WO2004011132A3 - Closing blade for deformable valve in a microfluidic device, and method - Google Patents

Closing blade for deformable valve in a microfluidic device, and method Download PDF

Info

Publication number
WO2004011132A3
WO2004011132A3 PCT/US2003/022553 US0322553W WO2004011132A3 WO 2004011132 A3 WO2004011132 A3 WO 2004011132A3 US 0322553 W US0322553 W US 0322553W WO 2004011132 A3 WO2004011132 A3 WO 2004011132A3
Authority
WO
WIPO (PCT)
Prior art keywords
microfluidic device
blade
closing blade
deformable valve
deformable
Prior art date
Application number
PCT/US2003/022553
Other languages
French (fr)
Other versions
WO2004011132A2 (en
Inventor
David M Cox
Zbigniew T Bryning
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/336,274 external-priority patent/US7198759B2/en
Priority claimed from US10/336,706 external-priority patent/US7214348B2/en
Priority claimed from US10/403,640 external-priority patent/US7201881B2/en
Priority claimed from US10/403,652 external-priority patent/US7135147B2/en
Priority claimed from US10/426,587 external-priority patent/US6817373B2/en
Application filed by Applera Corp filed Critical Applera Corp
Priority to AU2003265285A priority Critical patent/AU2003265285A1/en
Priority to JP2005505604A priority patent/JP2006515232A/en
Priority to CA002493670A priority patent/CA2493670A1/en
Priority to EP03771660A priority patent/EP1539351A2/en
Publication of WO2004011132A2 publication Critical patent/WO2004011132A2/en
Publication of WO2004011132A3 publication Critical patent/WO2004011132A3/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L99/00—Subject matter not provided for in other groups of this subclass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology

Abstract

A microfluidic manipulation system is provided that includes a blade for manipulating deformable material and at least one movable support that is capable of moving the blade into contact with a microfluidic device including a deformable feature. When the microfluidic device is operatively held by a holder, a movable support can position the distal end of the blade relative to the microfluidic device and move the contact tip surface of the blade such that it deforms the deformable feature.
PCT/US2003/022553 2002-07-26 2003-07-18 Closing blade for deformable valve in a microfluidic device, and method WO2004011132A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2003265285A AU2003265285A1 (en) 2002-07-26 2003-07-18 Closing blade for deformable valve in a microfluidic device, and method
JP2005505604A JP2006515232A (en) 2002-07-26 2003-07-18 Closure blade and method for a deformable valve in a microfluidic device
CA002493670A CA2493670A1 (en) 2002-07-26 2003-07-18 Closing blade for deformable valve in a microfluidic device, and method
EP03771660A EP1539351A2 (en) 2002-07-26 2003-07-18 Closing blade for deformable valve in a microfluidic device, and method

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US39894602P 2002-07-26 2002-07-26
US39885102P 2002-07-26 2002-07-26
US39877702P 2002-07-26 2002-07-26
US60/398,777 2002-07-26
US60/398,851 2002-07-26
US60/398,946 2002-07-26
US10/336,274 US7198759B2 (en) 2002-07-26 2003-01-03 Microfluidic devices, methods, and systems
US10/336,274 2003-01-03
US10/336,706 US7214348B2 (en) 2002-07-26 2003-01-03 Microfluidic size-exclusion devices, systems, and methods
US10/336,706 2003-01-03
US10/403,652 2003-03-31
US10/403,640 US7201881B2 (en) 2002-07-26 2003-03-31 Actuator for deformable valves in a microfluidic device, and method
US10/403,652 US7135147B2 (en) 2002-07-26 2003-03-31 Closing blade for deformable valve in a microfluidic device and method
US10/403,640 2003-03-31
US10/426,587 US6817373B2 (en) 2002-07-26 2003-04-30 One-directional microball valve for a microfluidic device
US10/426,587 2003-04-30

Publications (2)

Publication Number Publication Date
WO2004011132A2 WO2004011132A2 (en) 2004-02-05
WO2004011132A3 true WO2004011132A3 (en) 2004-08-26

Family

ID=31192596

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/022553 WO2004011132A2 (en) 2002-07-26 2003-07-18 Closing blade for deformable valve in a microfluidic device, and method

Country Status (5)

Country Link
EP (1) EP1539351A2 (en)
JP (1) JP2006515232A (en)
AU (1) AU2003265285A1 (en)
CA (1) CA2493670A1 (en)
WO (1) WO2004011132A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627159B1 (en) 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
US7198759B2 (en) * 2002-07-26 2007-04-03 Applera Corporation Microfluidic devices, methods, and systems
CN111032229A (en) * 2017-08-25 2020-04-17 生物辐射实验室股份有限公司 Lateral flow pump casing

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358979A (en) * 1980-11-24 1982-11-16 Exxon Research & Engineering Co. Apparatus for cutting plastic film
US4851371A (en) * 1988-12-05 1989-07-25 Xerox Corporation Fabricating process for large array semiconductive devices
US6068751A (en) * 1995-12-18 2000-05-30 Neukermans; Armand P. Microfluidic valve and integrated microfluidic system

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5613200A (en) * 1979-07-12 1981-02-09 Seiko Instr & Electronics Marking method to molding part and its marking punch
JPH0592693A (en) * 1991-07-09 1993-04-16 Mitsubishi Materials Corp Thin precious metal composite plate and its manufacture and thin precious metal composite plate with pictorial characters
JPH06218919A (en) * 1993-01-25 1994-08-09 Seiko Epson Corp Ink jet type print head
SE501713C2 (en) * 1993-09-06 1995-05-02 Pharmacia Biosensor Ab Diaphragm-type valve, especially for liquid handling blocks with micro-flow channels
JP3389986B2 (en) * 1999-01-12 2003-03-24 セイコーエプソン株式会社 Inkjet recording head
JP2001070784A (en) * 1999-09-01 2001-03-21 Kawamura Inst Of Chem Res Extremely small chemical device with valve mechanism
JP2002192243A (en) * 2000-12-25 2002-07-10 Toshiba Corp Coining method and its machine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358979A (en) * 1980-11-24 1982-11-16 Exxon Research & Engineering Co. Apparatus for cutting plastic film
US4851371A (en) * 1988-12-05 1989-07-25 Xerox Corporation Fabricating process for large array semiconductive devices
US6068751A (en) * 1995-12-18 2000-05-30 Neukermans; Armand P. Microfluidic valve and integrated microfluidic system

Also Published As

Publication number Publication date
JP2006515232A (en) 2006-05-25
CA2493670A1 (en) 2004-02-05
WO2004011132A2 (en) 2004-02-05
AU2003265285A1 (en) 2004-02-16
EP1539351A2 (en) 2005-06-15

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