WO2004015107A3 - Further novel forms of interfering rna molecules - Google Patents

Further novel forms of interfering rna molecules Download PDF

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Publication number
WO2004015107A3
WO2004015107A3 PCT/EP2003/008666 EP0308666W WO2004015107A3 WO 2004015107 A3 WO2004015107 A3 WO 2004015107A3 EP 0308666 W EP0308666 W EP 0308666W WO 2004015107 A3 WO2004015107 A3 WO 2004015107A3
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WO
WIPO (PCT)
Prior art keywords
rna molecules
interfering rna
stretch
further novel
novel forms
Prior art date
Application number
PCT/EP2003/008666
Other languages
French (fr)
Other versions
WO2004015107A2 (en
Inventor
Klaus Giese
Joerg Kaufmann
Anke Klippel-Giese
Original Assignee
Atugen Ag
Klaus Giese
Joerg Kaufmann
Anke Klippel-Giese
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31720998&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2004015107(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP02017601A external-priority patent/EP1389637B1/en
Priority to CA2494930A priority Critical patent/CA2494930C/en
Priority to AU2003260370A priority patent/AU2003260370B2/en
Application filed by Atugen Ag, Klaus Giese, Joerg Kaufmann, Anke Klippel-Giese filed Critical Atugen Ag
Priority to JP2004526885A priority patent/JP4705370B2/en
Priority to KR1020057002008A priority patent/KR101201664B1/en
Priority to EP06027129.3A priority patent/EP1857547B2/en
Priority to IL16654603A priority patent/IL166546A0/en
Priority to EP03784183.0A priority patent/EP1527176B2/en
Priority to MXPA05001355A priority patent/MXPA05001355A/en
Priority to SI200330726T priority patent/SI1527176T1/en
Priority to EP10012263.9A priority patent/EP2258847B2/en
Priority to BRPI0313202A priority patent/BRPI0313202A8/en
Priority to EP17160954.8A priority patent/EP3222724B1/en
Priority to DE60310944.6T priority patent/DE60310944T3/en
Priority to DK03784183.0T priority patent/DK1527176T4/en
Priority to ES03784183.0T priority patent/ES2280826T5/en
Publication of WO2004015107A2 publication Critical patent/WO2004015107A2/en
Publication of WO2004015107A3 publication Critical patent/WO2004015107A3/en
Priority to ZA2005/00459A priority patent/ZA200500459B/en
Priority to IL16654605A priority patent/IL166546A/en
Priority to CY20071100439T priority patent/CY1106422T1/en
Priority to AU2008207337A priority patent/AU2008207337A1/en
Priority to CY181101252T priority patent/CY1120919T1/en

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    • C12N2320/51—Methods for regulating/modulating their activity modulating the chemical stability, e.g. nuclease-resistance

Abstract

The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double- stranded structure comprises a first strand and a second strand, whereby the first strand comprises a first stretch of contiguous nucleotides and whereby said first stretch is at least partially complementary to a target nucleic acid, and the second strand comprises a second stretch of contiguous nucleotides whereby said second stretch is at least partially identical to a target nucleic acid, and whereby the double stranded structure is blunt ended.
PCT/EP2003/008666 2002-08-05 2003-08-05 Further novel forms of interfering rna molecules WO2004015107A2 (en)

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AU2003260370A AU2003260370B2 (en) 2002-08-05 2003-08-05 Further novel forms of interfering RNA molecules
ES03784183.0T ES2280826T5 (en) 2002-08-05 2003-08-05 Additional new forms of interfering RNA molecules
BRPI0313202A BRPI0313202A8 (en) 2002-08-05 2003-08-05 ADDITIONAL WAYS TO INTERFERE WITH RNA MOLECULES
EP10012263.9A EP2258847B2 (en) 2002-08-05 2003-08-05 Futher novel forms of interfering RNA molecules
JP2004526885A JP4705370B2 (en) 2002-08-05 2003-08-05 Newer forms of interfering RNA molecules
KR1020057002008A KR101201664B1 (en) 2002-08-05 2003-08-05 Further novel forms of interfeing RNA molecules
EP06027129.3A EP1857547B2 (en) 2002-08-05 2003-08-05 Further novel forms of interfering RNA molecules
IL16654603A IL166546A0 (en) 2002-08-05 2003-08-05 Further novel forms of interfering ran molecules
EP03784183.0A EP1527176B2 (en) 2002-08-05 2003-08-05 Further novel forms of interfering rna molecules
MXPA05001355A MXPA05001355A (en) 2002-08-05 2003-08-05 Further novel forms of interfering rna molecules.
EP17160954.8A EP3222724B1 (en) 2002-08-05 2003-08-05 Further novel forms of interfering rna molecules
CA2494930A CA2494930C (en) 2002-08-05 2003-08-05 Modified forms of interfering rna molecules
DK03784183.0T DK1527176T4 (en) 2002-08-05 2003-08-05 ADDITIONAL NEW FORMS OF INTERFERRING RNA MOLECULES
SI200330726T SI1527176T1 (en) 2002-08-05 2003-08-05 Further novel forms of interfering rna molecules
DE60310944.6T DE60310944T3 (en) 2002-08-05 2003-08-05 OTHER NEW FORMS OF INTERFERING RNS MOLECULES
ZA2005/00459A ZA200500459B (en) 2002-08-05 2005-01-18 Further novel forms of interfering rna molecules
IL16654605A IL166546A (en) 2002-08-05 2005-01-27 Double stranded ribonucleic acid, composition containing same, use thereof in the preparation of medicaments and an in vitro method for inhibiting the expression of a target gene
CY20071100439T CY1106422T1 (en) 2002-08-05 2007-03-29 ADDITIONAL NEW FORMS OF INTERFERING RNA
AU2008207337A AU2008207337A1 (en) 2002-08-05 2008-08-15 Further novel forms of interfering RNA molecules
CY181101252T CY1120919T1 (en) 2002-08-05 2018-11-27 ADDITIONAL NEW FORMS OF INTERFERED RNA MOLECULES

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EP02017601.2 2002-08-05
EP02017601A EP1389637B1 (en) 2002-08-05 2002-08-05 Blunt-ended interfering RNA molecules
US40254102P 2002-08-12 2002-08-12
US60/402,541 2002-08-12
EP03008383 2003-04-10
EP03008383.6 2003-04-10

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KR (1) KR101201664B1 (en)
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AT (1) ATE350473T2 (en)
AU (2) AU2003260370B2 (en)
BR (1) BRPI0313202A8 (en)
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DK (4) DK1527176T4 (en)
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