WO2004019256A3 - Measurement of bone density and bone structure from x-ray images for diagnosis of osteoporosis - Google Patents

Measurement of bone density and bone structure from x-ray images for diagnosis of osteoporosis Download PDF

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Publication number
WO2004019256A3
WO2004019256A3 PCT/US2003/025931 US0325931W WO2004019256A3 WO 2004019256 A3 WO2004019256 A3 WO 2004019256A3 US 0325931 W US0325931 W US 0325931W WO 2004019256 A3 WO2004019256 A3 WO 2004019256A3
Authority
WO
WIPO (PCT)
Prior art keywords
bone
bone structure
ray images
image
osteoporosis
Prior art date
Application number
PCT/US2003/025931
Other languages
French (fr)
Other versions
WO2004019256A2 (en
Inventor
Philipp Lang
Daniel Steines
Original Assignee
Imaging Therapeutics Inc
Philipp Lang
Daniel Steines
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imaging Therapeutics Inc, Philipp Lang, Daniel Steines filed Critical Imaging Therapeutics Inc
Priority to AU2003263926A priority Critical patent/AU2003263926A1/en
Priority to CA002495745A priority patent/CA2495745A1/en
Priority to EP03793126A priority patent/EP1530775A2/en
Publication of WO2004019256A2 publication Critical patent/WO2004019256A2/en
Publication of WO2004019256A3 publication Critical patent/WO2004019256A3/en

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Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/505—Clinical applications involving diagnosis of bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/58—Testing, adjusting or calibrating apparatus or devices for radiation diagnosis
    • A61B6/582—Calibration
    • A61B6/583—Calibration using calibration phantoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/44—Constructional features of apparatus for radiation diagnosis
    • A61B6/4423—Constructional features of apparatus for radiation diagnosis related to hygiene or sterilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/508—Clinical applications for non-human patients
    • A61B6/51—
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30008—Bone

Abstract

A method for the analysis of bone mineral density and/or bone structure from x-ray images using calibration phantoms which act as references in order to determine bone structure from an x-ray image. Regions of anatomical interest (ROI) in the image are identified. The method comprises: obtaining an x-ray image, analysing the image obtained using Hough transform skeleton operator, morphological operators, mean pixel intensity, variance of pixel intensity Fourier spectral analysis, fractal dimension or morphological parameters to derive quantitative information on bone structure.
PCT/US2003/025931 2002-08-20 2003-08-19 Measurement of bone density and bone structure from x-ray images for diagnosis of osteoporosis WO2004019256A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2003263926A AU2003263926A1 (en) 2002-08-20 2003-08-19 Measurement of bone density and bone structure from X-ray images for diagnosis of osteoporosis
CA002495745A CA2495745A1 (en) 2002-08-20 2003-08-19 Measurement of bone density and bone structure from x-ray images for diagnosis of osteoporosis
EP03793126A EP1530775A2 (en) 2002-08-20 2003-08-19 Methods and devices for analysis of x-ray images

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/225,083 2002-08-20
US10/225,083 US7660453B2 (en) 2000-10-11 2002-08-20 Methods and devices for analysis of x-ray images

Publications (2)

Publication Number Publication Date
WO2004019256A2 WO2004019256A2 (en) 2004-03-04
WO2004019256A3 true WO2004019256A3 (en) 2004-08-05

Family

ID=31946294

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/025931 WO2004019256A2 (en) 2002-08-20 2003-08-19 Measurement of bone density and bone structure from x-ray images for diagnosis of osteoporosis

Country Status (6)

Country Link
US (3) US7660453B2 (en)
EP (1) EP1530775A2 (en)
CN (1) CN1682236A (en)
AU (1) AU2003263926A1 (en)
CA (1) CA2495745A1 (en)
WO (1) WO2004019256A2 (en)

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