WO2004036765A3 - Neural stimulation system and method responsive to collateral neural activity - Google Patents

Neural stimulation system and method responsive to collateral neural activity Download PDF

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Publication number
WO2004036765A3
WO2004036765A3 PCT/US2003/032599 US0332599W WO2004036765A3 WO 2004036765 A3 WO2004036765 A3 WO 2004036765A3 US 0332599 W US0332599 W US 0332599W WO 2004036765 A3 WO2004036765 A3 WO 2004036765A3
Authority
WO
WIPO (PCT)
Prior art keywords
neural
stimulation
collateral
activity
neural activity
Prior art date
Application number
PCT/US2003/032599
Other languages
French (fr)
Other versions
WO2004036765A2 (en
Inventor
Bradford Evan Gliner
Original Assignee
Northstar Neuroscience Inc
Bradford Evan Gliner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northstar Neuroscience Inc, Bradford Evan Gliner filed Critical Northstar Neuroscience Inc
Priority to EP03786531A priority Critical patent/EP1554011A4/en
Priority to AU2003295349A priority patent/AU2003295349B2/en
Priority to CA002502557A priority patent/CA2502557A1/en
Publication of WO2004036765A2 publication Critical patent/WO2004036765A2/en
Publication of WO2004036765A3 publication Critical patent/WO2004036765A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36182—Direction of the electrical field, e.g. with sleeve around stimulating electrode
    • A61N1/36185—Selection of the electrode configuration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A61B5/377—Electroencephalography [EEG] using evoked responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4094—Diagnosing or monitoring seizure diseases, e.g. epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0531—Brain cortex electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1104—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0553—Paddle shaped electrodes, e.g. for laminotomy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36017—External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/3756—Casings with electrodes thereon, e.g. leadless stimulators

Abstract

A neural stimulation system responsive to collateral neural activity that may arise in association with a neural stimulation procedure includes a stimulation interface configured to deliver stimulation signals to a target neural population, a monitoring interface positioned to receive signals corresponding to a neural activity within the target neural population, a stimulus unit coupled to deliver stimulation singals to the stimulation interface, and a sensing unit coupled to the monitoring device and the stimulus unit. The neural stimulation procedure may be directed toward rehabilitating, restoring, and/or enhancing one or more neural functions by facilitating and/or effectuating a neuroplastic change or reorganization; and/or affecting a neurological condition that exists on a continuous or essentially continuous basis absent the stimulation procedure. The sensing unit determines whether evidence of an collateral neural activity exists, whereupon the stimulus unit attempts to abate the collateral neural activity.
PCT/US2003/032599 2002-10-15 2003-10-15 Neural stimulation system and method responsive to collateral neural activity WO2004036765A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP03786531A EP1554011A4 (en) 2002-10-15 2003-10-15 Neural stimulation system and method responsive to collateral neural activity
AU2003295349A AU2003295349B2 (en) 2002-10-15 2003-10-15 Neural stimulation system and method responsive to collateral neural activity
CA002502557A CA2502557A1 (en) 2002-10-15 2003-10-15 Neural stimulation system and method responsive to collateral neural activity

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/271,394 2002-10-15
US10/271,394 US7831305B2 (en) 2001-10-15 2002-10-15 Neural stimulation system and method responsive to collateral neural activity

Publications (2)

Publication Number Publication Date
WO2004036765A2 WO2004036765A2 (en) 2004-04-29
WO2004036765A3 true WO2004036765A3 (en) 2005-03-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/032599 WO2004036765A2 (en) 2002-10-15 2003-10-15 Neural stimulation system and method responsive to collateral neural activity

Country Status (5)

Country Link
US (3) US7831305B2 (en)
EP (1) EP1554011A4 (en)
AU (1) AU2003295349B2 (en)
CA (1) CA2502557A1 (en)
WO (1) WO2004036765A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11848090B2 (en) 2019-05-24 2023-12-19 Axonics, Inc. Trainer for a neurostimulator programmer and associated methods of use with a neurostimulation system

Families Citing this family (169)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050021118A1 (en) * 2000-07-13 2005-01-27 Chris Genau Apparatuses and systems for applying electrical stimulation to a patient
US7305268B2 (en) * 2000-07-13 2007-12-04 Northstar Neurscience, Inc. Systems and methods for automatically optimizing stimulus parameters and electrode configurations for neuro-stimulators
US7024247B2 (en) 2001-10-15 2006-04-04 Northstar Neuroscience, Inc. Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures
US7756584B2 (en) * 2000-07-13 2010-07-13 Advanced Neuromodulation Systems, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7672730B2 (en) * 2001-03-08 2010-03-02 Advanced Neuromodulation Systems, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7010351B2 (en) * 2000-07-13 2006-03-07 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US20030125786A1 (en) * 2000-07-13 2003-07-03 Gliner Bradford Evan Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7146217B2 (en) * 2000-07-13 2006-12-05 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a change in a neural-function of a patient
US7831305B2 (en) 2001-10-15 2010-11-09 Advanced Neuromodulation Systems, Inc. Neural stimulation system and method responsive to collateral neural activity
US7299096B2 (en) * 2001-03-08 2007-11-20 Northstar Neuroscience, Inc. System and method for treating Parkinson's Disease and other movement disorders
WO2003026738A1 (en) * 2001-09-28 2003-04-03 Northstar Neuroscience, Inc. Methods and apparatus for electrically stimulating cells implanted in the nervous system
US7221981B2 (en) * 2002-03-28 2007-05-22 Northstar Neuroscience, Inc. Electrode geometries for efficient neural stimulation
US7236830B2 (en) 2002-12-10 2007-06-26 Northstar Neuroscience, Inc. Systems and methods for enhancing or optimizing neural stimulation therapy for treating symptoms of Parkinson's disease and/or other movement disorders
US20050075680A1 (en) 2003-04-18 2005-04-07 Lowry David Warren Methods and systems for intracranial neurostimulation and/or sensing
US7302298B2 (en) * 2002-11-27 2007-11-27 Northstar Neuroscience, Inc Methods and systems employing intracranial electrodes for neurostimulation and/or electroencephalography
US8118722B2 (en) * 2003-03-07 2012-02-21 Neuronetics, Inc. Reducing discomfort caused by electrical stimulation
US7153256B2 (en) 2003-03-07 2006-12-26 Neuronetics, Inc. Reducing discomfort caused by electrical stimulation
US7107104B2 (en) * 2003-05-30 2006-09-12 Medtronic, Inc. Implantable cortical neural lead and method
US7684866B2 (en) * 2003-08-01 2010-03-23 Advanced Neuromodulation Systems, Inc. Apparatus and methods for applying neural stimulation to a patient
US7617002B2 (en) * 2003-09-15 2009-11-10 Medtronic, Inc. Selection of neurostimulator parameter configurations using decision trees
US7239926B2 (en) 2003-09-15 2007-07-03 Medtronic, Inc. Selection of neurostimulator parameter configurations using genetic algorithms
US7104947B2 (en) 2003-11-17 2006-09-12 Neuronetics, Inc. Determining stimulation levels for transcranial magnetic stimulation
US9050469B1 (en) 2003-11-26 2015-06-09 Flint Hills Scientific, Llc Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals
US7647097B2 (en) * 2003-12-29 2010-01-12 Braingate Co., Llc Transcutaneous implant
US7422555B2 (en) * 2003-12-30 2008-09-09 Jacob Zabara Systems and methods for therapeutically treating neuro-psychiatric disorders and other illnesses
US7651459B2 (en) * 2004-01-06 2010-01-26 Neuronetics, Inc. Method and apparatus for coil positioning for TMS studies
WO2005087314A1 (en) * 2004-03-11 2005-09-22 Advanced Neuromodulation Systems, Inc. Brain stimulation system and method
US20050203366A1 (en) * 2004-03-12 2005-09-15 Donoghue John P. Neurological event monitoring and therapy systems and related methods
US8177702B2 (en) 2004-04-15 2012-05-15 Neuronetics, Inc. Method and apparatus for determining the proximity of a TMS coil to a subject's head
NL1026137C2 (en) * 2004-05-07 2005-11-08 Vanderlande Ind Nederland Device for sorting products.
US7601115B2 (en) * 2004-05-24 2009-10-13 Neuronetics, Inc. Seizure therapy method and apparatus
EP1786510A4 (en) * 2004-07-15 2009-12-02 Northstar Neuroscience Inc Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy
US7711432B2 (en) 2004-07-26 2010-05-04 Advanced Neuromodulation Systems, Inc. Stimulation system and method for treating a neurological disorder
WO2006014896A1 (en) * 2004-07-26 2006-02-09 Advanced Neuromodulation Systems, Inc. Stimulation system and method treating a neurological disorder
US20060058627A1 (en) * 2004-08-13 2006-03-16 Flaherty J C Biological interface systems with wireless connection and related methods
EP1827207A2 (en) * 2004-10-04 2007-09-05 Cyberkinetics Neurotechnology Systems, Inc. Biological interface system
US8175705B2 (en) * 2004-10-12 2012-05-08 Cardiac Pacemakers, Inc. System and method for sustained baroreflex stimulation
US7857746B2 (en) * 2004-10-29 2010-12-28 Nueronetics, Inc. System and method to reduce discomfort using nerve stimulation
US20060106430A1 (en) * 2004-11-12 2006-05-18 Brad Fowler Electrode configurations for reducing invasiveness and/or enhancing neural stimulation efficacy, and associated methods
US7565200B2 (en) 2004-11-12 2009-07-21 Advanced Neuromodulation Systems, Inc. Systems and methods for selecting stimulation sites and applying treatment, including treatment of symptoms of Parkinson's disease, other movement disorders, and/or drug side effects
US7341562B2 (en) * 2004-12-15 2008-03-11 Neuropace, Inc. Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders
US7819812B2 (en) * 2004-12-15 2010-10-26 Neuropace, Inc. Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders
US20070032738A1 (en) 2005-01-06 2007-02-08 Flaherty J C Adaptive patient training routine for biological interface system
US8095209B2 (en) * 2005-01-06 2012-01-10 Braingate Co., Llc Biological interface system with gated control signal
US7901368B2 (en) * 2005-01-06 2011-03-08 Braingate Co., Llc Neurally controlled patient ambulation system
US8812096B2 (en) * 2005-01-10 2014-08-19 Braingate Co., Llc Biological interface system with patient training apparatus
US20060189899A1 (en) * 2005-01-10 2006-08-24 Flaherty J Christopher Joint movement apparatus
US7881780B2 (en) * 2005-01-18 2011-02-01 Braingate Co., Llc Biological interface system with thresholded configuration
US8088058B2 (en) * 2005-01-20 2012-01-03 Neuronetics, Inc. Articulating arm
US8565867B2 (en) 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US20070060954A1 (en) * 2005-02-25 2007-03-15 Tracy Cameron Method of using spinal cord stimulation to treat neurological disorders or conditions
US20060199159A1 (en) * 2005-03-01 2006-09-07 Neuronetics, Inc. Head phantom for simulating the patient response to magnetic stimulation
US7542800B2 (en) 2005-04-05 2009-06-02 Cardiac Pacemakers, Inc. Method and apparatus for synchronizing neural stimulation to cardiac cycles
US20070010862A1 (en) * 2005-04-26 2007-01-11 Thomas Osypka Apparatus and method for providing an electrical field to a targeted area
US7396326B2 (en) 2005-05-17 2008-07-08 Neuronetics, Inc. Ferrofluidic cooling and acoustical noise reduction in magnetic stimulators
FR2886835B1 (en) * 2005-06-14 2014-08-01 Hemodia INTEGRATED DEVICE FOR CONTROLLING CORTICAL ELECTRICAL ACTIVITY.
US7824324B2 (en) * 2005-07-27 2010-11-02 Neuronetics, Inc. Magnetic core for medical procedures
EP1926427A4 (en) * 2005-09-19 2012-06-06 Biolert Ltd A device and method for detecting an epileptic event
US20070088403A1 (en) * 2005-10-19 2007-04-19 Allen Wyler Methods and systems for establishing parameters for neural stimulation
US7729773B2 (en) 2005-10-19 2010-06-01 Advanced Neuromodualation Systems, Inc. Neural stimulation and optical monitoring systems and methods
US8929991B2 (en) 2005-10-19 2015-01-06 Advanced Neuromodulation Systems, Inc. Methods for establishing parameters for neural stimulation, including via performance of working memory tasks, and associated kits
US20070106143A1 (en) * 2005-11-08 2007-05-10 Flaherty J C Electrode arrays and related methods
US20070156126A1 (en) * 2005-12-29 2007-07-05 Flaherty J C Medical device insertion system and related methods
US7974697B2 (en) * 2006-01-26 2011-07-05 Cyberonics, Inc. Medical imaging feedback for an implantable medical device
CA2653110C (en) 2006-03-29 2018-07-31 Catholic Healthcare West Microburst electrical stimulation of cranial nerves for the treatment of medical conditions
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US8014866B2 (en) * 2006-07-13 2011-09-06 Cardiac Pacemakers, Inc. Variable voltage compliance for current output generator
US7869867B2 (en) 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
US8128549B2 (en) 2007-02-20 2012-03-06 Neuronetics, Inc. Capacitor failure detection
US20080249584A1 (en) * 2007-04-05 2008-10-09 Cardiac Pacemakers, Inc. Method and device for cardiosympathetic inhibition
US20080249591A1 (en) * 2007-04-06 2008-10-09 Northstar Neuroscience, Inc. Controllers for implantable medical devices, and associated methods
US20080261183A1 (en) * 2007-04-23 2008-10-23 Steven Donaldson Device for treating stuttering and method of using the same
US7974701B2 (en) 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
EP2170456A4 (en) * 2007-07-11 2016-09-21 Mayo Foundation Seizure forecasting, microseizure precursor events, and related therapeutic methods and devices
US8600512B2 (en) 2007-12-26 2013-12-03 Boston Scientific Neuromodulation Corporation Methods and systems for treating seizures caused by brain stimulation
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US11305121B2 (en) * 2013-03-15 2022-04-19 Flint Hills Scientific, Llc. Programmable autotitrating of electrical parameters of implantable medical device
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US9884200B2 (en) 2008-03-10 2018-02-06 Neuronetics, Inc. Apparatus for coil positioning for TMS studies
WO2009129493A1 (en) 2008-04-18 2009-10-22 Medtronic, Inc. Analyzing a washout period characteristic for psychiatric disorder therapy delivery
EP2274050A2 (en) * 2008-04-18 2011-01-19 Medtronic, Inc. Timing therapy evaluation trials
GB0817092D0 (en) * 2008-09-18 2008-10-29 To Be First Ag Cranial Electrostimulation method equipment and electrode unit
US8417344B2 (en) * 2008-10-24 2013-04-09 Cyberonics, Inc. Dynamic cranial nerve stimulation based on brain state determination from cardiac data
CN102202571A (en) * 2008-10-31 2011-09-28 内克斯蒂姆股份公司 Method, apparatus and computer program for non-invasive brain stimulation when target muscles are suitably active
US8239028B2 (en) * 2009-04-24 2012-08-07 Cyberonics, Inc. Use of cardiac parameters in methods and systems for treating a chronic medical condition
US8827912B2 (en) 2009-04-24 2014-09-09 Cyberonics, Inc. Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters
US20110213266A1 (en) * 2010-03-01 2011-09-01 Williams Justin C Closed Loop Neural Activity Triggered Rehabilitation Device And Method
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
US8679009B2 (en) 2010-06-15 2014-03-25 Flint Hills Scientific, Llc Systems approach to comorbidity assessment
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
EP4201475A1 (en) 2011-01-03 2023-06-28 The Regents of the University of California High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury
WO2012100260A2 (en) 2011-01-21 2012-07-26 California Institute Of Technology A parylene-based microelectrode array implant for spinal cord stimulation
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
CN103608069B (en) 2011-03-24 2017-03-29 加利福尼亚理工学院 Nerve stimulator
US9498162B2 (en) 2011-04-25 2016-11-22 Cyberonics, Inc. Identifying seizures using heart data from two or more windows
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
WO2012155189A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for estimating neural recruitment - f
US9872990B2 (en) 2011-05-13 2018-01-23 Saluda Medical Pty Limited Method and apparatus for application of a neural stimulus
AU2012255671B2 (en) 2011-05-13 2016-10-06 Saluda Medical Pty Limited Method and apparatus for measurement of neural response - a
US10588524B2 (en) 2011-05-13 2020-03-17 Saluda Medical Pty Ltd Method and apparatus for measurement of neural response
US10568559B2 (en) 2011-05-13 2020-02-25 Saluda Medical Pty Ltd Method and apparatus for measurement of neural response
US20120296395A1 (en) 2011-05-16 2012-11-22 Hamann Jason J Method and apparatus for neurostimulation with prevention of neural accommodation
US9549677B2 (en) 2011-10-14 2017-01-24 Flint Hills Scientific, L.L.C. Seizure detection methods, apparatus, and systems using a wavelet transform maximum modulus algorithm
ES2728143T3 (en) 2011-11-11 2019-10-22 Univ California Transcutaneous spinal cord stimulation: non-invasive tool for locomotor circuit activation
US10092750B2 (en) 2011-11-11 2018-10-09 Neuroenabling Technologies, Inc. Transcutaneous neuromodulation system and methods of using same
AU2012327234A1 (en) 2011-11-11 2013-05-30 Victor Reggie EDGERTON Non invasive neuromodulation device for enabling recovery of motor, sensory, autonomic, sexual, vasomotor and cognitive function
US9681836B2 (en) 2012-04-23 2017-06-20 Cyberonics, Inc. Methods, systems and apparatuses for detecting seizure and non-seizure states
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
DK2908904T3 (en) 2012-11-06 2020-12-14 Saluda Medical Pty Ltd SYSTEM FOR CONTROLING THE ELECTRICAL CONDITION OF TISSUE
US9731133B1 (en) 2013-01-22 2017-08-15 Nevro Corp. Systems and methods for systematically testing a plurality of therapy programs in patient therapy devices
US9295840B1 (en) 2013-01-22 2016-03-29 Nevro Corporation Systems and methods for automatically programming patient therapy devices
US9895538B1 (en) 2013-01-22 2018-02-20 Nevro Corp. Systems and methods for deploying patient therapy devices
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
AU2014228794B2 (en) 2013-03-15 2019-04-18 The Regents Of The University Of California Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion
US11229789B2 (en) 2013-05-30 2022-01-25 Neurostim Oab, Inc. Neuro activator with controller
KR102363552B1 (en) 2013-05-30 2022-02-15 그라함 에이치. 크리시 Topical neurological stimulation
CA2925754C (en) 2013-09-27 2023-02-21 The Regents Of The University Of California Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects
AU2014351064B2 (en) 2013-11-15 2019-07-04 Closed Loop Medical Pty Ltd Monitoring brain neural potentials
WO2015074121A1 (en) 2013-11-22 2015-05-28 Saluda Medical Pty Ltd Method and device for detecting a neural response in a neural measurement
WO2015106286A1 (en) 2014-01-13 2015-07-16 California Institute Of Technology Neuromodulation systems and methods of using same
CN105980004A (en) * 2014-02-11 2016-09-28 拉什大学医学中心 Self-contained, handheld bipolar cortical stimulator
CA2944042C (en) 2014-05-05 2023-08-29 Saluda Medical Pty Ltd Improved neural measurement
US10188869B2 (en) * 2014-07-21 2019-01-29 The Florida International University Board Of Trustees Hardware/software integrated design for a 3D tremor detector using TMS in Parkinson's disease and related disorders
EP3171929B1 (en) 2014-07-25 2021-03-24 Saluda Medical Pty Limited Neural stimulation dosing
KR101669436B1 (en) * 2014-08-08 2016-10-26 최상식 Head wearable type apparatus and method for managing state of user
WO2016025915A1 (en) 2014-08-15 2016-02-18 Axonics Modulation Technologies, Inc. Integrated electromyographic clinician programmer for use with an implantable neurostimulator
ES2705711T3 (en) 2014-08-15 2019-03-26 Axonics Modulation Tech Inc Positioning of electromyographic derivation and titration of stimulation in a nervous stimulation system for the treatment of overactive bladder
WO2016025912A1 (en) 2014-08-15 2016-02-18 Axonics Modulation Technologies, Inc. Systems and methods for neurostimulation electrode configurations based on neural localization
CA2958924C (en) 2014-08-21 2023-09-12 The Regents Of The University Of California Regulation of autonomic control of bladder voiding after a complete spinal cord injury
CA2959378A1 (en) 2014-08-27 2016-03-03 The Regents Of The University Of California Multi-electrode array for spinal cord epidural stimulation
US11006846B2 (en) 2014-11-17 2021-05-18 Saluda Medical Pty Ltd Method and device for detecting a neural response in neural measurements
AU2015362075B2 (en) 2014-12-11 2021-03-11 Saluda Medical Pty Ltd Implantable electrode positioning
WO2016090436A1 (en) 2014-12-11 2016-06-16 Saluda Medical Pty Ltd Method and device for feedback control of neural stimulation
US10918872B2 (en) 2015-01-19 2021-02-16 Saluda Medical Pty Ltd Method and device for neural implant communication
US11077301B2 (en) 2015-02-21 2021-08-03 NeurostimOAB, Inc. Topical nerve stimulator and sensor for bladder control
US9517344B1 (en) 2015-03-13 2016-12-13 Nevro Corporation Systems and methods for selecting low-power, effective signal delivery parameters for an implanted pulse generator
JP7071121B2 (en) 2015-04-09 2022-05-18 サルーダ・メディカル・ピーティーワイ・リミテッド Estimating the distance between the electrode and the nerve
CN107613860B (en) 2015-05-31 2022-01-11 闭环医疗私人有限公司 Cranial nerve activity monitoring
AU2016269837B2 (en) 2015-05-31 2021-10-21 Closed Loop Medical Pty Ltd Brain neurostimulator electrode fitting
WO2016191815A1 (en) 2015-06-01 2016-12-08 Saluda Medical Pty Ltd Motor fibre neuromodulation
WO2017035512A1 (en) 2015-08-26 2017-03-02 The Regents Of The University Of California Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject
DE102015114483A1 (en) * 2015-08-31 2017-03-02 Eberhard Karls Universität Tübingen Medizinische Fakultät Coil arrangement and system for transcranial magnetic stimulation
US11097122B2 (en) 2015-11-04 2021-08-24 The Regents Of The University Of California Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel
US10300277B1 (en) 2015-12-14 2019-05-28 Nevro Corp. Variable amplitude signals for neurological therapy, and associated systems and methods
CA3019701A1 (en) 2016-04-05 2017-10-12 Saluda Medical Pty Ltd Improved feedback control of neuromodulation
JP2019514652A (en) * 2016-04-27 2019-06-06 ニュクス テクノロジーズ インコーポレイテッドＮｅｕｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． Electrotherapy treatment
WO2017219096A1 (en) 2016-06-24 2017-12-28 Saluda Medical Pty Ltd Neural stimulation for reduced artefact
EP3974021B1 (en) 2017-06-30 2023-06-14 ONWARD Medical N.V. A system for neuromodulation
EP3684463A4 (en) 2017-09-19 2021-06-23 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement
CN111601636A (en) 2017-11-07 2020-08-28 Oab神经电疗科技公司 Non-invasive neural activator with adaptive circuit
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
US11318277B2 (en) 2017-12-31 2022-05-03 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
US11944820B2 (en) 2018-04-27 2024-04-02 Saluda Medical Pty Ltd Neurostimulation of mixed nerves
WO2020018912A1 (en) * 2018-07-19 2020-01-23 The Regents Of The University Of California Systems methods and devices for closed-loop stimulation to enhance stroke recovery
CA3112564A1 (en) 2018-09-14 2020-03-19 Neuroenhancement Lab, LLC System and method of improving sleep
DE18205821T1 (en) 2018-11-13 2020-12-24 Gtx Medical B.V. CONTROL SYSTEM FOR MOTION RECONSTRUCTION AND / OR RECOVERY FOR A PATIENT
EP3653260A1 (en) 2018-11-13 2020-05-20 GTX medical B.V. Sensor in clothing of limbs or footwear
EP3695878B1 (en) 2019-02-12 2023-04-19 ONWARD Medical N.V. A system for neuromodulation
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
US11439829B2 (en) 2019-05-24 2022-09-13 Axonics, Inc. Clinician programmer methods and systems for maintaining target operating temperatures
CN114126704A (en) 2019-06-26 2022-03-01 神经科学技术有限责任公司 Non-invasive neural activator with adaptive circuit
DE19211698T1 (en) 2019-11-27 2021-09-02 Onward Medical B.V. Neuromodulation system
WO2021126921A1 (en) 2019-12-16 2021-06-24 Neurostim Solutions, Llc Non-invasive nerve activator with boosted charge delivery

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5938688A (en) * 1997-10-22 1999-08-17 Cornell Research Foundation, Inc. Deep brain stimulation method

Family Cites Families (341)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2716226A (en) 1951-06-22 1955-08-23 Reiner Electronics Co Inc Electrical solderless connector
US2721316A (en) 1953-06-09 1955-10-18 Joseph D Shaw Method and means for aiding the blind
US3654933A (en) 1968-11-18 1972-04-11 Medtronic Inc Implatable electrode
US3628193A (en) 1969-02-19 1971-12-21 Inst Of Medical Sciences The Tactile image projection system
CH507005A (en) 1969-03-26 1971-05-15 Inst Medicina Farmacie Device for electrical neurostimulation for the evacuation of the neurogenic urinary bladder
US3595962A (en) * 1970-02-06 1971-07-27 Du Pont Method of using 4-arylbicyclo(2.2.2)octyl urethans as antidepressants and compositions thereof
US3850161A (en) 1973-04-09 1974-11-26 S Liss Method and apparatus for monitoring and counteracting excess brain electrical energy to prevent epileptic seizures and the like
US3918461A (en) 1974-01-31 1975-11-11 Irving S Cooper Method for electrically stimulating the human brain
US4019518A (en) 1975-08-11 1977-04-26 Medtronic, Inc. Electrical stimulation system
US4030509A (en) 1975-09-30 1977-06-21 Mieczyslaw Mirowski Implantable electrodes for accomplishing ventricular defibrillation and pacing and method of electrode implantation and utilization
US4125116A (en) 1977-02-14 1978-11-14 The Johns Hopkins University Human tissue stimulation electrode structure
US4140133A (en) 1977-04-26 1979-02-20 Moskovsky Oblastnoi Nauchno-Issledovatelsky Institut Akusherstva I Ginekolog Ii Device for pulse current action on central nervous system
CA1065969A (en) 1977-09-28 1979-11-06 Gratien Bouillon Self-blocking cerebral catheter
US4214804A (en) 1978-09-25 1980-07-29 Daig Corporation Press fit electrical connection apparatus
US4431000A (en) 1978-11-29 1984-02-14 Gatron Corporation Transcutaneous nerve stimulator with pseusorandom pulse generator
US4474186A (en) 1979-07-17 1984-10-02 Georgetown University Computerized electro-oculographic (CEOG) system with feedback control of stimuli
US4308868A (en) 1980-05-27 1982-01-05 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Implantable electrical device
US4341221A (en) 1980-10-07 1982-07-27 Medtronic, Inc. Shielded recording electrode system
US4328813A (en) 1980-10-20 1982-05-11 Medtronic, Inc. Brain lead anchoring system
US4340038A (en) 1980-12-15 1982-07-20 Pacesetter Systems, Inc. Magnetic field concentration means and method for an implanted device
US4390023A (en) 1981-04-30 1983-06-28 Medtronic, Inc. Patterned electrical tissue stimulator
CA1215128A (en) 1982-12-08 1986-12-09 Pedro Molina-Negro Electric nerve stimulator device
US4542752A (en) 1983-04-22 1985-09-24 Cordis Corporation Implantable device having porous surface with carbon coating
US4702254A (en) 1983-09-14 1987-10-27 Jacob Zabara Neurocybernetic prosthesis
US4844075A (en) * 1984-01-09 1989-07-04 Pain Suppression Labs, Inc. Transcranial stimulation for the treatment of cerebral palsy
US4607639A (en) 1984-05-18 1986-08-26 Regents Of The University Of California Method and system for controlling bladder evacuation
US4590946A (en) 1984-06-14 1986-05-27 Biomed Concepts, Inc. Surgically implantable electrode for nerve bundles
US4646744A (en) 1984-06-29 1987-03-03 Zion Foundation Method and treatment with transcranially applied electrical signals
CA1292285C (en) 1985-08-21 1991-11-19 Paul H. Stypulkowski External ear canal electrode to be placed proximate the tympanic membrane and method of stimulating/recording utilizing external ear canal electrode placed proximate the tympanic membrane
US5054906A (en) 1986-01-17 1991-10-08 Brimfield Precision, Inc. Indirectly illuminating ophthalmological speculum
US5330520A (en) 1986-05-15 1994-07-19 Telectronics Pacing Systems, Inc. Implantable electrode and sensor lead apparatus
US4969468A (en) 1986-06-17 1990-11-13 Alfred E. Mann Foundation For Scientific Research Electrode array for use in connection with a living body and method of manufacture
US4774967A (en) 1986-09-09 1988-10-04 American Biointerface Corporation Method and apparatus for mammalian nerve regeneration
US4983322A (en) 1987-01-12 1991-01-08 Allied-Signal Inc. Solution processible forms of electrically conductive polyaniline
US4949140A (en) 1987-02-02 1990-08-14 Intel Corporation EEPROM cell with integral select transistor
US5030225A (en) 1987-03-13 1991-07-09 Brown University Research Foundation Electrically-charged nerve guidance channels
US4817634A (en) 1987-06-18 1989-04-04 Medtronic, Inc. Epicardial patch electrode
US4779630A (en) 1987-09-18 1988-10-25 Katecho, Inc. Defibrillator pad assembly and method for using same
DE3887263T2 (en) 1987-10-26 1994-05-19 Nippon Denso Co Fuel supply device for vehicles.
US4869255A (en) 1987-12-04 1989-09-26 Ad-Tech Medical Instrument Corp. Electrical connection device
US4865048A (en) 1987-12-31 1989-09-12 Eckerson Harold D Method and apparatus for drug free neurostimulation
US5073114A (en) 1988-02-23 1991-12-17 Detsch Steven G Bone growing method and composition
US4903702A (en) 1988-10-17 1990-02-27 Ad-Tech Medical Instrument Corporation Brain-contact for sensing epileptogenic foci with improved accuracy
US5002053A (en) 1989-04-21 1991-03-26 University Of Arkansas Method of and device for inducing locomotion by electrical stimulation of the spinal cord
DE3914662A1 (en) 1989-05-03 1990-11-08 Alt Eckhard DEVICE FOR TRANSMITTING ELECTRICAL SIGNALS BETWEEN AN IMPLANTABLE MEDICAL DEVICE AND ELECTRICALLY EXPENSIBLE HUMAN TISSUE
US5130412A (en) 1989-08-08 1992-07-14 Southwest Research Institute Electrochemical drug release and article
SG49267A1 (en) 1989-08-14 1998-05-18 Photogenesis Inc Surgical instrument and cell isolation and transplantation
US5817075A (en) 1989-08-14 1998-10-06 Photogenesis, Inc. Method for preparation and transplantation of planar implants and surgical instrument therefor
US5024226A (en) 1989-08-17 1991-06-18 Critikon, Inc. Epidural oxygen sensor
US5063932A (en) 1989-10-03 1991-11-12 Mieczyslaw Mirowski Controlled discharge defibrillation electrode
US5215088A (en) 1989-11-07 1993-06-01 The University Of Utah Three-dimensional electrode device
US5271417A (en) 1990-01-23 1993-12-21 Cardiac Pacemakers, Inc. Defibrillation electrode having smooth current distribution
US5031618A (en) 1990-03-07 1991-07-16 Medtronic, Inc. Position-responsive neuro stimulator
US5044368A (en) 1990-04-23 1991-09-03 Ad-Tech Medical Instrument Corporation Diagnostic electrode for use with magnetic resonance imaging
US5713926A (en) 1990-04-25 1998-02-03 Cardiac Pacemakers, Inc. Implantable intravenous cardiac stimulation system with pulse generator housing serving as optional additional electrode
US5314458A (en) 1990-06-01 1994-05-24 University Of Michigan Single channel microstimulator
US5095905A (en) 1990-06-07 1992-03-17 Medtronic, Inc. Implantable neural electrode
US5092835A (en) 1990-07-06 1992-03-03 Schurig Janet L S Brain and nerve healing power apparatus and method
US6196226B1 (en) 1990-08-10 2001-03-06 University Of Washington Methods and apparatus for optically imaging neuronal tissue and activity
US5121754A (en) 1990-08-21 1992-06-16 Medtronic, Inc. Lateral displacement percutaneously inserted epidural lead
US5618531A (en) 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord
US5224491A (en) 1991-01-07 1993-07-06 Medtronic, Inc. Implantable electrode for location within a blood vessel
US5269303A (en) 1991-02-22 1993-12-14 Cyberonics, Inc. Treatment of dementia by nerve stimulation
US5299569A (en) 1991-05-03 1994-04-05 Cyberonics, Inc. Treatment of neuropsychiatric disorders by nerve stimulation
US5215086A (en) 1991-05-03 1993-06-01 Cyberonics, Inc. Therapeutic treatment of migraine symptoms by stimulation
US5269302A (en) * 1991-05-10 1993-12-14 Somatics, Inc. Electroconvulsive therapy apparatus and method for monitoring patient seizures
US5255678A (en) 1991-06-21 1993-10-26 Ecole Polytechnique Mapping electrode balloon
US5750376A (en) 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
US5169384A (en) 1991-08-16 1992-12-08 Bosniak Stephen L Apparatus for facilitating post-traumatic, post-surgical, and/or post-inflammatory healing of tissue
US6214334B1 (en) 1991-10-21 2001-04-10 Trustees Of The University Of Pennsylvania Compositions and methods for producing and using homogenous neuronal cell transplants to treat neurodegenerative disorders and brain and spinal cord injuries
US5304206A (en) 1991-11-18 1994-04-19 Cyberonics, Inc. Activation techniques for implantable medical device
US5193540A (en) 1991-12-18 1993-03-16 Alfred E. Mann Foundation For Scientific Research Structure and method of manufacture of an implantable microstimulator
US5358514A (en) 1991-12-18 1994-10-25 Alfred E. Mann Foundation For Scientific Research Implantable microdevice with self-attaching electrodes
US5184620A (en) 1991-12-26 1993-02-09 Marquette Electronics, Inc. Method of using a multiple electrode pad assembly
US5753502A (en) 1993-08-05 1998-05-19 Icos Corporation Neuron-specific ICAM-4 promoter
US5406957A (en) 1992-02-05 1995-04-18 Tansey; Michael A. Electroencephalic neurofeedback apparatus for training and tracking of cognitive states
US5303705A (en) 1992-05-01 1994-04-19 Nenov Valeriy I Evoked 23NA MR imaging of sodium currents in the brain
US5263967B1 (en) 1992-05-15 2000-12-19 Brimfield Prec Inc Medical instrument with dual action drive
US5476494A (en) 1992-09-11 1995-12-19 Massachusetts Institute Of Technology Low pressure neural contact structure
US5441528A (en) 1992-09-25 1995-08-15 Symtonic, S.A. Method and system for applying low energy emission therapy
US5370672A (en) 1992-10-30 1994-12-06 The Johns Hopkins University Computer-controlled neurological stimulation system
US5358513A (en) 1992-12-09 1994-10-25 Medtronic, Inc. Parameter selection and electrode placement of neuromuscular electrical stimulation apparatus
SE9203734D0 (en) 1992-12-11 1992-12-11 Siemens Elema Ab defibrillation
ES2170096T3 (en) 1993-04-13 2002-08-01 Us Gov Health & Human Serv USE OF NEURODERIVED FETAL CELLULAR LINES FOR TRANSPLANTATION THERAPY.
US5537512A (en) 1993-05-26 1996-07-16 Northrop Grumman Corporation Neural network elements
US5411540A (en) 1993-06-03 1995-05-02 Massachusetts Institute Of Technology Method and apparatus for preferential neuron stimulation
US5593432A (en) 1993-06-23 1997-01-14 Neuroware Therapy International, Inc. Method for neurostimulation for pain alleviation
US5540736A (en) 1993-08-02 1996-07-30 Haimovich; Yechiel Transcranial electrostimulation apparatus having two electrode pairs and independent current generators
US5417719A (en) 1993-08-25 1995-05-23 Medtronic, Inc. Method of using a spinal cord stimulation lead
US5464446A (en) 1993-10-12 1995-11-07 Medtronic, Inc. Brain lead anchoring system
US5840689A (en) 1993-10-29 1998-11-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method for stimulating the regrowth of neurons
US5470846A (en) 1994-01-14 1995-11-28 Sandyk; Reuven Treatment of neurological and mental disorders
US5405375A (en) 1994-01-21 1995-04-11 Incontrol, Inc. Combined mapping, pacing, and defibrillating catheter
US5843093A (en) 1994-02-09 1998-12-01 University Of Iowa Research Foundation Stereotactic electrode assembly
US5697975A (en) 1994-02-09 1997-12-16 The University Of Iowa Research Foundation Human cerebral cortex neural prosthetic for tinnitus
US5562708A (en) 1994-04-21 1996-10-08 Medtronic, Inc. Method and apparatus for treatment of atrial fibrillation
US5769778A (en) 1994-04-22 1998-06-23 Somatics, Inc. Medical magnetic non-convulsive stimulation therapy
US6152143A (en) 1994-05-09 2000-11-28 Somnus Medical Technologies, Inc. Method for treatment of air way obstructions
US5685313A (en) 1994-05-31 1997-11-11 Brain Monitor Ltd. Tissue monitor
US5601611A (en) 1994-08-05 1997-02-11 Ventritex, Inc. Optical blood flow measurement apparatus and method and implantable defibrillator incorporating same
US5549655A (en) 1994-09-21 1996-08-27 Medtronic, Inc. Method and apparatus for synchronized treatment of obstructive sleep apnea
US5540734A (en) 1994-09-28 1996-07-30 Zabara; Jacob Cranial nerve stimulation treatments using neurocybernetic prosthesis
US5722401A (en) 1994-10-19 1998-03-03 Cardiac Pathways Corporation Endocardial mapping and/or ablation catheter probe
US5522864A (en) 1994-10-25 1996-06-04 Wallace; Larry B. Apparatus and method for ocular treatment
US5520190A (en) 1994-10-31 1996-05-28 Ventritex, Inc. Cardiac blood flow sensor and method
US5641680A (en) 1994-11-14 1997-06-24 Zhao; Xi Gene transfer apparatus and method for using the same
US6425852B1 (en) 1994-11-28 2002-07-30 Emory University Apparatus and method for transcranial magnetic brain stimulation, including the treatment of depression and the localization and characterization of speech arrest
US6132361A (en) 1994-11-28 2000-10-17 Neotonus, Inc. Transcranial brain stimulation
JP3181202B2 (en) * 1995-03-27 2001-07-03 三菱重工業株式会社 Dewatering equipment for paper machine twin wire former
US5545186A (en) 1995-03-30 1996-08-13 Medtronic, Inc. Prioritized rule based method and apparatus for diagnosis and treatment of arrhythmias
US5885976A (en) 1995-05-08 1999-03-23 Sandyk; Reuven Methods useful for the treatment of neurological and mental disorders related to deficient serotonin neurotransmission and impaired pineal melatonin functions
US5591216A (en) 1995-05-19 1997-01-07 Medtronic, Inc. Method for treatment of sleep apnea by electrical stimulation
US5772591A (en) 1995-06-06 1998-06-30 Patient Comfort, Inc. Electrode assembly for signaling a monitor
US6111911A (en) 1995-06-07 2000-08-29 Sanconix, Inc Direct sequence frequency ambiguity resolving receiver
US5753505A (en) 1995-07-06 1998-05-19 Emory University Neuronal progenitor cells and uses thereof
US6057846A (en) 1995-07-14 2000-05-02 Sever, Jr.; Frank Virtual reality psychophysiological conditioning medium
US5707334A (en) 1995-08-21 1998-01-13 Young; Robert B. Method of treating amygdala related transitory disorders
AUPN533195A0 (en) 1995-09-07 1995-10-05 Cochlear Pty. Limited Derived threshold and comfort level for auditory prostheses
US5649936A (en) 1995-09-19 1997-07-22 Real; Douglas D. Stereotactic guide apparatus for use with neurosurgical headframe
US5782873A (en) 1995-10-11 1998-07-21 Trustees Of Boston University Method and apparatus for improving the function of sensory cells
US6944501B1 (en) 2000-04-05 2005-09-13 Neurospace, Inc. Neurostimulator involving stimulation strategies and process for using it
US6480743B1 (en) 2000-04-05 2002-11-12 Neuropace, Inc. System and method for adaptive brain stimulation
US20020169485A1 (en) 1995-10-16 2002-11-14 Neuropace, Inc. Differential neurostimulation therapy driven by physiological context
US6095148A (en) 1995-11-03 2000-08-01 Children's Medical Center Corporation Neuronal stimulation using electrically conducting polymers
AU731837B2 (en) 1995-12-01 2001-04-05 Cochlear Limited A feedback system to control electrode voltages in a cochlear stimulator and the like
NL1001890C2 (en) 1995-12-13 1997-06-17 Cordis Europ Catheter with plate-shaped electrode array.
US5824030A (en) 1995-12-21 1998-10-20 Pacesetter, Inc. Lead with inter-electrode spacing adjustment
US5995868A (en) * 1996-01-23 1999-11-30 University Of Kansas System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain of a subject
US6066163A (en) 1996-02-02 2000-05-23 John; Michael Sasha Adaptive brain stimulation method and system
US6463328B1 (en) 1996-02-02 2002-10-08 Michael Sasha John Adaptive brain stimulation method and system
US5611350A (en) 1996-02-08 1997-03-18 John; Michael S. Method and apparatus for facilitating recovery of patients in deep coma
US6051017A (en) 1996-02-20 2000-04-18 Advanced Bionics Corporation Implantable microstimulator and systems employing the same
US6126657A (en) 1996-02-23 2000-10-03 Somnus Medical Technologies, Inc. Apparatus for treatment of air way obstructions
US5904916A (en) 1996-03-05 1999-05-18 Hirsch; Alan R. Use of odorants to alter learning capacity
US5833603A (en) 1996-03-13 1998-11-10 Lipomatrix, Inc. Implantable biosensing transponder
EP0796634B1 (en) 1996-03-21 2005-11-16 BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin Implantable stimulation electrode
US5628317A (en) 1996-04-04 1997-05-13 Medtronic, Inc. Ultrasonic techniques for neurostimulator control
AU714617B2 (en) 1996-04-04 2000-01-06 Medtronic, Inc. Living tissue stimulation and recording techniques
US5925070A (en) 1996-04-04 1999-07-20 Medtronic, Inc. Techniques for adjusting the locus of excitation of electrically excitable tissue
US5713922A (en) 1996-04-25 1998-02-03 Medtronic, Inc. Techniques for adjusting the locus of excitation of neural tissue in the spinal cord or brain
US5702429A (en) 1996-04-04 1997-12-30 Medtronic, Inc. Neural stimulation techniques with feedback
US5767252A (en) 1996-04-08 1998-06-16 The Johns Hopkins University School Of Medicine Neuronal cell growth factor, Narp
US5716377A (en) 1996-04-25 1998-02-10 Medtronic, Inc. Method of treating movement disorders by brain stimulation
US5683422A (en) 1996-04-25 1997-11-04 Medtronic, Inc. Method and apparatus for treating neurodegenerative disorders by electrical brain stimulation
US5824021A (en) 1996-04-25 1998-10-20 Medtronic Inc. Method and apparatus for providing feedback to spinal cord stimulation for angina
US6094598A (en) 1996-04-25 2000-07-25 Medtronics, Inc. Method of treating movement disorders by brain stimulation and drug infusion
US5735814A (en) 1996-04-30 1998-04-07 Medtronic, Inc. Techniques of treating neurodegenerative disorders by brain infusion
US5711316A (en) 1996-04-30 1998-01-27 Medtronic, Inc. Method of treating movement disorders by brain infusion
US5713923A (en) 1996-05-13 1998-02-03 Medtronic, Inc. Techniques for treating epilepsy by brain stimulation and drug infusion
US5753506A (en) 1996-05-23 1998-05-19 Cns Stem Cell Technology, Inc. Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
AU3304997A (en) 1996-05-31 1998-01-05 Southern Illinois University Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation
US6609031B1 (en) 1996-06-07 2003-08-19 Advanced Neuromodulation Systems, Inc. Multiprogrammable tissue stimulator and method
US5782798A (en) 1996-06-26 1998-07-21 Medtronic, Inc. Techniques for treating eating disorders by brain stimulation and drug infusion
US6021352A (en) 1996-06-26 2000-02-01 Medtronic, Inc, Diagnostic testing methods and apparatus for implantable therapy devices
US6246912B1 (en) 1996-06-27 2001-06-12 Sherwood Services Ag Modulated high frequency tissue modification
US5817784A (en) 1996-08-09 1998-10-06 Amgen Inc. Neurogene
US5865842A (en) 1996-08-29 1999-02-02 Medtronic, Inc. System and method for anchoring brain stimulation lead or catheter
US5797970A (en) 1996-09-04 1998-08-25 Medtronic, Inc. System, adaptor and method to provide medical electrical stimulation
US5843148A (en) 1996-09-27 1998-12-01 Medtronic, Inc. High resolution brain stimulation lead and method of use
US5752979A (en) 1996-11-01 1998-05-19 Medtronic, Inc. Method of controlling epilepsy by brain stimulation
US6057847A (en) 1996-12-20 2000-05-02 Jenkins; Barry System and method of image generation and encoding using primitive reprojection
US6026326A (en) 1997-01-13 2000-02-15 Medtronic, Inc. Apparatus and method for treating chronic constipation
US5871517A (en) 1997-01-15 1999-02-16 Somatics, Inc. Convulsive therapy apparatus to stimulate and monitor the extent of therapeutic value of the treatment
US5792188A (en) 1997-01-23 1998-08-11 Pacesetter, Inc. Capacitor reformation and measurement in an implantable cardioverter/defibrillator (ICD)
US6331406B1 (en) 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use
US5893883A (en) 1997-04-30 1999-04-13 Medtronic, Inc. Portable stimulation screening device for screening therapeutic effect of electrical stimulation on a patient user during normal activities of the patient user
US5948007A (en) 1997-04-30 1999-09-07 Medtronic, Inc. Dual channel implantation neurostimulation techniques
US6042579A (en) 1997-04-30 2000-03-28 Medtronic, Inc. Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain
US5975085A (en) 1997-05-01 1999-11-02 Medtronic, Inc. Method of treating schizophrenia by brain stimulation and drug infusion
US6128537A (en) * 1997-05-01 2000-10-03 Medtronic, Inc Techniques for treating anxiety by brain stimulation and drug infusion
US6238429B1 (en) 1997-05-05 2001-05-29 Medtronic, Inc. Biologic cabling
US6393319B1 (en) 1997-05-06 2002-05-21 Christopher Bock Methods and apparatus for portable delivery of electrical physical modalities to a patient
US5861017A (en) 1997-06-06 1999-01-19 Shriners Hospitals For Children Portable functional electrical stimulation (FES) system for upper or lower extremity applications
US6024702A (en) 1997-09-03 2000-02-15 Pmt Corporation Implantable electrode manufactured with flexible printed circuit
US5843150A (en) 1997-10-08 1998-12-01 Medtronic, Inc. System and method for providing electrical and/or fluid treatment within a patient's brain
US5941906A (en) 1997-10-15 1999-08-24 Medtronic, Inc. Implantable, modular tissue stimulator
US6597954B1 (en) 1997-10-27 2003-07-22 Neuropace, Inc. System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes
US6459936B2 (en) 1997-10-27 2002-10-01 Neuropace, Inc. Methods for responsively treating neurological disorders
US6427086B1 (en) 1997-10-27 2002-07-30 Neuropace, Inc. Means and method for the intracranial placement of a neurostimulator
US6230049B1 (en) * 1999-08-13 2001-05-08 Neuro Pace, Inc. Integrated system for EEG monitoring and electrical stimulation with a multiplicity of electrodes
US6647296B2 (en) 1997-10-27 2003-11-11 Neuropace, Inc. Implantable apparatus for treating neurological disorders
US6354299B1 (en) 1997-10-27 2002-03-12 Neuropace, Inc. Implantable device for patient communication
US6016449A (en) 1997-10-27 2000-01-18 Neuropace, Inc. System for treatment of neurological disorders
US6151525A (en) 1997-11-07 2000-11-21 Medtronic, Inc. Method and system for myocardial identifier repair
DE19750043A1 (en) 1997-11-12 1999-05-20 Johann W Prof Dr Bartha Novel cuff electrode and method for producing it
US6128527A (en) 1997-12-03 2000-10-03 University Of Iowa Research Foundation Apparatus and method of analyzing electrical brain activity
US6082364A (en) 1997-12-15 2000-07-04 Musculoskeletal Development Enterprises, Llc Pluripotential bone marrow cell line and methods of using the same
US6011996A (en) 1998-01-20 2000-01-04 Medtronic, Inc Dual electrode lead and method for brain target localization in functional stereotactic brain surgery
US6208893B1 (en) 1998-01-27 2001-03-27 Genetronics, Inc. Electroporation apparatus with connective electrode template
US6205361B1 (en) 1998-02-10 2001-03-20 Advanced Bionics Corporation Implantable expandable multicontact electrodes
US6227203B1 (en) 1998-02-12 2001-05-08 Medtronic, Inc. Techniques for controlling abnormal involuntary movements by brain stimulation and drug infusion
US6078838A (en) 1998-02-13 2000-06-20 University Of Iowa Research Foundation Pseudospontaneous neural stimulation system and method
US6631295B2 (en) 1998-02-13 2003-10-07 University Of Iowa Research Foundation System and method for diagnosing and/or reducing tinnitus
US5999584A (en) 1998-02-23 1999-12-07 Framatome Technologies, Inc. Reactor head lift apparatus
US6221908B1 (en) 1998-03-12 2001-04-24 Scientific Learning Corporation System for stimulating brain plasticity
US6847614B2 (en) 1998-04-20 2005-01-25 Broadcom Corporation Apparatus and method for unilateral topology discovery in network management
US6058331A (en) 1998-04-27 2000-05-02 Medtronic, Inc. Apparatus and method for treating peripheral vascular disease and organ ischemia by electrical stimulation with closed loop feedback control
US6421566B1 (en) 1998-04-30 2002-07-16 Medtronic, Inc. Selective dorsal column stimulation in SCS, using conditioning pulses
US6018682A (en) 1998-04-30 2000-01-25 Medtronic, Inc. Implantable seizure warning system
US6161047A (en) 1998-04-30 2000-12-12 Medtronic Inc. Apparatus and method for expanding a stimulation lead body in situ
US6319241B1 (en) 1998-04-30 2001-11-20 Medtronic, Inc. Techniques for positioning therapy delivery elements within a spinal cord or a brain
US5938689A (en) 1998-05-01 1999-08-17 Neuropace, Inc. Electrode configuration for a brain neuropacemaker
US6006124A (en) 1998-05-01 1999-12-21 Neuropace, Inc. Means and method for the placement of brain electrodes
US5886769A (en) 1998-05-18 1999-03-23 Zolten; A. J. Method of training and rehabilitating brain function using hemi-lenses
US6198958B1 (en) 1998-06-11 2001-03-06 Beth Israel Deaconess Medical Center, Inc. Method and apparatus for monitoring a magnetic resonance image during transcranial magnetic stimulation
US7890176B2 (en) 1998-07-06 2011-02-15 Boston Scientific Neuromodulation Corporation Methods and systems for treating chronic pelvic pain
US6104960A (en) 1998-07-13 2000-08-15 Medtronic, Inc. System and method for providing medical electrical stimulation to a portion of the nervous system
US6035236A (en) 1998-07-13 2000-03-07 Bionergy Therapeutics, Inc. Methods and apparatus for electrical microcurrent stimulation therapy
US6366813B1 (en) * 1998-08-05 2002-04-02 Dilorenzo Daniel J. Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US7277758B2 (en) 1998-08-05 2007-10-02 Neurovista Corporation Methods and systems for predicting future symptomatology in a patient suffering from a neurological or psychiatric disorder
US6949081B1 (en) 1998-08-26 2005-09-27 Non-Invasive Technology, Inc. Sensing and interactive drug delivery
US6304787B1 (en) 1998-08-26 2001-10-16 Advanced Bionics Corporation Cochlear electrode array having current-focusing and tissue-treating features
DE69840710D1 (en) 1998-08-27 2009-05-14 Novavision Inc DEVICE FOR TRAINING HUMAN VISION
US6149612A (en) 1998-09-14 2000-11-21 Schnapp; Moacir Rehabilitative apparatus for treating reflex sympathetic dystrophy
US6190893B1 (en) 1998-09-18 2001-02-20 Massachusetts Institute Of Technology Electroactive materials for stimulation of biological activity of bone marrow stromal cells
US6569654B2 (en) 1998-09-18 2003-05-27 Massachusetts Institute Of Technology Electroactive materials for stimulation of biological activity of stem cells
USRE45616E1 (en) 1998-10-13 2015-07-21 Covidien Lp Multi-channel non-invasive tissue oximeter
US20060217782A1 (en) 1998-10-26 2006-09-28 Boveja Birinder R Method and system for cortical stimulation to provide adjunct (ADD-ON) therapy for stroke, tinnitus and other medical disorders using implantable and external components
US7062330B1 (en) 1998-10-26 2006-06-13 Boveja Birinder R Electrical stimulation adjunct (Add-ON) therapy for urinary incontinence and urological disorders using implanted lead stimulus-receiver and an external pulse generator
US6253109B1 (en) 1998-11-05 2001-06-26 Medtronic Inc. System for optimized brain stimulation
US6161044A (en) 1998-11-23 2000-12-12 Synaptic Corporation Method and apparatus for treating chronic pain syndromes, tremor, dementia and related disorders and for inducing electroanesthesia using high frequency, high intensity transcutaneous electrical nerve stimulation
US6507755B1 (en) 1998-12-01 2003-01-14 Neurometrix, Inc. Apparatus and method for stimulating human tissue
US7110473B2 (en) 1998-12-11 2006-09-19 Freescale Semiconductor, Inc. Mode controller for signal acquisition and tracking in an ultra wideband communication system
US6052624A (en) 1999-01-07 2000-04-18 Advanced Bionics Corporation Directional programming for implantable electrode arrays
US6152882A (en) 1999-01-26 2000-11-28 Impulse Dynamics N.V. Apparatus and method for chronic measurement of monophasic action potentials
EP1163026A1 (en) 1999-03-24 2001-12-19 Lloyd R. Saberski Apparatus and methods for reducing pain and/or retraining muscles
US6055456A (en) 1999-04-29 2000-04-25 Medtronic, Inc. Single and multi-polar implantable lead for sacral nerve electrical stimulation
US6210417B1 (en) 1999-04-29 2001-04-03 Medtronic, Inc. Medical lead positioning and anchoring system
US6353762B1 (en) 1999-04-30 2002-03-05 Medtronic, Inc. Techniques for selective activation of neurons in the brain, spinal cord parenchyma or peripheral nerve
US6176242B1 (en) 1999-04-30 2001-01-23 Medtronic Inc Method of treating manic depression by brain infusion
EP1180056B1 (en) 1999-05-11 2003-11-12 Exogen, Inc. Apparatus for ultrasonic treatment of reflex sympathetic dystrophy
US6505075B1 (en) 1999-05-29 2003-01-07 Richard L. Weiner Peripheral nerve stimulation method
US6161045A (en) 1999-06-01 2000-12-12 Neuropace, Inc. Method for determining stimulation parameters for the treatment of epileptic seizures
WO2000074769A2 (en) 1999-06-07 2000-12-14 Johns Hopkins University Cardiac shock electrode system and corresponding implantable defibrillator system
US6539263B1 (en) 1999-06-11 2003-03-25 Cornell Research Foundation, Inc. Feedback mechanism for deep brain stimulation
US6301493B1 (en) 1999-07-10 2001-10-09 Physiometrix, Inc. Reservoir electrodes for electroencephalograph headgear appliance
US6516227B1 (en) 1999-07-27 2003-02-04 Advanced Bionics Corporation Rechargeable spinal cord stimulator system
AU766096B2 (en) 1999-08-17 2003-10-09 Trustees Of The University Of Pennsylvania, The Mechanically elongated neuronal cells and methods for producing and using these cells
US6381496B1 (en) 1999-10-01 2002-04-30 Advanced Bionics Corporation Parameter context switching for an implanted device
US6236892B1 (en) 1999-10-07 2001-05-22 Claudio A. Feler Spinal cord stimulation lead
US6499488B1 (en) 1999-10-28 2002-12-31 Winchester Development Associates Surgical sensor
US6727818B1 (en) 1999-10-29 2004-04-27 Hill-Rom Services, Inc. Hygiene monitoring system
US7300449B2 (en) 1999-12-09 2007-11-27 Mische Hans A Methods and devices for the treatment of neurological and physiological disorders
US6764498B2 (en) 1999-12-09 2004-07-20 Hans Alois Mische Methods and devices for treatment of neurological disorders
US6375666B1 (en) 1999-12-09 2002-04-23 Hans Alois Mische Methods and devices for treatment of neurological disorders
AU1547101A (en) 1999-11-26 2001-06-04 Applied Spectral Imaging Ltd. System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same
WO2001039664A1 (en) 1999-12-02 2001-06-07 The General Hospital Corporation Method and apparatus for measuring indices of brain activity
WO2001039831A1 (en) 1999-12-06 2001-06-07 Advanced Bionics Corporation Implantable device programmer
AU782860B2 (en) 1999-12-07 2005-09-01 Krasnow Institute Adaptive electric field modulation of neural systems
US6873872B2 (en) 1999-12-07 2005-03-29 George Mason University Adaptive electric field modulation of neural systems
US6658299B1 (en) 2000-01-04 2003-12-02 William H. Dobelle Artificial system for vision and the like
US6356786B1 (en) 2000-01-20 2002-03-12 Electrocore Techniques, Llc Method of treating palmar hyperhydrosis by electrical stimulation of the sympathetic nervous chain
US6356792B1 (en) 2000-01-20 2002-03-12 Electro Core Technologies, Llc Skull mounted electrode lead securing assembly
US6907296B1 (en) 2000-02-15 2005-06-14 Pacesetter, Inc. Implantable cardiac lead having convenient implant location identification and method of manufacture
US6609030B1 (en) 2000-02-24 2003-08-19 Electrocore Techniques, Llc Method of treating psychiatric diseases by neuromodulation within the dorsomedial thalamus
US6487450B1 (en) 2000-02-24 2002-11-26 Cedars-Sinai Medical Center System and method for preventing Sudden Cardiac Death by nerve sprouting from right stellate ganglion
US6708064B2 (en) 2000-02-24 2004-03-16 Ali R. Rezai Modulation of the brain to affect psychiatric disorders
US6418344B1 (en) 2000-02-24 2002-07-09 Electrocore Techniques, Llc Method of treating psychiatric disorders by electrical stimulation within the orbitofrontal cerebral cortex
US6473639B1 (en) 2000-03-02 2002-10-29 Neuropace, Inc. Neurological event detection procedure using processed display channel based algorithms and devices incorporating these procedures
US6810286B2 (en) 2000-03-06 2004-10-26 Medtronic, Inc Stimulation for delivery of molecular therapy
US6466822B1 (en) * 2000-04-05 2002-10-15 Neuropace, Inc. Multimodal neurostimulator and process of using it
US6353754B1 (en) 2000-04-24 2002-03-05 Neuropace, Inc. System for the creation of patient specific templates for epileptiform activity detection
US6687525B2 (en) 2000-06-07 2004-02-03 New York University Method and system for diagnosing and treating thalamocortical dysrhythmia
US6549814B1 (en) 2000-06-09 2003-04-15 Juergen Strutz Blade electrode array for insertion under soft tissue of lateral wall of cochlea
AU2001268473A1 (en) 2000-06-20 2002-01-02 Advanced Bionics Corporation Apparatus for treatment of mood and/or anxiety disorders by electrical brain stimulation and/or drug infusion
US7236831B2 (en) 2000-07-13 2007-06-26 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7146217B2 (en) 2000-07-13 2006-12-05 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a change in a neural-function of a patient
US7756584B2 (en) 2000-07-13 2010-07-13 Advanced Neuromodulation Systems, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US20030125786A1 (en) 2000-07-13 2003-07-03 Gliner Bradford Evan Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7672730B2 (en) 2001-03-08 2010-03-02 Advanced Neuromodulation Systems, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US20050021118A1 (en) 2000-07-13 2005-01-27 Chris Genau Apparatuses and systems for applying electrical stimulation to a patient
US20040176831A1 (en) 2000-07-13 2004-09-09 Gliner Bradford Evan Apparatuses and systems for applying electrical stimulation to a patient
US7305268B2 (en) 2000-07-13 2007-12-04 Northstar Neurscience, Inc. Systems and methods for automatically optimizing stimulus parameters and electrode configurations for neuro-stimulators
US7010351B2 (en) 2000-07-13 2006-03-07 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7831305B2 (en) 2001-10-15 2010-11-09 Advanced Neuromodulation Systems, Inc. Neural stimulation system and method responsive to collateral neural activity
US7024247B2 (en) 2001-10-15 2006-04-04 Northstar Neuroscience, Inc. Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures
US6497699B1 (en) 2000-08-09 2002-12-24 The Research Foundation Of State University Of New York Hybrid neuroprosthesis for the treatment of brain disorders
DE10039240A1 (en) 2000-08-11 2002-02-28 Hans Ulrich May Electrotherapeutic device
US6591138B1 (en) 2000-08-31 2003-07-08 Neuropace, Inc. Low frequency neurostimulator for the treatment of neurological disorders
JP2002072309A (en) 2000-09-01 2002-03-12 Canon Inc Camera and camera system
US6405079B1 (en) 2000-09-22 2002-06-11 Mehdi M. Ansarinia Stimulation method for the dural venous sinuses and adjacent dura for treatment of medical conditions
US6898464B2 (en) 2000-10-05 2005-05-24 Innersea Technology Optical telemetry of data and power for wireless biomedical sensors and actuators
US6871098B2 (en) 2000-10-30 2005-03-22 Medtronic, Inc. Method for treating obsessive-compulsive disorder with electrical stimulation of the brain internal capsule
US6529774B1 (en) 2000-11-09 2003-03-04 Neuropace, Inc. Extradural leads, neurostimulator assemblies, and processes of using them for somatosensory and brain stimulation
US6922590B1 (en) 2000-11-21 2005-07-26 Advanced Bionics Corporation Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion
US6735475B1 (en) 2001-01-30 2004-05-11 Advanced Bionics Corporation Fully implantable miniature neurostimulator for stimulation as a therapy for headache and/or facial pain
US6788975B1 (en) 2001-01-30 2004-09-07 Advanced Bionics Corporation Fully implantable miniature neurostimulator for stimulation as a therapy for epilepsy
US7149586B2 (en) 2002-03-28 2006-12-12 Second Sight Medical Products, Inc. Variable pitch electrode array
US7299096B2 (en) 2001-03-08 2007-11-20 Northstar Neuroscience, Inc. System and method for treating Parkinson's Disease and other movement disorders
WO2002073526A2 (en) 2001-03-13 2002-09-19 Wide Horizon Holdings Inc. Cerebral programming
US7010856B2 (en) 2001-03-16 2006-03-14 Nihon Kohden Corporation Lead wire attachment method, electrode, and spot welder
US6839594B2 (en) 2001-04-26 2005-01-04 Biocontrol Medical Ltd Actuation and control of limbs through motor nerve stimulation
US6684105B2 (en) 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
AU2002255248A1 (en) 2001-04-27 2002-11-11 Alexander Grinshpoon Diagnosis, treatment and research of mental disorders
US6810285B2 (en) * 2001-06-28 2004-10-26 Neuropace, Inc. Seizure sensing and detection using an implantable device
US20060241717A1 (en) 2001-08-30 2006-10-26 Whitehurst Todd K Treatment of movement disorders by extra dural motor cortex stimulation
WO2003026738A1 (en) 2001-09-28 2003-04-03 Northstar Neuroscience, Inc. Methods and apparatus for electrically stimulating cells implanted in the nervous system
AU2002334749A1 (en) 2001-09-28 2003-04-07 Northstar Neuroscience, Inc. Methods and implantable apparatus for electrical therapy
US7209788B2 (en) * 2001-10-29 2007-04-24 Duke University Closed loop brain machine interface
US6944497B2 (en) 2001-10-31 2005-09-13 Medtronic, Inc. System and method of treating stuttering by neuromodulation
US7050856B2 (en) 2002-01-11 2006-05-23 Medtronic, Inc. Variation of neural-stimulation parameters
US7110820B2 (en) 2002-02-05 2006-09-19 Tcheng Thomas K Responsive electrical stimulation for movement disorders
US7221981B2 (en) 2002-03-28 2007-05-22 Northstar Neuroscience, Inc. Electrode geometries for efficient neural stimulation
US7146222B2 (en) 2002-04-15 2006-12-05 Neurospace, Inc. Reinforced sensing and stimulation leads and use in detection systems
US7184840B2 (en) 2002-04-22 2007-02-27 Medtronic, Inc. Implantable lead with isolated contact coupling
US20050154426A1 (en) 2002-05-09 2005-07-14 Boveja Birinder R. Method and system for providing therapy for neuropsychiatric and neurological disorders utilizing transcranical magnetic stimulation and pulsed electrical vagus nerve(s) stimulation
US20060004423A1 (en) 2002-05-09 2006-01-05 Boveja Birinder R Methods and systems to provide therapy or alleviate symptoms of chronic headache, transformed migraine, and occipital neuralgia by providing rectangular and/or complex electrical pulses to occipital nerves
US20050182453A1 (en) 2002-05-24 2005-08-18 Whitehurst Todd K. Treatment of epilepsy by high frequency electrical stimulation and/or drug stimulation
EP1551497A2 (en) 2002-06-13 2005-07-13 Inc. Atlantic Medical Transcutaneous electrical nerve stimulation device and method using microcurrent
US7006859B1 (en) 2002-07-20 2006-02-28 Flint Hills Scientific, L.L.C. Unitized electrode with three-dimensional multi-site, multi-modal capabilities for detection and control of brain state changes
US6934580B1 (en) 2002-07-20 2005-08-23 Flint Hills Scientific, L.L.C. Stimulation methodologies and apparatus for control of brain states
US20040092809A1 (en) 2002-07-26 2004-05-13 Neurion Inc. Methods for measurement and analysis of brain activity
CA2397431A1 (en) 2002-08-09 2004-02-09 Andrew Lohbihler Method and apparatus for a wireless position sensing interface device employing spread spectrum technology of one or more radio transmitting devices
US7471974B2 (en) 2002-09-13 2008-12-30 Brainlab Ag Method for planning stimulation of hyper/hypometabolic cortical areas
US20050075679A1 (en) 2002-09-30 2005-04-07 Gliner Bradford E. Methods and apparatuses for treating neurological disorders by electrically stimulating cells implanted in the nervous system
US20040082847A1 (en) 2002-10-23 2004-04-29 Mcdermott Kathleen B. System and methods for identifying brain regions supporting language
US7236830B2 (en) 2002-12-10 2007-06-26 Northstar Neuroscience, Inc. Systems and methods for enhancing or optimizing neural stimulation therapy for treating symptoms of Parkinson's disease and/or other movement disorders
US7352833B2 (en) 2002-11-18 2008-04-01 Google Inc. Method and system for temporal autocorrelation filtering
US20050075680A1 (en) 2003-04-18 2005-04-07 Lowry David Warren Methods and systems for intracranial neurostimulation and/or sensing
US7302298B2 (en) 2002-11-27 2007-11-27 Northstar Neuroscience, Inc Methods and systems employing intracranial electrodes for neurostimulation and/or electroencephalography
US7565199B2 (en) 2002-12-09 2009-07-21 Advanced Neuromodulation Systems, Inc. Methods for treating and/or collecting information regarding neurological disorders, including language disorders
US6959215B2 (en) 2002-12-09 2005-10-25 Northstar Neuroscience, Inc. Methods for treating essential tremor
US7596408B2 (en) 2002-12-09 2009-09-29 Medtronic, Inc. Implantable medical device with anti-infection agent
US6937666B2 (en) 2002-12-20 2005-08-30 Bridgewave Communications, Inc. Wideband digital radio with transmit modulation cancellation
US6990377B2 (en) 2003-04-24 2006-01-24 Northstar Neuroscience, Inc. Systems and methods for facilitating and/or effectuating development, rehabilitation, restoration, and/or recovery of visual function through neural stimulation
US7065412B2 (en) 2003-04-25 2006-06-20 Medtronic, Inc. Implantable trial neurostimulation device
US7107104B2 (en) 2003-05-30 2006-09-12 Medtronic, Inc. Implantable cortical neural lead and method
US7684866B2 (en) 2003-08-01 2010-03-23 Advanced Neuromodulation Systems, Inc. Apparatus and methods for applying neural stimulation to a patient
US7187968B2 (en) 2003-10-23 2007-03-06 Duke University Apparatus for acquiring and transmitting neural signals and related methods
WO2005051480A2 (en) 2003-11-20 2005-06-09 Advanced Neuromodulation Systems, Inc. Electrical stimulation system, lead, and method providing reduced neuroplasticity effects
US8093205B2 (en) 2003-12-01 2012-01-10 Medtronic, Inc. Method for treating a stroke by implanting a first therapy delivery element in the CNS and a second therapy delivery element in a damaged tissue of the CNS to promote neurogenesis
US7107097B2 (en) 2004-01-14 2006-09-12 Northstar Neuroscience, Inc. Articulated neural electrode assembly
WO2005087314A1 (en) 2004-03-11 2005-09-22 Advanced Neuromodulation Systems, Inc. Brain stimulation system and method
EP1786510A4 (en) 2004-07-15 2009-12-02 Northstar Neuroscience Inc Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy
US20060020297A1 (en) 2004-07-20 2006-01-26 Gerber Martin T Neurostimulation system with distributed stimulators
US20050154425A1 (en) 2004-08-19 2005-07-14 Boveja Birinder R. Method and system to provide therapy for neuropsychiatric disorders and cognitive impairments using gradient magnetic pulses to the brain and pulsed electrical stimulation to vagus nerve(s)
WO2006047291A2 (en) 2004-10-21 2006-05-04 Advanced Neuromodulation Systems, Inc. Spinal cord stimulation to treat auditory dysfunction
US7565200B2 (en) 2004-11-12 2009-07-21 Advanced Neuromodulation Systems, Inc. Systems and methods for selecting stimulation sites and applying treatment, including treatment of symptoms of Parkinson's disease, other movement disorders, and/or drug side effects
US20060106430A1 (en) 2004-11-12 2006-05-18 Brad Fowler Electrode configurations for reducing invasiveness and/or enhancing neural stimulation efficacy, and associated methods
US20060173522A1 (en) 2005-01-31 2006-08-03 Medtronic, Inc. Anchoring of a medical device component adjacent a dura of the brain or spinal cord
US20070179558A1 (en) * 2006-01-30 2007-08-02 Gliner Bradford E Systems and methods for varying electromagnetic and adjunctive neural therapies

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5938688A (en) * 1997-10-22 1999-08-17 Cornell Research Foundation, Inc. Deep brain stimulation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1554011A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11848090B2 (en) 2019-05-24 2023-12-19 Axonics, Inc. Trainer for a neurostimulator programmer and associated methods of use with a neurostimulation system

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