WO2003091701A3 - Implantable biosensor from stratified nanostructured membranes - Google Patents

Implantable biosensor from stratified nanostructured membranes Download PDF

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Publication number
WO2003091701A3
WO2003091701A3 PCT/US2003/009525 US0309525W WO03091701A3 WO 2003091701 A3 WO2003091701 A3 WO 2003091701A3 US 0309525 W US0309525 W US 0309525W WO 03091701 A3 WO03091701 A3 WO 03091701A3
Authority
WO
WIPO (PCT)
Prior art keywords
biosensors
layer
monitored
stratified
field
Prior art date
Application number
PCT/US2003/009525
Other languages
French (fr)
Other versions
WO2003091701A2 (en
Inventor
Massoud Motamedi
James P Wicksted
Rinat Esenaliev
Original Assignee
Univ Texas
Kotov
Massoud Motamedi
James P Wicksted
Rinat Esenaliev
Oklahoma Coll Agri Mech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Kotov, Massoud Motamedi, James P Wicksted, Rinat Esenaliev, Oklahoma Coll Agri Mech filed Critical Univ Texas
Priority to AU2003253590A priority Critical patent/AU2003253590A1/en
Publication of WO2003091701A2 publication Critical patent/WO2003091701A2/en
Publication of WO2003091701A3 publication Critical patent/WO2003091701A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Abstract

A new class of biosensors and methods for making and using same are disclosed. The biosensors are multi-layered membrane composites, where at least one layer is prepared by the layer-by-layer process and at least one layer is responsive tochanges is a property of a biological system such as changes in the concentration of an atom, ion, molecule or molecular assembly. Because the biosensors are multi-layered, a single biosensor is capable monitor a number of different properties of a biological system simultaneously. The biosensors are monitored by systems that impinge an excitation waveform on the biosensors and analyze a reflected and/or a transmitted resultant waveform. Additionally, the biosensors can be associated with field activated electronic components so that implantable, self-contained analytical devices can be constructed and monitored by field generators, where data is transmitted to an analyzer after field activation.
PCT/US2003/009525 2002-03-29 2003-03-31 Implantable biosensor from stratified nanostructured membranes WO2003091701A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003253590A AU2003253590A1 (en) 2002-03-29 2003-03-31 Implantable biosensor from stratified nanostructured membranes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36892102P 2002-03-29 2002-03-29
US60/368,921 2002-03-29

Publications (2)

Publication Number Publication Date
WO2003091701A2 WO2003091701A2 (en) 2003-11-06
WO2003091701A3 true WO2003091701A3 (en) 2004-04-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/009525 WO2003091701A2 (en) 2002-03-29 2003-03-31 Implantable biosensor from stratified nanostructured membranes

Country Status (3)

Country Link
US (1) US7863038B2 (en)
AU (1) AU2003253590A1 (en)
WO (1) WO2003091701A2 (en)

Families Citing this family (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050033132A1 (en) * 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US7192450B2 (en) * 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
WO2003043934A1 (en) 2001-11-20 2003-05-30 Wm. Marsh Rice University Coated fullerenes, composites and dielectrics made therefrom
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US8364229B2 (en) * 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US9371559B2 (en) 2002-06-20 2016-06-21 The Regents Of The University Of California Compositions for detection and analysis of polynucleotides using light harvesting multichromophores
US10001475B2 (en) 2002-06-20 2018-06-19 The Regents Of The University Of California Light harvesting multichromophore compositions and methods of using the same
US7144950B2 (en) 2003-09-17 2006-12-05 The Regents Of The University Of California Conformationally flexible cationic conjugated polymers
CA2497152C (en) 2002-08-26 2016-06-07 The Regents Of The University Of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
US7253014B2 (en) * 2002-11-19 2007-08-07 William Marsh Rice University Fabrication of light emitting film coated fullerenes and their application for in-vivo light emission
AU2003304249A1 (en) 2002-11-19 2005-01-13 William Marsh Rice University Method for creating a functional interface between a nanoparticle, nanotube or nanowire, and a biological molecule or system
US7162308B2 (en) * 2002-11-26 2007-01-09 Wilson Greatbatch Technologies, Inc. Nanotube coatings for implantable electrodes
US7053783B2 (en) 2002-12-18 2006-05-30 Biovigilant Systems, Inc. Pathogen detector system and method
ATE448327T1 (en) * 2003-02-13 2009-11-15 Univ California METHODS AND COMPOSITIONS FOR DETECTING AND ANALYZING POLYNUCLEOTIDE BINDING-PROTEIN INTERACTIONS USING LIGHT-COLLECTING MULTICHROMOPHORES
US7056409B2 (en) 2003-04-17 2006-06-06 Nanosys, Inc. Structures, systems and methods for joining articles and materials and uses therefor
US7972616B2 (en) * 2003-04-17 2011-07-05 Nanosys, Inc. Medical device applications of nanostructured surfaces
US7579077B2 (en) * 2003-05-05 2009-08-25 Nanosys, Inc. Nanofiber surfaces for use in enhanced surface area applications
US20050221072A1 (en) * 2003-04-17 2005-10-06 Nanosys, Inc. Medical device applications of nanostructured surfaces
US20060122596A1 (en) * 2003-04-17 2006-06-08 Nanosys, Inc. Structures, systems and methods for joining articles and materials and uses therefor
US20050038498A1 (en) * 2003-04-17 2005-02-17 Nanosys, Inc. Medical device applications of nanostructured surfaces
JP4871726B2 (en) * 2003-04-28 2012-02-08 ナノシス・インク． Super lyophobic surface, its preparation and use
US7803574B2 (en) 2003-05-05 2010-09-28 Nanosys, Inc. Medical device applications of nanostructured surfaces
TWI427709B (en) * 2003-05-05 2014-02-21 Nanosys Inc Nanofiber surfaces for use in enhanced surface area applications
US7875293B2 (en) * 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
WO2007120442A2 (en) * 2003-07-25 2007-10-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7467003B2 (en) * 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7651596B2 (en) 2005-04-08 2010-01-26 Dexcom, Inc. Cellulosic-based interference domain for an analyte sensor
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US20070173709A1 (en) * 2005-04-08 2007-07-26 Petisce James R Membranes for an analyte sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US20080119703A1 (en) 2006-10-04 2008-05-22 Mark Brister Analyte sensor
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
EP1711790B1 (en) 2003-12-05 2010-09-08 DexCom, Inc. Calibration techniques for a continuous analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US20110039690A1 (en) 2004-02-02 2011-02-17 Nanosys, Inc. Porous substrates, articles, systems and compositions comprising nanofibers and methods of their use and production
US8025960B2 (en) 2004-02-02 2011-09-27 Nanosys, Inc. Porous substrates, articles, systems and compositions comprising nanofibers and methods of their use and production
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US7758892B1 (en) * 2004-05-20 2010-07-20 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US20060194198A1 (en) * 2004-06-29 2006-08-31 Carlo Licata Use of fibrous protein fibers for chemical sensing and radiation detection
US8696564B2 (en) * 2004-07-09 2014-04-15 Cardiac Pacemakers, Inc. Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth
US7654956B2 (en) 2004-07-13 2010-02-02 Dexcom, Inc. Transcutaneous analyte sensor
CN100595564C (en) * 2004-07-30 2010-03-24 百维吉伦特系统有限公司 Pathogen and particle detector system and method
US20060062982A1 (en) * 2004-09-17 2006-03-23 Massachusetts Institute Of Technology Carbon-polymer electrochemical systems and methods of fabricating them using layer-by-layer technology
US7811755B2 (en) * 2005-01-10 2010-10-12 The Regents Of The University Of California Methods and articles for strand-specific polynucleotide detection with cationic multichromophores
US7897684B2 (en) 2005-01-10 2011-03-01 The Regents Of The University Of California Conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays
US7666594B2 (en) * 2005-01-31 2010-02-23 The Regents Of The University Of California Methods for assaying a sample for an aggregant
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
US20060249381A1 (en) * 2005-05-05 2006-11-09 Petisce James R Cellulosic-based resistance domain for an analyte sensor
CN101223560B (en) * 2005-07-15 2012-12-12 百维吉伦特系统有限公司 Pathogen and particle detector system and method
US9640805B2 (en) * 2005-10-17 2017-05-02 GM Global Technology Operations LLC Coating process for fuel cell components
DE102005055398A1 (en) * 2005-11-17 2007-05-31 Wittenstein Ag Device for recording diagnostic values in the body
US7892596B2 (en) * 2005-12-19 2011-02-22 GM Global Technology Operations LLC Nanoparticle coating process for fuel cell components
JP4643484B2 (en) * 2006-03-29 2011-03-02 株式会社東芝 Screen transmission device and screen display method
US7809441B2 (en) * 2006-05-17 2010-10-05 Cardiac Pacemakers, Inc. Implantable medical device with chemical sensor and related methods
US9867530B2 (en) 2006-08-14 2018-01-16 Volcano Corporation Telescopic side port catheter device with imaging system and method for accessing side branch occlusions
US7831287B2 (en) * 2006-10-04 2010-11-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
CN101553579B (en) 2006-10-06 2016-01-20 赛里根有限公司 The fluorescent method amplified for directed biomarker signal and material
JP2010507798A (en) * 2006-10-24 2010-03-11 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Quantitative measurement of glycated hemoglobin
US8280470B2 (en) * 2006-11-03 2012-10-02 Volcano Corporation Analyte sensor method and apparatus
WO2008141271A1 (en) * 2007-05-10 2008-11-20 Newcyte, Inc. Artificial retinal implant
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US20080306434A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
WO2009009799A1 (en) 2007-07-12 2009-01-15 Volcano Corporation Catheter for in vivo imaging
US10219780B2 (en) 2007-07-12 2019-03-05 Volcano Corporation OCT-IVUS catheter for concurrent luminal imaging
US9596993B2 (en) 2007-07-12 2017-03-21 Volcano Corporation Automatic calibration systems and methods of use
US9452258B2 (en) 2007-10-09 2016-09-27 Dexcom, Inc. Integrated insulin delivery system with continuous glucose sensor
US8628976B2 (en) 2007-12-03 2014-01-14 Azbil BioVigilant, Inc. Method for the detection of biologic particle contamination
US8304595B2 (en) * 2007-12-06 2012-11-06 Nanosys, Inc. Resorbable nanoenhanced hemostatic structures and bandage materials
US8319002B2 (en) * 2007-12-06 2012-11-27 Nanosys, Inc. Nanostructure-enhanced platelet binding and hemostatic structures
WO2009105337A2 (en) * 2008-02-20 2009-08-27 Dexcom, Inc. Continuous medicament sensor system for in vivo use
CA2715628A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
JP5388309B2 (en) * 2008-03-28 2014-01-15 公益財団法人北九州産業学術推進機構 Composite thin film and atmosphere sensor and optical waveguide sensor including the same
WO2009129186A2 (en) * 2008-04-17 2009-10-22 Glumetrics, Inc. Sensor for percutaneous intravascular deployment without an indwelling cannula
US8540889B1 (en) 2008-11-19 2013-09-24 Nanosys, Inc. Methods of generating liquidphobic surfaces
US8794175B2 (en) * 2008-12-03 2014-08-05 The Regents Of The University Of Michigan Rolling contact layer-by-layer assembly
WO2010151807A1 (en) 2009-06-26 2010-12-29 Sirigen, Inc. Signal amplified biological detection with conjugated polymers
US8795783B2 (en) 2009-08-31 2014-08-05 The Regents Of The University Of Michigan Preparation of layer-by-layer materials and coatings from ionic liquids
EP4322238A2 (en) 2010-01-19 2024-02-14 Sirigen II Limited Novel reagents for directed biomarker signal amplification
KR101690535B1 (en) * 2010-10-06 2017-01-09 프로퓨사 인코퍼레이티드 Tissue-integrating sensors
US11141063B2 (en) 2010-12-23 2021-10-12 Philips Image Guided Therapy Corporation Integrated system architectures and methods of use
US11040140B2 (en) 2010-12-31 2021-06-22 Philips Image Guided Therapy Corporation Deep vein thrombosis therapeutic methods
ES2847578T3 (en) 2011-04-15 2021-08-03 Dexcom Inc Advanced analyte sensor calibration and error detection
EP2747650B1 (en) 2011-08-26 2023-04-05 Dexcom, Inc. Polymer membranes for continuous analyte sensors
WO2013033592A1 (en) 2011-08-31 2013-03-07 Volcano Corporation Optical-electrical rotary joint and methods of use
US10568586B2 (en) 2012-10-05 2020-02-25 Volcano Corporation Systems for indicating parameters in an imaging data set and methods of use
JP2015532536A (en) 2012-10-05 2015-11-09 デイビッド ウェルフォード， System and method for amplifying light
US9307926B2 (en) 2012-10-05 2016-04-12 Volcano Corporation Automatic stent detection
US10070827B2 (en) 2012-10-05 2018-09-11 Volcano Corporation Automatic image playback
US11272845B2 (en) 2012-10-05 2022-03-15 Philips Image Guided Therapy Corporation System and method for instant and automatic border detection
US9324141B2 (en) 2012-10-05 2016-04-26 Volcano Corporation Removal of A-scan streaking artifact
US9292918B2 (en) 2012-10-05 2016-03-22 Volcano Corporation Methods and systems for transforming luminal images
US9367965B2 (en) 2012-10-05 2016-06-14 Volcano Corporation Systems and methods for generating images of tissue
US9858668B2 (en) 2012-10-05 2018-01-02 Volcano Corporation Guidewire artifact removal in images
US9286673B2 (en) 2012-10-05 2016-03-15 Volcano Corporation Systems for correcting distortions in a medical image and methods of use thereof
US9840734B2 (en) 2012-10-22 2017-12-12 Raindance Technologies, Inc. Methods for analyzing DNA
JP6322210B2 (en) 2012-12-13 2018-05-09 ボルケーノ コーポレイション Devices, systems, and methods for targeted intubation
US10942022B2 (en) 2012-12-20 2021-03-09 Philips Image Guided Therapy Corporation Manual calibration of imaging system
WO2014099899A1 (en) 2012-12-20 2014-06-26 Jeremy Stigall Smooth transition catheters
EP2934282B1 (en) 2012-12-20 2020-04-29 Volcano Corporation Locating intravascular images
US10939826B2 (en) 2012-12-20 2021-03-09 Philips Image Guided Therapy Corporation Aspirating and removing biological material
JP2016504589A (en) 2012-12-20 2016-02-12 ナサニエル ジェイ． ケンプ， Optical coherence tomography system reconfigurable between different imaging modes
US11406498B2 (en) 2012-12-20 2022-08-09 Philips Image Guided Therapy Corporation Implant delivery system and implants
US10058284B2 (en) 2012-12-21 2018-08-28 Volcano Corporation Simultaneous imaging, monitoring, and therapy
US9612105B2 (en) 2012-12-21 2017-04-04 Volcano Corporation Polarization sensitive optical coherence tomography system
US10413317B2 (en) 2012-12-21 2019-09-17 Volcano Corporation System and method for catheter steering and operation
WO2014099760A1 (en) 2012-12-21 2014-06-26 Mai Jerome Ultrasound imaging with variable line density
US9383263B2 (en) 2012-12-21 2016-07-05 Volcano Corporation Systems and methods for narrowing a wavelength emission of light
CA2895769A1 (en) 2012-12-21 2014-06-26 Douglas Meyer Rotational ultrasound imaging catheter with extended catheter body telescope
JP2016508757A (en) 2012-12-21 2016-03-24 ジェイソン スペンサー， System and method for graphical processing of medical data
US9486143B2 (en) 2012-12-21 2016-11-08 Volcano Corporation Intravascular forward imaging device
JP2016501623A (en) 2012-12-21 2016-01-21 アンドリュー ハンコック， System and method for multipath processing of image signals
US10191220B2 (en) 2012-12-21 2019-01-29 Volcano Corporation Power-efficient optical circuit
WO2014103220A1 (en) * 2012-12-27 2014-07-03 パナソニック株式会社 Method for detecting test substance, and detection system
US9770172B2 (en) 2013-03-07 2017-09-26 Volcano Corporation Multimodal segmentation in intravascular images
US10226597B2 (en) 2013-03-07 2019-03-12 Volcano Corporation Guidewire with centering mechanism
US20140276923A1 (en) 2013-03-12 2014-09-18 Volcano Corporation Vibrating catheter and methods of use
CN105228518B (en) 2013-03-12 2018-10-09 火山公司 System and method for diagnosing coronal microvascular diseases
US9301687B2 (en) 2013-03-13 2016-04-05 Volcano Corporation System and method for OCT depth calibration
US11026591B2 (en) 2013-03-13 2021-06-08 Philips Image Guided Therapy Corporation Intravascular pressure sensor calibration
CN105120759B (en) 2013-03-13 2018-02-23 火山公司 System and method for producing image from rotation intravascular ultrasound equipment
CN105208947B (en) 2013-03-14 2018-10-12 火山公司 Filter with echoing characteristic
US10219887B2 (en) 2013-03-14 2019-03-05 Volcano Corporation Filters with echogenic characteristics
US10292677B2 (en) 2013-03-14 2019-05-21 Volcano Corporation Endoluminal filter having enhanced echogenic properties
DE102014112972A1 (en) * 2013-09-12 2015-03-12 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Measuring diaphragm for an optochemical or amperometric sensor
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
EP3206567A1 (en) 2014-10-13 2017-08-23 Glusense, Ltd. Analyte-sensing device
US10716500B2 (en) 2015-06-29 2020-07-21 Cardiac Pacemakers, Inc. Systems and methods for normalization of chemical sensor data based on fluid state changes
WO2017014252A1 (en) * 2015-07-22 2017-01-26 シャープ株式会社 Display device with touch panel, and method for manufacturing display device with touch panel
US10159434B1 (en) * 2015-11-30 2018-12-25 Verily Life Sciences Llc Systems and methods for optode imaging
WO2017100680A1 (en) * 2015-12-09 2017-06-15 The Texas A&M University System Implantable biosensors
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
US10871487B2 (en) 2016-04-20 2020-12-22 Glusense Ltd. FRET-based glucose-detection molecules
US9999899B2 (en) * 2016-11-01 2018-06-19 International Business Machines Corporation Controlled exposure of in-vivo sensors
CN108968976B (en) 2017-05-31 2022-09-13 心脏起搏器股份公司 Implantable medical device with chemical sensor
CN109381195B (en) 2017-08-10 2023-01-10 心脏起搏器股份公司 Systems and methods including electrolyte sensor fusion
CN109419515B (en) 2017-08-23 2023-03-24 心脏起搏器股份公司 Implantable chemical sensor with staged activation
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
CN111246797A (en) 2017-10-24 2020-06-05 德克斯康公司 Pre-attached analyte sensors
CN109864746B (en) 2017-12-01 2023-09-29 心脏起搏器股份公司 Multimode analyte sensor for medical devices
CN109864747B (en) 2017-12-05 2023-08-25 心脏起搏器股份公司 Multimode analyte sensor optoelectronic interface

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999035520A1 (en) * 1998-01-09 1999-07-15 Novartis Ag Coating of polymers
WO2000044507A1 (en) * 1999-01-28 2000-08-03 The Board Of Regents For Oklahoma State University Thin films of core-shell nanoparticles
WO2001057118A2 (en) * 2000-02-04 2001-08-09 Novartis Ag Process for coating a surface
WO2001072878A1 (en) * 2000-03-28 2001-10-04 The Board Of Regents For Oklahoma State University Assembly of free-standing films using a layer-by-layer process
WO2003001575A2 (en) * 2001-06-25 2003-01-03 The Board Of Regents For Oklahoma State University Preparation of graded semiconductor films by the layer-by-layer assembly of nanoparticles
WO2003075888A2 (en) * 2002-03-13 2003-09-18 Novartis Ag Materials containing multiple layers of vesicles

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703756A (en) * 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
US5628310A (en) * 1995-05-19 1997-05-13 Joseph R. Lakowicz Method and apparatus to perform trans-cutaneous analyte monitoring
CA2262018C (en) * 1996-07-29 2007-10-02 Nanosphere Llc Nanoparticles having oligonucleotides attached thereto and uses therefor
US6117643A (en) * 1997-11-25 2000-09-12 Ut Battelle, Llc Bioluminescent bioreporter integrated circuit
US6051437A (en) * 1998-05-04 2000-04-18 American Research Corporation Of Virginia Optical chemical sensor based on multilayer self-assembled thin film sensors for aquaculture process control
US6485703B1 (en) * 1998-07-31 2002-11-26 The Texas A&M University System Compositions and methods for analyte detection
US6605294B2 (en) * 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US6480282B1 (en) * 1999-05-06 2002-11-12 University Of Washington Capillary surface plasmon resonance sensors and multisensors
US7456025B2 (en) * 2001-08-28 2008-11-25 Porex Corporation Sintered polymer membrane for analyte detection device
WO2003035278A1 (en) * 2001-10-25 2003-05-01 Massachusetts Institute Of Technology Method of depositing polyelectrolyte multilayers and articles coated thereby
US20030152703A1 (en) * 2001-10-31 2003-08-14 Hammond Paula T. Production of chemically patterned surfaces using polymer-on-polymer stamping

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999035520A1 (en) * 1998-01-09 1999-07-15 Novartis Ag Coating of polymers
WO2000044507A1 (en) * 1999-01-28 2000-08-03 The Board Of Regents For Oklahoma State University Thin films of core-shell nanoparticles
WO2001057118A2 (en) * 2000-02-04 2001-08-09 Novartis Ag Process for coating a surface
WO2001072878A1 (en) * 2000-03-28 2001-10-04 The Board Of Regents For Oklahoma State University Assembly of free-standing films using a layer-by-layer process
WO2003001575A2 (en) * 2001-06-25 2003-01-03 The Board Of Regents For Oklahoma State University Preparation of graded semiconductor films by the layer-by-layer assembly of nanoparticles
WO2003075888A2 (en) * 2002-03-13 2003-09-18 Novartis Ag Materials containing multiple layers of vesicles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KOTOV N A: "Layer-by-layer assembled films of nanoparticles: materials perspectives and photonics and biophotonics applications", LEOS 2001. 14TH. ANNUAL MEETING OF THE IEEE LASERS & ELECTRO-OPTICS SOCIETY. SAN DIEGO, CA, NOV. 11 - 15, 2001, ANNUAL MEETING OF THE IEEE LASERS AND ELECTRO-OPTICS SOCIETY, NEW YORK, NY: IEEE, US, vol. 1 OF 2, 12 November 2001 (2001-11-12), pages 388 - 389, XP010566485, ISBN: 0-7803-7105-4 *
MAMEDOV A A ET AL: "FREE-STANDING LAYER-BY-LAYER ASSEMBLED FILMS OF MAGNETITE NANOPARTICLES", LANGMUIR, ACS, WASHINGTON, DC, US, vol. 16, no. 13, 27 June 2000 (2000-06-27), pages 5530 - 5533, XP001121097, ISSN: 0743-7463 *

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