WO2004026281A3 - Micro-reservoir osmotic release systems and microtube array device - Google Patents
Micro-reservoir osmotic release systems and microtube array device Download PDFInfo
- Publication number
- WO2004026281A3 WO2004026281A3 PCT/US2003/029924 US0329924W WO2004026281A3 WO 2004026281 A3 WO2004026281 A3 WO 2004026281A3 US 0329924 W US0329924 W US 0329924W WO 2004026281 A3 WO2004026281 A3 WO 2004026281A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- reservoir
- semi
- permeable membrane
- release formulation
- material layer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0097—Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0266—Shape memory materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/141—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor with capillaries for restricting fluid flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14526—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003278881A AU2003278881A1 (en) | 2002-09-23 | 2003-09-23 | Micro-reservoir osmotic release systems and microtube array device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41274602P | 2002-09-23 | 2002-09-23 | |
US60/412,746 | 2002-09-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004026281A2 WO2004026281A2 (en) | 2004-04-01 |
WO2004026281A3 true WO2004026281A3 (en) | 2004-08-19 |
Family
ID=32030928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/029924 WO2004026281A2 (en) | 2002-09-23 | 2003-09-23 | Micro-reservoir osmotic release systems and microtube array device |
Country Status (3)
Country | Link |
---|---|
US (1) | US7534241B2 (en) |
AU (1) | AU2003278881A1 (en) |
WO (1) | WO2004026281A2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7833266B2 (en) | 2007-11-28 | 2010-11-16 | Boston Scientific Scimed, Inc. | Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment |
US7951193B2 (en) | 2008-07-23 | 2011-05-31 | Boston Scientific Scimed, Inc. | Drug-eluting stent |
Families Citing this family (106)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1261427B1 (en) | 2000-03-02 | 2011-03-02 | Microchips, Inc. | Microfabricated devices and methods for storage and selective exposure of chemicals |
WO2002055058A2 (en) | 2001-01-09 | 2002-07-18 | Microchips, Inc. | Flexible microchip devices for ophthalmic and other applications |
WO2002099457A1 (en) * | 2001-05-31 | 2002-12-12 | Massachusetts Inst Technology | Microchip devices with improved reservoir opening |
ATE285756T1 (en) * | 2001-06-28 | 2005-01-15 | Microchips Inc | METHOD FOR HERMETIC SEALING MICROCHIP RESERVOIR DEVICES |
ATE458534T1 (en) * | 2002-10-04 | 2010-03-15 | Microchips Inc | MEDICAL DEVICE FOR CONTROLLED DRUG ADMINISTRATION AND CARDIAC MONITORING AND/OR HEART STIMULATION |
EP1638522B1 (en) * | 2003-04-25 | 2011-01-12 | Boston Scientific Scimed, Inc. | Solid drug formulation and device for storage and controlled delivery thereof |
DE10324324A1 (en) * | 2003-05-27 | 2004-12-16 | Bayer Ag | Polyamide molding compositions |
WO2005010240A2 (en) * | 2003-07-17 | 2005-02-03 | Microchips, Inc. | Low temperature methods for hermetically sealing reservoir devices |
US20050055014A1 (en) * | 2003-08-04 | 2005-03-10 | Coppeta Jonathan R. | Methods for accelerated release of material from a reservoir device |
US7104116B2 (en) * | 2003-09-25 | 2006-09-12 | Rockwell Automation Technologies, Inc. | Fluid sensor fixture for dynamic fluid testing |
US8095197B2 (en) * | 2003-11-03 | 2012-01-10 | Microchips, Inc. | Medical device for sensing glucose |
US8414489B2 (en) * | 2003-11-13 | 2013-04-09 | Medtronic Minimed, Inc. | Fabrication of multi-sensor arrays |
EP1691679B1 (en) * | 2003-11-13 | 2010-08-11 | Medtronic MiniMed, Inc. | Long term analyte sensor array |
AU2005327211A1 (en) * | 2004-06-01 | 2006-08-17 | Microchips, Inc. | Devices and methods for measuring and enhancing drug or analyte transport to/from medical implant |
US20070036835A1 (en) * | 2004-07-19 | 2007-02-15 | Microchips, Inc. | Hermetically Sealed Devices for Controlled Release or Exposure of Reservoir Contents |
US20080096923A1 (en) * | 2004-07-23 | 2008-04-24 | Aniz Girach | Methods For Diagnosing And Treating Diabetic Microvascular Complications |
WO2006015299A2 (en) * | 2004-07-30 | 2006-02-09 | Microchips, Inc. | Multi-reservoir device for transdermal drug delivery and sensing |
US7604628B2 (en) * | 2004-09-01 | 2009-10-20 | Microchips, Inc. | Multi-cap reservoir devices for controlled release or exposure of reservoir contents |
US20060046961A1 (en) * | 2004-09-02 | 2006-03-02 | Mckay William F | Controlled and directed local delivery of anti-inflammatory compositions |
US20060046960A1 (en) * | 2004-09-02 | 2006-03-02 | Mckay William F | Controlled and directed local delivery of anti-inflammatory compositions |
US20080038316A1 (en) * | 2004-10-01 | 2008-02-14 | Wong Vernon G | Conveniently implantable sustained release drug compositions |
EP3173072A1 (en) * | 2004-10-01 | 2017-05-31 | Ramscor, Inc. | Conveniently implantable sustained release drug compositions |
US8541413B2 (en) * | 2004-10-01 | 2013-09-24 | Ramscor, Inc. | Sustained release eye drop formulations |
US9993558B2 (en) | 2004-10-01 | 2018-06-12 | Ramscor, Inc. | Sustained release eye drop formulations |
US20060093646A1 (en) * | 2004-10-28 | 2006-05-04 | Cima Michael J | Orthopedic and dental implant devices providing controlled drug delivery |
SG157362A1 (en) * | 2004-11-04 | 2009-12-29 | Microchips Inc | Compression and cold weld sealing methods and devices |
US7413846B2 (en) * | 2004-11-15 | 2008-08-19 | Microchips, Inc. | Fabrication methods and structures for micro-reservoir devices |
CA2595457A1 (en) * | 2005-01-25 | 2006-08-03 | Microchips, Inc. | Control of drug release by transient modification of local microenvironments |
US20070016163A1 (en) * | 2005-06-28 | 2007-01-18 | Microchips, Inc. | Medical and dental implant devices for controlled drug delivery |
US20070025869A1 (en) * | 2005-07-15 | 2007-02-01 | Gordon John H | Fluid Delivery Device |
WO2007042961A2 (en) * | 2005-10-11 | 2007-04-19 | Koninklijke Philips Electronics N.V. | Device for controlled release of chemical molecules |
WO2007047279A1 (en) * | 2005-10-18 | 2007-04-26 | Richards Cynthia C | Dispenser having a first pump for insulin and a second pump for glucose or glucagon |
US8273071B2 (en) | 2006-01-18 | 2012-09-25 | The Invention Science Fund I, Llc | Remote controller for substance delivery system |
US9067047B2 (en) * | 2005-11-09 | 2015-06-30 | The Invention Science Fund I, Llc | Injectable controlled release fluid delivery system |
US8998884B2 (en) | 2005-11-09 | 2015-04-07 | The Invention Science Fund I, Llc | Remote controlled in situ reaction method |
US8992511B2 (en) * | 2005-11-09 | 2015-03-31 | The Invention Science Fund I, Llc | Acoustically controlled substance delivery device |
US20070106277A1 (en) * | 2005-11-09 | 2007-05-10 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Remote controller for substance delivery system |
US8083710B2 (en) | 2006-03-09 | 2011-12-27 | The Invention Science Fund I, Llc | Acoustically controlled substance delivery device |
GB2446096B (en) * | 2005-11-09 | 2012-01-11 | Searete Llc | Accoustically controlled reaction device |
US7942867B2 (en) * | 2005-11-09 | 2011-05-17 | The Invention Science Fund I, Llc | Remotely controlled substance delivery device |
US7699834B2 (en) * | 2005-11-09 | 2010-04-20 | Searete Llc | Method and system for control of osmotic pump device |
US8936590B2 (en) * | 2005-11-09 | 2015-01-20 | The Invention Science Fund I, Llc | Acoustically controlled reaction device |
US20070128240A1 (en) * | 2005-12-06 | 2007-06-07 | Peter Krulevitch | Compliant biocompatible packaging scheme based on NiTi shape memory alloys for implantable biomedical microsystems |
US8062287B2 (en) | 2005-12-22 | 2011-11-22 | Koninklijke Philips Electronics N V | Device for controlled release of chemical molecules |
US20080140057A1 (en) * | 2006-03-09 | 2008-06-12 | Searete Llc, A Limited Liability Corporation Of State Of The Delaware | Injectable controlled release fluid delivery system |
ES2493921T3 (en) * | 2006-03-14 | 2014-09-12 | University Of Southern California | MEMS device for the administration of therapeutic agents |
CN101432032A (en) * | 2006-04-28 | 2009-05-13 | 皇家飞利浦电子股份有限公司 | Osmotic pump with at least one chargeable material |
WO2008008845A2 (en) * | 2006-07-11 | 2008-01-17 | Microchips, Inc. | Multi-reservoir pump device for dialysis, biosensing, or delivery of substances |
EP2049080A2 (en) * | 2006-07-27 | 2009-04-22 | Koninklijke Philips Electronics N.V. | A drug delivery system with thermoswitchable membranes |
US20080033260A1 (en) * | 2006-08-03 | 2008-02-07 | Microchips, Inc. | Cardiac Biosensor Devices and Methods |
US20080147186A1 (en) * | 2006-12-14 | 2008-06-19 | Joshi Ashok V | Electrochemical Implant For Delivering Beneficial Agents |
WO2008134493A1 (en) * | 2007-04-25 | 2008-11-06 | Boston Scientific Scimed, Inc. | Medical devices for releasing therapeutic agent and methods of making the same |
GB2462779B (en) | 2007-05-25 | 2012-03-07 | Searete Llc | Injectable controlled release fluid delivery system |
US8092541B2 (en) | 2007-08-03 | 2012-01-10 | Warsaw Orthopedic, Inc. | Method of using an anti-growth matrix as a barrier for cell attachment and osteo-inductive factors |
EP2227286B1 (en) | 2007-11-28 | 2017-04-19 | Janisys Limited | A delivery device for administering an active substance to a subject |
US9308124B2 (en) | 2007-12-20 | 2016-04-12 | University Of Southern California | Apparatus and methods for delivering therapeutic agents |
EP2257250A2 (en) | 2008-01-29 | 2010-12-08 | Gilbert H. Kliman | Drug delivery devices, kits and methods therefor |
US20090259112A1 (en) * | 2008-04-09 | 2009-10-15 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Sensors |
US9333297B2 (en) | 2008-05-08 | 2016-05-10 | Minipumps, Llc | Drug-delivery pump with intelligent control |
WO2009137785A2 (en) | 2008-05-08 | 2009-11-12 | Replenish Pumps, Llc | Drug-delivery pumps and methods of manufacture |
EP2898911A1 (en) | 2008-05-08 | 2015-07-29 | MiniPumps, LLC | Implantable pumps and cannulas therefor |
DE102008002396A1 (en) * | 2008-06-12 | 2009-12-17 | Biotronik Vi Patent Ag | Implantable drug reservoir and device with an implantable drug reservoir |
JP2011525131A (en) | 2008-06-20 | 2011-09-15 | ボストン サイエンティフィック サイムド,インコーポレイテッド | Medical devices that utilize conductive polymers for the delivery of therapeutic agents |
EP2320962A2 (en) * | 2008-07-31 | 2011-05-18 | Boston Scientific Scimed, Inc. | Medical devices for therapeutic agent delivery |
CN102341133A (en) * | 2009-02-02 | 2012-02-01 | 麦德托尼克公司 | Antimicrobial accessory for implantable medical device |
EP3138603A1 (en) * | 2009-03-20 | 2017-03-08 | Incube Labs, Llc | Solid drug delivery apparatus, formulations and methods of use |
US8858983B2 (en) * | 2009-04-30 | 2014-10-14 | Medtronic, Inc. | Antioxidants and antimicrobial accessories including antioxidants |
CA2771584A1 (en) | 2009-08-18 | 2011-02-24 | Minipumps, Llc | Electrolytic drug-delivery pump with adaptive control |
US8696740B2 (en) | 2010-01-05 | 2014-04-15 | The Johns Hopkins University | Implantable pressure-actuated drug delivery systems and methods of manufacture and use |
US9046403B2 (en) * | 2010-02-01 | 2015-06-02 | Mallinckrodt Llc | Systems and methods for managing use of a medicament |
US8828246B2 (en) * | 2010-02-18 | 2014-09-09 | Anpac Bio-Medical Science Co., Ltd. | Method of fabricating micro-devices |
CN103108665A (en) | 2010-04-20 | 2013-05-15 | 迷你泵有限责任公司 | Electrolytically driven drug pump devices |
US8518440B2 (en) | 2010-12-21 | 2013-08-27 | Confluent Surgical, Inc. | Biodegradable osmotic pump implant for drug delivery |
US8911427B2 (en) | 2010-12-28 | 2014-12-16 | Medtronic, Inc. | Therapeutic agent reservoir delivery system |
WO2012121691A1 (en) * | 2011-03-04 | 2012-09-13 | Johns Hopkins University | Implantable pressure-actuated drug delivery systems and methods of manufacture and use |
EP2555039B1 (en) * | 2011-08-05 | 2017-08-23 | Samsung Electronics Co., Ltd. | Electrofluidic chromatophore (EFC) display apparatus |
CA2845778C (en) | 2011-08-25 | 2021-12-21 | Microchips, Inc. | Space-efficient containment devices and method of making same |
US10427153B2 (en) | 2011-08-25 | 2019-10-01 | Microchips Biotech, Inc. | Systems and methods for sealing a plurality of reservoirs of a microchip element with a sealing grid |
US20130090633A1 (en) * | 2011-10-07 | 2013-04-11 | University Of Southern California | Osmotic patch pump |
US20150005595A1 (en) | 2011-12-30 | 2015-01-01 | Kibur Medical, Inc. | Implantable devices and methods for evaluation of active agents |
CA2807716C (en) * | 2012-02-29 | 2019-06-11 | Johnson & Johnson Vision Care, Inc. | Punctal plug with energized containment array |
US8951303B2 (en) * | 2012-06-11 | 2015-02-10 | Ut-Battelle, Llc | Freeform fluidics |
CN104869888B (en) | 2012-12-21 | 2017-12-19 | 微芯片生物技术公司 | Implantable medical device for minimally invasive insertion |
CN104936648A (en) * | 2013-01-07 | 2015-09-23 | 林治远 | Metallic microneedles |
SG11201506675PA (en) | 2013-02-28 | 2015-09-29 | Microchips Biotech Inc | Implantable medical device for minimally-invasive insertion |
US20140330256A1 (en) * | 2013-05-02 | 2014-11-06 | Elwha Llc | Implantable Device for Manipulating Immune Cells |
US20140330257A1 (en) * | 2013-05-02 | 2014-11-06 | Elwha Llc | Implantable Device for Manipulating Immune Cells |
WO2014179398A1 (en) * | 2013-05-02 | 2014-11-06 | Elwha Llc | Implantable device for manipulating immune cells |
WO2015021031A1 (en) | 2013-08-05 | 2015-02-12 | Cam Med Llc | Conformable patch pump |
EP3113782B1 (en) * | 2014-03-06 | 2022-09-28 | TARIS Biomedical LLC | Drug delivery systems and methods for treatment of bladder cancer with gemcitabine |
JP6580593B2 (en) * | 2014-04-25 | 2019-09-25 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッドJohnson & Johnson Vision Care, Inc. | Method and ophthalmic device using an active agent release system |
US9764122B2 (en) | 2014-07-25 | 2017-09-19 | Warsaw Orthopedic, Inc. | Drug delivery device and methods having an occluding member |
US9775978B2 (en) | 2014-07-25 | 2017-10-03 | Warsaw Orthopedic, Inc. | Drug delivery device and methods having a retaining member |
US9937124B2 (en) | 2014-09-11 | 2018-04-10 | International Business Machines Corporation | Microchip substance delivery devices having low-power electromechanical release mechanisms |
US10881788B2 (en) | 2015-10-30 | 2021-01-05 | International Business Machines Corporation | Delivery device including reactive material for programmable discrete delivery of a substance |
US10076650B2 (en) | 2015-11-23 | 2018-09-18 | Warsaw Orthopedic, Inc. | Enhanced stylet for drug depot injector |
DE102016200211A1 (en) * | 2016-01-11 | 2017-07-13 | Raumedic Ag | Drug delivery device and drug delivery assembly |
USD802756S1 (en) | 2016-06-23 | 2017-11-14 | Warsaw Orthopedic, Inc. | Drug pellet cartridge |
US11268927B2 (en) | 2016-08-30 | 2022-03-08 | Analog Devices International Unlimited Company | Electrochemical sensor, and a method of forming an electrochemical sensor |
US10620151B2 (en) | 2016-08-30 | 2020-04-14 | Analog Devices Global | Electrochemical sensor, and a method of forming an electrochemical sensor |
US10847775B2 (en) * | 2016-10-14 | 2020-11-24 | Tiveni Mergeco, Inc. | Multi-layer contact plate configured to establish electrical bonds to battery cells in a battery module |
US10434261B2 (en) | 2016-11-08 | 2019-10-08 | Warsaw Orthopedic, Inc. | Drug pellet delivery system and method |
US11022579B2 (en) | 2018-02-05 | 2021-06-01 | Analog Devices International Unlimited Company | Retaining cap |
US11241562B2 (en) | 2018-03-13 | 2022-02-08 | Progenity, Inc. | Ingestible device with relatively large payload volume |
JP7167336B2 (en) | 2018-11-02 | 2022-11-08 | バイオナット ラブス リミテッド | Magneto-mechanical triggering of payload release from miniaturized devices |
KR20220091506A (en) * | 2019-11-01 | 2022-06-30 | 데어 엠비 아이엔씨. | Two-step microchip drug delivery device and method |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2911558A1 (en) * | 1979-03-23 | 1980-09-25 | Alza Corp | Liq. dispensing device - contains hydrophilic, water-insol. water-swellable polymer layer between compressible container and rigid casing |
GB2182559A (en) * | 1983-11-02 | 1987-05-20 | Alza Corp | Dispenser for thermo-responsive drugs |
US4874388A (en) * | 1987-06-25 | 1989-10-17 | Alza Corporation | Multi-layer delivery system |
WO2001012157A1 (en) * | 1999-08-18 | 2001-02-22 | Microchips, Inc. | Thermally-activated microchip chemical delivery devices |
WO2001064344A2 (en) * | 2000-03-02 | 2001-09-07 | Microchips, Inc. | Microfabricated devices for the storage and selective exposure of chemicals and devices |
WO2002099457A1 (en) * | 2001-05-31 | 2002-12-12 | Massachusetts Inst Technology | Microchip devices with improved reservoir opening |
Family Cites Families (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US976101A (en) * | 1910-06-09 | 1910-11-15 | Champion Ignition Co | Spark plug. |
US3762540A (en) * | 1970-05-19 | 1973-10-02 | Dentaire Ivoclar Ets | Receptacle having at least three chambers |
US3692027A (en) | 1971-04-23 | 1972-09-19 | Everett H Ellinwood Jr | Implanted medication dispensing device and method |
US4146029A (en) | 1974-04-23 | 1979-03-27 | Ellinwood Jr Everett H | Self-powered implanted programmable medication system and method |
US4003379A (en) | 1974-04-23 | 1977-01-18 | Ellinwood Jr Everett H | Apparatus and method for implanted self-powered medication dispensing |
US3952741A (en) | 1975-01-09 | 1976-04-27 | Bend Research Inc. | Controlled release delivery system by an osmotic bursting mechanism |
US4111202A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
US4360019A (en) | 1979-02-28 | 1982-11-23 | Andros Incorporated | Implantable infusion device |
DE2928477C3 (en) * | 1979-07-14 | 1982-04-15 | Battelle-Institut E.V., 6000 Frankfurt | Device for the release of substances at defined locations in the digestive tract |
US4312347A (en) * | 1980-02-25 | 1982-01-26 | Iowa State University Research Foundation, Inc. | Positive pressure drug releasing device |
JPS57163309A (en) | 1981-04-01 | 1982-10-07 | Olympus Optical Co Ltd | Capsule apparatus for medical use |
US4856188A (en) | 1984-10-12 | 1989-08-15 | Drug Delivery Systems Inc. | Method for making disposable and/or replenishable transdermal drug applicators |
US4781714A (en) | 1983-11-02 | 1988-11-01 | Alza Corporation | Dispenser for delivering thermo-responsive composition |
US4595583A (en) * | 1984-03-19 | 1986-06-17 | Alza Corporation | Delivery system controlled administration of beneficial agent to ruminants |
US4585652A (en) | 1984-11-19 | 1986-04-29 | Regents Of The University Of Minnesota | Electrochemical controlled release drug delivery system |
US5042975A (en) | 1986-07-25 | 1991-08-27 | Rutgers, The State University Of New Jersey | Iontotherapeutic device and process and iontotherapeutic unit dose |
US4731049A (en) | 1987-01-30 | 1988-03-15 | Ionics, Incorporated | Cell for electrically controlled transdermal drug delivery |
US5499979A (en) | 1987-06-25 | 1996-03-19 | Alza Corporation | Delivery system comprising kinetic forces |
US4957494A (en) | 1987-06-25 | 1990-09-18 | Alza Corporation | Multi-layer delivery system |
JP2561853B2 (en) * | 1988-01-28 | 1996-12-11 | 株式会社ジェイ・エム・エス | Shaped memory molded article and method of using the same |
US5252294A (en) | 1988-06-01 | 1993-10-12 | Messerschmitt-Bolkow-Blohm Gmbh | Micromechanical structure |
US5041107A (en) | 1989-10-06 | 1991-08-20 | Cardiac Pacemakers, Inc. | Electrically controllable, non-occluding, body implantable drug delivery system |
US5122128A (en) * | 1990-03-15 | 1992-06-16 | Alza Corporation | Orifice insert for a ruminal bolus |
US5196002A (en) | 1990-10-09 | 1993-03-23 | University Of Utah Research Foundation | Implantable drug delivery system with piston acutation |
US5167625A (en) | 1990-10-09 | 1992-12-01 | Sarcos Group | Multiple vesicle implantable drug delivery system |
US5254081A (en) | 1991-02-01 | 1993-10-19 | Empi, Inc. | Multiple site drug iontophoresis electronic device and method |
US5391164A (en) | 1991-05-03 | 1995-02-21 | Giampapa; Vincent C. | Subcutaneous implantable multiple-agent delivery system |
US5279607A (en) | 1991-05-30 | 1994-01-18 | The State University Of New York | Telemetry capsule and process |
US5401110A (en) * | 1991-07-15 | 1995-03-28 | Neeley; William E. | Custom label printer |
EP0604504A4 (en) | 1991-08-26 | 1995-05-17 | Univ Rutgers | Iontotherapeutic device and process. |
JP3456994B2 (en) | 1991-11-13 | 2003-10-14 | エラン コーポレーション ピーエルシー | Drug administration device |
US5429822A (en) | 1992-03-13 | 1995-07-04 | Cambridge Scientific, Inc. | Biodegradable bursting release system |
US5318557A (en) | 1992-07-13 | 1994-06-07 | Elan Medical Technologies Limited | Medication administering device |
US5368588A (en) | 1993-02-26 | 1994-11-29 | Bettinger; David S. | Parenteral fluid medication reservoir pump |
US5366454A (en) | 1993-03-17 | 1994-11-22 | La Corporation De L'ecole Polytechnique | Implantable medication dispensing device |
US5474527A (en) | 1993-03-29 | 1995-12-12 | Bettinger; David S. | Positive displacement transdermal system |
US5427585A (en) | 1993-03-29 | 1995-06-27 | Bettinger; David S. | On-demand iontophoretic system |
US5368704A (en) | 1993-08-06 | 1994-11-29 | Teknekron Corporation | Micro-electrochemical valves and method |
ES2176308T3 (en) | 1993-10-28 | 2002-12-01 | Houston Advanced Res Ct | POROUS MICROSTRUCTURE DEVICE THAT ALLOWS A FLOW. |
US5837276A (en) | 1994-09-02 | 1998-11-17 | Delab | Apparatus for the delivery of elongate solid drug compositions |
US5574313A (en) | 1994-10-17 | 1996-11-12 | Litten Systems, Inc. | Hermetically sealed microwave integrated circuit package with ground plane fused to package frame |
US6261584B1 (en) | 1996-02-02 | 2001-07-17 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
DE19610293C1 (en) | 1996-03-15 | 1997-07-31 | Fraunhofer Ges Forschung | Electronically-breakable microencapsulation system for sensitive materials |
US5824204A (en) | 1996-06-27 | 1998-10-20 | Ic Sensors, Inc. | Micromachined capillary electrophoresis device |
US5797898A (en) | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
JP4663824B2 (en) | 1996-12-31 | 2011-04-06 | ハイ スループット ジェノミクス インコーポレイテッド | Multiplexed molecular analyzer and method |
US5911737A (en) * | 1997-02-28 | 1999-06-15 | The Regents Of The University Of California | Microfabricated therapeutic actuators |
DE19716683C1 (en) | 1997-04-21 | 1998-06-04 | Fraunhofer Ges Forschung | Miniature encapsulation device for sensitive materials |
IL121286A0 (en) | 1997-07-11 | 1998-01-04 | Pets N People Ltd | Apparatus and methods for dispensing pet care substances |
US5961492A (en) | 1997-08-27 | 1999-10-05 | Science Incorporated | Fluid delivery device with temperature controlled energy source |
US6200293B1 (en) * | 1997-08-27 | 2001-03-13 | Science Incorporated | Fluid delivery device with temperature controlled energy source |
US6140740A (en) | 1997-12-30 | 2000-10-31 | Remon Medical Technologies, Ltd. | Piezoelectric transducer |
US6062461A (en) | 1998-06-03 | 2000-05-16 | Delphi Technologies, Inc. | Process for bonding micromachined wafers using solder |
US6183466B1 (en) * | 1998-08-21 | 2001-02-06 | Alza Corporation | Dosage form comprising a capsule |
US6112116A (en) | 1999-02-22 | 2000-08-29 | Cathco, Inc. | Implantable responsive system for sensing and treating acute myocardial infarction |
US6171850B1 (en) | 1999-03-08 | 2001-01-09 | Caliper Technologies Corp. | Integrated devices and systems for performing temperature controlled reactions and analyses |
JP4412874B2 (en) * | 1999-06-08 | 2010-02-10 | アルテア セラピューティクス コーポレイション | Apparatus for microporation of biological membranes using thin film tissue interface devices and methods therefor |
US6334859B1 (en) | 1999-07-26 | 2002-01-01 | Zuli Holdings Ltd. | Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments |
EP2308522A3 (en) | 1999-11-17 | 2012-02-29 | Boston Scientific Limited | Microfabricated devices for the delivery of molecules into a carrier fluid |
AU782639B2 (en) | 1999-12-10 | 2005-08-18 | Massachusetts Institute Of Technology | Microchip devices for delivery of molecules and methods of fabrication thereof |
US6730072B2 (en) | 2000-05-30 | 2004-05-04 | Massachusetts Institute Of Technology | Methods and devices for sealing microchip reservoir devices |
EP1339312B1 (en) | 2000-10-10 | 2006-01-04 | Microchips, Inc. | Microchip reservoir devices using wireless transmission of power and data |
WO2002030401A2 (en) | 2000-10-11 | 2002-04-18 | Microchips, Inc. | Microchip reservoir devices and facilitated corrosion of electrodes |
DE10063612C2 (en) | 2000-12-20 | 2002-11-07 | Fraunhofer Ges Forschung | Microsystem for controlling the delivery of active ingredients from an active ingredient reservoir as well as implant with microsystem |
WO2002055058A2 (en) | 2001-01-09 | 2002-07-18 | Microchips, Inc. | Flexible microchip devices for ophthalmic and other applications |
US6726678B1 (en) | 2001-02-22 | 2004-04-27 | Isurgical, Llc | Implantable reservoir and system for delivery of a therapeutic agent |
WO2002096389A1 (en) | 2001-05-30 | 2002-12-05 | Microchips, Inc. | Conformal coated microchip reservoir devices |
ATE285756T1 (en) | 2001-06-28 | 2005-01-15 | Microchips Inc | METHOD FOR HERMETIC SEALING MICROCHIP RESERVOIR DEVICES |
US6663615B1 (en) | 2001-09-04 | 2003-12-16 | The Ohio State University | Dual stage microvalve and method of use |
US7025323B2 (en) * | 2001-09-21 | 2006-04-11 | The Regents Of The University Of California | Low power integrated pumping and valving arrays for microfluidic systems |
CA2500453A1 (en) * | 2001-09-28 | 2003-04-03 | Biovalve Technologies, Inc. | Microneedle with membrane |
-
2003
- 2003-09-23 WO PCT/US2003/029924 patent/WO2004026281A2/en not_active Application Discontinuation
- 2003-09-23 US US10/668,573 patent/US7534241B2/en not_active Expired - Fee Related
- 2003-09-23 AU AU2003278881A patent/AU2003278881A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2911558A1 (en) * | 1979-03-23 | 1980-09-25 | Alza Corp | Liq. dispensing device - contains hydrophilic, water-insol. water-swellable polymer layer between compressible container and rigid casing |
GB2182559A (en) * | 1983-11-02 | 1987-05-20 | Alza Corp | Dispenser for thermo-responsive drugs |
US4874388A (en) * | 1987-06-25 | 1989-10-17 | Alza Corporation | Multi-layer delivery system |
WO2001012157A1 (en) * | 1999-08-18 | 2001-02-22 | Microchips, Inc. | Thermally-activated microchip chemical delivery devices |
WO2001064344A2 (en) * | 2000-03-02 | 2001-09-07 | Microchips, Inc. | Microfabricated devices for the storage and selective exposure of chemicals and devices |
WO2002099457A1 (en) * | 2001-05-31 | 2002-12-12 | Massachusetts Inst Technology | Microchip devices with improved reservoir opening |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7833266B2 (en) | 2007-11-28 | 2010-11-16 | Boston Scientific Scimed, Inc. | Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment |
US7951193B2 (en) | 2008-07-23 | 2011-05-31 | Boston Scientific Scimed, Inc. | Drug-eluting stent |
Also Published As
Publication number | Publication date |
---|---|
AU2003278881A1 (en) | 2004-04-08 |
US20040106914A1 (en) | 2004-06-03 |
WO2004026281A2 (en) | 2004-04-01 |
US7534241B2 (en) | 2009-05-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2004026281A3 (en) | Micro-reservoir osmotic release systems and microtube array device | |
WO2005016558A3 (en) | Methods for accelerated release of material from a reservoir device | |
HK1039054A1 (en) | Controlled release tablet comprising a hypoglycemic drug and an antihyperglycemic drug. | |
US7070590B1 (en) | Microchip drug delivery devices | |
WO2001091902A2 (en) | Methods and devices for sealing microchip reservoir devices | |
KR940703654A (en) | Osmotic Device with Delayed Activa-tion of Drug Delivery | |
WO2003024357A3 (en) | Microfabricated nanopore device for sustained release of therapeutic agent | |
DE69712063D1 (en) | MICROCHIP ARZNEISTOFFVERABREICHNUNGSSYSTEME | |
US6770183B1 (en) | Electrokinetic pump | |
KR102290262B1 (en) | Microcell systems for delivering active molecules | |
WO2002087976A3 (en) | Aerosol delivery system | |
ATE494885T1 (en) | SOLID MEDICINAL FORMULATION AND DEVICE FOR STORAGE AND CONTROLLED DELIVERY THEREOF | |
CN1222274C (en) | Expandable gastroretentive therapeutic system with prolonged stomach retention time | |
WO2009000216A3 (en) | A rupturing controlled release device comprising a subcoat | |
BR0107621A (en) | Combined osmotic pumping / diffusion drug delivery system | |
WO2002043800A3 (en) | Devices and methods for controlled delivery from a drug delivery device | |
WO2002055058A3 (en) | Flexible microchip devices for ophthalmic and other applications | |
WO2003024508A3 (en) | Gas pressure actuated microneedle arrays, and systems and methods relating to same | |
NO995313D0 (en) | Microarticles useful as ultrasonic contrast agents and for delivery of bloodstream drugs | |
WO2005039668A3 (en) | Implantable drug delivery device for sustained release of therapeutic agent | |
ATE256254T1 (en) | POLYMER VALVES | |
WO2002056939A3 (en) | Transmembrane transport apparatus and method | |
WO2004058425A3 (en) | Micro electromechanical systems for delivering high purity fluids in a chemical delivery system | |
JP2006500086A5 (en) | ||
JP6297495B2 (en) | Osmotic active vaginal delivery system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
122 | Ep: pct application non-entry in european phase | ||
NENP | Non-entry into the national phase |
Ref country code: JP |
|
WWW | Wipo information: withdrawn in national office |
Country of ref document: JP |