WO2004060424A3 - Silk-containing stent graft - Google Patents

Silk-containing stent graft Download PDF

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Publication number
WO2004060424A3
WO2004060424A3 PCT/US2003/041494 US0341494W WO2004060424A3 WO 2004060424 A3 WO2004060424 A3 WO 2004060424A3 US 0341494 W US0341494 W US 0341494W WO 2004060424 A3 WO2004060424 A3 WO 2004060424A3
Authority
WO
WIPO (PCT)
Prior art keywords
silk
stent
stent graft
graft
containing stent
Prior art date
Application number
PCT/US2003/041494
Other languages
French (fr)
Other versions
WO2004060424A2 (en
Inventor
David M Gravett
Pierre Signore
Kaiyue Wang
Philip M Toleikis
Dechi Guan
Zengxuan Hu
Arpita Maiti
Original Assignee
Angiotech Int Ag
David M Gravett
Pierre Signore
Kaiyue Wang
Philip M Toleikis
Dechi Guan
Zengxuan Hu
Arpita Maiti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiotech Int Ag, David M Gravett, Pierre Signore, Kaiyue Wang, Philip M Toleikis, Dechi Guan, Zengxuan Hu, Arpita Maiti filed Critical Angiotech Int Ag
Priority to CA002511484A priority Critical patent/CA2511484A1/en
Priority to AU2003300022A priority patent/AU2003300022A1/en
Priority to JP2004565789A priority patent/JP2006516202A/en
Priority to EP03800285A priority patent/EP1581270A2/en
Publication of WO2004060424A2 publication Critical patent/WO2004060424A2/en
Publication of WO2004060424A3 publication Critical patent/WO2004060424A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/89—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2002/065—Y-shaped blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A61F2002/075—Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/258—Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/426—Immunomodulating agents, i.e. cytokines, interleukins, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A61L2300/434—Inhibitors, antagonists of enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow

Abstract

Silk-containing stent grafts are provided comprising an endoluminal stent and a graft, wherein the silk is induces the in vivo adhesion of the stent graft to vessel walls, or, otherwise induces or accelerates an in vivo fibrotic reaction causing said stent graft to adhere to vessel wall. Also provided are methods for making and using such stent grafts.
PCT/US2003/041494 2002-12-30 2003-12-29 Silk-containing stent graft WO2004060424A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002511484A CA2511484A1 (en) 2002-12-30 2003-12-29 Silk-containing stent graft
AU2003300022A AU2003300022A1 (en) 2002-12-30 2003-12-29 Silk-containing stent graft
JP2004565789A JP2006516202A (en) 2002-12-30 2003-12-29 Silk stent graft
EP03800285A EP1581270A2 (en) 2002-12-30 2003-12-29 Silk-containing stent graft

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43746302P 2002-12-30 2002-12-30
US60/437,463 2002-12-30

Publications (2)

Publication Number Publication Date
WO2004060424A2 WO2004060424A2 (en) 2004-07-22
WO2004060424A3 true WO2004060424A3 (en) 2004-12-09

Family

ID=32713187

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/041494 WO2004060424A2 (en) 2002-12-30 2003-12-29 Silk-containing stent graft

Country Status (8)

Country Link
US (2) US20040199241A1 (en)
EP (1) EP1581270A2 (en)
JP (1) JP2006516202A (en)
KR (1) KR20050091040A (en)
CN (1) CN1732022A (en)
AU (1) AU2003300022A1 (en)
CA (1) CA2511484A1 (en)
WO (1) WO2004060424A2 (en)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2178541C (en) 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
US7611533B2 (en) 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US8038708B2 (en) 2001-02-05 2011-10-18 Cook Medical Technologies Llc Implantable device with remodelable material and covering material
US7314484B2 (en) * 2002-07-02 2008-01-01 The Foundry, Inc. Methods and devices for treating aneurysms
EP1613796B1 (en) 2003-04-10 2017-03-22 Tufts University Concentrated aqueous silk fibroin solution and use thereof
FR2861734B1 (en) 2003-04-10 2006-04-14 Corneal Ind CROSSLINKING OF LOW AND HIGH MOLECULAR MASS POLYSACCHARIDES; PREPARATION OF INJECTABLE SINGLE PHASE HYDROGELS; POLYSACCHARIDES AND HYDROGELS OBTAINED
US7396540B2 (en) * 2003-04-25 2008-07-08 Medtronic Vascular, Inc. In situ blood vessel and aneurysm treatment
US20040254629A1 (en) * 2003-04-25 2004-12-16 Brian Fernandes Methods and apparatus for treatment of aneurysmal tissue
US20050037048A1 (en) * 2003-08-11 2005-02-17 Young-Ho Song Medical devices containing antioxidant and therapeutic agent
US20050085894A1 (en) * 2003-10-16 2005-04-21 Kershner James R. High strength and lubricious materials for vascular grafts
AU2004289362A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
JP2007513083A (en) 2003-11-10 2007-05-24 アンジオテック インターナショナル アーゲー Medical implants and fiber inducers
US20050161058A1 (en) * 2004-01-26 2005-07-28 Israel Yerushalmy Spider silk dental floss
WO2005079339A2 (en) * 2004-02-12 2005-09-01 The University Of Akron Improved stent for use in arteries
GB0405045D0 (en) * 2004-03-05 2004-04-07 Spinox Ltd Composite materials
US8003122B2 (en) * 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US8778014B1 (en) * 2004-03-31 2014-07-15 Advanced Cardiovascular Systems, Inc. Coatings for preventing balloon damage to polymer coated stents
AU2011213729B2 (en) * 2004-05-25 2013-01-10 Covidien Lp Flexible vascular occluding device
PT1781264E (en) * 2004-08-04 2013-10-16 Evonik Corp Methods for manufacturing delivery devices and devices thereof
US8980300B2 (en) 2004-08-05 2015-03-17 Advanced Cardiovascular Systems, Inc. Plasticizers for coating compositions
US7413575B2 (en) * 2004-08-30 2008-08-19 Phaneuf Matthew D Nanofibrous biocomposite prosthetic vascular graft
US8968390B2 (en) * 2004-09-27 2015-03-03 Medinol Ltd. Covering for an endoprosthetic device and methods of using for aneurysm treatment
WO2006057859A1 (en) * 2004-11-24 2006-06-01 Therakine Corporation An implant for intraocular drug delivery
US8323348B2 (en) * 2005-02-22 2012-12-04 Taiyen Biotech Co., Ltd. Bone implants
US20060200232A1 (en) * 2005-03-04 2006-09-07 Phaneuf Matthew D Nanofibrous materials as drug, protein, or genetic release vehicles
US8771582B2 (en) 2005-03-04 2014-07-08 BioScurfaces, Inc. Electrospinning process for making a textile suitable for use as a medical article
US10328032B2 (en) 2005-03-04 2019-06-25 Biosurfaces, Inc. Nanofibrous materials as drug, protein, or genetic release vehicles
US20090030454A1 (en) * 2005-04-08 2009-01-29 David Philip Knight Resorbable implantable devices
US8652193B2 (en) 2005-05-09 2014-02-18 Angiomed Gmbh & Co. Medizintechnik Kg Implant delivery device
JP2008540521A (en) * 2005-05-12 2008-11-20 アンジオテック インターナショナル アーゲー Compositions and methods for the treatment of diverticular disease
US20070038285A1 (en) * 2005-05-19 2007-02-15 Biophan Technologies, Inc. Electromagnetic resonant circuit sleeve for implantable medical device
DE102005032691A1 (en) * 2005-07-06 2007-01-18 Biotronik Vi Patent Ag Medical implant (e.g. stent) has a peroxidase covalently attached to its surface
AU2006275881B2 (en) * 2005-07-27 2012-04-12 Cook Medical Technologies Llc Stent/graft device and method for open surgical placement
US20080208312A1 (en) * 2005-09-02 2008-08-28 Medtronic Vascular, Inc. Stent Graft With Strips to Promote Localized Healing
DE102005042455A1 (en) * 2005-09-06 2007-04-12 Medizinische Hochschule Hannover neural implant
KR20080056255A (en) 2005-10-05 2008-06-20 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 Silk proteins
JP2009514627A (en) * 2005-11-10 2009-04-09 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト Reduce restenosis
US20070128242A1 (en) * 2005-12-01 2007-06-07 Zhao Jonathan Z Polymeric compositions for controlled release or delivery of pharmacologically active agents
US8945598B2 (en) * 2005-12-29 2015-02-03 Cordis Corporation Low temperature drying methods for forming drug-containing polymeric compositions
US20070160672A1 (en) * 2006-01-06 2007-07-12 Vipul Bhupendra Dave Methods of making bioabsorbable drug delivery devices comprised of solvent cast films
FR2899581B1 (en) * 2006-04-07 2008-06-27 Guerbet Sa METHOD FOR ATOMIZING IOXILAN
US20070244541A1 (en) * 2006-04-18 2007-10-18 Medtronic Vascular, Inc., A Delaware Corporation Methods and Devices for Contributing to Improved Stent Graft Fixation
US8568764B2 (en) 2006-05-31 2013-10-29 Advanced Cardiovascular Systems, Inc. Methods of forming coating layers for medical devices utilizing flash vaporization
US8246973B2 (en) * 2006-06-21 2012-08-21 Advanced Cardiovascular Systems, Inc. Freeze-thaw method for modifying stent coating
WO2008021831A1 (en) * 2006-08-15 2008-02-21 Medtronic Vascular, Inc. Stent graft with strips to promote localized healing
US8043332B2 (en) * 2006-09-29 2011-10-25 Mattchen Terry M Surgical cable providing visual indication of tension
US8025656B2 (en) * 2006-11-07 2011-09-27 Hologic, Inc. Methods, systems and devices for performing gynecological procedures
EP2097117B1 (en) * 2006-12-11 2013-05-22 Medizinische Hochschule Hannover Implant of cross-linked spider silk threads
US20080181928A1 (en) * 2006-12-22 2008-07-31 Miv Therapeutics, Inc. Coatings for implantable medical devices for liposome delivery
US20080226693A1 (en) * 2007-03-14 2008-09-18 Vipul Bhupendra Dave Apparatus and Method for Making a Polymeric Structure
EP3549551A1 (en) 2007-03-20 2019-10-09 Serica Technologies, Inc. Tendon prosthesis and method of manufacturing the same
BRPI0811784A2 (en) 2007-05-23 2011-05-10 Allergan Inc cross-linked collagen and use thereof
US8133268B2 (en) * 2007-05-30 2012-03-13 Cordis Corporation Stent/fiber structural combinations
US20090004243A1 (en) 2007-06-29 2009-01-01 Pacetti Stephen D Biodegradable triblock copolymers for implantable devices
US20090035351A1 (en) * 2007-07-20 2009-02-05 Medtronic Vascular, Inc. Bioabsorbable Hypotubes for Intravascular Drug Delivery
US8318695B2 (en) 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US9808557B2 (en) 2007-08-10 2017-11-07 Trustees Of Tufts College Tubular silk compositions and methods of use thereof
US8697044B2 (en) * 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
CA2702183A1 (en) * 2007-10-10 2009-04-16 Miv Therapeutics Inc. Lipid coatings for implantable medical devices
JP2011500283A (en) 2007-10-26 2011-01-06 クック クリティカル ケア インコーポレーテッド Vascular conduit and delivery system installed in open surgery
US8642062B2 (en) * 2007-10-31 2014-02-04 Abbott Cardiovascular Systems Inc. Implantable device having a slow dissolving polymer
EP2207424B1 (en) 2007-11-16 2014-06-04 Allergan, Inc. Compositions and methods for treating purpura
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8409601B2 (en) 2008-03-31 2013-04-02 Cordis Corporation Rapamycin coated expandable devices
US8420110B2 (en) * 2008-03-31 2013-04-16 Cordis Corporation Drug coated expandable devices
US8916188B2 (en) 2008-04-18 2014-12-23 Abbott Cardiovascular Systems Inc. Block copolymer comprising at least one polyester block and a poly (ethylene glycol) block
US20090299466A1 (en) * 2008-06-02 2009-12-03 Medtronic Vascular, Inc. Local Delivery of Matrix Metalloproteinase Inhibitors
EP2310063B1 (en) * 2008-07-03 2016-09-28 Vesseltek Biomedical, LLC Controlled and localized release of retinoids to improve neointimal hyperplasia
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
US8642063B2 (en) 2008-08-22 2014-02-04 Cook Medical Technologies Llc Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
ES2829971T3 (en) 2008-09-02 2021-06-02 Tautona Group Lp Hyaluronic acid threads and / or derivatives thereof, methods to manufacture them and uses thereof
KR100983348B1 (en) * 2008-09-19 2010-09-20 정환훈 Metalic stent for ureter
BRPI0920453A2 (en) * 2008-10-09 2015-12-22 Tufts College silk film, fabric engineering construction, methods for preparing a silk film, for covering a surface of a substrate with a silk composition, and for embedding at least one active agent in a silk film, and, film-coated substrate. sedal film
WO2010057142A2 (en) * 2008-11-17 2010-05-20 Trustees Of Tufts College Surface modification of silk fibroin matrices with poly(ethylene glycol) useful as anti adhesion barriers and anti thrombotic materials
EP2405827B1 (en) * 2009-03-10 2020-05-13 The Johns Hopkins University Biological tissue connection and repair devices
US20100274276A1 (en) * 2009-04-22 2010-10-28 Ricky Chow Aneurysm treatment system, device and method
JP5980679B2 (en) 2009-08-26 2016-08-31 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション Process for producing silk dope
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
EP2544652A2 (en) * 2010-03-12 2013-01-16 Allergan Industrie SAS A fluid composition comprising a hyaluronan polymer and mannitol for improving skin condition.
DK2550027T4 (en) 2010-03-22 2019-05-13 Allergan Inc CROSS-BAND POLYSACCHARID AND PROTEIN POLYSACCHARID HYDROCHLORIC PRODUCTS
US8945156B2 (en) 2010-05-19 2015-02-03 University Of Utah Research Foundation Tissue fixation
US8858577B2 (en) 2010-05-19 2014-10-14 University Of Utah Research Foundation Tissue stabilization system
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
CA2809372A1 (en) 2010-08-30 2012-03-08 President And Fellows Of Harvard College A high strength chitin composite material and method of making
US8852214B2 (en) 2011-02-04 2014-10-07 University Of Utah Research Foundation System for tissue fixation to bone
JP2012171124A (en) * 2011-02-18 2012-09-10 Sekisui Chem Co Ltd Pipe making member and method of regenerating existing pipe
JP5062867B2 (en) * 2011-02-18 2012-10-31 福井経編興業株式会社 Double raschel knitted fabric pipe for artificial blood vessel and its manufacturing method
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
EP2714002B1 (en) 2011-06-03 2019-04-03 Allergan, Inc. Dermal filler compositions including antioxidants
GB201113856D0 (en) * 2011-08-11 2011-09-28 Oxford Biomaterials Ltd Medical device
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
KR101330397B1 (en) * 2011-11-01 2013-11-15 재단법인 아산사회복지재단 A device for blood vessel anastomosis using the self-expandable material or structure and a method for blood vessel anastomosis using the same
RU2014124139A (en) 2011-11-16 2015-12-27 Коммонвелт Сайентифик Энд Индастриал Рисерч Организейшн COLLAGEN-LIKE SILK GENES
AU2013239320B2 (en) 2012-03-26 2018-11-01 Commonwealth Scientific And Industrial Research Organisation Silk polypeptides
US11944531B2 (en) 2012-07-30 2024-04-02 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US9427309B2 (en) 2012-07-30 2016-08-30 Conextions, Inc. Soft tissue repair devices, systems, and methods
US10219804B2 (en) 2012-07-30 2019-03-05 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11957334B2 (en) 2012-07-30 2024-04-16 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11253252B2 (en) 2012-07-30 2022-02-22 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US10835241B2 (en) 2012-07-30 2020-11-17 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US10390935B2 (en) 2012-07-30 2019-08-27 Conextions, Inc. Soft tissue to bone repair devices, systems, and methods
CN103007345B (en) * 2012-12-20 2015-01-07 深圳清华大学研究院 Antibacterial biological activity stent and preparation method thereof
US9949692B2 (en) 2012-12-21 2018-04-24 Canary Medical Inc. Stent graft monitoring assembly and method of use thereof
US10154918B2 (en) 2012-12-28 2018-12-18 Cook Medical Technologies Llc Endoluminal prosthesis with fiber matrix
WO2015117888A1 (en) * 2014-02-04 2015-08-13 Amsilk Gmbh Coated silk films, methods for the production thereof and uses thereof
US11583384B2 (en) 2014-03-12 2023-02-21 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
WO2015138760A1 (en) 2014-03-12 2015-09-17 Conextions, Inc. Soft tissue repair devices, systems, and methods
WO2015200718A1 (en) 2014-06-25 2015-12-30 Hunter William L Devices, systems and methods for using and monitoring tubes in body passageways
CN104127916B (en) * 2014-07-15 2015-11-18 东南大学 Have antibacterial and promote osteogenesis function absorbable orthopedic instrument material and preparation method
EP3200838B1 (en) 2014-09-30 2019-09-18 Allergan Industrie, SAS Stable hydrogel compositions including additives
CN107405277B (en) * 2014-12-02 2021-08-10 丝绸医疗公司 Silk performance garments and products and methods of making same
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
WO2016134181A1 (en) * 2015-02-18 2016-08-25 The George Washington University Photon enhanced biological scaffolds
US10232082B2 (en) * 2015-06-29 2019-03-19 480 Biomedical, Inc. Implantable scaffolds for treatment of sinusitis
US11512425B2 (en) 2015-07-14 2022-11-29 Evolved By Nature, Inc. Silk performance apparel and products and methods of preparing the same
JP6200465B2 (en) * 2015-07-23 2017-09-20 日本ライフライン株式会社 Stent graft
US10512533B1 (en) 2016-02-23 2019-12-24 W. L. Gore & Associates, Inc. Branched graft assembly method in vivo
CN106310380B (en) * 2016-08-19 2019-09-17 苏州大学 A kind of nanofiber Silk fibroin gel and preparation method thereof
US11696822B2 (en) 2016-09-28 2023-07-11 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
CN107913436A (en) * 2016-10-09 2018-04-17 刘英芹 Act on the bone and soft tissue synchronizing regeneration derivant of disability tissue in situ
EP3315147A1 (en) * 2016-10-28 2018-05-02 Bioengineering Laboratories S.r.l. Hybrid scaffold suitable for regenerating tissues and production process
US11439728B2 (en) * 2017-03-23 2022-09-13 Council Of Scientific & Industrial Research Process for coating a biomedical implant with a biocompatible polymer and a biomedical implant therefrom
US10375120B2 (en) 2017-05-12 2019-08-06 Sap Se Positionally-encoded string representations, including their use in machine learning and in security applications
US11390988B2 (en) 2017-09-27 2022-07-19 Evolved By Nature, Inc. Silk coated fabrics and products and methods of preparing the same
US11547397B2 (en) 2017-12-20 2023-01-10 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
CA3091800A1 (en) 2018-02-20 2019-08-29 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
CN109289089B (en) * 2018-10-15 2021-12-28 福建师范大学 Preparation method of temperature-controlled intelligent drug release system based on titanium dioxide nanotube array
CN109289049B (en) * 2018-10-15 2021-04-02 福建师范大学 Preparation method of near-infrared light-controlled intelligent drug release system based on titanium dioxide nanotube array
CN111358955B (en) * 2020-04-01 2023-05-02 重庆理工大学 Inflammation targeted bindarit nanoparticle for treating lipid metabolism diseases, preparation method and application thereof
CN115120618B (en) * 2021-03-23 2024-01-26 安徽盛美诺生物技术有限公司 Cartilage extract with immune response improving effect, preparation method and application thereof
CN113520685A (en) * 2021-08-03 2021-10-22 上海微创医疗器械（集团）有限公司 Stent for blood vessels
WO2023059810A1 (en) * 2021-10-06 2023-04-13 University Of Connecticut Stents and methods of use

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0666066A1 (en) * 1994-02-08 1995-08-09 Ethicon, Inc. Bi-directional crimped graft
EP0997115A2 (en) * 1994-04-01 2000-05-03 Prograft Medical, Inc. Self-expandable stent and stent-graft and method of using them
WO2000040278A1 (en) * 1998-12-31 2000-07-13 Angiotech Pharmaceuticals, Inc. Stent grafts with bioactive coatings
WO2000050016A2 (en) * 1999-02-23 2000-08-31 Angiotech Pharmaceuticals, Inc. Compositions and methods for improving integrity of compromised body passageways and cavities
US20010053931A1 (en) * 1999-11-24 2001-12-20 Salvatore J. Abbruzzese Thin-layered, endovascular silk-covered stent device and method of manufacture thereof
US20020065546A1 (en) * 1998-12-31 2002-05-30 Machan Lindsay S. Stent grafts with bioactive coatings
US20020107330A1 (en) * 2000-12-12 2002-08-08 Leonard Pinchuk Drug delivery compositions and medical devices containing block copolymer

Family Cites Families (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3038339B2 (en) * 1988-05-02 2000-05-08 ザイナクシス・テクノロジーズ・インコーポレーテッド Compounds that bind bioaffecting substances to the surface membrane of bioparticles
US4906460A (en) * 1988-08-05 1990-03-06 Sorenco Additive for hair treatment compositions
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5989894A (en) * 1990-04-20 1999-11-23 University Of Wyoming Isolated DNA coding for spider silk protein, a replicable vector and a transformed cell containing the DNA
US5360443A (en) * 1990-06-11 1994-11-01 Barone Hector D Aortic graft for repairing an abdominal aortic aneurysm
US5578071A (en) * 1990-06-11 1996-11-26 Parodi; Juan C. Aortic graft
US6515009B1 (en) * 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5683448A (en) * 1992-02-21 1997-11-04 Boston Scientific Technology, Inc. Intraluminal stent and graft
US5405377A (en) * 1992-02-21 1995-04-11 Endotech Ltd. Intraluminal stent
US5383928A (en) * 1992-06-10 1995-01-24 Emory University Stent sheath for local drug delivery
US5342387A (en) * 1992-06-18 1994-08-30 American Biomed, Inc. Artificial support for a blood vessel
BE1006440A3 (en) * 1992-12-21 1994-08-30 Dereume Jean Pierre Georges Em Luminal endoprosthesis AND METHOD OF PREPARATION.
US5981568A (en) * 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US6096331A (en) * 1993-02-22 2000-08-01 Vivorx Pharmaceuticals, Inc. Methods and compositions useful for administration of chemotherapeutic agents
DE69433299T2 (en) * 1993-06-15 2004-09-09 E.I. Du Pont De Nemours And Co., Wilmington RECOMBINANT SPIDER SILK ANALOG
US5716981A (en) * 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use
DE69434598T3 (en) * 1993-07-29 2010-07-29 The United States Of America Represented By The Secretary, Department Of Health And Human Services Use of paclitaxel and its derivatives for the manufacture of a medicament for the treatment of restenosis
CA2169549C (en) * 1993-08-18 2000-07-11 James D. Lewis A tubular intraluminal graft
US5735892A (en) * 1993-08-18 1998-04-07 W. L. Gore & Associates, Inc. Intraluminal stent graft
US5855598A (en) * 1993-10-21 1999-01-05 Corvita Corporation Expandable supportive branched endoluminal grafts
US5723004A (en) * 1993-10-21 1998-03-03 Corvita Corporation Expandable supportive endoluminal grafts
US5632772A (en) * 1993-10-21 1997-05-27 Corvita Corporation Expandable supportive branched endoluminal grafts
US5639278A (en) * 1993-10-21 1997-06-17 Corvita Corporation Expandable supportive bifurcated endoluminal grafts
US5609627A (en) * 1994-02-09 1997-03-11 Boston Scientific Technology, Inc. Method for delivering a bifurcated endoluminal prosthesis
US5415664A (en) * 1994-03-30 1995-05-16 Corvita Corporation Method and apparatus for introducing a stent or a stent-graft
US6001123A (en) * 1994-04-01 1999-12-14 Gore Enterprise Holdings Inc. Folding self-expandable intravascular stent-graft
US6140452A (en) * 1994-05-06 2000-10-31 Advanced Bio Surfaces, Inc. Biomaterial for in situ tissue repair
EP0689805B1 (en) * 1994-06-27 2003-05-28 Corvita Corporation Bistable luminal graft endoprostheses
US5626862A (en) * 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
US6015429A (en) * 1994-09-08 2000-01-18 Gore Enterprise Holdings, Inc. Procedures for introducing stents and stent-grafts
US5643580A (en) * 1994-10-17 1997-07-01 Surface Genesis, Inc. Biocompatible coating, medical device using the same and methods
BE1009278A3 (en) * 1995-04-12 1997-01-07 Corvita Europ Guardian self-expandable medical device introduced in cavite body, and medical device with a stake as.
JP3133642B2 (en) * 1995-05-19 2001-02-13 花王株式会社 Hair cosmetics
DE69634013T2 (en) * 1995-05-26 2005-12-15 SurModics, Inc., Eden Prairie PROCESS AND IMPLANTABLE OBJECT FOR PROMOTING ENDOTHELIALIZATION
US5700269A (en) * 1995-06-06 1997-12-23 Corvita Corporation Endoluminal prosthesis deployment device for use with prostheses of variable length and having retraction ability
US5820595A (en) * 1995-06-07 1998-10-13 Parodi; Juan C. Adjustable inflatable catheter and method for adjusting the relative position of multiple inflatable portions of a catheter within a body passageway
US5725568A (en) * 1995-06-27 1998-03-10 Scimed Life Systems, Inc. Method and device for recanalizing and grafting arteries
US5749918A (en) * 1995-07-20 1998-05-12 Endotex Interventional Systems, Inc. Intraluminal graft and method for inserting the same
US5607475A (en) * 1995-08-22 1997-03-04 Medtronic, Inc. Biocompatible medical article and method
US5591195A (en) * 1995-10-30 1997-01-07 Taheri; Syde Apparatus and method for engrafting a blood vessel
US5628788A (en) * 1995-11-07 1997-05-13 Corvita Corporation Self-expanding endoluminal stent-graft
US5782810A (en) * 1995-11-22 1998-07-21 O'donnell; Miles C. Multipart radiopaque and/or magnetically detectable tube catheter and method of fabrication thereof
US6168622B1 (en) * 1996-01-24 2001-01-02 Microvena Corporation Method and apparatus for occluding aneurysms
US5948427A (en) * 1996-04-25 1999-09-07 Point Medical Corporation Microparticulate surgical adhesive
US5709701A (en) * 1996-05-30 1998-01-20 Parodi; Juan C. Apparatus for implanting a prothesis within a body passageway
US5916585A (en) * 1996-06-03 1999-06-29 Gore Enterprise Holdings, Inc. Materials and method for the immobilization of bioactive species onto biodegradable polymers
US5877263A (en) * 1996-11-25 1999-03-02 Meadox Medicals, Inc. Process for preparing polymer coatings grafted with polyethylene oxide chains containing covalently bonded bio-active agents
US5980972A (en) * 1996-12-20 1999-11-09 Schneider (Usa) Inc Method of applying drug-release coatings
US6015431A (en) * 1996-12-23 2000-01-18 Prograft Medical, Inc. Endolumenal stent-graft with leak-resistant seal
US5824054A (en) * 1997-03-18 1998-10-20 Endotex Interventional Systems, Inc. Coiled sheet graft stent and methods of making and use
US6273913B1 (en) * 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
DE19720115C2 (en) * 1997-05-14 1999-05-20 Jomed Implantate Gmbh Stent graft
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US6235051B1 (en) * 1997-12-16 2001-05-22 Timothy P. Murphy Method of stent-graft system delivery
US5994099A (en) * 1997-12-31 1999-11-30 The University Of Wyoming Extremely elastic spider silk protein and DNA coding therefor
US6181960B1 (en) * 1998-01-15 2001-01-30 University Of Virginia Patent Foundation Biopsy marker device
ES2252926T3 (en) * 1998-01-26 2006-05-16 Anson Medical Limited REINFORCED GRAFT.
US6206916B1 (en) * 1998-04-15 2001-03-27 Joseph G. Furst Coated intraluminal graft
CN1379681A (en) * 1998-04-17 2002-11-13 安乔格尼克斯公司 therapeutic angiogenic factors and methods for their use
US6113629A (en) * 1998-05-01 2000-09-05 Micrus Corporation Hydrogel for the therapeutic treatment of aneurysms
US6296603B1 (en) * 1998-05-26 2001-10-02 Isostent, Inc. Radioactive intraluminal endovascular prosthesis and method for the treatment of aneurysms
US6605294B2 (en) * 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US6156064A (en) * 1998-08-14 2000-12-05 Schneider (Usa) Inc Stent-graft-membrane and method of making the same
US6335029B1 (en) * 1998-08-28 2002-01-01 Scimed Life Systems, Inc. Polymeric coatings for controlled delivery of active agents
EP1726271B1 (en) * 1998-09-30 2012-07-25 Bard Peripheral Vascular, Inc. Selective adherence of stentgraft coverings, mandrel and method of making stent-graft device
US6176849B1 (en) * 1999-05-21 2001-01-23 Scimed Life Systems, Inc. Hydrophilic lubricity coating for medical devices comprising a hydrophobic top coat
JP3362778B2 (en) * 1999-06-03 2003-01-07 独立行政法人農業生物資源研究所 Method for producing ultrafine crystalline silk powder
US6592566B2 (en) * 2000-02-03 2003-07-15 Arizona Board Of Regents Method for forming an endovascular occlusion
US6719778B1 (en) * 2000-03-24 2004-04-13 Endovascular Technologies, Inc. Methods for treatment of aneurysms
US6254632B1 (en) * 2000-09-28 2001-07-03 Advanced Cardiovascular Systems, Inc. Implantable medical device having protruding surface structures for drug delivery and cover attachment
US6468660B2 (en) * 2000-12-29 2002-10-22 St. Jude Medical, Inc. Biocompatible adhesives
WO2002089865A2 (en) * 2001-05-04 2002-11-14 Concentric Medical Coated combination vaso-occlusive device
US7122048B2 (en) * 2002-05-03 2006-10-17 Scimed Life Systems, Inc. Hypotube endoluminal device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0666066A1 (en) * 1994-02-08 1995-08-09 Ethicon, Inc. Bi-directional crimped graft
EP0997115A2 (en) * 1994-04-01 2000-05-03 Prograft Medical, Inc. Self-expandable stent and stent-graft and method of using them
WO2000040278A1 (en) * 1998-12-31 2000-07-13 Angiotech Pharmaceuticals, Inc. Stent grafts with bioactive coatings
US20020065546A1 (en) * 1998-12-31 2002-05-30 Machan Lindsay S. Stent grafts with bioactive coatings
WO2000050016A2 (en) * 1999-02-23 2000-08-31 Angiotech Pharmaceuticals, Inc. Compositions and methods for improving integrity of compromised body passageways and cavities
US20010053931A1 (en) * 1999-11-24 2001-12-20 Salvatore J. Abbruzzese Thin-layered, endovascular silk-covered stent device and method of manufacture thereof
US20020107330A1 (en) * 2000-12-12 2002-08-08 Leonard Pinchuk Drug delivery compositions and medical devices containing block copolymer

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