WO2003099230A3 - Electroprocessed collagen and tissue engineering - Google Patents

Electroprocessed collagen and tissue engineering Download PDF

Info

Publication number
WO2003099230A3
WO2003099230A3 PCT/US2003/016907 US0316907W WO03099230A3 WO 2003099230 A3 WO2003099230 A3 WO 2003099230A3 US 0316907 W US0316907 W US 0316907W WO 03099230 A3 WO03099230 A3 WO 03099230A3
Authority
WO
WIPO (PCT)
Prior art keywords
collagen
electroprocessed collagen
electroprocessed
tissue engineering
tissues
Prior art date
Application number
PCT/US2003/016907
Other languages
French (fr)
Other versions
WO2003099230A2 (en
Inventor
David G Simpson
Gary L Bowlin
Gary E Wnek
Peter J Stevens
Marcus E Carr
Jamil A Matthews
Saravanamoorthy Rajendran
Original Assignee
Univ Virginia Commonwealth
David G Simpson
Gary L Bowlin
Gary E Wnek
Peter J Stevens
Marcus E Carr
Jamil A Matthews
Saravanamoorthy Rajendran
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Virginia Commonwealth, David G Simpson, Gary L Bowlin, Gary E Wnek, Peter J Stevens, Marcus E Carr, Jamil A Matthews, Saravanamoorthy Rajendran filed Critical Univ Virginia Commonwealth
Priority to AU2003240939A priority Critical patent/AU2003240939A1/en
Publication of WO2003099230A2 publication Critical patent/WO2003099230A2/en
Publication of WO2003099230A3 publication Critical patent/WO2003099230A3/en

Links

Classifications

    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0015—Electro-spinning characterised by the initial state of the material
    • D01D5/003—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
    • D01D5/0038—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion the fibre formed by solvent evaporation, i.e. dry electro-spinning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00—Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

Abstract

The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
PCT/US2003/016907 2002-05-28 2003-05-28 Electroprocessed collagen and tissue engineering WO2003099230A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003240939A AU2003240939A1 (en) 2002-05-28 2003-05-28 Electroprocessed collagen and tissue engineering

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US38403502P 2002-05-28 2002-05-28
US60/384,035 2002-05-28
US38661202P 2002-06-06 2002-06-06
US60/386,612 2002-06-06
US39639902P 2002-07-15 2002-07-15
US60/396,399 2002-07-15
US40218902P 2002-08-08 2002-08-08
US60/402,189 2002-08-08

Publications (2)

Publication Number Publication Date
WO2003099230A2 WO2003099230A2 (en) 2003-12-04
WO2003099230A3 true WO2003099230A3 (en) 2004-06-10

Family

ID=29587853

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/016907 WO2003099230A2 (en) 2002-05-28 2003-05-28 Electroprocessed collagen and tissue engineering

Country Status (2)

Country Link
AU (1) AU2003240939A1 (en)
WO (1) WO2003099230A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200410714A (en) * 2002-08-07 2004-07-01 Smithkline Beecham Corp Electrospun amorphous pharmaceutical compositions
US7744651B2 (en) 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
US20040054414A1 (en) 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
JP2006515765A (en) 2002-11-15 2006-06-08 エスディージーアイ・ホールディングス・インコーポレーテッド Collagen-based materials and methods for treating synovial joints
CN100464015C (en) * 2006-02-24 2009-02-25 苏州大学 Machine for spinning nano-fiber for production of non-woven cloth
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
CN100441755C (en) * 2006-10-11 2008-12-10 东华大学 Method for preparing gelatin/chitosan blend for use in bionic extracellular matrix fiber stent
WO2008069760A1 (en) * 2006-12-05 2008-06-12 Nanyang Technological University Three-dimensional porous hybrid scaffold and manufacture thereof
US8557163B2 (en) 2006-12-05 2013-10-15 Nanyang Technological University Manufacturing three-dimensional scaffolds using cryogenic prototyping
CN102176905A (en) 2008-08-08 2011-09-07 巴斯夫欧洲公司 Fibrous surface structure containing active ingredients with controlled release of active ingredients, use thereof and method for the production thereof
EP2684562A1 (en) * 2008-08-08 2014-01-15 Basf Se Fibre layer with an active substance on the basis of bio-polymers, applications of same and method for their manufacture
WO2010132636A1 (en) 2009-05-13 2010-11-18 President And Fellows Of Harvard College Methods and devices for the fabrication of 3d polymeric fibers
US8951598B2 (en) 2010-05-07 2015-02-10 Empire Technology Development Llc Nanoscale collagen particles and membranes
US10519569B2 (en) 2013-02-13 2019-12-31 President And Fellows Of Harvard College Immersed rotary jet spinning devices (IRJS) and uses thereof
TWI690332B (en) 2018-09-20 2020-04-11 國立清華大學 Hybrid hydrogel and method of fabricating the same
CN116568877A (en) * 2020-12-11 2023-08-08 谢尔蒂斯股份公司 Reinforced heart valve leaflet

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3800792A (en) * 1972-04-17 1974-04-02 Johnson & Johnson Laminated collagen film dressing
WO1998003267A1 (en) * 1996-07-23 1998-01-29 Electrosols Ltd. A dispensing device and method for forming material
US6306424B1 (en) * 1999-06-30 2001-10-23 Ethicon, Inc. Foam composite for the repair or regeneration of tissue

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3800792A (en) * 1972-04-17 1974-04-02 Johnson & Johnson Laminated collagen film dressing
WO1998003267A1 (en) * 1996-07-23 1998-01-29 Electrosols Ltd. A dispensing device and method for forming material
US6306424B1 (en) * 1999-06-30 2001-10-23 Ethicon, Inc. Foam composite for the repair or regeneration of tissue

Also Published As

Publication number Publication date
WO2003099230A2 (en) 2003-12-04
AU2003240939A1 (en) 2003-12-12
AU2003240939A8 (en) 2003-12-12

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