WO2003090684A3 - Polymer compositions containing a macrocyclic triene compound - Google Patents

Polymer compositions containing a macrocyclic triene compound Download PDF

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Publication number
WO2003090684A3
WO2003090684A3 PCT/US2003/012746 US0312746W WO03090684A3 WO 2003090684 A3 WO2003090684 A3 WO 2003090684A3 US 0312746 W US0312746 W US 0312746W WO 03090684 A3 WO03090684 A3 WO 03090684A3
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WO
WIPO (PCT)
Prior art keywords
triene compound
macrocyclic triene
compositions containing
polymer compositions
polymer composition
Prior art date
Application number
PCT/US2003/012746
Other languages
French (fr)
Other versions
WO2003090684A2 (en
WO2003090684A8 (en
WO2003090684B1 (en
Inventor
John E Shulze
Ronald E Betts
Savage
Original Assignee
Sun Biomedical Ltd
John E Shulze
Ronald E Betts
Savage
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29268785&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2003090684(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sun Biomedical Ltd, John E Shulze, Ronald E Betts, Savage filed Critical Sun Biomedical Ltd
Priority to AU2003231757A priority Critical patent/AU2003231757B2/en
Priority to JP2003587323A priority patent/JP4315817B2/en
Publication of WO2003090684A2 publication Critical patent/WO2003090684A2/en
Publication of WO2003090684A3 publication Critical patent/WO2003090684A3/en
Publication of WO2003090684B1 publication Critical patent/WO2003090684B1/en
Publication of WO2003090684A8 publication Critical patent/WO2003090684A8/en

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    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
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    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
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    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • AHUMAN NECESSITIES
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61L2420/00Materials or methods for coatings medical devices
    • A61L2420/08Coatings comprising two or more layers

Abstract

A polymer composition for use in delivering a macrocyclic triene compound to a subject is described. The polymer composition is comprised of a polymer substrate containing as the macrocyclic triene compound a 40-0-hydroxy alkyl rapamycin derivative, where the alkyl group contains between 7-11 carbon atoms. The composition is useful for treating any condition responsive to rapamycin or everolimus, and methods of treatment using the polymer composition are described.
PCT/US2003/012746 2002-04-24 2003-04-24 Polymer compositions containing a macrocyclic triene compound WO2003090684A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003231757A AU2003231757B2 (en) 2002-04-24 2003-04-24 Polymer compositions containing a macrocyclic triene compound
JP2003587323A JP4315817B2 (en) 2002-04-24 2003-04-24 Polymer composition comprising macrocyclic triene compound

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/133,814 US6939376B2 (en) 2001-11-05 2002-04-24 Drug-delivery endovascular stent and method for treating restenosis
US10/133,814 2002-04-24

Publications (4)

Publication Number Publication Date
WO2003090684A2 WO2003090684A2 (en) 2003-11-06
WO2003090684A3 true WO2003090684A3 (en) 2004-02-26
WO2003090684B1 WO2003090684B1 (en) 2004-05-13
WO2003090684A8 WO2003090684A8 (en) 2004-12-16

Family

ID=29268785

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2003/012746 WO2003090684A2 (en) 2002-04-24 2003-04-24 Polymer compositions containing a macrocyclic triene compound
PCT/US2003/012750 WO2003090818A2 (en) 2002-04-24 2003-04-24 Drug-delivery endovascular stent and method for treating restenosis

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2003/012750 WO2003090818A2 (en) 2002-04-24 2003-04-24 Drug-delivery endovascular stent and method for treating restenosis

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Country Link
US (6) US6939376B2 (en)
EP (6) EP2113230A3 (en)
JP (6) JP2005523119A (en)
CN (3) CN1735402A (en)
AT (1) ATE451075T1 (en)
AU (3) AU2003231759B2 (en)
DE (1) DE60330455D1 (en)
ES (4) ES2514391T3 (en)
HK (3) HK1177882A1 (en)
WO (2) WO2003090684A2 (en)

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