WO2004078134A3 - Biologic replacement for fibrin clot - Google Patents

Biologic replacement for fibrin clot Download PDF

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Publication number
WO2004078134A3
WO2004078134A3 PCT/US2004/006392 US2004006392W WO2004078134A3 WO 2004078134 A3 WO2004078134 A3 WO 2004078134A3 US 2004006392 W US2004006392 W US 2004006392W WO 2004078134 A3 WO2004078134 A3 WO 2004078134A3
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WO
WIPO (PCT)
Prior art keywords
fibrin clot
biologic replacement
biologic
replacement
methods
Prior art date
Application number
PCT/US2004/006392
Other languages
French (fr)
Other versions
WO2004078134A2 (en
Inventor
Martha M Murray
Michael F Murray
Jennifer J Marler
Kurt P Spindler
Aeonor J Sawyer
Arnulf Pascher
Steven Ghivizzani
Christopher Evans
Original Assignee
Brigham & Womens Hospital
Martha M Murray
Michael F Murray
Jennifer J Marler
Kurt P Spindler
Aeonor J Sawyer
Arnulf Pascher
Steven Ghivizzani
Christopher Evans
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital, Martha M Murray, Michael F Murray, Jennifer J Marler, Kurt P Spindler, Aeonor J Sawyer, Arnulf Pascher, Steven Ghivizzani, Christopher Evans filed Critical Brigham & Womens Hospital
Priority to EP04716849A priority Critical patent/EP1610754A2/en
Priority to US10/548,159 priority patent/US20080031923A1/en
Publication of WO2004078134A2 publication Critical patent/WO2004078134A2/en
Publication of WO2004078134A3 publication Critical patent/WO2004078134A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/04—Uses of viruses as vector in vivo
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/06—Uses of viruses as vector in vitro

Abstract

The invention provides methods and devices for repairing a ruptured ligament, meniscus, cartilage, tendon, and bone. Methods and products for delivering nucleic acids to damaged tissue are also disclosed.
PCT/US2004/006392 1999-06-22 2004-03-03 Biologic replacement for fibrin clot WO2004078134A2 (en)

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EP04716849A EP1610754A2 (en) 2003-03-03 2004-03-03 Biologic replacement for fibrin clot
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US20040059416A1 (en) 2004-03-25

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