WO2003071384A3 - Systems and methods for flow detection and measurement in csf shunts - Google Patents

Systems and methods for flow detection and measurement in csf shunts Download PDF

Info

Publication number
WO2003071384A3
WO2003071384A3 PCT/US2003/004470 US0304470W WO03071384A3 WO 2003071384 A3 WO2003071384 A3 WO 2003071384A3 US 0304470 W US0304470 W US 0304470W WO 03071384 A3 WO03071384 A3 WO 03071384A3
Authority
WO
WIPO (PCT)
Prior art keywords
csf
patients
methods
measurement
systems
Prior art date
Application number
PCT/US2003/004470
Other languages
French (fr)
Other versions
WO2003071384A2 (en
Inventor
Tom Saul
Original Assignee
Eunoe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eunoe Inc filed Critical Eunoe Inc
Priority to AU2003211060A priority Critical patent/AU2003211060A1/en
Publication of WO2003071384A2 publication Critical patent/WO2003071384A2/en
Publication of WO2003071384A3 publication Critical patent/WO2003071384A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
    • A61M27/006—Cerebrospinal drainage; Accessories therefor, e.g. valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

Devices and methods for removing cerebrospinal fluid (CSF) from a CSF space of a patient at relatively constant flow rates for patients having normal intracranial pressures, e.g. patients not suffering from hydrocephalus. The devices and methods provide drainage paths which permit the removal of CSF at relatively low flow rates, usually below 0.2 ml/day, at normal intracranial pressures, e.g. an intracranial pressure between -170 mm of H2O in upright patients and 200 mm of H2O in reclining patients. The removal of CSF at relatively low, constant rates is particularly suitable for treating Alzheimer's disease and other conditions related to the presence of toxic and/or pathogenic substances in the CSF.
PCT/US2003/004470 2002-02-15 2003-02-14 Systems and methods for flow detection and measurement in csf shunts WO2003071384A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003211060A AU2003211060A1 (en) 2002-02-15 2003-02-14 Systems and methods for flow detection and measurement in csf shunts

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35740102P 2002-02-15 2002-02-15
US60/357,401 2002-02-15

Publications (2)

Publication Number Publication Date
WO2003071384A2 WO2003071384A2 (en) 2003-08-28
WO2003071384A3 true WO2003071384A3 (en) 2003-12-31

Family

ID=27757613

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/004470 WO2003071384A2 (en) 2002-02-15 2003-02-14 Systems and methods for flow detection and measurement in csf shunts

Country Status (3)

Country Link
US (1) US20040068201A1 (en)
AU (1) AU2003211060A1 (en)
WO (1) WO2003071384A2 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7351214B2 (en) * 2002-03-22 2008-04-01 Cordis Corporation Steerable balloon catheter
US20030216710A1 (en) * 2002-03-26 2003-11-20 Hurt Robert F. Catheter
US9694166B2 (en) 2002-03-26 2017-07-04 Medtronics Ps Medical, Inc. Method of draining cerebrospinal fluid
US7520862B2 (en) * 2004-02-03 2009-04-21 Neuro Diagnostic Devices, Inc. Cerebral spinal fluid shunt evaluation system
US20050204811A1 (en) * 2004-02-03 2005-09-22 Neff Samuel R System and method for measuring flow in implanted cerebrospinal fluid shunts
US7036369B2 (en) * 2004-06-30 2006-05-02 Codman & Shurtleff, Inc. Thermal flow sensor having recesses in a substrate
US7069779B2 (en) * 2004-06-30 2006-07-04 Codman & Shurtleff, Inc. Thermal flow sensor having an inverted substrate
WO2006091581A1 (en) * 2005-02-22 2006-08-31 Richard Saunders Controllable shunt
US9072866B2 (en) 2007-04-13 2015-07-07 Neuro Diagnostic Devices, Inc. Cerebrospinal fluid evaluation system having thermal flow and flow rate measurement pad using a plurality of control sensors
WO2009146075A1 (en) * 2008-04-04 2009-12-03 Neuro Diagnostic Devices, Inc. Cerebrospinal fluid evaluation system having thermal flow and flow rate measurement pad using a plurality of control sensors
US20090005701A1 (en) * 2007-06-29 2009-01-01 Codman & Shurtleff, Inc. Cradled Sensor Assembly
US20090204019A1 (en) * 2008-02-13 2009-08-13 Alec Ginggen Combined Pressure and Flow Sensor Integrated in a Shunt System
FR2928553B1 (en) * 2008-03-14 2012-03-02 Sophysa Sa METHOD FOR REGULATING LCR DRAINAGE
WO2009155538A1 (en) * 2008-06-20 2009-12-23 Merck & Co., Inc. Compositions and methods of depleting amyloid-beta peptides from cerebrospinal fluid to treat alzheimer's disease
EP2300787B1 (en) 2008-07-08 2017-03-29 Koninklijke Philips N.V. Sensor and control unit for flow control and a method for controlled delivery of fluid
EP2330970A1 (en) * 2008-07-18 2011-06-15 Neckarate GmbH & Co. KG System for regulating intracranial pressure
WO2010075479A2 (en) * 2008-12-22 2010-07-01 Integrated Sensing Systems, Inc. Wireless dynamic power control of an implantable sensing device and methods therefor
US8088091B2 (en) 2009-03-09 2012-01-03 New Jersey Institute Of Technology No clog shunt using a compact fluid drag path
US9138568B2 (en) 2010-05-21 2015-09-22 Shuntcheck, Inc. CSF shunt flow enhancer, method for generating CSF flow in shunts and assessment of partial and complete occlusion of CSF shunt systems
WO2011150323A2 (en) * 2010-05-28 2011-12-01 Neurodx Development, Llc Real time csf flow measurement system & method
US20150201882A1 (en) * 2012-08-02 2015-07-23 Shuntcheck, Inc. Continuous real-time csf flow monitor and method
US10499816B2 (en) 2012-12-06 2019-12-10 Shuntcheck, Inc. CSF shunt flow evaluation apparatus and method using a conformable expanded dynamic range thermosensor
JP6498613B2 (en) 2013-01-22 2019-04-10 アヌンシア・インコーポレイテッド System and method for diverting fluid
US10183143B2 (en) 2013-03-15 2019-01-22 Bitol Designs, Llc Occlusion resistant catheter and method of use
CN103706025A (en) * 2013-12-23 2014-04-09 李桂亮 Embedded type subarachnoid space microscale slow-release syringe
JP6608391B2 (en) 2014-04-18 2019-11-20 アヌンシア・インコーポレイテッド System and method for diverting fluid
WO2016115208A1 (en) * 2015-01-14 2016-07-21 University Of Southern California Multi-sensor platform for diagnosing catheter status
US10226193B2 (en) 2015-03-31 2019-03-12 Medtronic Ps Medical, Inc. Wireless pressure measurement and monitoring for shunts
CA3044463A1 (en) 2016-10-13 2018-04-19 Alcyone Lifesciences, Inc. Shunt flushers and related methods
EP4285981A3 (en) * 2018-03-30 2024-02-21 Northwestern University Wireless and noninvasive epidermal electronics

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4858615A (en) * 1981-11-10 1989-08-22 Sentron V.O.F. Catheter sensor and memory unit
US5385541A (en) * 1992-04-24 1995-01-31 Loma Linda University Medical Center Cerebrospinal fluid shunt capable of minimal invasive revision
US5704352A (en) * 1995-11-22 1998-01-06 Tremblay; Gerald F. Implantable passive bio-sensor
US5980480A (en) * 1996-07-11 1999-11-09 Cs Fluids, Inc. Method and apparatus for treating adult-onset dementia of the alzheimer's type

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3913587A (en) * 1973-12-10 1975-10-21 Dow Corning Implantable extendable member
US3889687A (en) * 1974-01-31 1975-06-17 Donald L Harris Shunt system for the transport of cerebrospinal fluid
US3985140A (en) * 1975-06-30 1976-10-12 Cordis Corporation Dual pressure valve for use in ventricular shunt system
US4385636A (en) * 1978-05-23 1983-05-31 Cosman Eric R Telemetric differential pressure sensor with the improvement of a conductive shorted loop tuning element and a resonant circuit
IT1119233B (en) * 1979-10-17 1986-03-03 Michele Labianca REFERENCES IN CATHETERS FOR CEREBROSPINAL FLUID DERIVATION SYSTEMS FOR HYDROCEPHALY
US4377169A (en) * 1981-06-10 1983-03-22 Banks Bruce A Ion beam sputter-etched ventricular catheter for hydrocephalus shunt
US4432853A (en) * 1981-06-10 1984-02-21 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method of making an ion beam sputter-etched ventricular catheter for hydrocephalus shunt
US4769002A (en) * 1983-02-17 1988-09-06 Cordis Corporation Intercranial pressure regulator valve
US4540400A (en) * 1983-02-17 1985-09-10 Cordis Corporation Non-invasively adjustable valve
US4551128A (en) * 1983-05-11 1985-11-05 Salomon Hakim Cerebrospinal fluid shunt valve
US4615691A (en) * 1983-12-08 1986-10-07 Salomon Hakim Surgically-implantable stepping motor
US4595390A (en) * 1983-07-21 1986-06-17 Salomon Hakim Magnetically-adjustable cerebrospinal fluid shunt valve
US4557721A (en) * 1983-11-29 1985-12-10 Cordis Corporation Servo valve
US4772257A (en) * 1983-12-08 1988-09-20 Salomon Hakim External programmer for magnetically-adjustable cerebrospinal fluid shunt valve
US4776838A (en) * 1983-12-08 1988-10-11 Cordis Corporation Three stage valve
US4532932A (en) * 1984-01-03 1985-08-06 Cordis Corporation Implant communication system with frequency shift means
US4576035A (en) * 1984-01-05 1986-03-18 Cordis Corporation Self-calibrating differential condition sensor
US4627832A (en) * 1984-05-08 1986-12-09 Cordis Corporation Three stage intracranial pressure relief valve having single-piece valve stem
US4601721A (en) * 1984-09-17 1986-07-22 William Kamerling Posterior chamber intra-ocular device
US4631051A (en) * 1984-09-24 1986-12-23 Cordis Corporation Ventricular amniotic shunt and introducer system
US4598579A (en) * 1984-10-23 1986-07-08 Cordis Corporation Portable instrument to test pressure/flow of ventricular shunt valves
US4681559A (en) * 1985-12-23 1987-07-21 Cordis Corporation Plural valve three stage pressure relief system
US4714459A (en) * 1985-12-23 1987-12-22 Cordis Corporation Three stage intracranial pressure control valve
US4705499A (en) * 1985-12-23 1987-11-10 Cordis Corporation Implantable servo valve having integral pressure sensor
US4714458A (en) * 1985-12-23 1987-12-22 Cordis Corporation Three stage valve with flexible valve seat
US4675003A (en) * 1985-12-23 1987-06-23 Cordis Corporation Three stage pressure regulator valve
US4676772A (en) * 1985-12-23 1987-06-30 Cordis Corporation Adjustable implantable valve having non-invasive position indicator
US4781672A (en) * 1986-10-21 1988-11-01 Cordis Corporation Three stage implantable flow control valve with improved valve closure member
US4850955A (en) * 1986-12-02 1989-07-25 Codman & Shurtleff Body fluid transfer device
US4787886A (en) * 1987-02-05 1988-11-29 Cosman Eric R Pressure sensor controlled valve
US5039511A (en) * 1987-04-08 1991-08-13 Salutar, Inc. Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor
US4950232A (en) * 1987-08-11 1990-08-21 Surelab Superior Research Laboratories Cerebrospinal fluid shunt system
US4867740A (en) * 1988-03-24 1989-09-19 Pudenz-Schulte Medical Research Corp. Multiple-membrane flow control valve and implantable shunt system
US4861331A (en) * 1988-03-24 1989-08-29 Pudenz-Schulte Medical Research Corp. Implantable shunt system and method of assembly
US5069663A (en) * 1988-10-11 1991-12-03 Cordis Corporation Hydrocephalus valve
FR2685206B1 (en) * 1991-12-19 1998-03-06 Cordis Sa IMPLANTABLE DRAINAGE DEVICE FOR THE TREATMENT OF HYDROCEPHALIA.
US5334315A (en) * 1992-01-17 1994-08-02 Pall Corporation Priming system
EP0617975B1 (en) * 1992-01-22 1997-08-20 Cordis S.A. Implantable drainage valve for the treatment of hydrocephalus
FR2695564B1 (en) * 1992-09-15 1994-12-02 Cordis Sa Implantable valve for the treatment of hydrocephalus.
EP0600413A3 (en) * 1992-11-30 1995-04-05 Neuro Navigational Corp Neuro endoscope for shunt.
US5873835A (en) * 1993-04-29 1999-02-23 Scimed Life Systems, Inc. Intravascular pressure and flow sensor
US5387188A (en) * 1993-05-10 1995-02-07 Pudenz-Schulte Medical Research Corporation Pulsatile flow-accommodating fluid shunt
US5357967A (en) * 1993-06-04 1994-10-25 Baxter International Inc. Method and apparatus for measuring flow using frequency-dispersive techniques
HRP940025A2 (en) * 1994-01-14 1996-06-30 Branko Breyer A blood flow velocity measurement system perpendicular to a single probing beam
WO1995026677A1 (en) * 1994-03-30 1995-10-12 Pacesetter Ab Blood flow velocity measurement device
US5685989A (en) * 1994-09-16 1997-11-11 Transonic Systems, Inc. Method and apparatus to measure blood flow and recirculation in hemodialysis shunts
US6153109A (en) * 1994-09-16 2000-11-28 Transonic Systmes, Inc. Method and apparatus to measure blood flow rate in hemodialysis shunts
US5598847A (en) * 1994-12-28 1997-02-04 Pacesetter, Inc. Implantable flow sensor apparatus and method
US5557967A (en) * 1995-02-24 1996-09-24 Pacesetter, Inc. Thermopile flow sensor
WO1996028200A1 (en) * 1995-03-16 1996-09-19 Medtronic Ps Medical Partially disposable surgical imaging assembly
US6258046B1 (en) * 1995-07-06 2001-07-10 Institute Of Critical Care Medicine Method and device for assessing perfusion failure in a patient by measurement of blood flow
US5860922A (en) * 1995-09-07 1999-01-19 Technion Research And Development Foundation Ltd. Determining blood flow by measurement of temperature
US5833603A (en) * 1996-03-13 1998-11-10 Lipomatrix, Inc. Implantable biosensing transponder
FR2746659B1 (en) * 1996-03-26 1998-06-19 Cordis Sa VALVE FOR THE TREATMENT OF HYDROCEPHALIA
FR2746658B1 (en) * 1996-03-26 1998-06-19 Cordis Sa IMPLANTABLE DRAINAGE VALVE FOR THE TREATMENT OF HYDROCEPHALIA
US5931039A (en) * 1996-04-10 1999-08-03 Hitachi Koki Co., Ltd. Electrical bar cutting and bending tool
US6383159B1 (en) * 1998-11-10 2002-05-07 Eunoe, Inc. Devices and method for removing cerebrospinal fluids from a patient's CSF space
US6120460A (en) * 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
GB9623363D0 (en) * 1996-11-09 1997-01-08 Moor Instr Ltd Apparatus for measuring microvascular blood flow
US6306098B1 (en) * 1996-12-19 2001-10-23 Novametrix Medical Systems Inc. Apparatus and method for non-invasively measuring cardiac output
US6015387A (en) * 1997-03-20 2000-01-18 Medivas, Llc Implantation devices for monitoring and regulating blood flow
US6012415A (en) * 1997-04-18 2000-01-11 Magtronic Id, Inc. Bolus with animal ID and temperature transponder
US6731976B2 (en) * 1997-09-03 2004-05-04 Medtronic, Inc. Device and method to measure and communicate body parameters
US5989192A (en) * 1997-09-25 1999-11-23 Medtronic, Inc. Cardiac flow sensor
US6021415A (en) * 1997-10-29 2000-02-01 International Business Machines Corporation Storage management system with file aggregation and space reclamation within aggregated files
US5967987A (en) * 1997-12-18 1999-10-19 Acuson Corporation Ultrasonic system and method for measurement of fluid flow
US6293914B1 (en) * 1998-08-31 2001-09-25 Acuson Corporation Ultrasonic system and method for measurement of fluid flow
US6170488B1 (en) * 1999-03-24 2001-01-09 The B. F. Goodrich Company Acoustic-based remotely interrogated diagnostic implant device and system
US6533733B1 (en) * 1999-09-24 2003-03-18 Ut-Battelle, Llc Implantable device for in-vivo intracranial and cerebrospinal fluid pressure monitoring
US20050055009A1 (en) * 2003-09-05 2005-03-10 Codman & Shurtleff, Inc. Method and apparatus for managing normal pressure hydrocephalus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4858615A (en) * 1981-11-10 1989-08-22 Sentron V.O.F. Catheter sensor and memory unit
US5385541A (en) * 1992-04-24 1995-01-31 Loma Linda University Medical Center Cerebrospinal fluid shunt capable of minimal invasive revision
US5704352A (en) * 1995-11-22 1998-01-06 Tremblay; Gerald F. Implantable passive bio-sensor
US5980480A (en) * 1996-07-11 1999-11-09 Cs Fluids, Inc. Method and apparatus for treating adult-onset dementia of the alzheimer's type

Also Published As

Publication number Publication date
US20040068201A1 (en) 2004-04-08
AU2003211060A8 (en) 2003-09-09
AU2003211060A1 (en) 2003-09-09
WO2003071384A2 (en) 2003-08-28

Similar Documents

Publication Publication Date Title
WO2003071384A3 (en) Systems and methods for flow detection and measurement in csf shunts
US6383159B1 (en) Devices and method for removing cerebrospinal fluids from a patient's CSF space
BRPI0403756A (en) Method and apparatus for the management of normal pressure hydrocephalus
US7722557B2 (en) Blood purification apparatus
CA2156721A1 (en) Removal of Selected Factors from Whole Blood or Its Components
WO2007007129A3 (en) Diagnostic method for brain damage-related disorders
WO2005012183A3 (en) Stormwater treatment system
WO2004069030A8 (en) Medical and surgical devices with an integrated sensor
WO2006083559A3 (en) System and method for treating glaucoma
WO2009064984A3 (en) Dialysis systems and methods
CO5700177A1 (en) HIGH-INTERVAL HYDROCEPHAL VALVE VALVE SYSTEM
BRPI0604359B8 (en) "cassette and surgical system"
WO2002036068A3 (en) Extracorporeal circuit for peripheral vein fluid removal
WO2001037899A3 (en) Extracorporeal circuits for performing hemofiltration employing pressure sensing without an air interface
WO2007116387A3 (en) A fluid flow indicator
CA2356032A1 (en) Shunt
ATE319490T1 (en) CATHETER FOR CARDIAC SUPPORT, CATHETER PUMP FOR CARDIAC SUPPORT AND FITTING FOR SUCH A CATHETER
AU3490299A (en) Method of measuring intracranial pressure
WO2003033122A3 (en) Apparatus for fluid purification and methods of manufacture and use thereof
WO2002003854A3 (en) System elements for measuring pressure in extracorporeal circuits
WO2008028653A3 (en) Device and method for monitoring an access to a patient, in particular a vascular access in extracorporeal blood treatment
DE50012725D1 (en) CONTINUOUS NON-INVASIVE BLOOD PRESSURE METER
HK1087606A1 (en) Sensor in vivo measurement of osmotic changes
WO2004061399A3 (en) Pressure detector for fluid circuits
JP2020124526A5 (en)

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP