WO2004091438A3 - Improved ophthalmic and contact lens solutions containing peptides as representative enhancers - Google Patents

Improved ophthalmic and contact lens solutions containing peptides as representative enhancers Download PDF

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Publication number
WO2004091438A3
WO2004091438A3 PCT/US2004/011575 US2004011575W WO2004091438A3 WO 2004091438 A3 WO2004091438 A3 WO 2004091438A3 US 2004011575 W US2004011575 W US 2004011575W WO 2004091438 A3 WO2004091438 A3 WO 2004091438A3
Authority
WO
WIPO (PCT)
Prior art keywords
contact lens
solutions containing
containing peptides
lens solutions
improved ophthalmic
Prior art date
Application number
PCT/US2004/011575
Other languages
French (fr)
Other versions
WO2004091438A2 (en
WO2004091438B1 (en
Inventor
Francis X Smith
Kathryn S Crawford
Original Assignee
Fxs Ventures Llc
Francis X Smith
Kathryn S Crawford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fxs Ventures Llc, Francis X Smith, Kathryn S Crawford filed Critical Fxs Ventures Llc
Priority to US10/593,352 priority Critical patent/US7939501B2/en
Publication of WO2004091438A2 publication Critical patent/WO2004091438A2/en
Publication of WO2004091438A3 publication Critical patent/WO2004091438A3/en
Publication of WO2004091438B1 publication Critical patent/WO2004091438B1/en
Priority to US13/037,802 priority patent/US20110212885A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/141Biguanides, e.g. chlorhexidine
    • A61L12/142Polymeric biguanides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005Other compounding ingredients characterised by their effect
    • C11D3/0078Compositions for cleaning contact lenses, spectacles or lenses
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions

Abstract

A contact lens solution comprising 0.001 to 10 weight percent or a preservative enhancer chosen from the group consisting of: D4E 1, D2A2 1, and P- 113; and at least 0.0001 weight percent of a preservative, and where the concentration of chloride in said solution is less than 0.2 percent by weight.
PCT/US2004/011575 2003-04-15 2004-04-15 Improved ophthalmic and contact lens solutions containing peptides as representative enhancers WO2004091438A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10/593,352 US7939501B2 (en) 2003-04-15 2004-04-15 Ophthalmic and contact lens solutions containing peptides as preservative
US13/037,802 US20110212885A1 (en) 2003-04-15 2011-03-01 Ophthalmic and contact lens solutions containing peptides as preservative

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46294003P 2003-04-15 2003-04-15
US60/462,940 2003-04-15

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/037,802 Continuation US20110212885A1 (en) 2003-04-15 2011-03-01 Ophthalmic and contact lens solutions containing peptides as preservative

Publications (3)

Publication Number Publication Date
WO2004091438A2 WO2004091438A2 (en) 2004-10-28
WO2004091438A3 true WO2004091438A3 (en) 2005-03-24
WO2004091438B1 WO2004091438B1 (en) 2005-05-06

Family

ID=33300015

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/011575 WO2004091438A2 (en) 2003-04-15 2004-04-15 Improved ophthalmic and contact lens solutions containing peptides as representative enhancers

Country Status (2)

Country Link
US (2) US7939501B2 (en)
WO (1) WO2004091438A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8557868B2 (en) 2000-11-04 2013-10-15 Fxs Ventures, Llc Ophthalmic and contact lens solutions using low molecular weight amines
US9492582B2 (en) * 2000-11-08 2016-11-15 Fxs Ventures, Llc Ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers
WO2004091438A2 (en) * 2003-04-15 2004-10-28 Fxs Ventures, Llc Improved ophthalmic and contact lens solutions containing peptides as representative enhancers
PL2038310T3 (en) 2006-07-12 2010-11-30 Novartis Ag Actinically crosslinkable copolymers for manufacturing contact lenses
AR064286A1 (en) 2006-12-13 2009-03-25 Quiceno Gomez Alexandra Lorena PRODUCTION OF OPHTHALMIC DEVICES BASED ON POLYMERIZATION BY PHOTOINDUCIDED SCALE GROWTH
CA2692831C (en) 2007-08-31 2016-05-17 Novartis Ag Contact lens packaging solutions
TWI551305B (en) 2007-08-31 2016-10-01 諾華公司 Use of a relatively-viscous packaging solution
US20130310326A1 (en) 2012-05-18 2013-11-21 Rapid Pathogen Screening, Inc. Histatin for Corneal Wound Healing and Ocular Surface Disease
PL3383631T3 (en) 2015-12-03 2020-03-31 Novartis Ag Contact lens packaging solutions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162393A (en) * 1998-08-06 2000-12-19 Ndt, Inc. Contact lens and ophthalmic solutions

Family Cites Families (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2976576A (en) 1956-04-24 1961-03-28 Wichterle Otto Process for producing shaped articles from three-dimensional hydrophilic high polymers
US3429576A (en) 1965-08-28 1969-02-25 Yoshiaki Ikeda Golf club having level indicating means and weight means
US3503393A (en) 1966-05-19 1970-03-31 Blease Anaesthetic Equip Ltd Patient controlled respiratory apparatus
DE1667942B2 (en) 1967-03-15 1977-05-12 Ceskoslovenska Akademie Ved, Prag METHOD AND DEVICE FOR STERILE STORAGE OF OBJECTS FROM SWELLED HYDOGELS, IN PARTICULAR OF CONTACT LENSES
US3689673A (en) 1970-11-10 1972-09-05 Barnes Hind Pharm Inc The process of soaking and sterilizing hydrophilic soft contact lenses with chlorhexidene
US3755561A (en) 1971-03-22 1973-08-28 Burton Parsons & Co Inc Bactericidal contact lens solution
FR2199470B1 (en) 1971-06-21 1977-12-30 Wave Energy Systems
US3873696A (en) 1972-01-31 1975-03-25 Allergan Pharma Cleaning and sterilizing soft contact lens
NO135634C (en) 1972-03-16 1977-05-04 Farmaceutisk Ind As
US4022834A (en) 1972-03-16 1977-05-10 A/S Farmaceutisk Industri Antibacterially active hexamethylene-bis-biguanides
US3888782A (en) 1972-05-08 1975-06-10 Allergan Pharma Soft contact lens preserving solution
US3876768A (en) 1972-11-06 1975-04-08 Hydrophilics Int Inc Sterilization of soft, hydrophilic acrylate and methacrylate copolymer materials
US3911107A (en) 1972-12-18 1975-10-07 Flow Pharma Inc Iodine composition and dissipating solution
US3910296A (en) 1973-04-20 1975-10-07 Allergan Pharma Method of removing proteinaceous deposits from contact lenses
US3943251A (en) 1973-06-27 1976-03-09 Medow Norman B Ophthamological use of hydrastis compounds
US4029817A (en) 1973-09-24 1977-06-14 Allergan Pharmaceuticals Soft contact lens preserving solutions
GB1562899A (en) 1975-06-17 1980-03-19 Wellcome Found Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof
US4046706A (en) 1976-04-06 1977-09-06 Flow Pharmaceuticals, Inc. Contact lens cleaning composition
IT1063325B (en) 1976-05-19 1985-02-11 Brevitex Ets Exploit DEVICE FOR SPREADING THE CROSSBODY FRAMES
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4209817A (en) 1978-03-15 1980-06-24 Square D Company Circuit breaker having an electronic fault sensing and trip initiating unit
US4394381A (en) 1979-04-13 1983-07-19 George F. And Irene Sherrill 1978 Trust No. 1 Method for the relief of pain
US4361549A (en) 1979-04-26 1982-11-30 Ortho Pharmaceutical Corporation Complement-fixing monoclonal antibody to human T cells, and methods of preparing same
US4894464A (en) * 1980-01-21 1990-01-16 Pfizer Inc. Branched amides of L-aspartyl-D-amino acid dipeptides
JPS599600B2 (en) 1980-11-14 1984-03-03 花王株式会社 Shampoo - Composition
US4361548A (en) 1980-11-28 1982-11-30 Bausch & Lomb Incorporated Contact lens disinfecting and preserving solution (polymeric)
US4361458A (en) 1981-02-13 1982-11-30 The Wurlitzer Company Piano soundboard and method of making same
US4354952A (en) 1981-03-12 1982-10-19 Bausch & Lomb Incorporated Contact lens disinfecting and preserving solution comprising chlorhexidine and salts thereof
JPS5810517A (en) 1981-07-13 1983-01-21 Santen Pharmaceut Co Ltd Ophthalmic solution containing non-steroid antiphlogistic agent as main component
US4525346A (en) 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
US4820352A (en) 1983-01-10 1989-04-11 Bausch & Lomb Incorporated Cleaning and conditioning solutions for contact lenses and methods of use
JPS6038323A (en) 1983-08-10 1985-02-27 Sankyo Co Ltd Ophthalmic anti-inflammatory agent
US4836986A (en) 1984-09-28 1989-06-06 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
US4748189A (en) 1985-04-19 1988-05-31 Ciba-Geigy Corporation Ophthalmic solutions and methods for improving the comfort and safety of contact lenses
USRE32672E (en) 1985-09-09 1988-05-24 Allergan, Inc. Method for simultaneously cleaning and disinfecting contact lenses using a mixture of peroxide and proteolytic enzyme
JPH0696521B2 (en) 1986-01-31 1994-11-30 千寿製薬株式会社 Ocular hypotensive agent for topical ocular administration
JPH0672866B2 (en) * 1986-03-19 1994-09-14 本田技研工業株式会社 Oxygen concentration detector
US4874850A (en) 1986-08-07 1989-10-17 Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Pharmaceutical preparations
US4863900A (en) 1987-01-15 1989-09-05 The Research Foundation Of State University Of New York Method for reducing viral transmission with poly-L-histidine
US4783488A (en) 1987-01-31 1988-11-08 Bausch & Lomb Incorporated Contact lens wetting solution
US5246708A (en) 1987-10-28 1993-09-21 Pro-Neuron, Inc. Methods for promoting wound healing with deoxyribonucleosides
US5624958A (en) 1987-12-31 1997-04-29 Isaacs; Charles E. Disinfecting contact lenses
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
JPH01211595A (en) 1988-02-18 1989-08-24 Kikkoman Corp Novel n-acetyl-beta-d-glucosamine derivative, production thereof and utilization thereof to reagent for measuring n-acetyl-beta-d-glucosamidase activity
US5607698A (en) 1988-08-04 1997-03-04 Ciba-Geigy Corporation Method of preserving ophthalmic solution and compositions therefor
US5089261A (en) 1989-01-23 1992-02-18 Cetus Corporation Preparation of a polymer/interleukin-2 conjugate
US4891423A (en) 1989-03-20 1990-01-02 Stockel Richard F Polymeric biguanides
US5182258A (en) 1989-03-20 1993-01-26 Orbon Corporation Systemic delivery of polypeptides through the eye
US5175161A (en) 1989-04-06 1992-12-29 Sankyo Company, Limited Occular hypotensive agents
JP2893537B2 (en) 1989-07-20 1999-05-24 東海電化工業株式会社 Histidine-hydrogen peroxide adduct and method for producing the same
US4988710A (en) 1989-08-25 1991-01-29 Washington University Aryl-cycloalkyl-alkanolamines for treatment of cholinergic neurotoxins
US5078908A (en) 1989-10-02 1992-01-07 Allergan, Inc. Methods for generating chlorine dioxide and compositions for disinfecting
US4997626A (en) 1990-01-05 1991-03-05 Allergan, Inc. Methods to disinfect contact lenses
US5279673A (en) 1990-01-05 1994-01-18 Allergan, Inc. Methods to disinfect contact lenses
US5300296A (en) 1989-11-06 1994-04-05 Frank J. Holly Antimicrobial agent for opthalmic formulations
GB9002422D0 (en) 1990-02-03 1990-04-04 Boots Co Plc Anti-microbial compositions
US5174872A (en) 1990-06-08 1992-12-29 Technicon Instruments Corporation Metal-free buffer for ion selective electrode-based assays
EP0563250A1 (en) 1990-12-19 1993-10-06 Allergan, Inc. Compositions and methods for contact lens disinfecting
US5439572A (en) 1991-12-02 1995-08-08 Isoclear, Inc. Lens protective encasement packet
AU6363694A (en) 1993-03-18 1994-10-11 Polymer Technology Corporation Alcohol-containing abrasive composition for cleaning contact lenses
DE4345199C2 (en) 1993-05-22 1995-10-12 Asta Medica Ag Use of dihydrolipoic acid to suppress intolerance reactions in the border area of implants with living body tissue
ES2122288T3 (en) 1993-05-26 1998-12-16 Fresenius Ag ANTI-INFECTIOUS.
US5661130A (en) 1993-06-24 1997-08-26 The Uab Research Foundation Absorption enhancers for drug administration
US5449658A (en) 1993-12-07 1995-09-12 Zeneca, Inc. Biocidal compositions comprising polyhexamethylene biguanide and EDTA, and methods for treating commercial and recreational water
US5591773A (en) 1994-03-14 1997-01-07 The Trustees Of Columbia University In The City Of New York Inhibition of cataract formation, diseases resulting from oxidative stress, and HIV replication by caffeic acid esters
US5361287A (en) 1994-03-29 1994-11-01 B&W Fuel Company Nuclear fuel assembly lower end fitting
NZ283658A (en) 1994-04-04 1999-09-29 William R Freeman Compositions and treatment of increased intraocular pressure with phosphonyl-alkyloxy-pyrimidines/purines (nucleosides)
US5674450A (en) 1994-04-28 1997-10-07 Johnson & Johnson Medical, Inc. Vapor sterilization using a non-aqueous source of hydrogen peroxide
US5547990A (en) 1994-05-20 1996-08-20 Lonza, Inc. Disinfectants and sanitizers with reduced eye irritation potential
US5494937A (en) 1994-07-22 1996-02-27 Alcon Laboratories, Inc. Saline solution for treating contact lenses
AU3070395A (en) 1994-07-22 1996-02-22 Alcon Laboratories, Inc. Use of low molecular weight amino acids in ophthalmic compositions
ES2129850T3 (en) * 1994-09-20 1999-06-16 Wakunaga Seiyaku Kk PRODUCTION PROCEDURE OF A DERIVATIVE OF N-BIPHENYL METHYLTIADIAZOLINE OR A SALT OF IT AND ITS INTERMEDIATE PRODUCTION OF PRODUCTION.
CA2160962C (en) 1994-10-20 2009-12-29 Junya Inoue Reagent for analyzing solid components in urine and method for analyzing solid components by employing the same
AU4865796A (en) * 1995-02-17 1996-09-04 Allergan, Inc. Ophthalmic compositions including peptides and peptide derivatives and methods for using same
US5739178A (en) 1995-05-15 1998-04-14 Allergan Polymer, article and method for inhibiting the growth of ocular pathogens in eye care products
US5718895A (en) 1995-11-16 1998-02-17 Alcon Laboratories, Inc. Enzymes with low isoelectric points for use in contact lens cleaning
US5780450A (en) 1995-11-21 1998-07-14 Alcon Laboratories, Inc. Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage
US5965736A (en) 1996-01-16 1999-10-12 Lumigen, Inc. Compositions and methods for generating red chemiluminescence
ES2210404T3 (en) 1996-01-22 2004-07-01 BAUSCH & LOMB INCORPORATED DOUBLE NEUTRALIZATION SYSTEM FOR TREATMENT WITH IODINE OF CONTACT LENSES.
EP0880356A4 (en) 1996-02-16 2002-03-27 Univ California Antimicrobial peptides and methods of use
US6358897B1 (en) 1996-06-07 2002-03-19 Alcon Laboratories, Inc. Alkyl trypsin compositions and methods of use in contact lens cleaning and disinfecting systems
JPH1059846A (en) 1996-06-10 1998-03-03 Kikkoman Corp Preventive or remedy for cararacta
US5719110A (en) 1996-08-14 1998-02-17 Allergan Contact lens care compositions with inositol phosphate components
JP3829380B2 (en) 1996-12-18 2006-10-04 住友化学株式会社 Pest repellent and pest repellent method
US5952320A (en) 1997-01-07 1999-09-14 Abbott Laboratories Macrocyclic inhibitors of matrix metalloproteinases and TNFα secretion
US5945446A (en) 1997-02-10 1999-08-31 Laubc Biochemicals, Corporation Process for preparing synthetic soil-extract materials and medicaments based thereon
US6022732A (en) 1997-04-09 2000-02-08 Allergan Hydrogen peroxide destroying compositions and methods of using same
RU2127100C1 (en) 1997-04-17 1999-03-10 Борзенок Сергей Анатольевич Ocular drops "pyrotonik"
US5811446A (en) 1997-04-18 1998-09-22 Cytos Pharmaceuticals Llc Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor
US5925320A (en) * 1997-06-04 1999-07-20 Jones; John P. Air purification system
JPH11137649A (en) 1997-11-10 1999-05-25 Tomey Technology Kk Method for cleaning and disinfecting contact lens
ID24946A (en) 1997-11-12 2000-08-31 Bausch & Lomb CONTACT LENS TREATMENT WITH WATER SOLUTION CONSIST OF ALKALI CARBONAT
WO1999024543A1 (en) 1997-11-12 1999-05-20 Bausch & Lomb Incorporated Disinfecting contact lenses with polyquaterniums and polymeric biguanides
US6056920A (en) 1997-12-12 2000-05-02 Vertex Pharmaceuticals Incorporated Process for identifying a solvent condition suitable for determining a biophysical property of a protein
JPH11249087A (en) 1997-12-18 1999-09-17 Tome:Kk Light agent for contact lens
US6156563A (en) * 1998-01-29 2000-12-05 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method for clarifying cane sugar juice
JP3883739B2 (en) 1998-05-22 2007-02-21 株式会社メニコン Contact lens bactericidal solution
JP2000016965A (en) 1998-06-29 2000-01-18 Mitsubishi Gas Chem Co Inc Production of hydroxyalkylacrylic ester or methacrylic acid ester modified with caprolactone
US6117869A (en) 1998-08-04 2000-09-12 Warner-Lambert Company Compounds for and methods of inhibiting matrix metalloproteinases
KR20010031258A (en) 1998-08-21 2001-04-16 요시다 쇼지 Compositions for contact lenses
US6309596B1 (en) 1998-12-15 2001-10-30 Bausch & Lomb Incorporated Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by a poloxamine
US7678836B2 (en) 1999-11-04 2010-03-16 Fxs Ventures, Llc Method for rendering a contact lens wettable
US6153563A (en) 1999-11-10 2000-11-28 Lithchem International Pouched ingredients for preparing greases
US8557868B2 (en) 2000-11-04 2013-10-15 Fxs Ventures, Llc Ophthalmic and contact lens solutions using low molecular weight amines
US6550862B2 (en) * 2001-06-14 2003-04-22 Cosco Management, Inc. Juvenile vehicle seat cup holder
US6624203B1 (en) 2001-11-08 2003-09-23 Francis X. Smith Nucleic acid bases used in ophthalmic solutions
US6617291B1 (en) 2001-11-08 2003-09-09 Francis X. Smith Ophthalmic and contact lens solutions
WO2004091438A2 (en) * 2003-04-15 2004-10-28 Fxs Ventures, Llc Improved ophthalmic and contact lens solutions containing peptides as representative enhancers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162393A (en) * 1998-08-06 2000-12-19 Ndt, Inc. Contact lens and ophthalmic solutions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BALLWEBER ET AL: "In vitro microbicidal activities of cecropin peptides D2A21 and D4E1 and Gell formulations containing 0.1 to 2% D2A21 against Chlamydia trachomatis", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 46, no. 1, January 2002 (2002-01-01), pages 34 - 41, XP002983178 *
DE LUCCA ET AL: "Fungicidal Properties, sterol binding, and proteolytic resistance of the synthetic peptide D4E1", CANADIAN JOURNAL OF MICROBIOLOGY, vol. 44, no. 6, June 1998 (1998-06-01), pages 514 - 520, XP002985044 *

Also Published As

Publication number Publication date
US20080167246A1 (en) 2008-07-10
WO2004091438A2 (en) 2004-10-28
WO2004091438B1 (en) 2005-05-06
US20110212885A1 (en) 2011-09-01
US7939501B2 (en) 2011-05-10

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