WO2004054501A3 - Methods of usig and compositions comprising (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide - Google Patents
Methods of usig and compositions comprising (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide Download PDFInfo
- Publication number
- WO2004054501A3 WO2004054501A3 PCT/US2003/036741 US0336741W WO2004054501A3 WO 2004054501 A3 WO2004054501 A3 WO 2004054501A3 US 0336741 W US0336741 W US 0336741W WO 2004054501 A3 WO2004054501 A3 WO 2004054501A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- isoindol
- propionamide
- dimethoxy
- dihydro
- oxo
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004560320A JP2006515844A (en) | 2002-11-18 | 2003-11-17 | Method of using (-)-3- (3,4-dimethoxy-phenyl) -3- (1-oxo-1,3-dihydro-isoindol-2-yl) -propionamide and composition comprising the same |
AU2003294312A AU2003294312A1 (en) | 2002-11-18 | 2003-11-17 | Methods of usig and compositions comprising (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide |
EP03789795A EP1569599A2 (en) | 2002-11-18 | 2003-11-17 | Methods of usig and compositions comprising (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide |
CA002506442A CA2506442A1 (en) | 2002-11-18 | 2003-11-17 | Methods of using and compositions comprising (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide |
MXPA05005161A MXPA05005161A (en) | 2002-11-18 | 2003-11-17 | Methods of usig and compositions comprising (-)-3- (3, 4- dimethoxy -phenyl)-3 -(1-oxo-1, 3-dihydro- isoindol- 2-yl)- propionamide. |
NZ540546A NZ540546A (en) | 2002-11-18 | 2003-11-17 | Methods of using and compositions comprising (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide |
BR0316256-7A BR0316256A (en) | 2002-11-18 | 2003-11-17 | Methods of inhibiting tnf-alpha production and pde4 activity, treating or preventing a disease or disorder, controlling camp levels in a cell and producing a compound, pharmaceutical composition and compound |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42738002P | 2002-11-18 | 2002-11-18 | |
US60/427,380 | 2002-11-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004054501A2 WO2004054501A2 (en) | 2004-07-01 |
WO2004054501A3 true WO2004054501A3 (en) | 2004-08-26 |
Family
ID=32595070
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/036741 WO2004054501A2 (en) | 2002-11-18 | 2003-11-17 | Methods of usig and compositions comprising (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide |
Country Status (13)
Country | Link |
---|---|
US (1) | US20040167199A1 (en) |
EP (1) | EP1569599A2 (en) |
JP (1) | JP2006515844A (en) |
KR (1) | KR20050086715A (en) |
CN (1) | CN1738614A (en) |
AU (1) | AU2003294312A1 (en) |
BR (1) | BR0316256A (en) |
CA (1) | CA2506442A1 (en) |
MX (1) | MXPA05005161A (en) |
NZ (1) | NZ540546A (en) |
TW (1) | TW200415143A (en) |
WO (1) | WO2004054501A2 (en) |
ZA (1) | ZA200503926B (en) |
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- 2003-11-17 BR BR0316256-7A patent/BR0316256A/en not_active Withdrawn
- 2003-11-17 NZ NZ540546A patent/NZ540546A/en unknown
- 2003-11-17 EP EP03789795A patent/EP1569599A2/en not_active Withdrawn
- 2003-11-17 US US10/715,184 patent/US20040167199A1/en not_active Abandoned
- 2003-11-17 AU AU2003294312A patent/AU2003294312A1/en not_active Abandoned
- 2003-11-17 JP JP2004560320A patent/JP2006515844A/en active Pending
- 2003-11-17 CN CNA2003801089012A patent/CN1738614A/en active Pending
- 2003-11-17 KR KR1020057008909A patent/KR20050086715A/en not_active Application Discontinuation
- 2003-11-17 MX MXPA05005161A patent/MXPA05005161A/en unknown
- 2003-11-17 WO PCT/US2003/036741 patent/WO2004054501A2/en active Application Filing
- 2003-11-17 CA CA002506442A patent/CA2506442A1/en not_active Abandoned
- 2003-11-18 TW TW092132307A patent/TW200415143A/en unknown
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2005
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EP1569599A2 (en) | 2005-09-07 |
NZ540546A (en) | 2008-03-28 |
ZA200503926B (en) | 2006-08-30 |
TW200415143A (en) | 2004-08-16 |
AU2003294312A1 (en) | 2004-07-09 |
CN1738614A (en) | 2006-02-22 |
CA2506442A1 (en) | 2004-07-01 |
JP2006515844A (en) | 2006-06-08 |
WO2004054501A2 (en) | 2004-07-01 |
MXPA05005161A (en) | 2005-07-22 |
KR20050086715A (en) | 2005-08-30 |
US20040167199A1 (en) | 2004-08-26 |
BR0316256A (en) | 2005-10-04 |
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