR101999376B1 (en) | 2006-07-28 | 2019-07-11 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | Improved vaccines and methods for using the same |
US10426827B1 (en) * | 2006-11-06 | 2019-10-01 | Microvax, Llc | Dengue hemorrhagic fever virus vaccine |
AU2009210624A1 (en) * | 2008-01-11 | 2009-08-13 | Vgx Pharmaceuticals, Inc. | Novel vaccines against multiple subtypes of dengue virus |
US10071154B2 (en) * | 2008-04-04 | 2018-09-11 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using IL-28 and compositions and methods of using the same |
WO2009124312A2 (en) * | 2008-04-04 | 2009-10-08 | The Trustees Of The University Of Pennsylvania | Consensus sequences of chikungunya viral proteins, nucleic acid molecules encoding the same, and compositions and methods for using the same |
CA2771334A1 (en) | 2009-09-14 | 2011-03-17 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics comprising il-15 receptor alpha and/or nucleic acid molecules encoding the same, and methods for using the same |
WO2011097640A1 (en) * | 2010-02-08 | 2011-08-11 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same |
PL2672992T3 (en) | 2011-02-11 | 2020-11-02 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecule encoding hepatitis b virus core protein and vaccine comprising the same |
US9238679B2 (en) | 2011-02-11 | 2016-01-19 | The Trustees Of The University Of Pennslyvania | Nucleic acid molecule encoding hepatitis B virus core protein and surface antigen protein and vaccine comprising the same |
CA2858884A1 (en) | 2011-12-12 | 2013-06-20 | The Trustees Of The University Of Pennsylvania | Proteins comprising mrsa pbp2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat mrsa infections |
JP2015514132A (en) * | 2012-04-10 | 2015-05-18 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Human respiratory syncytial virus consensus antigens, nucleic acid constructs, vaccines made therefrom, and methods of use thereof |
KR20240010758A (en) * | 2012-04-12 | 2024-01-24 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same |
WO2014186469A2 (en) * | 2013-05-14 | 2014-11-20 | Board Of Regents, The University Of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
KR102586707B1 (en) * | 2014-10-01 | 2023-10-11 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | Vaccines having an antigen and interleukin-21 as an adjuvant |
AU2016341311B2 (en) * | 2015-10-22 | 2023-11-16 | Modernatx, Inc. | Respiratory syncytial virus vaccine |
EA201892124A1 (en) | 2016-12-02 | 2019-04-30 | Дэвид Б. Уэйнер | DNA STRUCTURES OF ANTIBODIES AND METHODS OF THEIR APPLICATION |
CU24546B1 (en) * | 2016-12-30 | 2021-09-07 | Ct Ingenieria Genetica Biotecnologia | VACCINAL COMPOSITION INCLUDING A HUMAN INTERLEUKIN-15 MUTANT |
JP7288401B2 (en) | 2017-01-10 | 2023-06-07 | プレシゲン,インコーポレイテッド | Modulation of polypeptide expression via a novel gene switch expression system |
AU2020345943A1 (en) | 2019-09-10 | 2022-03-31 | Obsidian Therapeutics, Inc. | CA2-IL15 fusion proteins for tunable regulation |
US20220133885A1 (en) * | 2020-11-02 | 2022-05-05 | Drexel University | Compositions and methods employing adenosine deaminase-1 (ada-1) as an adjuvant |
EP4329786A1 (en) * | 2021-04-30 | 2024-03-06 | KaliVir Immunotherapeutics, Inc. | Oncolytic viruses for modified mhc expression |
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US20020123099A1 (en) * | 2000-10-04 | 2002-09-05 | Weiner David B. | Highly expressible genes |
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NZ570709A (en) * | 2003-06-13 | 2010-04-30 | Univ Pennsylvania | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
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-
2004
- 2004-06-13 NZ NZ570709A patent/NZ570709A/en not_active IP Right Cessation
- 2004-06-14 WO PCT/US2004/018962 patent/WO2005000235A2/en active Application Filing
- 2004-06-14 AU AU2004251070A patent/AU2004251070B2/en not_active Ceased
- 2004-06-14 KR KR1020117023822A patent/KR101225473B1/en active IP Right Grant
- 2004-06-14 US US10/560,650 patent/US8173786B2/en not_active Expired - Fee Related
- 2004-06-14 BR BRPI0411363-2A patent/BRPI0411363A/en not_active Application Discontinuation
- 2004-06-14 CA CA2529145A patent/CA2529145C/en not_active Expired - Fee Related
- 2004-06-14 KR KR1020057023994A patent/KR101269548B1/en active IP Right Grant
- 2004-06-14 CN CN2004800228915A patent/CN1832956B/en not_active Expired - Fee Related
- 2004-06-14 NZ NZ544077A patent/NZ544077A/en not_active IP Right Cessation
- 2004-06-14 EP EP10191165A patent/EP2292634A3/en not_active Withdrawn
- 2004-06-14 MX MXPA05013526A patent/MXPA05013526A/en active IP Right Grant
- 2004-06-14 EP EP04776577.1A patent/EP1638987B1/en not_active Not-in-force
- 2004-06-14 JP JP2006533791A patent/JP2007516696A/en active Pending
-
2005
- 2005-12-11 IL IL172496A patent/IL172496A/en active IP Right Grant
-
2012
- 2012-02-14 JP JP2012029973A patent/JP5623444B2/en not_active Expired - Fee Related
- 2012-05-07 US US13/466,015 patent/US20120276142A1/en not_active Abandoned
- 2012-05-16 AU AU2012202867A patent/AU2012202867B2/en not_active Ceased
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020123099A1 (en) * | 2000-10-04 | 2002-09-05 | Weiner David B. | Highly expressible genes |
Non-Patent Citations (3)
Title |
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ANETHER ET AL: "Interleukin-15 as a potential costimulatory cytokine in CD154 gene therapy of chronic lymphocytic leukemia", BLOOD, vol. 99, pages 722 - 723, XP002987799 * |
RUCKERT ET AL: "II-15-IgG2b fusion protein accelerates and enhances a TH2 but not a Th1 immune response in vivo, while IL-2-IgG2b fusion protein inhibits both", EUR. J. IMMUNOL., vol. 28, December 1998 (1998-12-01), pages 3312 - 3320, XP002230807 * |
WIERDA ET AL: "CD40-ligand (CD145) gene therapy for chronic lymphocytic leukemia", BLOOD, vol. 96, November 2000 (2000-11-01), pages 2917 - 2924, XP002987798 * |
Also Published As
Publication number | Publication date |
---|---|
NZ570709A (en) | 2010-04-30 |
EP1638987A4 (en) | 2007-12-26 |
KR20060030041A (en) | 2006-04-07 |
MXPA05013526A (en) | 2006-03-09 |
CN1832956B (en) | 2013-11-20 |
JP2007516696A (en) | 2007-06-28 |
WO2005000235A2 (en) | 2005-01-06 |
EP1638987A2 (en) | 2006-03-29 |
IL172496A0 (en) | 2006-04-10 |
AU2004251070A1 (en) | 2005-01-06 |
KR101269548B1 (en) | 2013-06-21 |
AU2012202867B2 (en) | 2015-01-29 |
JP2012110345A (en) | 2012-06-14 |
CN1832956A (en) | 2006-09-13 |
AU2004251070B2 (en) | 2012-02-23 |
US8173786B2 (en) | 2012-05-08 |
KR101225473B1 (en) | 2013-01-24 |
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EP1638987B1 (en) | 2014-11-19 |
IL172496A (en) | 2013-02-28 |
US20120276142A1 (en) | 2012-11-01 |
BRPI0411363A (en) | 2006-07-25 |
NZ544077A (en) | 2009-01-31 |
AU2012202867A1 (en) | 2012-06-07 |
CA2529145A1 (en) | 2005-01-06 |
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