WO2003073817A3 - Rapid and sensitive detection of cells and viruses - Google Patents

Rapid and sensitive detection of cells and viruses Download PDF

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Publication number
WO2003073817A3
WO2003073817A3 PCT/US2002/028434 US0228434W WO03073817A3 WO 2003073817 A3 WO2003073817 A3 WO 2003073817A3 US 0228434 W US0228434 W US 0228434W WO 03073817 A3 WO03073817 A3 WO 03073817A3
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WO
WIPO (PCT)
Prior art keywords
viruses
cells
rapid
sensitive detection
detection
Prior art date
Application number
PCT/US2002/028434
Other languages
French (fr)
Other versions
WO2003073817A2 (en
Inventor
Don Straus
Original Assignee
Genomic Profiling Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23234687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2003073817(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genomic Profiling Systems Inc filed Critical Genomic Profiling Systems Inc
Priority to JP2003572353A priority Critical patent/JP2005518553A/en
Priority to CA2460212A priority patent/CA2460212C/en
Priority to EP02807017A priority patent/EP1502101B1/en
Priority to AU2002365913A priority patent/AU2002365913A1/en
Publication of WO2003073817A2 publication Critical patent/WO2003073817A2/en
Publication of WO2003073817A3 publication Critical patent/WO2003073817A3/en
Priority to HK05103007.0A priority patent/HK1070424A1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/06—Quantitative determination
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y20/00—Nanooptics, e.g. quantum optics or photonic crystals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
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    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G01N15/1433—
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1486—Counting the particles
    • G—PHYSICS
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    • G01N15/10—Investigating individual particles
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    • G01N2015/1488—Methods for deciding
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    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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Abstract

Method for the rapid and sensitive detection of cells or viruses in a sample. The method involves the use of labeled category-binding molecules that bind to category-specific binding sites on the target cells or viruses, thereby allowing the detection of the target cells or viruses.
PCT/US2002/028434 2001-09-06 2002-09-06 Rapid and sensitive detection of cells and viruses WO2003073817A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2003572353A JP2005518553A (en) 2001-09-06 2002-09-06 Rapid and sensitive detection method for cells and viruses
CA2460212A CA2460212C (en) 2001-09-06 2002-09-06 Rapid and sensitive detection of cells and viruses
EP02807017A EP1502101B1 (en) 2001-09-06 2002-09-06 Rapid and sensitive detection of cells and viruses
AU2002365913A AU2002365913A1 (en) 2001-09-06 2002-09-06 Rapid and sensitive detection of cells and viruses
HK05103007.0A HK1070424A1 (en) 2001-09-06 2005-04-08 Rapid and sensitive detection of cells and viruses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31765801P 2001-09-06 2001-09-06
US60/317,658 2001-09-06

Publications (2)

Publication Number Publication Date
WO2003073817A2 WO2003073817A2 (en) 2003-09-12
WO2003073817A3 true WO2003073817A3 (en) 2004-12-02

Family

ID=23234687

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2002/028434 WO2003073817A2 (en) 2001-09-06 2002-09-06 Rapid and sensitive detection of cells and viruses
PCT/US2002/028506 WO2003022999A2 (en) 2001-09-06 2002-09-06 Rapid detection of replicating cells
PCT/US2002/028411 WO2003036290A1 (en) 2001-09-06 2002-09-06 Rapid and sensitive detection of molecules

Family Applications After (2)

Application Number Title Priority Date Filing Date
PCT/US2002/028506 WO2003022999A2 (en) 2001-09-06 2002-09-06 Rapid detection of replicating cells
PCT/US2002/028411 WO2003036290A1 (en) 2001-09-06 2002-09-06 Rapid and sensitive detection of molecules

Country Status (12)

Country Link
US (7) US10000788B2 (en)
EP (6) EP3252139A1 (en)
JP (3) JP2005518553A (en)
CN (3) CN100354430C (en)
AT (2) ATE470859T1 (en)
AU (2) AU2002323649A1 (en)
CA (3) CA2459320C (en)
DE (2) DE60236672D1 (en)
DK (3) DK2311934T3 (en)
ES (3) ES2635912T3 (en)
HK (1) HK1070424A1 (en)
WO (3) WO2003073817A2 (en)

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US9110025B2 (en) 2010-03-01 2015-08-18 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
CN104263837B (en) * 2014-10-13 2016-03-23 江南大学 The trimerical surface enhanced Raman scattering effect of golden nanometer particle modified based on triple beacon detects Hg in the aqueous solution 2+and/or Ag +method
US9310360B2 (en) 2010-03-01 2016-04-12 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
US9395359B2 (en) 2006-02-21 2016-07-19 Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US9551663B2 (en) 2010-03-01 2017-01-24 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles

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