WO2004065583A3 - Gene expression markers for breast cancer prognosis - Google Patents
Gene expression markers for breast cancer prognosis Download PDFInfo
- Publication number
- WO2004065583A3 WO2004065583A3 PCT/US2004/000985 US2004000985W WO2004065583A3 WO 2004065583 A3 WO2004065583 A3 WO 2004065583A3 US 2004000985 W US2004000985 W US 2004000985W WO 2004065583 A3 WO2004065583 A3 WO 2004065583A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- breast cancer
- gene expression
- cancer prognosis
- expression markers
- prognosis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15190640.1A EP3059322B1 (en) | 2003-01-15 | 2004-01-14 | Gene expression markers for breast cancer prognosis |
EP04702177A EP1587957B1 (en) | 2003-01-15 | 2004-01-14 | Gene expression markers for breast cancer prognosis |
JP2006500964A JP4723472B2 (en) | 2003-01-15 | 2004-01-14 | Gene expression markers for breast cancer prognosis |
AT04702177T ATE470723T1 (en) | 2003-01-15 | 2004-01-14 | GENE EXPRESSION MARKERS FOR BREAST CANCER PROGNOSIS |
DE602004027600T DE602004027600D1 (en) | 2003-01-15 | 2004-01-14 | GENE EXPRESSION MARKERS FOR THE PROGNOSIS OF BREAST CANCER |
DK04702177.9T DK1587957T3 (en) | 2003-01-15 | 2004-01-14 | Gene expression marker for breast cancer prognosis |
AU2004205878A AU2004205878B2 (en) | 2003-01-15 | 2004-01-14 | Gene expression markers for breast cancer prognosis |
CA2513117A CA2513117C (en) | 2003-01-15 | 2004-01-14 | Gene expression markers for breast cancer prognosis |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44086103P | 2003-01-15 | 2003-01-15 | |
US60/440,861 | 2003-01-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004065583A2 WO2004065583A2 (en) | 2004-08-05 |
WO2004065583A3 true WO2004065583A3 (en) | 2005-03-03 |
Family
ID=32771871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/000985 WO2004065583A2 (en) | 2003-01-15 | 2004-01-14 | Gene expression markers for breast cancer prognosis |
Country Status (11)
Country | Link |
---|---|
US (7) | US20040231909A1 (en) |
EP (4) | EP2230318A1 (en) |
JP (1) | JP4723472B2 (en) |
AT (1) | ATE470723T1 (en) |
AU (2) | AU2004205878B2 (en) |
CA (5) | CA3013889A1 (en) |
DE (1) | DE602004027600D1 (en) |
DK (3) | DK2230319T3 (en) |
ES (3) | ES2725892T3 (en) |
HK (1) | HK1148783A1 (en) |
WO (1) | WO2004065583A2 (en) |
Families Citing this family (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6984522B2 (en) | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
US8044259B2 (en) | 2000-08-03 | 2011-10-25 | The Regents Of The University Of Michigan | Determining the capability of a test compound to affect solid tumor stem cells |
US20060062786A1 (en) * | 2000-11-08 | 2006-03-23 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US20090226429A1 (en) * | 2001-05-25 | 2009-09-10 | Human Genome Sciences, Inc. | Antibodies That Immunospecifically Bind to TRAIL Receptors |
US7361341B2 (en) * | 2001-05-25 | 2008-04-22 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to trail receptors |
US20050214209A1 (en) * | 2001-05-25 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US7348003B2 (en) | 2001-05-25 | 2008-03-25 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors |
US20050129616A1 (en) * | 2001-05-25 | 2005-06-16 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US20030180296A1 (en) * | 2001-12-20 | 2003-09-25 | Theodora Salcedo | Antibodies that immunospecifically bind to trail receptors |
EP2258872B1 (en) * | 2002-03-13 | 2013-08-14 | Genomic Health, Inc. | Gene expression profiling in biopsied tumor tissues |
US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
CA3061769C (en) * | 2003-06-24 | 2021-10-26 | Genomic Health, Inc. | Methods of predicting the likelihood of long-term survival of a human patient with node-negative, estrogen receptor (er) positive, invasive ductal breast cancer without the recurrence of breast cancer |
WO2005008213A2 (en) | 2003-07-10 | 2005-01-27 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
US20060003391A1 (en) * | 2003-08-11 | 2006-01-05 | Ring Brian Z | Reagents and methods for use in cancer diagnosis, classification and therapy |
US20050112622A1 (en) * | 2003-08-11 | 2005-05-26 | Ring Brian Z. | Reagents and methods for use in cancer diagnosis, classification and therapy |
EP1737980A2 (en) | 2004-04-09 | 2007-01-03 | Fondazione IRCCS Istituto Nazionale dei Tumori | Gene expression markers for predicting response to chemotherapy |
US20080131916A1 (en) * | 2004-08-10 | 2008-06-05 | Ring Brian Z | Reagents and Methods For Use In Cancer Diagnosis, Classification and Therapy |
US20100035240A1 (en) * | 2004-08-10 | 2010-02-11 | Cardiff Biologicals Limited | Methods and kit for the prognosis of breast cancer |
AU2005289756B2 (en) * | 2004-09-22 | 2011-10-13 | Tripath Imaging, Inc. | Methods and computer program products for analysis and optimization of marker candidates for cancer prognosis |
US8065093B2 (en) | 2004-10-06 | 2011-11-22 | Agency For Science, Technology, And Research | Methods, systems, and compositions for classification, prognosis, and diagnosis of cancers |
JP5020088B2 (en) * | 2004-11-05 | 2012-09-05 | ジェノミック ヘルス, インコーポレイテッド | Predicting response to chemotherapy using gene expression markers |
DK1815014T3 (en) * | 2004-11-05 | 2012-06-18 | Genomic Health Inc | Molecular indicators of breast cancer prognosis and prediction of treatment response |
ZA200704796B (en) * | 2004-12-07 | 2008-11-26 | Genentech Inc | Selecting patients for therapy with a HER inhibitor |
EP3698807A1 (en) | 2005-01-21 | 2020-08-26 | Genentech, Inc. | Fixed dosing of her antibodies |
AU2006216732C1 (en) * | 2005-02-23 | 2017-07-20 | Genentech, Inc. | Extending time to disease progression or survival in cancer patients using a HER dimerization inhibitor |
US20080275652A1 (en) * | 2005-05-13 | 2008-11-06 | Universite Libre De Bruxelles | Gene-based algorithmic cancer prognosis |
JP2006316040A (en) | 2005-05-13 | 2006-11-24 | Genentech Inc | Herceptin(r) adjuvant treatment |
US20070099209A1 (en) * | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
ATE520979T1 (en) * | 2005-08-24 | 2011-09-15 | Bristol Myers Squibb Co | BIOMARRKERS AND METHODS FOR DETERMINING SENSITIVITY TO MODULATORS OF THE EGF (EPIDERMAL GROWTH FACTOR) RECEPTOR |
JP5129149B2 (en) | 2005-10-31 | 2013-01-23 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | Compositions and methods for treating and diagnosing cancer |
US7662580B2 (en) | 2005-11-10 | 2010-02-16 | Aurelium Biopharma Inc. | Tissue diagnostics for breast cancer |
TW200731980A (en) * | 2005-12-29 | 2007-09-01 | Alcon Mfg Ltd | RNAi-mediated inhibition of HIF1A for treatment of ocular angiogenesis |
WO2007123772A2 (en) * | 2006-03-31 | 2007-11-01 | Genomic Health, Inc. | Genes involved in estrogen metabolism |
ES2539042T3 (en) * | 2006-06-02 | 2015-06-25 | Glaxosmithkline Biologicals S.A. | Identification procedure of whether a patient will respond to immunotherapy or not |
WO2008063521A2 (en) * | 2006-11-13 | 2008-05-29 | The General Hospital Corporation | Gene-based clinical scoring system |
WO2008092002A2 (en) | 2007-01-24 | 2008-07-31 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing pancreatic cancer |
WO2008109440A2 (en) | 2007-03-02 | 2008-09-12 | Genentech, Inc. | Predicting response to a her dimerisation inhibitor based on low her3 expression |
BRPI0809366B8 (en) | 2007-03-28 | 2021-05-25 | Harvard College | substantially alpha-helical polypeptide, method for manufacturing same, amino acid and pharmaceutical composition |
WO2008150512A2 (en) * | 2007-06-04 | 2008-12-11 | University Of Louisville Research Foundation, Inc. | Methods for identifying an increased likelihood of recurrence of breast cancer |
US9551033B2 (en) * | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
WO2008154249A2 (en) * | 2007-06-08 | 2008-12-18 | Genentech, Inc. | Gene expression markers of tumor resistance to her2 inhibitor treatment |
AU2008289148A1 (en) * | 2007-08-16 | 2009-02-26 | Aventis Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
GB0720113D0 (en) * | 2007-10-15 | 2007-11-28 | Cambridge Cancer Diagnostics L | Diagnostic, prognostic and predictive testing for cancer |
WO2009067655A2 (en) * | 2007-11-21 | 2009-05-28 | University Of Florida Research Foundation, Inc. | Methods of feature selection through local learning; breast and prostate cancer prognostic markers |
EP2065475A1 (en) * | 2007-11-30 | 2009-06-03 | Siemens Healthcare Diagnostics GmbH | Method for therapy prediction in tumors having irregularities in the expression of at least one VEGF ligand and/or at least one ErbB-receptor |
US20110130296A1 (en) * | 2008-03-14 | 2011-06-02 | The Regents Of The University Of California | Multi-gene classifiers and prognostic indicators for cancers |
BRPI0812682A2 (en) | 2008-06-16 | 2010-06-22 | Genentech Inc | metastatic breast cancer treatment |
US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
US20100221752A2 (en) * | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
WO2010045234A1 (en) * | 2008-10-14 | 2010-04-22 | University Of Louisville Research Foundation, Inc. | Methods of optimizing treatment of estrogen-receptor positive breast cancers |
GB0821787D0 (en) * | 2008-12-01 | 2009-01-07 | Univ Ulster | A genomic-based method of stratifying breast cancer patients |
US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
US20120225789A1 (en) * | 2009-05-29 | 2012-09-06 | Baylor College Of Medicine | Dna repair or brca1-like gene signature |
JP5705836B2 (en) | 2009-05-29 | 2015-04-22 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | Modulators for HER2 signaling in gastric cancer patients expressing HER2 |
US20100316639A1 (en) | 2009-06-16 | 2010-12-16 | Genentech, Inc. | Biomarkers for igf-1r inhibitor therapy |
EP2275569A1 (en) * | 2009-07-17 | 2011-01-19 | Centre Leon Berard | ZNF217 a new prognostic and predictive biomarker of recurrent, invasive and metastatic phenotypes in cancer |
GB0917457D0 (en) * | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
DK2504451T3 (en) * | 2009-11-23 | 2019-08-05 | Genomic Health Inc | Methods for predicting the clinical course of cancer |
WO2011088137A2 (en) * | 2010-01-12 | 2011-07-21 | H. Lee Moffitt Cancer Center & Research Institute | Bad pathway gene signature |
US20130143753A1 (en) * | 2010-03-01 | 2013-06-06 | Adelbio | Methods for predicting outcome of breast cancer, and/or risk of relapse, response or survival of a patient suffering therefrom |
WO2011146568A1 (en) | 2010-05-19 | 2011-11-24 | Genentech, Inc. | Predicting response to a her inhibitor |
CA2804391A1 (en) | 2010-07-07 | 2012-01-12 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
SG186953A1 (en) | 2010-07-09 | 2013-02-28 | Somalogic Inc | Lung cancer biomarkers and uses thereof |
CN106198980B (en) | 2010-08-13 | 2018-09-07 | 私募蛋白质体公司 | Cancer of pancreas biomarker and application thereof |
US8859723B2 (en) | 2010-08-13 | 2014-10-14 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
EP2611941A4 (en) | 2010-08-30 | 2014-01-22 | Myriad Genetics Inc | Gene signatures for cancer diagnosis and prognosis |
US10011876B2 (en) | 2010-11-23 | 2018-07-03 | Krisani Biosciences Pvt. Ltd | Method and system for prognosis and treatment of diseases using portfolio of genes |
WO2012109233A2 (en) * | 2011-02-07 | 2012-08-16 | Board Of Regents, The University Of Texas System | Methods for predicting recurrence risk in breast cancer patients |
CN108929375A (en) | 2011-10-18 | 2018-12-04 | 爱勒让治疗公司 | Peptidomimetic macrocyclic compound |
WO2013070521A1 (en) * | 2011-11-08 | 2013-05-16 | Genomic Health, Inc. | Method of predicting breast cancer prognosis |
WO2013083810A1 (en) | 2011-12-09 | 2013-06-13 | F. Hoffmann-La Roche Ag | Identification of non-responders to her2 inhibitors |
US8987414B2 (en) | 2012-02-15 | 2015-03-24 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
WO2013170174A1 (en) * | 2012-05-10 | 2013-11-14 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Method of diagnosing, treating and determining progression and survival of cancer cells using bcl-2 antagonist of cell death (bad) pathway gene signature |
WO2013188600A1 (en) | 2012-06-12 | 2013-12-19 | Washington University | Copy number aberration driven endocrine response gene signature |
JP6526563B2 (en) | 2012-11-01 | 2019-06-05 | エイルロン セラピューティクス,インコーポレイテッド | Disubstituted amino acids and methods for their preparation and use |
EP4190918A1 (en) | 2012-11-16 | 2023-06-07 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
MX363188B (en) | 2012-11-30 | 2019-03-13 | Hoffmann La Roche | Identification of patients in need of pd-l1 inhibitor cotherapy. |
CA2896899A1 (en) | 2013-01-18 | 2014-07-24 | Ellis KLINE | Selective glycosidase regimen for immune programming and treatment of cancer |
WO2014124454A1 (en) | 2013-02-11 | 2014-08-14 | Katerina Gurova | Use of facilitates chromatin transcription complex (fact) in cancer |
CN103465779B (en) * | 2013-09-17 | 2015-12-09 | 哈尔滨工程大学 | Omnidirectional with double engines 4 wheel driven walking mechanism |
CN103558382B (en) * | 2013-10-28 | 2015-11-18 | 深圳市第二人民医院 | The application of CCNE1 gene on detecting in bladder transitional cell carcinoma |
CN103558383B (en) * | 2013-10-28 | 2015-11-18 | 深圳市第二人民医院 | The application of ALDH2 gene on detecting in bladder transitional cell carcinoma |
KR20150088433A (en) | 2014-01-24 | 2015-08-03 | 삼성전자주식회사 | Biomarker TFF1 for predicting effect of a c-Met inhibitor |
EP3623482A1 (en) | 2014-05-13 | 2020-03-18 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
US10633710B2 (en) | 2014-08-15 | 2020-04-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods for characterizing cancer |
SG10201902594QA (en) | 2014-09-24 | 2019-04-29 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof |
US10905739B2 (en) | 2014-09-24 | 2021-02-02 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
ES2833543T3 (en) | 2014-10-24 | 2021-06-15 | Koninklijke Philips Nv | Evaluation of the activity of the TGF cell signaling pathway using mathematical models of target gene expression |
CA2965217A1 (en) | 2014-10-24 | 2016-04-28 | Koninklijke Philips N.V. | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities |
AU2015334842B2 (en) | 2014-10-24 | 2022-02-17 | Koninklijke Philips N.V. | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities |
MX2017011834A (en) | 2015-03-20 | 2018-04-11 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof. |
EP3073268A1 (en) * | 2015-03-27 | 2016-09-28 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Biomarker panel for diagnosing cancer |
CN108138237B (en) | 2015-08-14 | 2022-04-05 | 皇家飞利浦有限公司 | Assessment of NFkB cell signaling pathway activity using mathematical modeling of target gene expression |
CN107058523A (en) * | 2017-03-21 | 2017-08-18 | 温州迪安医学检验所有限公司 | A kind of genetic test primer of breast carcinoma recurring risk assessment 21 and its application |
EP3461915A1 (en) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression |
EP3502279A1 (en) | 2017-12-20 | 2019-06-26 | Koninklijke Philips N.V. | Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression |
CN110045120A (en) * | 2018-01-15 | 2019-07-23 | 长庚医疗财团法人基隆长庚纪念医院 | Detect detection kit and its application of the concentration of WISP1 in biological sample in preparation for breast cancer screening and detecting recurrence |
WO2020013355A1 (en) * | 2018-07-10 | 2020-01-16 | 서울대학교산학협력단 | Composition for predicting prognosis of malignant phyllodes tumor and kit comprising same |
EP4013896A4 (en) * | 2019-08-12 | 2023-09-20 | Baylor College of Medicine | Proteogenomic methods for diagnosing cancer |
CN113862363A (en) * | 2021-10-27 | 2021-12-31 | 中山大学附属第一医院 | Application of immune related gene in kit and system for breast cancer prognosis |
CN114480650A (en) * | 2022-02-08 | 2022-05-13 | 深圳市陆为生物技术有限公司 | Marker and model for predicting three-negative breast cancer clinical prognosis recurrence risk |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6001583A (en) * | 1994-03-07 | 1999-12-14 | New York University Medical Center | Methods for disrupting GRB-7 complexes |
WO2000055173A1 (en) * | 1999-03-12 | 2000-09-21 | Human Genome Sciences, Inc. | Human breast and ovarian cancer associated gene sequences and polypeptides |
WO2001075160A1 (en) * | 2000-03-31 | 2001-10-11 | Vysis, Inc. | Patient stratification for cancer therapy based on genomic dna microarray analysis |
WO2002010436A2 (en) * | 2000-07-28 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Prognostic classification of breast cancer |
WO2002046467A2 (en) * | 2000-12-08 | 2002-06-13 | Ipsogen | Gene expression profiling of primary breast carcinomas using arrays of candidate genes |
WO2002059271A2 (en) * | 2001-01-25 | 2002-08-01 | Gene Logic, Inc. | Gene expression profiles in breast tissue |
WO2003078662A1 (en) * | 2002-03-13 | 2003-09-25 | Genomic Health | Gene expression profiling in biopsied tumor tissues |
Family Cites Families (98)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1252046A (en) | 1982-11-04 | 1989-04-04 | Martin J. Cline | Methods for oncogenic detection |
USRE35491E (en) | 1982-11-04 | 1997-04-08 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
US4699877A (en) | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
US7838216B1 (en) | 1986-03-05 | 2010-11-23 | The United States Of America, As Represented By The Department Of Health And Human Services | Human gene related to but distinct from EGF receptor gene |
US5015568A (en) | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
US5202429A (en) | 1986-07-09 | 1993-04-13 | The Wistar Institute | DNA molecules having human BCL-2 gene sequences |
US4968603A (en) | 1986-12-31 | 1990-11-06 | The Regents Of The University Of California | Determination of status in neoplastic disease |
US5831066A (en) | 1988-12-22 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Regulation of bcl-2 gene expression |
US5922855A (en) * | 1993-12-17 | 1999-07-13 | Oregon Health Sciences University | Mammalian DNA mismatch repair genes MLH1 and PMS1 |
US7625697B2 (en) * | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
US5858678A (en) | 1994-08-02 | 1999-01-12 | St. Louis University | Apoptosis-regulating proteins |
US5830753A (en) | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
US6218529B1 (en) * | 1995-07-31 | 2001-04-17 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer |
US5882864A (en) | 1995-07-31 | 1999-03-16 | Urocor Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate disease |
DE69635740T2 (en) | 1995-12-18 | 2006-09-14 | Sugen, Inc., South San Francisco | DIAGNOSIS AND TREATMENT OF AURA-1 AND / OR AUR-2 ASSOCIATED DISEASES |
US6716575B2 (en) | 1995-12-18 | 2004-04-06 | Sugen, Inc. | Diagnosis and treatment of AUR1 and/or AUR2 related disorders |
US5670325A (en) | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
US5741650A (en) | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
US5821082A (en) | 1996-05-23 | 1998-10-13 | St. Louis University Health Sciences Center | Anti-proliferation domain of a human Bcl-2 and DNA encoding the same |
US6143529A (en) | 1996-08-14 | 2000-11-07 | Exact Laboratories, Inc. | Methods for improving sensitivity and specificity of screening assays |
US5928870A (en) | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US6146828A (en) | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
US6100029A (en) | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
US6020137A (en) | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US6203993B1 (en) | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
US5952178A (en) | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
US5861278A (en) | 1996-11-01 | 1999-01-19 | Genetics Institute, Inc. | HNF3δ compositions |
KR100645448B1 (en) | 1996-11-20 | 2006-11-13 | 예일 유니버시티 | Survivin, a protein that inhibit cellular apoptosis, and its modulation |
US5830665A (en) | 1997-03-03 | 1998-11-03 | Exact Laboratories, Inc. | Contiguous genomic sequence scanning |
US6033893A (en) | 1997-06-26 | 2000-03-07 | Incyte Pharmaceuticals, Inc. | Human cathepsin |
WO1999002714A1 (en) | 1997-07-07 | 1999-01-21 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
WO1999020752A1 (en) * | 1997-10-21 | 1999-04-29 | The University Court Of The University Of Glasgow | JMY, A CO-ACTIVATOR FOR p300/CBP, NUCLEIC ACID ENCODING JMY AND USES THEREOF |
CA2318789C (en) * | 1998-02-25 | 2011-05-10 | The United States Of America As Represented By The Secretary Department Of Health And Human Services | Cellular arrays for rapid molecular profiling |
US6020135A (en) | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
AU4158799A (en) | 1998-06-06 | 1999-12-30 | Genostic Pharma Limited | Probes used for genetic filing |
AU766544B2 (en) | 1998-06-06 | 2003-10-16 | Genostic Pharma Limited | Probes used for genetic profiling |
US6696558B2 (en) | 1998-09-09 | 2004-02-24 | The Burnham Institute | Bag proteins and nucleic acid molecules encoding them |
EP1115737A4 (en) | 1998-09-23 | 2004-11-24 | Cleveland Clinic Foundation | Novel interferon stimulated and repressed genes |
US6251601B1 (en) | 1999-02-02 | 2001-06-26 | Vysis, Inc. | Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays |
AU3246200A (en) | 1999-02-25 | 2000-09-14 | Boris Bilynsky | Nucleic acid molecules associated with melanoma and thyroid tumors |
US20020039764A1 (en) | 1999-03-12 | 2002-04-04 | Rosen Craig A. | Nucleic, acids, proteins, and antibodies |
US6960439B2 (en) | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
US6692916B2 (en) | 1999-06-28 | 2004-02-17 | Source Precision Medicine, Inc. | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles |
US6326148B1 (en) | 1999-07-12 | 2001-12-04 | The Regents Of The University Of California | Detection of copy number changes in colon cancer |
US6710170B2 (en) | 1999-09-10 | 2004-03-23 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
US6271002B1 (en) | 1999-10-04 | 2001-08-07 | Rosetta Inpharmatics, Inc. | RNA amplification method |
EP1218394A4 (en) | 1999-10-06 | 2004-04-14 | Univ California | Differentially expressed genes associated with her-2/neu overexpression |
EP2228446A1 (en) | 1999-12-01 | 2010-09-15 | Genentech, Inc. | Secreted and transmembrane polypeptieds and nucleic acids encoding the same |
US6750013B2 (en) | 1999-12-02 | 2004-06-15 | Protein Design Labs, Inc. | Methods for detection and diagnosing of breast cancer |
US6248535B1 (en) | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
WO2001051664A2 (en) * | 2000-01-12 | 2001-07-19 | Dana-Farber Cancer Institute, Inc. | Method of detecting and characterizing a neoplasm |
WO2001051661A2 (en) | 2000-01-13 | 2001-07-19 | Amsterdam Support Diagnostics B.V. | A universal nucleic acid amplification system for nucleic acids in a sample |
US6322986B1 (en) | 2000-01-18 | 2001-11-27 | Albany Medical College | Method for colorectal cancer prognosis and treatment selection |
EP1257664A4 (en) | 2000-01-28 | 2006-04-05 | Althea Technologies Inc | Methods for analysis of gene expression |
CA2395398A1 (en) | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
AU4592601A (en) | 2000-03-21 | 2001-10-03 | Millennium Predictive Medicine | Novel genes, compositions, kits, and method for identification, assessment, prevention, and therapy of ovarian cancer |
AU2001251086A1 (en) | 2000-03-31 | 2001-10-15 | Sir Mortimer B. Davis Jewish General Hospital | Microchip arrays of regulatory genes |
WO2002000677A1 (en) | 2000-06-07 | 2002-01-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
WO2002008461A2 (en) | 2000-07-21 | 2002-01-31 | Global Genomics Ab | A METHOD AND AN ALGORITHM FOR mRNA EXPRESSION ANALYSIS |
AU2001277202A1 (en) | 2000-07-26 | 2002-02-05 | Applied Genomics, Inc. | Bstp-ras/rerg protein and related reagents and methods of use thereof |
US7118853B2 (en) | 2000-07-26 | 2006-10-10 | Applied Genomics, Inc. | Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors |
AU2001278011A1 (en) | 2000-07-26 | 2002-02-05 | Applied Genomics, Inc. | Bstp-ecg1 protein and related reagents and methods of use thereof |
US7795232B1 (en) | 2000-08-25 | 2010-09-14 | Genta Incorporated | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
US6378397B1 (en) * | 2000-10-25 | 2002-04-30 | Jenn Jianq Co., Ltd. | Differential gearing device |
US6582919B2 (en) | 2001-06-11 | 2003-06-24 | Response Genetics, Inc. | Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates |
US6602670B2 (en) | 2000-12-01 | 2003-08-05 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 expression |
AU2002255478A1 (en) | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
US7776518B2 (en) | 2001-01-12 | 2010-08-17 | Yale University | Detection of survivin in the biological fluids of cancer patients |
WO2002057787A2 (en) | 2001-01-12 | 2002-07-25 | Yale University | Detection of survivin in the biological fluids of cancer patients |
MXPA03006617A (en) | 2001-01-24 | 2004-12-02 | Protein Design Labs Inc | Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer. |
CN1554025A (en) | 2001-03-12 | 2004-12-08 | Īŵ���ɷ�����˾ | Cell-based detection and differentiation of disease states |
JP4222835B2 (en) * | 2001-03-14 | 2009-02-12 | 株式会社Dnaチップ研究所 | Cancer prediction methods |
US6655515B2 (en) * | 2001-05-24 | 2003-12-02 | Tecumseh Products Company | Modular bi-directional overrunning wheel clutch |
US7514209B2 (en) | 2001-06-18 | 2009-04-07 | Rosetta Inpharmatics Llc | Diagnosis and prognosis of breast cancer patients |
WO2003011897A1 (en) | 2001-07-27 | 2003-02-13 | The Regents Of The University Of California | Modulation of heregulin and her3 interaction |
US6898531B2 (en) * | 2001-09-05 | 2005-05-24 | Perlegen Sciences, Inc. | Algorithms for selection of primer pairs |
WO2003029273A2 (en) | 2001-09-28 | 2003-04-10 | Whitehead Institute For Biomedical Research | Classification of lung carcinomas using gene expression analysis |
US6964850B2 (en) | 2001-11-09 | 2005-11-15 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
US20030198972A1 (en) | 2001-12-21 | 2003-10-23 | Erlander Mark G. | Grading of breast cancer |
EP1492871A2 (en) | 2002-03-28 | 2005-01-05 | QLT Inc. | Cancer associated protein kinases and their uses |
EP1365034A3 (en) | 2002-05-21 | 2004-02-18 | Bayer HealthCare AG | Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia |
JP2006507841A (en) * | 2002-11-14 | 2006-03-09 | ダーマコン, インコーポレイテッド | Functional and ultrafunctional siRNA |
AU2004203749A1 (en) * | 2003-01-06 | 2004-07-22 | Wyeth | Compositions and methods for diagnosing and treating colon cancers |
US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
PT1597391E (en) | 2003-02-20 | 2008-12-19 | Genomic Health Inc | Use of intronic rna to measure gene expression |
WO2004111603A2 (en) | 2003-05-28 | 2004-12-23 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
CA3061769C (en) * | 2003-06-24 | 2021-10-26 | Genomic Health, Inc. | Methods of predicting the likelihood of long-term survival of a human patient with node-negative, estrogen receptor (er) positive, invasive ductal breast cancer without the recurrence of breast cancer |
WO2005008213A2 (en) | 2003-07-10 | 2005-01-27 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
EP1737980A2 (en) | 2004-04-09 | 2007-01-03 | Fondazione IRCCS Istituto Nazionale dei Tumori | Gene expression markers for predicting response to chemotherapy |
DK1815014T3 (en) | 2004-11-05 | 2012-06-18 | Genomic Health Inc | Molecular indicators of breast cancer prognosis and prediction of treatment response |
JP5020088B2 (en) | 2004-11-05 | 2012-09-05 | ジェノミック ヘルス, インコーポレイテッド | Predicting response to chemotherapy using gene expression markers |
CA2620936A1 (en) | 2005-09-01 | 2007-03-08 | Precision Therapeutics, Inc. | Chemo-sensitivity assays using tumor cells exhibiting persistent phenotypic characteristics |
EP1777523A1 (en) | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
WO2007123772A2 (en) | 2006-03-31 | 2007-11-01 | Genomic Health, Inc. | Genes involved in estrogen metabolism |
AU2008289148A1 (en) | 2007-08-16 | 2009-02-26 | Aventis Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
DK2294215T3 (en) | 2008-05-12 | 2013-04-22 | Genomic Health Inc | Tests to predict cancer patients' response to various chemotherapeutic treatment options |
KR101759175B1 (en) | 2009-07-02 | 2017-07-18 | 바스프 에스이 | Co-agglomerated latex polymer dispersions and methods of preparing and using same |
DK2504451T3 (en) | 2009-11-23 | 2019-08-05 | Genomic Health Inc | Methods for predicting the clinical course of cancer |
-
2003
- 2003-05-19 US US10/440,861 patent/US20040231909A1/en not_active Abandoned
-
2004
- 2004-01-14 EP EP10162867A patent/EP2230318A1/en not_active Ceased
- 2004-01-14 WO PCT/US2004/000985 patent/WO2004065583A2/en active Application Filing
- 2004-01-14 ES ES15190640T patent/ES2725892T3/en not_active Expired - Lifetime
- 2004-01-14 DK DK10162868.3T patent/DK2230319T3/en active
- 2004-01-14 DE DE602004027600T patent/DE602004027600D1/en not_active Expired - Lifetime
- 2004-01-14 ES ES10162868.3T patent/ES2561179T3/en not_active Expired - Lifetime
- 2004-01-14 DK DK04702177.9T patent/DK1587957T3/en active
- 2004-01-14 CA CA3013889A patent/CA3013889A1/en not_active Abandoned
- 2004-01-14 CA CA2829477A patent/CA2829477C/en not_active Expired - Lifetime
- 2004-01-14 CA CA2829472A patent/CA2829472C/en not_active Expired - Lifetime
- 2004-01-14 AT AT04702177T patent/ATE470723T1/en active
- 2004-01-14 US US10/758,307 patent/US7569345B2/en active Active
- 2004-01-14 EP EP15190640.1A patent/EP3059322B1/en not_active Expired - Lifetime
- 2004-01-14 AU AU2004205878A patent/AU2004205878B2/en not_active Expired
- 2004-01-14 JP JP2006500964A patent/JP4723472B2/en not_active Expired - Lifetime
- 2004-01-14 CA CA2829476A patent/CA2829476C/en not_active Expired - Lifetime
- 2004-01-14 DK DK15190640.1T patent/DK3059322T3/en active
- 2004-01-14 EP EP04702177A patent/EP1587957B1/en not_active Expired - Lifetime
- 2004-01-14 CA CA2513117A patent/CA2513117C/en not_active Expired - Lifetime
- 2004-01-14 EP EP10162868.3A patent/EP2230319B1/en not_active Expired - Lifetime
- 2004-01-14 ES ES04702177T patent/ES2346967T3/en not_active Expired - Lifetime
-
2009
- 2009-06-04 US US12/478,632 patent/US8034565B2/en active Active
- 2009-11-16 AU AU2009238287A patent/AU2009238287B2/en not_active Expired
-
2011
- 2011-03-17 HK HK11102676.4A patent/HK1148783A1/en not_active IP Right Cessation
- 2011-08-30 US US13/221,549 patent/US8206919B2/en not_active Expired - Lifetime
-
2012
- 2012-05-16 US US13/473,526 patent/US8741605B2/en not_active Expired - Lifetime
-
2014
- 2014-04-21 US US14/257,723 patent/US9944990B2/en active Active
-
2018
- 2018-02-15 US US15/897,617 patent/US11220715B2/en active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6001583A (en) * | 1994-03-07 | 1999-12-14 | New York University Medical Center | Methods for disrupting GRB-7 complexes |
WO2000055173A1 (en) * | 1999-03-12 | 2000-09-21 | Human Genome Sciences, Inc. | Human breast and ovarian cancer associated gene sequences and polypeptides |
WO2000055180A2 (en) * | 1999-03-12 | 2000-09-21 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
WO2001075160A1 (en) * | 2000-03-31 | 2001-10-11 | Vysis, Inc. | Patient stratification for cancer therapy based on genomic dna microarray analysis |
WO2002010436A2 (en) * | 2000-07-28 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Prognostic classification of breast cancer |
WO2002046467A2 (en) * | 2000-12-08 | 2002-06-13 | Ipsogen | Gene expression profiling of primary breast carcinomas using arrays of candidate genes |
WO2002059271A2 (en) * | 2001-01-25 | 2002-08-01 | Gene Logic, Inc. | Gene expression profiles in breast tissue |
WO2003078662A1 (en) * | 2002-03-13 | 2003-09-25 | Genomic Health | Gene expression profiling in biopsied tumor tissues |
Non-Patent Citations (15)
Title |
---|
AHMAD A ET AL: "STROMELYSIN 3: AN INDEPENDENT PROGNOSTIC FACTOR FOR RELAPSE-FREE SURVIVAL IN NODE-POSITIVE BREAST CANCER AND DEMONSTRATION OF NOVEL BREAST CARCINOMA CELL EXPRESSION", AMERICAN JOURNAL OF PATHOLOGY, PHILADELPHIA, PA, US, vol. 152, no. 3, March 1998 (1998-03-01), pages 721 - 728, XP001073488, ISSN: 0002-9440 * |
BORRESEN-DALE A-L: "GENETIC PROFILING OF BREAST CANCER: FROM MOLECULAR PORTRAITS TO CLINICAL UTILITY", INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, WICHTIG EDITORE, MILAN, IT, vol. 18, no. 1, 20 September 2002 (2002-09-20), pages 54 - 56, XP008036675, ISSN: 0393-6155 * |
CHENARD M-P ET AL: "HIGH LEVELS OF STROMELYSIN-3 CORRELATE WITH POOR PROGNOSIS IN PATIENTS WITH BREAST CARCINOMA", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 69, no. 6, 1996, pages 448 - 451, XP008036913, ISSN: 0020-7136 * |
ENGEL G ET AL: "CORRELATION BETWEEN STROMELYSIN-3 MRNA LEVEL AND OUTCOME OF HUMAN BREAST CANCER", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 58, no. 6, 1994, pages 830 - 835, XP008036912, ISSN: 0020-7136 * |
FOROZAN FARAHNAZ ET AL: "Comparative genomic hybridization analysis of 38 breast cancer cell lines: A basis for interpreting complementary DNA microarray data", CANCER RESEARCH, vol. 60, no. 16, 15 August 2000 (2000-08-15), pages 4519 - 4525, XP002304931, ISSN: 0008-5472 * |
GUERIN M ET AL: "STRUCTURE AND EXPRESSION OF C-ERBB-2 AND EGF RECEPTOR GENES IN INFLAMMATORY AND NON-INFLAMMATORY BREAST CANCER: PROGNOSTIC SIGNIFICANCE", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 43, 1989, pages 201 - 208, XP002935671, ISSN: 0020-7136 * |
LEEK R D ET AL: "ASSOCIATION OF MACROPHAGE INFILTRATION WITH ANGIOGENESIS AND PROGNOSIS IN INVASIVE BREAST CARCINOMA", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 56, 15 October 1996 (1996-10-15), pages 4625 - 4629, XP002056968, ISSN: 0008-5472 * |
MURRAY P A ET AL: "The prognostic significance of transforming growth factors in human breast cancer", BRITISH JOURNAL OF CANCER, vol. 67, no. 6, 1993, pages 1408 - 1412, XP008031811, ISSN: 0007-0920 * |
RASCHELLA GIUSEPPE ET AL: "Expression of B-myb in neuroblastoma tumors is a poor prognostic factor independent from MYCN amplification", CANCER RESEARCH, vol. 59, no. 14, 15 July 1999 (1999-07-15), pages 3365 - 3368, XP002304932, ISSN: 0008-5472 * |
SAMUELS-LEV YARDENA ET AL: "ASPP proteins specifically stimulate the apoptotic function of p53", MOLECULAR CELL, vol. 8, no. 4, October 2001 (2001-10-01), pages 781 - 794, XP002202189, ISSN: 1097-2765 * |
SCHORR K ET AL: "BCL-2 GENE FAMILY AND RELATED PROTEINS IN MAMMARY GLAND INVOLUTION AND BREAST CANCER", JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, PLENUM PRESS, NEW YORK, NY,, US, vol. 4, no. 2, April 1999 (1999-04-01), pages 153 - 164, XP000973885, ISSN: 1083-3021 * |
SENS MARY ANN ET AL: "Metallothionein isoform 3 overexpression is associated with breast cancers having a poor prognosis", AMERICAN JOURNAL OF PATHOLOGY, vol. 159, no. 1, July 2001 (2001-07-01), pages 21 - 26, XP002285193, ISSN: 0002-9440 * |
SGROI D C ET AL: "IN VIVO GENE EXPRESSION PROFILE ANALYSIS OF HUMAN BREAST CANCER PROGRESSION", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 59, no. 22, 15 November 1999 (1999-11-15), pages 5656 - 5661, XP000994514, ISSN: 0008-5472 * |
UENO T ET AL: "Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. AUG 2000, vol. 6, no. 8, August 2000 (2000-08-01), pages 3282 - 3289, XP002304930, ISSN: 1078-0432 * |
VEER VAN 'T L J ET AL: "Gene expression profiling predicts clinical outcome of breast cancer", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 415, no. 6871, 31 January 2002 (2002-01-31), pages 530 - 536, XP002259781, ISSN: 0028-0836 * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2004065583A3 (en) | Gene expression markers for breast cancer prognosis | |
WO2005039382A3 (en) | Prediction of likelihood of cancer recurrence | |
WO2008008430A3 (en) | Micro-rna-based methods and compositions for the diagnosis and treatment of colon cancer-related diseases | |
WO2007016548A3 (en) | Micro-rna-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer | |
WO2007081740A3 (en) | Micrornarna-based methods and compositions for the diagnosis and treatment of solid cancers | |
WO2007109236A3 (en) | Microrna fingerprints during human megakaryocytopoiesis | |
WO2004111273A3 (en) | Gene expression markers for response to egfr inhibitor drugs | |
WO2007081720A3 (en) | Microrna-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer | |
HK1108284A1 (en) | Disubstituted pyrazolobenzodiazepines useful as inhibitors for cdk2 and angiogesis, and for the treatment of breast, colon, lung and prostate cancer | |
EP1590433A4 (en) | Diagnosis and prognosis of breast cancer patients | |
WO2006037462A3 (en) | Cancer markers | |
AU2003225093A8 (en) | Soluble mic polypeptides as markers for diagnosis, prognosis and treatment of cancer and autoimmune diseases or conditions | |
AU2003300368A1 (en) | Methods and compositions for the diagnosis, prognosis, and treatment of cancer | |
EP1522594A3 (en) | Methods and kits for investigating cancer | |
EP1742654A4 (en) | Anti-lfl2 antibodies for the diagnosis, prognosis and treatment of cancer | |
WO2005001046A3 (en) | Methods for predicting the course of a malignant disease | |
AU2003217397A1 (en) | Claudins, markers for diagnosis, prognosis and therapy of breast, bone, brain cancer | |
WO2006015191A3 (en) | Multicyclic lonidamine analogs | |
GB0417740D0 (en) | Methods and kit for the prognosis of breast cancer | |
WO2005106043A3 (en) | Breast cancer gene expression biomarkers | |
AU2003218208A1 (en) | Methods for diagnosis and prognosis of cancer | |
WO2005056043A3 (en) | Use of enzymatic inhibitors of h-prune for the prevention and treatment of the metastases of tumours overexpressing h-prune | |
WO2004096021A3 (en) | Global analysis of transposable elements as molecular markers of cancer | |
AU2003298609A1 (en) | Method and cloning vector for preparing multiple-gene diagnostic probes for the assessment of multiple markers for breast cancer prognosis | |
AU2003248889A1 (en) | Multiple gene diagnostic probes and assay kits and method for the assessment of multiple markers for breast cancer prognosis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2513117 Country of ref document: CA Ref document number: 2004205878 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2006500964 Country of ref document: JP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2004702177 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 2004205878 Country of ref document: AU |
|
WWP | Wipo information: published in national office |
Ref document number: 2004702177 Country of ref document: EP |