WO2004105153A3 - Micro/nano fluidic 3-dimensional electrode system - Google Patents

Micro/nano fluidic 3-dimensional electrode system Download PDF

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Publication number
WO2004105153A3
WO2004105153A3 PCT/KR2004/001194 KR2004001194W WO2004105153A3 WO 2004105153 A3 WO2004105153 A3 WO 2004105153A3 KR 2004001194 W KR2004001194 W KR 2004001194W WO 2004105153 A3 WO2004105153 A3 WO 2004105153A3
Authority
WO
WIPO (PCT)
Prior art keywords
micro
dielectric substrate
nano
electrode system
dimensional electrode
Prior art date
Application number
PCT/KR2004/001194
Other languages
French (fr)
Other versions
WO2004105153A2 (en
Inventor
Je-Kyun Park
Yu-Heon Yi
Seung-Joo Kang
Original Assignee
All Medicus Co Ltd
Je-Kyun Park
Korea Advanced Inst Sci & Tech
Yu-Heon Yi
Seung-Joo Kang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by All Medicus Co Ltd, Je-Kyun Park, Korea Advanced Inst Sci & Tech, Yu-Heon Yi, Seung-Joo Kang filed Critical All Medicus Co Ltd
Publication of WO2004105153A2 publication Critical patent/WO2004105153A2/en
Publication of WO2004105153A3 publication Critical patent/WO2004105153A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0896—Nanoscaled

Abstract

The present invention discloses a three-dimensional electrode system having an integrated micro/nano fluidic channel. The three-dimensional electrode system comprises a first dielectric substrate, a second dielectric substrate facing the first dielectric substrate with a predetermined gap in-between, a plurality of oxidation electrodes formed on the first dielectric substrate, and a plurality of reduction electrodes formed on the second dielectric substrate. A micro/nano fluidic channel is formed between the first and second dielectric substrates. The oxidation and reduction electrodes are formed in predetermined intervals along the micro/nano fluidic channel and substantially perpendicular to the micro/nano fluidic channel. The electrodes are electrically interconnected. A bio-fluidic flows through the micro/nano fluid channel in zigzags, not straight, such that mixing of the fluid can be facilitated, and oxidation and reduction reactions of electroactive species contained in the fluid can be electrochemically analyzed with a high degree of efficiency.
PCT/KR2004/001194 2003-05-23 2004-05-21 Micro/nano fluidic 3-dimensional electrode system WO2004105153A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020030033064A KR100563834B1 (en) 2003-05-23 2003-05-23 Micor/nano fluidic 3 dimensional electrode system
KR10-2003-0033064 2003-05-23

Publications (2)

Publication Number Publication Date
WO2004105153A2 WO2004105153A2 (en) 2004-12-02
WO2004105153A3 true WO2004105153A3 (en) 2005-02-03

Family

ID=33476008

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2004/001194 WO2004105153A2 (en) 2003-05-23 2004-05-21 Micro/nano fluidic 3-dimensional electrode system

Country Status (2)

Country Link
KR (1) KR100563834B1 (en)
WO (1) WO2004105153A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100535649C (en) * 2006-03-30 2009-09-02 中国科学院电子学研究所 Microelectrode biosensing chip of 3D nanogap mesh array

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG131130A1 (en) * 2004-07-06 2007-04-26 Agency Science Tech & Res Biochip for sorting and lysing biological samples
KR100738085B1 (en) 2005-12-21 2007-07-12 삼성전자주식회사 A microfluidic device for electrochemically regulating the pH of a fluid therein and method for regulating the pH of a fluid in a microfuidic device using the same
CN100399016C (en) * 2006-04-22 2008-07-02 福州大学 Microfluidic chip electrode for electrochemical detection and method for manufacturing microfluidic chip
KR100864536B1 (en) * 2006-08-01 2008-10-21 고려대학교 산학협력단 Method for forming a fine electrode using polydimethylsiloxane and Fine electrode formed by the same
JP2008057384A (en) * 2006-08-30 2008-03-13 Yasumasa Nagao Fluid forcible circulation device and fluid forcible circulation method
KR100844143B1 (en) * 2007-05-02 2008-07-04 재단법인서울대학교산학협력재단 Method for fabricating for three dimensional structured micro-electrode array
KR100931303B1 (en) 2008-12-12 2009-12-11 한국과학기술원 Microfluidic chip for microparticle focusing and sorting in slanted substrate
KR101135084B1 (en) 2008-12-23 2012-04-16 한국전자통신연구원 Microfluidic device and microfluidic analysis equipment
KR101097357B1 (en) 2009-07-09 2011-12-23 한국과학기술원 Multi function microfluidic flow control apparatus and multi function microfluidic flow control method
KR101363157B1 (en) 2010-10-07 2014-02-26 주식회사 세라젬메디시스 three-dimensional biosensor
US20150219592A1 (en) * 2012-07-20 2015-08-06 Northeastern University Microfluidic-nanofluidic devices for detection and measurement of redox active substances
CN105536894B (en) * 2015-12-02 2017-06-20 哈尔滨工业大学 A kind of high flux microring array chip based on AC Electric Heater and application
CN107442186B (en) * 2016-05-31 2020-06-09 深圳汇芯生物医疗科技有限公司 Microfluidic chip, analysis device based on microfluidic chip and analysis method
KR102088937B1 (en) * 2018-04-19 2020-03-13 연세대학교 산학협력단 Electrochemical aptasensor having microfluidic circuit
EP3877502A4 (en) * 2018-11-08 2022-08-03 Georgia Tech Research Corporation Parallel electrodes sensor
WO2020226624A1 (en) * 2019-05-07 2020-11-12 Hewlett-Packard Development Company, L.P. Fluid identification via electrochemical labels

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5670031A (en) * 1993-06-03 1997-09-23 Fraunhofer-Gesellschaft Zur Angewandten Forschung E.V. Electrochemical sensor
US6110354A (en) * 1996-11-01 2000-08-29 University Of Washington Microband electrode arrays
US20010021534A1 (en) * 1995-03-10 2001-09-13 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US20010053535A1 (en) * 2000-04-17 2001-12-20 Purdue Research Foundation Biosensor and related method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5670031A (en) * 1993-06-03 1997-09-23 Fraunhofer-Gesellschaft Zur Angewandten Forschung E.V. Electrochemical sensor
US20010021534A1 (en) * 1995-03-10 2001-09-13 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US6110354A (en) * 1996-11-01 2000-08-29 University Of Washington Microband electrode arrays
US20010053535A1 (en) * 2000-04-17 2001-12-20 Purdue Research Foundation Biosensor and related method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GERWEN P.V. ET AL.: "Sensors and actuators B", vol. 49, 1998, BELGIUM, pages 73 - 80 *
KURITA R. ET AL.: "Sensors and actuators B", vol. 71, 2000, JAPAN, pages 82 - 89 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100535649C (en) * 2006-03-30 2009-09-02 中国科学院电子学研究所 Microelectrode biosensing chip of 3D nanogap mesh array

Also Published As

Publication number Publication date
KR20040100646A (en) 2004-12-02
WO2004105153A2 (en) 2004-12-02
KR100563834B1 (en) 2006-03-28

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