WO2004087095A3 - Osmotic controlled release device containing zafirlukast and an h1-antagonist - Google Patents

Osmotic controlled release device containing zafirlukast and an h1-antagonist Download PDF

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Publication number
WO2004087095A3
WO2004087095A3 PCT/CR2004/000004 CR2004000004W WO2004087095A3 WO 2004087095 A3 WO2004087095 A3 WO 2004087095A3 CR 2004000004 W CR2004000004 W CR 2004000004W WO 2004087095 A3 WO2004087095 A3 WO 2004087095A3
Authority
WO
WIPO (PCT)
Prior art keywords
antagonist
zafirlukast
controlled release
release device
device containing
Prior art date
Application number
PCT/CR2004/000004
Other languages
Spanish (es)
French (fr)
Other versions
WO2004087095A2 (en
Inventor
Juan A Vergez
Joaquina Faour
Marcelo F Befumo
Original Assignee
Osmotica Costa Rica Sa
Juan A Vergez
Joaquina Faour
Marcelo F Befumo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osmotica Costa Rica Sa, Juan A Vergez, Joaquina Faour, Marcelo F Befumo filed Critical Osmotica Costa Rica Sa
Publication of WO2004087095A2 publication Critical patent/WO2004087095A2/en
Publication of WO2004087095A3 publication Critical patent/WO2004087095A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Abstract

The invention relates to a controlled release device, e.g. an osmotic device, which releases zafirlukast in a controlled manner and which releases a H1 antagonist in a rapid and/or immediate manner. A wide range of antihistamine H1 antagonists, particularly loratadine, can be used in the inventive device. Specific embodiments of the invention comprise osmotic devices which release zafirlukast and a H1 antagonist in a controlled manner from the nucleus over an extended period of time. The aforementioned devices can be used for the treatment of allergic reactions, inflammation and asthma.
PCT/CR2004/000004 2003-03-31 2004-03-30 Osmotic controlled release device containing zafirlukast and an h1-antagonist WO2004087095A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45909803P 2003-03-31 2003-03-31
US60/459,098 2003-03-31

Publications (2)

Publication Number Publication Date
WO2004087095A2 WO2004087095A2 (en) 2004-10-14
WO2004087095A3 true WO2004087095A3 (en) 2005-07-21

Family

ID=33131864

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CR2004/000004 WO2004087095A2 (en) 2003-03-31 2004-03-30 Osmotic controlled release device containing zafirlukast and an h1-antagonist

Country Status (1)

Country Link
WO (1) WO2004087095A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0620863A8 (en) 2005-12-29 2018-01-16 Osmotica Kereskedelmi Es Szolgaltato Kft triple-release combination tablet
CN104958279A (en) * 2015-06-27 2015-10-07 万特制药(海南)有限公司 Loratadine oral quickly-soluble film and preparation method thereof

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4008719A (en) * 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
WO1997028797A1 (en) * 1996-02-08 1997-08-14 Merck & Co., Inc. Method of treatment and pharmaceutical composion
WO1999032125A1 (en) * 1997-12-23 1999-07-01 Schering Corporation Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine
US20020102305A1 (en) * 2000-01-13 2002-08-01 Joaquina Faour Osmotic device containing pseudoephedrine and an H1antagonist
CA2337571A1 (en) * 2001-02-20 2002-08-20 Asta Medica Aktiengesellschaft Antihistamine leukotriene combinations
WO2002080916A1 (en) * 2001-04-03 2002-10-17 Kaura Sita R Composition and method for the treatment of respiratory disease
US20030044457A1 (en) * 2001-07-17 2003-03-06 Joaquina Faour Drug delivery device containing oseltamivir and an H1 antagonist
US20030055077A1 (en) * 2000-04-12 2003-03-20 Jones Thomas R. Method and compositions for the treatment of allergic conditions using pgd2 receptor antagonists
WO2003068186A1 (en) * 2002-02-11 2003-08-21 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4008719A (en) * 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
WO1997028797A1 (en) * 1996-02-08 1997-08-14 Merck & Co., Inc. Method of treatment and pharmaceutical composion
WO1999032125A1 (en) * 1997-12-23 1999-07-01 Schering Corporation Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine
US20020102305A1 (en) * 2000-01-13 2002-08-01 Joaquina Faour Osmotic device containing pseudoephedrine and an H1antagonist
US20030055077A1 (en) * 2000-04-12 2003-03-20 Jones Thomas R. Method and compositions for the treatment of allergic conditions using pgd2 receptor antagonists
CA2337571A1 (en) * 2001-02-20 2002-08-20 Asta Medica Aktiengesellschaft Antihistamine leukotriene combinations
WO2002080916A1 (en) * 2001-04-03 2002-10-17 Kaura Sita R Composition and method for the treatment of respiratory disease
US20030044457A1 (en) * 2001-07-17 2003-03-06 Joaquina Faour Drug delivery device containing oseltamivir and an H1 antagonist
WO2003068186A1 (en) * 2002-02-11 2003-08-21 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents

Also Published As

Publication number Publication date
WO2004087095A2 (en) 2004-10-14

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