WO2003090636A1 - Rf hyperthermia with needle electrodes enclosing a volume - Google Patents

Rf hyperthermia with needle electrodes enclosing a volume Download PDF

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Publication number
WO2003090636A1
WO2003090636A1 PCT/IT2003/000251 IT0300251W WO03090636A1 WO 2003090636 A1 WO2003090636 A1 WO 2003090636A1 IT 0300251 W IT0300251 W IT 0300251W WO 03090636 A1 WO03090636 A1 WO 03090636A1
Authority
WO
WIPO (PCT)
Prior art keywords
guide
guide needle
medical instrument
electrodes
instrument according
Prior art date
Application number
PCT/IT2003/000251
Other languages
French (fr)
Inventor
Luigi Venturelli
Original Assignee
Fogazzi Di Venturelli, Andrea & C. S.N.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fogazzi Di Venturelli, Andrea & C. S.N.C. filed Critical Fogazzi Di Venturelli, Andrea & C. S.N.C.
Priority to AU2003230218A priority Critical patent/AU2003230218A1/en
Publication of WO2003090636A1 publication Critical patent/WO2003090636A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00791—Temperature
    • A61B2018/00815—Temperature measured by a thermistor

Definitions

  • This invention concerns a medical instrument in the form of a needle treatment of tumours, in particular even if not exclusively for pulmonary tumours, using radio-frequency induced hyperthermia.
  • Instruments for the above mentioned use usually having a body in the shape of a tubular needle housing several electrodes which have proximal ends connected to a radio-frequency generator and active distal arc shaped ends are already well-known.
  • the electrodes can be moved between a passive position fully retracted into the tubular body, and an active forward position where the arch shaped distal ends protrude from the point of the tubular body.
  • the arch shaped ends of the electrodes when in the forward position are differently oriented but all face backwards, that is towards the proximal end of the tubular body.
  • Their functional efficacy is however limited in that the arch shaped distal ends tend either to move away from or to push the part to be treated away.
  • an instrument of this kind is without a guide wire and an independent thermocouple for reading the temperature in the area being treated.
  • the arch shaped active terminals of the electrodes face and converge forwards, and when retracted to move into the passive position, they have to be pulled back and housed in an axially moveable part positioned at the distal end of the body.
  • Such a moveable part however, besides being complicated to make, becomes, on the one hand, a further elongation of the body of the instrument when the electrodes are retracted and the needle is inserted into the patient's body, and on the other hand it has to be axially retracted into the needle to allow the electrodes to protrude. In this system as well there is no guide wire.
  • This invention is aimed at remedying the drawbacks and disadvantages known to exist in the medical instruments described above.
  • the radio-frequency active instrument structured in this way can be made to come into contact with the part to be treated without any difficulty, with the exclusion of the tendency to push it away as happens in the already known instruments, with the added possibility of having it attach itself to the part by means of a barb passing through the body of the instrument.
  • Fig. 1 shows a view, of one of the possible configurations of the invention, of a distal part of the instrument with electrodes protruding in an operating position and a thermistor;
  • Fig. 2 shows a longitudinal section of the instrument in Fig. 1 ;
  • Fig. 3 shows a cross-section as in Fig. 2, but with electrodes retracted
  • Fig. 4 shows a view of the head of the instrument in Fig. ;
  • Fig. 5 shows an enlarged cross-section in direction of the arrows A-A in Fig. 1
  • Fig. 6 shows a section as in Fig. 2, but in a variation of the configuration of the instrument; and Fig. 7 shows an enlarged cross-section in direction of the arrows B-B in
  • the instrument shown comprises of a guide body in the form of a hollow needle 11 , only a distal portion of which including the end point 11' being shown, for insertion into the patient's body until it reaches the part to be treated.
  • the body or guide needle 11 has a longitudinal hole 12 and at least a part of its length can be covered externally by an insulating sheath.
  • Two or more electrodes 13 (for example in the drawing there are four) stretching equidistant or non equidistant extend in the guide needle body from the proximal to the distal part of the body itself.
  • the electrodes 13 are each made up of a flexible filiform element made of a suitable material such as for example Nitinol ®, with a non-round cross- section, preferably flat or flattened for at least a part of their length.
  • the proximal ends of the electrodes 13 are connected, in the known way, to at least on connection, not shown, and by means of this to a radio- frequency generator connector.
  • the electrodes 13 are mainly rectilinear except for a distal segment which is pre-bent using a known technique, forming an arch or hook 14. Using the connector which joins them, the electrodes 13 can be moved longitudinally in the body of guide needle 11 between a retracted passive and a forward active position.
  • the electrodes 13 are fully retracted inside the body or guide needle, including their arch shaped or hooked 14 distal segment, which is obliged to adopt a rectilinear shape as shown in Fig. 3.
  • the distal segments 13 protrude from different sides of the body or guide needle 11, automatically adopting an arched or hook configuration 14 - Figs. 1 , 2.
  • the arched or hook shaped distal segments 14 are designed and oriented to extend forwards and converge beyond point 11' of the body or guide needle 11. They are helped to adopt this configuration by the particular cross-section of the elements forming the electrodes, chosen to prevent them from turning on an axis and to allow them to bend into an arch shape only in the required direction.
  • each electrode 13 is housed and guided in a respective guide device.
  • each electrode 13 passes longitudinally inside a corresponding guide tube 15 placed in the body or guide needle 11.
  • the guide tube 15 will have, for at least a part of its length, a round cross-section which is the same as the electrode it houses to prevent it from turning -Fig. 5.
  • the guide tubes 15 can be and remain fixed in the body of guide needle 11 whereas the electrodes are moved between the retracted and forward positions described above.
  • the guide tubes 15 can also be moved between a retracted and forward position, but independently from the electrodes 13 - Figs. 1 - 3. In this way the proximal ends of the guide tubes 15 can be attached to a respective grip, not shown, by means of which they can be moved forwards and backwards. Subsequently, starting from the retracted position - Fig.
  • the guide tubes 15 will be moved forward followed by the electrodes 13 until they adopt their active position where, as described above, the arched distal segments 14 will protrude and converge forwards of the point of the body or guide needle.
  • the distal parts of the guide tubes 15 are made to protrude from the body or guide needle - Figs. 1 and 2 - and if appropriately rounded or sharpened, they can become an anchoring means for the instrument to the part to be treated with the electrodes, facilitating approach to and the action of the latter on the part itself.
  • Figs. 1 and 2 - In a variation in design shown in Figs.
  • a grooved core 16 can be placed in the body or guide needle 11 in order to house and guide the electrodes 13, the core having at least the same number of longitudinal guide conduits 17 as there are electrodes 13.
  • the core 16 is stable and each of its conduits 17 is housed and moves an electrode 13 having the characteristics described above.
  • the cross-section of each guide conduit 17 is compatible with the cross-section of the electrode so as to prevent it from turning.
  • the distal end of each guide conduit 17 will also be shaped to facilitate retraction and better still protrusion of the distal end of the respective electrode in and out of the body or guide needle.
  • the electrodes 13, positioned and oriented as described above, are particularly efficient in that they can approach and treat the part using radio- frequency hyperthermia without the risk of pushing said part away.
  • a retractable wire 20 terminating in a barb 21 similar to a hook and which can be moved by hand or by a special spring loaded device can be placed in a special duct 18 as shown in Fig. 1 or in a longitudinal hole 19 provided in the core 16 as shown in Figs. 6 and 7.
  • the barb (hook) 21 comes into contact with the part to be treated to hold it and/or even to draw it closer to the electrodes in the active position.
  • the body or guide needle can house other components usually used such as a thermistor 22, also retractable, to read the temperature in the vicinity of the part requiring treatment.

Abstract

The invention concerns a medical instrument for radio-frequency induced hyperthermia treatment of tumors, made up of a body or guide needle (11) and a number of active electrodes (13) passing through said body or guide needle. Each electrode is made up of a flexible filiform element with a proximal part which can be connected to a radio-frequency generator and a pre-bent arch or hook shaped distal segment (14). The electrodes (13) can be moved longitudinally between a passive retracted position, where they are retracted into the body or guide needle, and an active forward position, where the respective arch or hook shaped distal segments (14) protrude from said body or guide needle. With the electrodes (13) forward in the active position, said arch or hook shaped distal segments (14) exit from the different sides of the body or guide needle and protrude and converge forwards beyond the distal end of said body or guide needle, thus encircling a given tissue volume for ablation.

Description

RF HYPERTHERMIA WITH NEEDLE ELECTRODES ENCLOSING A VOLUME
Field of the Invention This invention concerns a medical instrument in the form of a needle treatment of tumours, in particular even if not exclusively for pulmonary tumours, using radio-frequency induced hyperthermia. State of the Art
Instruments for the above mentioned use usually having a body in the shape of a tubular needle housing several electrodes which have proximal ends connected to a radio-frequency generator and active distal arc shaped ends are already well-known. The electrodes can be moved between a passive position fully retracted into the tubular body, and an active forward position where the arch shaped distal ends protrude from the point of the tubular body. According to a known system, the arch shaped ends of the electrodes when in the forward position are differently oriented but all face backwards, that is towards the proximal end of the tubular body. Their functional efficacy is however limited in that the arch shaped distal ends tend either to move away from or to push the part to be treated away. Furthermore, an instrument of this kind is without a guide wire and an independent thermocouple for reading the temperature in the area being treated.
According to another known embodiment, in an instrument similar to the type in question, the arch shaped active terminals of the electrodes face and converge forwards, and when retracted to move into the passive position, they have to be pulled back and housed in an axially moveable part positioned at the distal end of the body. Such a moveable part however, besides being complicated to make, becomes, on the one hand, a further elongation of the body of the instrument when the electrodes are retracted and the needle is inserted into the patient's body, and on the other hand it has to be axially retracted into the needle to allow the electrodes to protrude. In this system as well there is no guide wire. Objectives and Summary of the Invention
This invention is aimed at remedying the drawbacks and disadvantages known to exist in the medical instruments described above.
It is in fact one objective of this invention to provide an instrument in the form of a needle with several active electrodes, improved in design and functionally more practical and efficient, for treating tumours, in particular lung tumours, using radio-frequency induced hyperthermia. Another object of the invention is to provide an instrument in the form of a needle with radio-frequency active electrodes, where the arched ends of the electrodes face and converge forwards, but can be retracted into the body of the needle, excluding the presence of a moveable distal part.
These objects are achieved in a medical instrument with several active electrodes in compliance with at least claim 1.
The radio-frequency active instrument structured in this way can be made to come into contact with the part to be treated without any difficulty, with the exclusion of the tendency to push it away as happens in the already known instruments, with the added possibility of having it attach itself to the part by means of a barb passing through the body of the instrument. Brief Description of the Drawings
The invention will however be illustrated more in detail in the following description made in reference to the enclosed indicative and non-limiting drawings, in which: Fig. 1 shows a view, of one of the possible configurations of the invention, of a distal part of the instrument with electrodes protruding in an operating position and a thermistor;
Fig. 2 shows a longitudinal section of the instrument in Fig. 1 ;
Fig. 3 shows a cross-section as in Fig. 2, but with electrodes retracted; Fig. 4 shows a view of the head of the instrument in Fig. ;
Fig. 5 shows an enlarged cross-section in direction of the arrows A-A in Fig. 1
Fig. 6 shows a section as in Fig. 2, but in a variation of the configuration of the instrument; and Fig. 7 shows an enlarged cross-section in direction of the arrows B-B in
Fig. 6 Detailed Description of the Invention
The instrument shown comprises of a guide body in the form of a hollow needle 11 , only a distal portion of which including the end point 11' being shown, for insertion into the patient's body until it reaches the part to be treated.
The body or guide needle 11 has a longitudinal hole 12 and at least a part of its length can be covered externally by an insulating sheath.
Two or more electrodes 13 (for example in the drawing there are four) stretching equidistant or non equidistant extend in the guide needle body from the proximal to the distal part of the body itself.
The electrodes 13 are each made up of a flexible filiform element made of a suitable material such as for example Nitinol ®, with a non-round cross- section, preferably flat or flattened for at least a part of their length. The proximal ends of the electrodes 13 are connected, in the known way, to at least on connection, not shown, and by means of this to a radio- frequency generator connector. The electrodes 13 are mainly rectilinear except for a distal segment which is pre-bent using a known technique, forming an arch or hook 14. Using the connector which joins them, the electrodes 13 can be moved longitudinally in the body of guide needle 11 between a retracted passive and a forward active position. In the retracted position the electrodes 13 are fully retracted inside the body or guide needle, including their arch shaped or hooked 14 distal segment, which is obliged to adopt a rectilinear shape as shown in Fig. 3. In the forward position, the distal segments 13 protrude from different sides of the body or guide needle 11, automatically adopting an arched or hook configuration 14 - Figs. 1 , 2.
The arched or hook shaped distal segments 14 are designed and oriented to extend forwards and converge beyond point 11' of the body or guide needle 11. They are helped to adopt this configuration by the particular cross-section of the elements forming the electrodes, chosen to prevent them from turning on an axis and to allow them to bend into an arch shape only in the required direction.
Furthermore, in order to allow correct placement of the electrodes inside the body or guide needle 11 , including correct sliding and orientation , each electrode 13 is housed and guided in a respective guide device.
According to one configuration in fact, each electrode 13 passes longitudinally inside a corresponding guide tube 15 placed in the body or guide needle 11. The guide tube 15 will have, for at least a part of its length, a round cross-section which is the same as the electrode it houses to prevent it from turning -Fig. 5.
The guide tubes 15 can be and remain fixed in the body of guide needle 11 whereas the electrodes are moved between the retracted and forward positions described above. As an alternative, the guide tubes 15 can also be moved between a retracted and forward position, but independently from the electrodes 13 - Figs. 1 - 3. In this way the proximal ends of the guide tubes 15 can be attached to a respective grip, not shown, by means of which they can be moved forwards and backwards. Subsequently, starting from the retracted position - Fig. 3 - where the guide tubes and electrodes are fully retracted into the body 11 , first the guide tubes 15 will be moved forward followed by the electrodes 13 until they adopt their active position where, as described above, the arched distal segments 14 will protrude and converge forwards of the point of the body or guide needle. In particular, when they are in the forward position, the distal parts of the guide tubes 15 are made to protrude from the body or guide needle - Figs. 1 and 2 - and if appropriately rounded or sharpened, they can become an anchoring means for the instrument to the part to be treated with the electrodes, facilitating approach to and the action of the latter on the part itself. In a variation in design shown in Figs. 6 and 7, a grooved core 16 can be placed in the body or guide needle 11 in order to house and guide the electrodes 13, the core having at least the same number of longitudinal guide conduits 17 as there are electrodes 13. The core 16 is stable and each of its conduits 17 is housed and moves an electrode 13 having the characteristics described above. The cross-section of each guide conduit 17 is compatible with the cross-section of the electrode so as to prevent it from turning. The distal end of each guide conduit 17 will also be shaped to facilitate retraction and better still protrusion of the distal end of the respective electrode in and out of the body or guide needle. The electrodes 13, positioned and oriented as described above, are particularly efficient in that they can approach and treat the part using radio- frequency hyperthermia without the risk of pushing said part away.
Furthermore, a retractable wire 20 terminating in a barb 21 similar to a hook and which can be moved by hand or by a special spring loaded device can be placed in a special duct 18 as shown in Fig. 1 or in a longitudinal hole 19 provided in the core 16 as shown in Figs. 6 and 7. When the wire 20 is in a forward position protruding beyond point 11' of the body or guide needle, the barb (hook) 21 comes into contact with the part to be treated to hold it and/or even to draw it closer to the electrodes in the active position. Worthy of note is the fact that the body or guide needle can house other components usually used such as a thermistor 22, also retractable, to read the temperature in the vicinity of the part requiring treatment.

Claims

C L A I M S 1. Medical instrument for radio-frequency induced hyperthermia treatment of tumours, comprising a body or guide needle (11) and a number of active electrodes (13) passing through said body or guide needle from a proximal end to a distal end, where each electrode is made up of a flexible filiform element with a proximal part connectedable to a radio-frequency generator and a pre-bent arch or hook shaped (14)distal segment, and where the electrodes (13) are movable longitudinally between a passive retracted position, in which they are retracted into the body or guide needle, and an active forward position, in which the respective arch or hook shaped distal segments (14) protrude from said body or guide needle, characterised by the fact that, with the electrodes (13) forward in the active position, said arch or hook shaped distal segments (14) exit from the different sides of the body or guide needle and protrude and converge forwards beyond the distal end of said body or guide needle.
2. Instrument in compliance with claim 1 , wherein each filiform element making up an active electrode (13, 14) has a flat section or at least a part which is flattened.
3. Medical instrument according to claims 1 and 2, wherein the active electrodes (13, 14) are constrained and movable longitudinally in the body or guide needle (11 ) without turning.
4. Medical instrument according to claim 3, wherein the active electrodes (13,14) are each lodged in a respective guide tube (15) placed in the body or guide needle (11), the guide tube having at least a part with a cross-section the same size as that of the filiform element forming the electrode.
5. Medical instrument according to claim 4, wherein the guide tubes
(15) are stable and the active electrodes (13, 14) slide in said guide tubes between said retracted and forward positions.
6. Medical instrument according to claim 5, wherein the guide tubes (15) are moveable longitudinally in said body or guide needle (15), and the active electrodes (13, 14) can slide in said guide tubes, the movement of the guide tubes and active electrodes being independent and possible at different times.
7. Medical instrument according to claim 6, wherein said guide tubes (15) are moveable between a retracted position in the body or guide needle (11) and a forward position protruding less from the different sides of said body or guide needle than the distal arch or hook shaped segments (14) of the active electrodes (13) when the latter are in the forward position.
8. Medical instrument according to claim 7, wherein the guide tubes (15) of the active electrodes (13, 14) have a rounded or pointed distal end.
9. Medical instrument according to claim 3, wherein the body or guide needle (11) houses a grooved core (16) having a number of longitudinal guide ducts (17) and wherein the active electrodes (13, 14) are housed and slide individually in said guide ducts and are moveable lengthwise between said retracted and forward positions.
10. Medical instrument according to claim 9, wherein each guide duct (17) has a cross-section compatible with the respective active electrode (13, 14) to prevent the latter from turning.
11. Medical instrument according to any of the previous claims, including also a retractable wire (20) stretching lengthwise in the body or guide needle (11) having a distal end in the shape of an anchoring hook (21) capable of penetrating into the part to be treated.
12. Medical instrument according to claim 11 , wherein said retractable wire (20) is guided in the respective guide tube or a hole provided in the grooved core (16) and which can be moved manually or by means of a spring- loaded plunger device between a retracted and a forward position.
13. Medical instrument according to any of the previous claims which also includes a means of reading the temperature which passes through the body or guide needle.
PCT/IT2003/000251 2002-04-23 2003-04-18 Rf hyperthermia with needle electrodes enclosing a volume WO2003090636A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003230218A AU2003230218A1 (en) 2002-04-23 2003-04-18 Rf hyperthermia with needle electrodes enclosing a volume

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITBS20020042 ITBS20020042A1 (en) 2002-04-23 2002-04-23 NEEDLE ELECTRODE PERFECTED FOR A TREATMENT OF TUMORS BY RADIOFREQUENCY-INDUCED HYPERTHERMIA
ITBS2002A000042 2002-04-23

Publications (1)

Publication Number Publication Date
WO2003090636A1 true WO2003090636A1 (en) 2003-11-06

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PCT/IT2003/000251 WO2003090636A1 (en) 2002-04-23 2003-04-18 Rf hyperthermia with needle electrodes enclosing a volume

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AU (1) AU2003230218A1 (en)
IT (1) ITBS20020042A1 (en)
WO (1) WO2003090636A1 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2862521A1 (en) * 2003-11-24 2005-05-27 Juan Carlos Chachques Catheter for injecting therapeutic or diagnostic agent into organ, e.g. heart, includes fixing mechanisms for fixing the catheter to the organ and having suction cup mounted so that it may be retracted into lumen of exterior tube
EP1898822A2 (en) * 2005-07-01 2008-03-19 Halt Medical, Inc. Anchored rf ablation device for the destruction of tissue masses
US8202271B2 (en) 2006-01-24 2012-06-19 Covidien Ag Dual synchro-resonant electrosurgical apparatus with bi-directional magnetic coupling
CN108056814A (en) * 2018-02-05 2018-05-22 青岛亿嘉诺日化有限公司 It is grouped adjustable radio frequency ablation needle
US10828088B2 (en) 2005-07-01 2020-11-10 Acessa Health Inc. Radio frequency ablation device for the destruction of tissue masses
WO2022141769A1 (en) * 2020-12-31 2022-07-07 杭州堃博生物科技有限公司 Radio-frequency ablation catheter and radio-frequency ablation system
EP4085858A4 (en) * 2019-12-31 2024-02-21 Hangzhou Broncus Medical Co Ltd Detection mechanism, radio-frequency ablation catheter and radio-frequency ablation system

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WO2000013603A1 (en) * 1998-09-04 2000-03-16 Rita Medical Systems, Inc. Electrosurgical device for necrosis induction
US6212433B1 (en) * 1998-07-28 2001-04-03 Radiotherapeutics Corporation Method for treating tumors near the surface of an organ
WO2002022032A1 (en) * 2000-09-15 2002-03-21 Radiotherapeutics Corporation Methods and systems for focused bipolar tissue ablation

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US6212433B1 (en) * 1998-07-28 2001-04-03 Radiotherapeutics Corporation Method for treating tumors near the surface of an organ
WO2000013603A1 (en) * 1998-09-04 2000-03-16 Rita Medical Systems, Inc. Electrosurgical device for necrosis induction
WO2002022032A1 (en) * 2000-09-15 2002-03-21 Radiotherapeutics Corporation Methods and systems for focused bipolar tissue ablation

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2862521A1 (en) * 2003-11-24 2005-05-27 Juan Carlos Chachques Catheter for injecting therapeutic or diagnostic agent into organ, e.g. heart, includes fixing mechanisms for fixing the catheter to the organ and having suction cup mounted so that it may be retracted into lumen of exterior tube
EP1535580A1 (en) * 2003-11-24 2005-06-01 Chachques, Juan C. Diagnostic and injection catheter, in particular for an application in cardiology
US7842015B2 (en) 2003-11-24 2010-11-30 Juan Carlos Chachques Diagnostic and injection catheter, in particular for an application in cardiology
EP1898822A2 (en) * 2005-07-01 2008-03-19 Halt Medical, Inc. Anchored rf ablation device for the destruction of tissue masses
EP1898822A4 (en) * 2005-07-01 2012-12-26 Halt Medical Inc Anchored rf ablation device for the destruction of tissue masses
US10828088B2 (en) 2005-07-01 2020-11-10 Acessa Health Inc. Radio frequency ablation device for the destruction of tissue masses
US8202271B2 (en) 2006-01-24 2012-06-19 Covidien Ag Dual synchro-resonant electrosurgical apparatus with bi-directional magnetic coupling
CN108056814A (en) * 2018-02-05 2018-05-22 青岛亿嘉诺日化有限公司 It is grouped adjustable radio frequency ablation needle
CN108056814B (en) * 2018-02-05 2024-03-29 陕西菲尼科斯医疗科技有限公司 Grouping-adjustable radio frequency ablation needle
EP4085858A4 (en) * 2019-12-31 2024-02-21 Hangzhou Broncus Medical Co Ltd Detection mechanism, radio-frequency ablation catheter and radio-frequency ablation system
WO2022141769A1 (en) * 2020-12-31 2022-07-07 杭州堃博生物科技有限公司 Radio-frequency ablation catheter and radio-frequency ablation system

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Publication number Publication date
ITBS20020042A1 (en) 2003-10-23
AU2003230218A1 (en) 2003-11-10

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