WO2004091361A3 - Optical capsule and spectroscopic method for treating or diagnosing the intestinal tract - Google Patents

Optical capsule and spectroscopic method for treating or diagnosing the intestinal tract Download PDF

Info

Publication number
WO2004091361A3
WO2004091361A3 PCT/US2003/041352 US0341352W WO2004091361A3 WO 2004091361 A3 WO2004091361 A3 WO 2004091361A3 US 0341352 W US0341352 W US 0341352W WO 2004091361 A3 WO2004091361 A3 WO 2004091361A3
Authority
WO
WIPO (PCT)
Prior art keywords
capsule
intestinal tract
diagnosing
treating
spectroscopic method
Prior art date
Application number
PCT/US2003/041352
Other languages
French (fr)
Other versions
WO2004091361A2 (en
Inventor
Mir A Imran
Oliver K Colliou
Ted W Layman
Sharon L Lake
Original Assignee
Entrack Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entrack Inc filed Critical Entrack Inc
Priority to AU2003304041A priority Critical patent/AU2003304041A1/en
Publication of WO2004091361A2 publication Critical patent/WO2004091361A2/en
Publication of WO2004091361A3 publication Critical patent/WO2004091361A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/07—Endoradiosondes
    • A61B5/073—Intestinal transmitters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/041—Capsule endoscopes for imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0031—Implanted circuitry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
    • A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
    • A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
    • A61B5/064—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222—Evaluating particular parts, e.g. particular organs
    • A61B5/4255—Intestines, colon or appendix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0833—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/025—Digital circuitry features of electrotherapy devices, e.g. memory, clocks, processors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002—Operational features of endoscopes
    • A61B1/00011—Operational features of endoscopes characterised by signal transmission
    • A61B1/00016—Operational features of endoscopes characterised by signal transmission using wireless means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002—Operational features of endoscopes
    • A61B1/00025—Operational features of endoscopes characterised by power management
    • A61B1/00036—Means for power saving, e.g. sleeping mode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/03—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
    • A61B5/036—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs by means introduced into body tracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0507—Electrodes for the digestive system
    • A61N1/0509—Stomach and intestinal electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/06—Electrodes for high-frequency therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37205—Microstimulators, e.g. implantable through a cannula

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Human Computer Interaction (AREA)
  • Endocrinology (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

A device (160, 110) and method for mapping, diagnosing and treating disorders or other diseases, disorders or conditions (e.g., bleeding, ischemic or necrotic tissue, and presence of certain chemicals or substances) of the intestinal tract is provided using a capsule (110) passing through the intestinal tract and sensing optical characteristics as the capsule (110) passes through. Further, a capsule tracking system (160) is provided for tracking a capsule's (110) location along the length of an intestinal tract as various treatment and/or sensing modalities are employed. In one variation, an acoustic signal is used to determine the location of the capsule (110). A map of optical characteristics may be derived from the pass of a capsule (110) to diagnose the disorder or disease. The capsule (110) or subsequently passed capsules may treat, further diagnose or mark the intestinal tract at a determined location along its length.
PCT/US2003/041352 2002-12-24 2003-12-22 Optical capsule and spectroscopic method for treating or diagnosing the intestinal tract WO2004091361A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003304041A AU2003304041A1 (en) 2002-12-24 2003-12-22 Optical capsule and spectroscopic method for treating or diagnosing the intestinal tract

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43628502P 2002-12-24 2002-12-24
US60/436,285 2002-12-24

Publications (2)

Publication Number Publication Date
WO2004091361A2 WO2004091361A2 (en) 2004-10-28
WO2004091361A3 true WO2004091361A3 (en) 2006-06-08

Family

ID=33299565

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/041352 WO2004091361A2 (en) 2002-12-24 2003-12-22 Optical capsule and spectroscopic method for treating or diagnosing the intestinal tract

Country Status (2)

Country Link
AU (1) AU2003304041A1 (en)
WO (1) WO2004091361A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8442841B2 (en) 2005-10-20 2013-05-14 Matacure N.V. Patient selection method for assisting weight loss
US8915867B2 (en) 2001-06-26 2014-12-23 Entrack, Inc. System for marking a location for treatment within the gastrointestinal tract
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6600953B2 (en) 2000-12-11 2003-07-29 Impulse Dynamics N.V. Acute and chronic electrical signal therapy for obesity
US9821158B2 (en) 2005-02-17 2017-11-21 Metacure Limited Non-immediate effects of therapy
DE102005032140A1 (en) * 2005-07-07 2007-01-11 Siemens Ag Capsule to be used for magnetic wireless diagnosis of gastrointestinal tract, comprises light emitting diode
RU2008143010A (en) * 2006-03-30 2010-05-10 Конинклейке Филипс Электроникс Н.В. (Nl) INCREASING VOLUME OF THE GASTRIC TABLET AND METHOD OF ITS APPLICATION
EP2046434B1 (en) * 2006-06-23 2012-02-08 Koninklijke Philips Electronics N.V. Medicament delivery system
EP2196132B1 (en) 2007-10-01 2015-08-26 Olympus Corporation Capsule type medical apparatus and capsule type medical system
DE102009030171A1 (en) * 2009-06-24 2010-12-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. An imaging apparatus and method for detecting irregularities in cavities of objects
US20120022338A1 (en) * 2010-05-28 2012-01-26 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for analyzing information regarding cardiovascular diseases and functions
US10264995B2 (en) * 2013-12-04 2019-04-23 Obalon Therapeutics, Inc. Systems and methods for locating and/or characterizing intragastric devices
WO2018011431A1 (en) * 2016-07-15 2018-01-18 Koninklijke Philips N.V. Temporarily implantable sensing marker
US20200375438A1 (en) * 2019-05-31 2020-12-03 The Boeing Company Optical Fiber Sensor System
CN111743512A (en) * 2020-06-28 2020-10-09 中国医学科学院北京协和医院 Novel intestinal function dynamic monitor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020042562A1 (en) * 2000-09-27 2002-04-11 Gavriel Meron Immobilizable in vivo sensing device
US20030139661A1 (en) * 2001-01-22 2003-07-24 Yoav Kimchy Ingestible device
US6950690B1 (en) * 1998-10-22 2005-09-27 Given Imaging Ltd Method for delivering a device to a target location

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6950690B1 (en) * 1998-10-22 2005-09-27 Given Imaging Ltd Method for delivering a device to a target location
US20020042562A1 (en) * 2000-09-27 2002-04-11 Gavriel Meron Immobilizable in vivo sensing device
US20030139661A1 (en) * 2001-01-22 2003-07-24 Yoav Kimchy Ingestible device

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US8915867B2 (en) 2001-06-26 2014-12-23 Entrack, Inc. System for marking a location for treatment within the gastrointestinal tract
US9167990B2 (en) 2001-06-26 2015-10-27 Entrack, Inc. Optical capsule and spectroscopic method for treating and diagnosing the intestinal tract
US9414768B2 (en) 2001-06-26 2016-08-16 Entrack, Inc. Capsule and method for treating or diagnosing conditions or diseases of the intestinal tract
US9456774B2 (en) 2001-06-26 2016-10-04 Entrack, Inc. System for marking a location for treatment within the gastrointestinal tract
US8442841B2 (en) 2005-10-20 2013-05-14 Matacure N.V. Patient selection method for assisting weight loss
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy

Also Published As

Publication number Publication date
WO2004091361A2 (en) 2004-10-28
AU2003304041A1 (en) 2004-11-04
AU2003304041A8 (en) 2004-11-04

Similar Documents

Publication Publication Date Title
WO2005096937A3 (en) Capsule and method for treating or diagnosing conditions or diseases of the intestinal tract
WO2004091361A3 (en) Optical capsule and spectroscopic method for treating or diagnosing the intestinal tract
WO2003075745A3 (en) Detection, diagnosis, and monitoring of a medical condition or disease with artificial olfactometry
DE59705683D1 (en) IMMUNOLOGICAL DETECTION METHOD OF ANTIBODIES TARGETED AGAINST TISSUE TRANSGLUTAMINASE (tTG), USE OF tTG FOR DIAGNOSIS AND THERAPY CONTROL, AND ORAL PHARMACEUTICAL AGENT CONTAINING tTG
WO2002102227A3 (en) Gastric treatment and diagnosis device and method
WO2001087138A3 (en) Method and apparatus for detection of acid reflux
WO2005098429A3 (en) System and method for real-time diagnosis, treatment, and therapeutic drug monitoring
WO2004047675A3 (en) Apparatus and method for palpograhic chacterization of vulnerable plaque and other biological tissue
WO2001065263A3 (en) Sensor device for diarrhea diagnosis using fecal markers
DE69938662D1 (en) TRACE DETECTION OF ANALYTES BY ARTIFICIAL OLFAKTOMETRY
CA2472156A1 (en) System and method of assessment of neurological conditions using eeg bispectrum
WO2000035473A3 (en) Methods for detection and use of differentially expressed genes in disease states
WO2004032720A3 (en) Multi-modal system for detection and control of changes in brain state
DE69637553D1 (en) Device for detecting an analyte and administering a therapeutic substance
WO2001070117A3 (en) Pressure sensor for therapeutic delivery device and method
WO2007149985A3 (en) Assessing dementia and dementia-type disorders
NO20034786L (en) Procedure for differential diagnosis of Alzheimer's dementia and device therefor
ATE257671T1 (en) MEDICAL DEVICE FOR DIAGNOSING CARTILAGE DESTRUCTION USING SPATIAL MAPPING OF PRESSURE-INDUCED POTENTIALS
DE602005012250D1 (en) NONINVASIVE MONITORING SYSTEM FOR MICROCIRCULATION
DE50103907D1 (en) Uses of aldose-1-epimerase (mutarotase) for the diagnosis of inflammatory diseases and sepsis
FR2831450B1 (en) ACTIVE IMPLANTABLE MEDICAL DEVICE FOR THE TREATMENT OF HEART RATE DISORDERS, INCLUDING IMPROVED MEANS FOR DETECTING ATRIAL ARRHYTHMIAS
WO2003070883A3 (en) Methods and compositions for treating aids and hiv-related disorders using 1414, 1481, 1553, 34021, 1720, 1683, 1552, 1682, 1675, 12825, 9952, 5816, 10002, 1611, 1371, 14324, 126, 270, 312, 167, 326, 18926, 6747, 1793, 1784, or 2045 molecules.
WO2004072242A3 (en) Screening of compounds for hematological disorder treatment
RU2257152C2 (en) Method for predicting opisthorchiasis
Patrick Shoenut et al. Ambulatory esophageal pH testing: Referral patterns, indication, and treatment in a Canadian teaching hospital

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP