WO2004011148A3 - Actuator for deformable valves in a microfluidic device, and method - Google Patents

Actuator for deformable valves in a microfluidic device, and method Download PDF

Info

Publication number
WO2004011148A3
WO2004011148A3 PCT/US2003/022459 US0322459W WO2004011148A3 WO 2004011148 A3 WO2004011148 A3 WO 2004011148A3 US 0322459 W US0322459 W US 0322459W WO 2004011148 A3 WO2004011148 A3 WO 2004011148A3
Authority
WO
WIPO (PCT)
Prior art keywords
microfluidic device
actuator
deformable valves
valves
deformable
Prior art date
Application number
PCT/US2003/022459
Other languages
French (fr)
Other versions
WO2004011148A2 (en
Inventor
David M Cox
Zbignew T Bryning
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/336,274 external-priority patent/US7198759B2/en
Priority claimed from US10/336,706 external-priority patent/US7214348B2/en
Application filed by Applera Corp filed Critical Applera Corp
Priority to AU2003252021A priority Critical patent/AU2003252021A1/en
Priority to CA002493687A priority patent/CA2493687A1/en
Priority to JP2005505603A priority patent/JP4377376B2/en
Priority to EP03771652A priority patent/EP1531936A4/en
Publication of WO2004011148A2 publication Critical patent/WO2004011148A2/en
Publication of WO2004011148A3 publication Critical patent/WO2004011148A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/08—Machines, pumps, or pumping installations having flexible working members having tubular flexible members
    • F04B43/082—Machines, pumps, or pumping installations having flexible working members having tubular flexible members the tubular flexible member being pressed against a wall by a number of elements, each having an alternating movement in a direction perpendicular to the axes of the tubular member and each having its own driving mechanism
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1223—Machines, pumps, or pumping installations having flexible working members having peristaltic action the actuating elements, e.g. rollers, moving in a straight line during squeezing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Abstract

A combination is provided that includes a microfluidic device (10) and a pivoting actuator (36). Methods of using the combination are also provided. The microfluidic device (10) can include valves (22) that can be opened by the pivoting actuator (36).
PCT/US2003/022459 2002-07-26 2003-07-16 Actuator for deformable valves in a microfluidic device, and method WO2004011148A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2003252021A AU2003252021A1 (en) 2002-07-26 2003-07-16 Actuator for deformable valves in a microfluidic device, and method
CA002493687A CA2493687A1 (en) 2002-07-26 2003-07-16 Actuator for deformable valves in a microfluidic device, and method
JP2005505603A JP4377376B2 (en) 2002-07-26 2003-07-16 Actuator and method for a deformable valve in a microfluidic device
EP03771652A EP1531936A4 (en) 2002-07-26 2003-07-16 Actuator for deformable valves in a microfluidic device, and method

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US39877702P 2002-07-26 2002-07-26
US39885102P 2002-07-26 2002-07-26
US39894602P 2002-07-26 2002-07-26
US60/398,777 2002-07-26
US60/398,946 2002-07-26
US60/398,851 2002-07-26
US10/336,706 2003-01-03
US10/336,274 US7198759B2 (en) 2002-07-26 2003-01-03 Microfluidic devices, methods, and systems
US10/336,274 2003-01-03
US10/336,706 US7214348B2 (en) 2002-07-26 2003-01-03 Microfluidic size-exclusion devices, systems, and methods
US10/403,640 US7201881B2 (en) 2002-07-26 2003-03-31 Actuator for deformable valves in a microfluidic device, and method
US10/403,640 2003-03-31

Publications (2)

Publication Number Publication Date
WO2004011148A2 WO2004011148A2 (en) 2004-02-05
WO2004011148A3 true WO2004011148A3 (en) 2004-03-18

Family

ID=31192532

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/022459 WO2004011148A2 (en) 2002-07-26 2003-07-16 Actuator for deformable valves in a microfluidic device, and method

Country Status (6)

Country Link
US (1) US7201881B2 (en)
EP (1) EP1531936A4 (en)
JP (1) JP4377376B2 (en)
AU (1) AU2003252021A1 (en)
CA (1) CA2493687A1 (en)
WO (1) WO2004011148A2 (en)

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US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device

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US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device

Also Published As

Publication number Publication date
US7201881B2 (en) 2007-04-10
EP1531936A2 (en) 2005-05-25
US20040131502A1 (en) 2004-07-08
CA2493687A1 (en) 2004-02-05
WO2004011148A2 (en) 2004-02-05
EP1531936A4 (en) 2005-09-07
JP4377376B2 (en) 2009-12-02
JP2006508817A (en) 2006-03-16
AU2003252021A1 (en) 2004-02-16

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