WO2004105826A3 - Implantate mit funktionalisierten kohlenstoffoberflächen - Google Patents

Implantate mit funktionalisierten kohlenstoffoberflächen Download PDF

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Publication number
WO2004105826A3
WO2004105826A3 PCT/EP2004/005785 EP2004005785W WO2004105826A3 WO 2004105826 A3 WO2004105826 A3 WO 2004105826A3 EP 2004005785 W EP2004005785 W EP 2004005785W WO 2004105826 A3 WO2004105826 A3 WO 2004105826A3
Authority
WO
WIPO (PCT)
Prior art keywords
implants
functionalized carbon
carbon
containing layer
carbon surfaces
Prior art date
Application number
PCT/EP2004/005785
Other languages
English (en)
French (fr)
Other versions
WO2004105826A2 (de
Inventor
Joerg Rathenow
Soheil Asgari
Andreas Ban
Juergen Kunstmann
Bernhard Mayer
Original Assignee
Blue Membranes Gmbh
Joerg Rathenow
Soheil Asgari
Andreas Ban
Juergen Kunstmann
Bernhard Mayer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2003124415 external-priority patent/DE10324415A1/de
Priority claimed from DE10333099A external-priority patent/DE10333099A1/de
Priority claimed from DE2003133098 external-priority patent/DE10333098A1/de
Priority to DK04735213T priority Critical patent/DK1626749T3/da
Priority to EA200501561A priority patent/EA009836B1/ru
Priority to DE502004008211T priority patent/DE502004008211D1/de
Priority to JP2006529943A priority patent/JP2007502184A/ja
Priority to PL04735213T priority patent/PL1626749T3/pl
Priority to DE202004009061U priority patent/DE202004009061U1/de
Priority to CN200480013969A priority patent/CN100594040C/zh
Application filed by Blue Membranes Gmbh, Joerg Rathenow, Soheil Asgari, Andreas Ban, Juergen Kunstmann, Bernhard Mayer filed Critical Blue Membranes Gmbh
Priority to MXPA05011231 priority patent/MXPA05011231A/es
Priority to AU2004243503A priority patent/AU2004243503A1/en
Priority to BRPI0410957-0A priority patent/BRPI0410957A/pt
Priority to SI200431001T priority patent/SI1626749T1/sl
Priority to CA002519750A priority patent/CA2519750A1/en
Priority to EP04735213A priority patent/EP1626749B1/de
Priority to US10/939,021 priority patent/US20050079201A1/en
Publication of WO2004105826A2 publication Critical patent/WO2004105826A2/de
Publication of WO2004105826A3 publication Critical patent/WO2004105826A3/de
Priority to HK06106757.4A priority patent/HK1089702A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/303Carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/082Inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/082Inorganic materials
    • A61L31/084Carbon; Graphite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/18Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment

Abstract

Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung medizinischer Implantate mit funktionalisierten Oberflächen, durch Bereitstellung eines medizinischen Implantats mit mindestens einer kohlenstoffhaltigen Schicht auf mindestens einem Teil der Oberfläche des Implantats, Aktivierung der kohlenstoffhaltigen Schicht durch Schaffung von Porosität, sowie Funktionalisierung der aktivierten, kohlenstoffhaltigen Schicht, und danach erhältliche funktionalisierte Implantate.
PCT/EP2004/005785 2003-05-28 2004-05-28 Implantate mit funktionalisierten kohlenstoffoberflächen WO2004105826A2 (de)

Priority Applications (15)

Application Number Priority Date Filing Date Title
SI200431001T SI1626749T1 (sl) 2003-05-28 2004-05-28 Implantat s funkcionaliziranimi ogljikovimi površinami
CA002519750A CA2519750A1 (en) 2003-05-28 2004-05-28 Implants with functionalized carbon surfaces
EP04735213A EP1626749B1 (de) 2003-05-28 2004-05-28 Implantate mit funktionalisierten kohlenstoffoberflächen
AU2004243503A AU2004243503A1 (en) 2003-05-28 2004-05-28 Implants comprising functionalized carbon surfaces
DE502004008211T DE502004008211D1 (de) 2003-05-28 2004-05-28 Implantate mit funktionalisierten kohlenstoffoberflächen
JP2006529943A JP2007502184A (ja) 2003-05-28 2004-05-28 機能化カーボン表面を有するインプラント
PL04735213T PL1626749T3 (pl) 2003-05-28 2004-05-28 Implanty zawierające sfunkcjonalizowane powierzchnie węglowe
DE202004009061U DE202004009061U1 (de) 2003-05-28 2004-05-28 Implantate mit funktionalisierten Kohlenstoffoberflächen
CN200480013969A CN100594040C (zh) 2003-05-28 2004-05-28 具有功能化的碳表面的植入物
DK04735213T DK1626749T3 (da) 2003-05-28 2004-05-28 Implantater med funktionaliserede carbonoverflader
MXPA05011231 MXPA05011231A (es) 2003-05-28 2004-05-28 Implante con superficies de carbono funcionaliza
EA200501561A EA009836B1 (ru) 2003-05-28 2004-05-28 Имплантаты с функционализированными углеродными поверхностями
BRPI0410957-0A BRPI0410957A (pt) 2003-05-28 2004-05-28 implantes com superfìcies de carbono funcionalizadas
US10/939,021 US20050079201A1 (en) 2003-05-28 2004-09-10 Implants with functionalized carbon surfaces
HK06106757.4A HK1089702A1 (en) 2003-05-28 2006-06-13 Implants comprising functionalized carbon surfaces

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE2003124415 DE10324415A1 (de) 2003-05-28 2003-05-28 Verfahren zur Beschichtung von Substraten mit kohlenstoffbasiertem Material
DE10324415.8 2003-05-28
DE2003133098 DE10333098A1 (de) 2003-07-21 2003-07-21 Biokompatibel beschichtete medizinische Implantate
DE10333099A DE10333099A1 (de) 2003-07-21 2003-07-21 Implantate mit funktionalisierten Kohlenstoffoberflächen
DE10333099.2 2003-07-21
DE10333098.4 2003-07-21

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/939,021 Continuation-In-Part US20050079201A1 (en) 2003-05-28 2004-09-10 Implants with functionalized carbon surfaces

Publications (2)

Publication Number Publication Date
WO2004105826A2 WO2004105826A2 (de) 2004-12-09
WO2004105826A3 true WO2004105826A3 (de) 2005-06-23

Family

ID=32872363

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/005785 WO2004105826A2 (de) 2003-05-28 2004-05-28 Implantate mit funktionalisierten kohlenstoffoberflächen

Country Status (18)

Country Link
US (1) US20050079201A1 (de)
EP (2) EP1626749B1 (de)
JP (1) JP2007502184A (de)
KR (1) KR20060015624A (de)
AT (1) ATE410196T1 (de)
AU (1) AU2004243503A1 (de)
BR (1) BRPI0410957A (de)
CA (1) CA2519750A1 (de)
DE (2) DE202004009061U1 (de)
DK (1) DK1626749T3 (de)
EA (1) EA009836B1 (de)
ES (1) ES2315661T3 (de)
HK (1) HK1089702A1 (de)
MX (1) MXPA05011231A (de)
PL (1) PL1626749T3 (de)
PT (1) PT1626749E (de)
SI (1) SI1626749T1 (de)
WO (1) WO2004105826A2 (de)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040081704A1 (en) * 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7666462B2 (en) * 2001-05-11 2010-02-23 Exogenesis Corporation Method of controlling a drug release rate
US7238478B2 (en) * 2003-11-13 2007-07-03 Stratagene California Compositions and methods for protein isolation
US7737214B2 (en) * 2004-03-15 2010-06-15 Terumo Kabushiki Kaisha Adhesion preventive material
WO2005089480A2 (en) 2004-03-19 2005-09-29 Stuart Arthur Bateman Activation method
AU2005249494A1 (en) * 2004-05-28 2005-12-15 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
EP2111881A1 (de) * 2004-07-05 2009-10-28 Ziscoat N.V. biokompatible Beschichtungen für medizinische vorrichtungen mit Molekularsieben
JP2008511459A (ja) * 2004-09-05 2008-04-17 フリクション コントロール ソリューションズ リミティド. 作業面と作業面を生成するシステムと方法
AT501408B1 (de) * 2004-12-07 2011-03-15 Physikalisches Buero Steinmueller Gmbh Biologische oberflächen
US20060129215A1 (en) * 2004-12-09 2006-06-15 Helmus Michael N Medical devices having nanostructured regions for controlled tissue biocompatibility and drug delivery
US20060127443A1 (en) * 2004-12-09 2006-06-15 Helmus Michael N Medical devices having vapor deposited nanoporous coatings for controlled therapeutic agent delivery
CN101107021A (zh) * 2004-12-30 2008-01-16 金文申有限公司 包含信号提供试剂、植入物材料和药物的组合
JP2008527119A (ja) 2005-01-13 2008-07-24 シンベンション アーゲー 炭素ナノ粒子を含有する複合材料
CA2589526C (en) 2005-01-21 2014-12-02 Commonwealth Scientific And Industrial Research Organisation Activation method using modifying agent
US8057543B2 (en) 2005-01-28 2011-11-15 Greatbatch Ltd. Stent coating for eluting medication
KR20070100836A (ko) * 2005-02-03 2007-10-11 신벤션 아게 졸/겔 기술에 의하여 제조된 약물 전달 물질
CN101142149A (zh) * 2005-03-18 2008-03-12 金文申有限公司 制备多孔烧结金属材料的方法
DE102005019458A1 (de) * 2005-04-25 2006-10-26 Grünenthal GmbH Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
EP1902087A1 (de) * 2005-07-01 2008-03-26 Cinvention Ag Verfahren zur herstellung von porösen retikulierten verbundwerkstoffen
AU2006265196A1 (en) * 2005-07-01 2007-01-11 Cinvention Ag Medical devices comprising a reticulated composite material
DE202006006920U1 (de) * 2006-04-25 2007-08-30 Biomed Est. Dentalimplantat
US20070073385A1 (en) * 2005-09-20 2007-03-29 Cook Incorporated Eluting, implantable medical device
WO2007051166A2 (en) * 2005-10-28 2007-05-03 Biomedflex, Llc Resilient thin film treatment of superelastic and shape memory metal components
EP1976627A2 (de) * 2005-12-09 2008-10-08 Drexel University Mesoporöse kohlenstoffe
US20070154514A1 (en) * 2005-12-30 2007-07-05 Demakas John J Therapeutic Structures
US7862897B2 (en) * 2006-01-27 2011-01-04 Carbon Ceramics Company, Llc Biphasic nanoporous vitreous carbon material and method of making the same
US20070191931A1 (en) * 2006-02-16 2007-08-16 Jan Weber Bioerodible endoprostheses and methods of making the same
US9526814B2 (en) * 2006-02-16 2016-12-27 Boston Scientific Scimed, Inc. Medical balloons and methods of making the same
WO2007106438A2 (en) * 2006-03-10 2007-09-20 Versilant Nanotechnologies Llc Methods of manufacturing highly polished gemstones
US20070270970A1 (en) * 2006-03-14 2007-11-22 Sdgi Holdings, Inc. Spinal implants with improved wear resistance
US20070270971A1 (en) * 2006-03-14 2007-11-22 Sdgi Holdings, Inc. Intervertebral prosthetic disc with improved wear resistance
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US20070233246A1 (en) * 2006-03-31 2007-10-04 Sdgi Holdings, Inc. Spinal implants with improved mechanical response
US7709045B2 (en) * 2006-04-28 2010-05-04 Boston Scientific Scimed, Inc. Medical devices coated with porous carbon and methods of manufacturing the same
CN100447319C (zh) * 2006-06-08 2008-12-31 利芳建医药科技咨询(上海)有限公司 一种防治乳腺增生的药用蛋白质纤维及其制备和应用
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
CA2655793A1 (en) 2006-06-29 2008-01-03 Boston Scientific Limited Medical devices with selective coating
US20080021462A1 (en) * 2006-07-24 2008-01-24 Warsaw Orthopedic Inc. Spinal stabilization implants
US20080021557A1 (en) * 2006-07-24 2008-01-24 Warsaw Orthopedic, Inc. Spinal motion-preserving implants
JP2010503469A (ja) 2006-09-14 2010-02-04 ボストン サイエンティフィック リミテッド 薬物溶出性皮膜を有する医療デバイス
US20080069858A1 (en) * 2006-09-20 2008-03-20 Boston Scientific Scimed, Inc. Medical devices having biodegradable polymeric regions with overlying hard, thin layers
CA2668408A1 (en) * 2006-11-03 2008-05-15 Boston Scientific Limited Ion bombardment of medical devices
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US8052903B2 (en) * 2006-12-25 2011-11-08 Christopher Whitmarsh Vitreous carbon material and process for making the same
CN101646402A (zh) * 2007-01-19 2010-02-10 金文申有限公司 用粉末模塑法制成的多孔、不可降解植入物
DE102007007865A1 (de) * 2007-02-14 2008-08-21 Jennissen, Herbert, Prof. Dr. Verfahren zur Herstellung von lagerfähigen Implantaten mit einer ultrahydrophilen Oberfläche
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US20100167401A1 (en) * 2007-03-19 2010-07-01 Vasif Hasirci Stacked, patterned biomaterials and/or tissue engineering scaffolds
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US7942926B2 (en) * 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
WO2009012353A2 (en) 2007-07-19 2009-01-22 Boston Scientific Limited Endoprosthesis having a non-fouling surface
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
WO2009018340A2 (en) 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
JP2010535541A (ja) 2007-08-03 2010-11-25 ボストン サイエンティフィック リミテッド 広い表面積を有する医療器具用のコーティング
US7883736B2 (en) * 2007-09-06 2011-02-08 Boston Scientific Scimed, Inc. Endoprostheses having porous claddings prepared using metal hydrides
US8845751B2 (en) * 2007-09-21 2014-09-30 Waldemar Link Gmbh & Co. Kg Endoprosthesis component
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7938855B2 (en) * 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US20090118818A1 (en) * 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Endoprosthesis with coating
EP2271380B1 (de) 2008-04-22 2013-03-20 Boston Scientific Scimed, Inc. Medizinprodukte mit einer beschichtung aus anorganischem material
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
EP2303350A2 (de) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprothesen-beschichtung
CA2653866A1 (en) * 2008-07-03 2010-01-03 Induce Biologics Inc. Use of immobilized antagonists for enhancing growth factor containing bioimplant effectiveness
DE102008040786A1 (de) * 2008-07-28 2010-02-04 Biotronik Vi Patent Ag Biokorrodierbares Implantat mit einer Beschichtung enthaltend eine wirkstofftragende Polymermatrix
JP5878369B2 (ja) 2008-08-07 2016-03-08 エクソジェネシス コーポレーション 骨インプラントのための医療機器およびその機器の製造方法
US20100070013A1 (en) * 2008-09-18 2010-03-18 Medtronic Vascular, Inc. Medical Device With Microsphere Drug Delivery System
WO2010038059A2 (en) * 2008-10-02 2010-04-08 Fujifilm Manufacturing Europe Bv Antimicrobial coating
US20100131051A1 (en) * 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Systems and Methods for Treatment of Aneurysms Using Zinc Chelator(s)
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
KR101087088B1 (ko) 2008-12-29 2011-11-25 한국과학기술연구원 나노 구조 패턴을 갖는 약물 방출용 스텐트의 제조방법 및 이로부터 제조된 약물 방출용 스텐트
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US20100233227A1 (en) * 2009-03-10 2010-09-16 Boston Scientific Scimed, Inc. Medical devices having carbon drug releasing layers
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
DE102009024616A1 (de) * 2009-06-08 2010-12-23 Telos Gmbh Sterilisierbare Implantatbeschichtung und Verfahren zu deren Herstellung
FR2949687B1 (fr) * 2009-09-04 2011-09-23 Sofradim Production Tissu avec picots revetus d'un materiau hydrosoluble
FR2949688B1 (fr) * 2009-09-04 2012-08-24 Sofradim Production Tissu avec picots revetu d'une couche microporeuse bioresorbable
EP2512383B1 (de) 2009-12-14 2016-04-13 Ascension Orthopedics, Inc. Oberflächenersatzimplantat für humeruskopf
US8882740B2 (en) * 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone
JP5806289B2 (ja) 2010-04-06 2015-11-10 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 内部人工器官
US20130180913A1 (en) * 2010-07-16 2013-07-18 Cnanoz Inc Water filtration system using hybrid nano carbon, silver, iron and aluminium oxide
US9339387B2 (en) * 2010-10-13 2016-05-17 Cibor, Inc. Synthetic bone grafts constructed from carbon foam materials
CA2817584C (en) 2010-11-15 2018-01-02 Zimmer Orthobiologics, Inc. Bone void fillers
CN102485184A (zh) * 2010-12-03 2012-06-06 令狐恩强 一种纳米银抗菌胆管支架及其制备方法
US20120158139A1 (en) * 2010-12-17 2012-06-21 Bio2 Technologies, Inc. Method and Apparatus for a Porous Orthopedic Implant
WO2012094708A1 (en) * 2011-01-12 2012-07-19 The University Of Queensland Bone graft biomaterial
KR101240075B1 (ko) * 2011-05-09 2013-03-07 동국대학교 산학협력단 의료용 임플란트 및 그의 제조방법
FR2976577B1 (fr) * 2011-06-17 2014-03-28 Saint Gobain Procede de fabrication d'un vitrage comprenant une couche poreuse
KR101277658B1 (ko) * 2011-07-11 2013-06-21 조선대학교산학협력단 다중 약물전달계를 갖는 생체의료용 세라믹 재료의 제조 방법
RU2477627C1 (ru) * 2011-07-18 2013-03-20 Общество с ограниченной ответственностью "ИЛЬКОМ" Полимерный композиционный материал
CN104039312A (zh) * 2011-08-16 2014-09-10 实验室护肤股份有限公司 细干颗粒腺苷组合物和包括其的局部制剂
US9484123B2 (en) 2011-09-16 2016-11-01 Prc-Desoto International, Inc. Conductive sealant compositions
KR101393592B1 (ko) * 2012-03-06 2014-05-14 한양대학교 산학협력단 내구성이 우수한 인공뼈 및 그 제조방법
RU2505602C1 (ru) * 2012-06-04 2014-01-27 Федеральное государственное бюджетное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения и социального развития РФ (ФГБУ "РКНПК" Минздравсоцразвития России) Способ получения резидентных стволовых клеток сердца млекопитающего из образцов миокарда
EP2858554A4 (de) * 2012-06-11 2016-02-24 Univ California Verfahren und system für in-vivo-wasserstoffperoxidnachweis mit ultraschall
DE102013201885A1 (de) 2013-02-05 2014-08-07 Urs Brodbeck Keramikkörper, insbesondere zur Verwendung in einem Knochenimplantat, insbesondere als Dentalimplantat
EP2967799B1 (de) * 2013-03-14 2020-09-02 Osteoceramics, Inc. Systeme und verfahren zur verwendung von durch infektionen aktivierten chemisch gebundenen antibiotika
WO2014151580A1 (en) * 2013-03-15 2014-09-25 Clarion University of Pennsylvania Surface modified dental implant
KR101644686B1 (ko) 2014-04-17 2016-08-02 서울대학교산학협력단 가교된 폴리포스포릴콜린으로 코팅된 체내 삽입용 보형물
US11766506B2 (en) * 2016-03-04 2023-09-26 Mirus Llc Stent device for spinal fusion
RU2626896C1 (ru) * 2016-11-11 2017-08-02 Общество с ограниченной ответственностью "ЭЛЕСТИМ-КАРДИО" Эндокардиальная электродная система для стимуляции левых отделов сердца
KR102173645B1 (ko) * 2018-12-28 2020-11-05 (주)에이치피케이 약물 방출 탄소 섬유 스텐트 및 그 제조방법
CN109603769A (zh) * 2019-01-08 2019-04-12 咸阳师范学院 一种苯酚吸附材料的制备方法及应用
CN117064579B (zh) * 2023-10-17 2024-01-12 山东百多安医疗器械股份有限公司 一种氮化硅陶瓷种植体及制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999064085A1 (de) * 1998-06-09 1999-12-16 Franz Herbst Verfahren zur herstellung von biokompatiblen oberflächen
WO2002080996A1 (de) * 2001-04-03 2002-10-17 Franz Herbst Medizinisches implantat und verfahren zu seiner herstellung

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3623164A (en) * 1969-10-06 1971-11-30 Gulf Oil Corp Prosthetic device
US3685059A (en) * 1970-07-28 1972-08-22 Gulf General Atomic Inc Prosthetic blood circulation device having a pyrolytic carbon coated blood contacting surface
US4209480A (en) * 1972-10-24 1980-06-24 Homsy Charles A Implantable material and method of preparing same
US4549977A (en) * 1976-09-29 1985-10-29 Colgate-Palmolive Company Bottled particulate detergent
JPS5441913A (en) * 1977-09-09 1979-04-03 Kanebo Ltd Carbonncarbon composite material and method of making same
US4318948A (en) * 1979-07-25 1982-03-09 Fordath Limited Article comprising carbon fibres and method of producing the article
JPS62119161A (ja) * 1985-11-14 1987-05-30 呉羽化学工業株式会社 可撓性炭素材料およびその製造方法
JP2852305B2 (ja) * 1986-11-14 1999-02-03 杉郎 大谷 人工補▲てん▼補綴材料
US5163958A (en) 1989-02-02 1992-11-17 Cordis Corporation Carbon coated tubular endoprosthesis
US4986943A (en) * 1989-02-28 1991-01-22 The Aerospace Corporation Method for oxidation stabilization of pitch-based matrices for carbon-carbon composites
US5171492A (en) * 1989-04-26 1992-12-15 Mitsubishi Pencil Co., Ltd. Process for producing carbonaceous implant material
US5209979A (en) * 1990-01-17 1993-05-11 Ethyl Corporation Silicon carbide coated article with ceramic topcoat
JPH04220261A (ja) * 1990-12-19 1992-08-11 Sumitomo Electric Ind Ltd ダイヤモンド被覆生体用部材
US5451444A (en) * 1993-01-29 1995-09-19 Deliso; Evelyn M. Carbon-coated inorganic substrates
US5382642A (en) * 1993-07-28 1995-01-17 Arco Chemical Technology, L.P. Copolymers of allyl alcohol propoxylates and vinyl aromatic monomers
US5516884A (en) * 1994-03-09 1996-05-14 The Penn State Research Foundation Preparation of polycarbynes and diamond-like carbon materials made therefrom
US5605714A (en) * 1994-03-29 1997-02-25 Southwest Research Institute Treatments to reduce thrombogeneticity in heart valves made from titanium and its alloys
ATE202971T1 (de) * 1994-09-23 2001-07-15 Impra Inc Kohlenstoffhaltiges gefässtransplantat und herstellungsverfahren
RU2095464C1 (ru) 1996-01-12 1997-11-10 Акционерное общество закрытого типа "Тетра" Биокарбон, способ его получения и устройство для его осуществления
US5891507A (en) 1997-07-28 1999-04-06 Iowa-India Investments Company Limited Process for coating a surface of a metallic stent
US6156697A (en) * 1997-11-04 2000-12-05 Corning Incorporated Method of producing high surface area carbon structures
US6203505B1 (en) 1998-06-05 2001-03-20 Advanced Cardiovascular Systems, Inc. Guidewires having a vapor deposited primer coat
CN1138701C (zh) * 1998-07-20 2004-02-18 康宁股份有限公司 采用孔形成物制备中孔性碳的方法
US6497729B1 (en) * 1998-11-20 2002-12-24 The University Of Connecticut Implant coating for control of tissue/implant interactions
JP2000237299A (ja) * 1999-02-18 2000-09-05 Yasuhiro Fukui 生体適合性材及びその形成方法
US6372283B1 (en) * 1999-04-02 2002-04-16 Medtronic, Inc. Plasma process for surface modification of pyrolitic carbon
DE19951477A1 (de) 1999-10-26 2001-05-03 Biotronik Mess & Therapieg Stent
ATE457751T1 (de) 2000-07-28 2010-03-15 Blue Medical Devices B V Intravaskulärer stent mit expandierbarer beschichtung
DE10051910A1 (de) * 2000-10-19 2002-05-02 Membrana Mundi Gmbh Flexible, poröse Membranen und Adsorbentien, und Verfahren zu deren Herstellung
US20040018228A1 (en) * 2000-11-06 2004-01-29 Afmedica, Inc. Compositions and methods for reducing scar tissue formation
US6544582B1 (en) * 2001-01-05 2003-04-08 Advanced Cardiovascular Systems, Inc. Method and apparatus for coating an implantable device
WO2003049795A2 (en) * 2001-09-28 2003-06-19 Boston Scientific Limited Medical devices comprising nanocomposites
US20030093147A1 (en) * 2001-11-13 2003-05-15 Ogle Matthew F. Medical devices that stimulate growth factor production
US20030104028A1 (en) * 2001-11-29 2003-06-05 Hossainy Syed F.A. Rate limiting barriers for implantable devices and methods for fabrication thereof
US20040010108A1 (en) * 2002-03-25 2004-01-15 Bianconi Patricia A. High molecular weight polymers
CZ295032B6 (cs) 2002-05-23 2005-05-18 Škoda Auto a. s. Ochranná lišta prahu dveří automobilu se svíticím efektem
US6859986B2 (en) * 2003-02-20 2005-03-01 Cordis Corporation Method system for loading a self-expanding stent
WO2004101017A2 (de) 2003-05-16 2004-11-25 Blue Membranes Gmbh Biokompatibel beschichtete medizinische implantate
DE10324415A1 (de) 2003-05-28 2004-12-16 Blue Membranes Gmbh Verfahren zur Beschichtung von Substraten mit kohlenstoffbasiertem Material
DE10322182A1 (de) 2003-05-16 2004-12-02 Blue Membranes Gmbh Verfahren zur Herstellung von porösem, kohlenstoffbasiertem Material
AU2004238517A1 (en) 2003-05-16 2004-11-25 Cinvention Ag Method for coating substrates with a carbon-based material
DE10333098A1 (de) 2003-07-21 2005-02-10 Blue Membranes Gmbh Biokompatibel beschichtete medizinische Implantate
DE10335131A1 (de) 2003-07-31 2005-02-24 Blue Membranes Gmbh Verfahren und Herstellung von porösen kohlenstoffbasierten Formkörpern

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999064085A1 (de) * 1998-06-09 1999-12-16 Franz Herbst Verfahren zur herstellung von biokompatiblen oberflächen
WO2002080996A1 (de) * 2001-04-03 2002-10-17 Franz Herbst Medizinisches implantat und verfahren zu seiner herstellung

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