WO2003068294A2 - Device for administering of medication in fluid form - Google Patents
Device for administering of medication in fluid form Download PDFInfo
- Publication number
- WO2003068294A2 WO2003068294A2 PCT/DK2003/000107 DK0300107W WO03068294A2 WO 2003068294 A2 WO2003068294 A2 WO 2003068294A2 DK 0300107 W DK0300107 W DK 0300107W WO 03068294 A2 WO03068294 A2 WO 03068294A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- medication
- fluid
- chamber
- communication
- storage
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16877—Adjusting flow; Devices for setting a flow rate
- A61M5/16881—Regulating valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/141—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor with capillaries for restricting fluid flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M2005/1401—Functional features
- A61M2005/1405—Patient controlled analgesia [PCA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0272—Electro-active or magneto-active materials
- A61M2205/0294—Piezoelectric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
- A61M5/152—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags pressurised by contraction of elastic reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
- A61M5/16813—Flow controllers by controlling the degree of opening of the flow line
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
- A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
Landscapes
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03706332A EP1476209B1 (en) | 2002-02-18 | 2003-02-18 | Device for administering of medication in fluid form |
AU2003208305A AU2003208305A1 (en) | 2002-02-18 | 2003-02-18 | Device for administering of medication in fluid form |
JP2003567474A JP4002892B2 (en) | 2002-02-18 | 2003-02-18 | Device for administering a drug in liquid form |
DE60322512T DE60322512D1 (en) | 2002-02-18 | 2003-02-18 | DEVICE FOR THE ADMINISTRATION OF A MEDICAMENT IN LIQUID FORM |
US10/503,845 US7517335B2 (en) | 2002-02-18 | 2003-02-18 | Device for administering of medication in fluid form |
US12/195,791 US8945064B2 (en) | 2002-02-18 | 2008-08-21 | Device for administering of medication in fluid form |
US14/592,370 US20150190574A1 (en) | 2002-02-18 | 2015-01-08 | Device for Administering of Medication in Fluid Form |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200200240 | 2002-02-18 | ||
DKPA200200240 | 2002-02-18 | ||
DKPA200200970 | 2002-06-25 | ||
DKPA200200970 | 2002-06-25 |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10503845 A-371-Of-International | 2003-02-18 | ||
US10/503,845 A-371-Of-International US7517335B2 (en) | 2002-02-18 | 2003-02-18 | Device for administering of medication in fluid form |
US12/195,791 Continuation US8945064B2 (en) | 2002-02-18 | 2008-08-21 | Device for administering of medication in fluid form |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003068294A2 true WO2003068294A2 (en) | 2003-08-21 |
WO2003068294A3 WO2003068294A3 (en) | 2003-12-31 |
Family
ID=27735960
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DK2003/000107 WO2003068294A2 (en) | 2002-02-18 | 2003-02-18 | Device for administering of medication in fluid form |
Country Status (9)
Country | Link |
---|---|
US (3) | US7517335B2 (en) |
EP (2) | EP2077130A3 (en) |
JP (1) | JP4002892B2 (en) |
CN (2) | CN100418588C (en) |
AT (1) | ATE402724T1 (en) |
AU (1) | AU2003208305A1 (en) |
DE (1) | DE60322512D1 (en) |
RU (1) | RU2279898C2 (en) |
WO (1) | WO2003068294A2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006037330A1 (en) * | 2004-10-08 | 2006-04-13 | Danfoss A/S | A pumping system and a method for controlling a fluid flow in a pumping system |
WO2006131115A1 (en) * | 2005-06-04 | 2006-12-14 | Danfoss A/S | Connector for a flow system |
AU2005201894B2 (en) * | 2004-05-28 | 2011-05-12 | Ethicon Endo-Surgery, Inc. | Thermodynamically driven reversible infuser pump for use as a remotely controlled gastic band |
WO2012054741A1 (en) * | 2010-10-22 | 2012-04-26 | Cequr Sa | Methods and systems for dosing a medicament |
Families Citing this family (45)
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US20080172026A1 (en) | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump having a suspension bolus |
ES2737835T3 (en) | 2003-04-23 | 2020-01-16 | Valeritas Inc | Hydraulically driven pump for long-term medication administration |
US7374565B2 (en) * | 2004-05-28 | 2008-05-20 | Ethicon Endo-Surgery, Inc. | Bi-directional infuser pump with volume braking for hydraulically controlling an adjustable gastric band |
WO2006014425A1 (en) | 2004-07-02 | 2006-02-09 | Biovalve Technologies, Inc. | Methods and devices for delivering glp-1 and uses thereof |
WO2006061020A1 (en) * | 2004-12-08 | 2006-06-15 | Danfoss A/S | Bubble-tolerant micro-mixers |
JP2009532117A (en) | 2006-03-30 | 2009-09-10 | ヴァレリタス,エルエルシー | Multi-cartridge fluid dispensing device |
US7875004B2 (en) * | 2006-06-08 | 2011-01-25 | Medingo Ltd. | Method and system for detecting an occlusion in a tube |
DE102007047351A1 (en) * | 2007-10-02 | 2009-04-09 | B. Braun Melsungen Ag | System and method for monitoring and controlling blood glucose levels |
DE102007049446A1 (en) | 2007-10-16 | 2009-04-23 | Cequr Aps | Catheter introducer |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
US8065924B2 (en) * | 2008-05-23 | 2011-11-29 | Hospira, Inc. | Cassette for differential pressure based medication delivery flow sensor assembly for medication delivery monitoring and method of making the same |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
US8650937B2 (en) | 2008-09-19 | 2014-02-18 | Tandem Diabetes Care, Inc. | Solute concentration measurement device and related methods |
EP3677293A1 (en) | 2009-01-12 | 2020-07-08 | Becton, Dickinson and Company | In-dwelling rigid catheter with flexible features |
US8230744B2 (en) | 2009-05-06 | 2012-07-31 | Cequr Sa | Low-dead volume microfluidic circuit and methods |
EP2724739B1 (en) | 2009-07-30 | 2015-07-01 | Tandem Diabetes Care, Inc. | Portable infusion pump system |
US8547239B2 (en) | 2009-08-18 | 2013-10-01 | Cequr Sa | Methods for detecting failure states in a medicine delivery device |
JP2012061053A (en) * | 2010-09-14 | 2012-03-29 | Yuuki Kitaoka | Administration apparatus, method of operating the same, and administration method |
JP2012066004A (en) * | 2010-09-27 | 2012-04-05 | Ricoh Co Ltd | Solution sending system, solution sending method and program |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US9555186B2 (en) | 2012-06-05 | 2017-01-31 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
US9572931B2 (en) | 2012-06-26 | 2017-02-21 | Ambu A/S | Device, system and method for self-administration of a treatment fluid |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
US20150133861A1 (en) | 2013-11-11 | 2015-05-14 | Kevin P. McLennan | Thermal management system and method for medical devices |
US10556059B2 (en) * | 2013-12-31 | 2020-02-11 | Biogen Ma Inc. | Infusion pump drive with compression spring |
KR102506249B1 (en) | 2014-06-03 | 2023-03-03 | 암겐 인코포레이티드 | Drug delivery system and method of use |
US10143795B2 (en) | 2014-08-18 | 2018-12-04 | Icu Medical, Inc. | Intravenous pole integrated power, control, and communication system and method for an infusion pump |
EP3233159B1 (en) | 2014-12-19 | 2020-03-04 | Amgen Inc. | Drug delivery device with live button or user interface field |
JP6716566B2 (en) | 2014-12-19 | 2020-07-01 | アムジエン・インコーポレーテツド | Drug delivery device with proximity sensor |
EP3280471A2 (en) | 2015-04-08 | 2018-02-14 | Cequr SA | Combined medicament fill and cannula insertion device |
CA2987011A1 (en) | 2015-05-26 | 2016-12-01 | Icu Medical, Inc. | Disposable infusion fluid delivery device for programmable large volume drug delivery |
US10258741B2 (en) | 2016-12-28 | 2019-04-16 | Cequr Sa | Microfluidic flow restrictor and system |
US20210030952A1 (en) | 2018-02-16 | 2021-02-04 | Cequr Sa | Devices and methods for flow restriction in a microfluidic circuit for drug delivery |
WO2019211407A1 (en) | 2018-05-02 | 2019-11-07 | Cequr Sa | Devices and methods for providing a bolus dose in a microfluidic circuit of a pump |
DE102018211140A1 (en) * | 2018-07-05 | 2020-01-09 | B. Braun Melsungen Ag | Medical pump device for conveying a medical fluid |
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EP3705148A1 (en) | 2019-03-04 | 2020-09-09 | Avoset Health Ltd. | In cycle pressure measurement |
WO2020178827A1 (en) | 2019-03-05 | 2020-09-10 | Avoset Health Ltd. | Anti-free-flow valve |
USD939079S1 (en) | 2019-08-22 | 2021-12-21 | Icu Medical, Inc. | Infusion pump |
CN110960747B (en) * | 2019-12-19 | 2021-08-06 | 山东大学齐鲁医院 | High-precision analgesia pump and working method |
CN110975058B (en) * | 2019-12-19 | 2021-08-10 | 齐鲁理工学院 | Automatically-adjustable analgesia pump and working method |
CN110898290B (en) * | 2019-12-31 | 2021-07-30 | 山东大学齐鲁医院 | Multifunctional portable infusion device and working method |
CN111068173B (en) * | 2020-01-03 | 2022-07-29 | 上海旭润医学科技有限责任公司 | Disposable wearable micro-flow continuous drug delivery system |
CN112274725B (en) * | 2020-12-24 | 2021-03-09 | 时新(上海)产品设计有限公司 | Medium infusion structure, medium infusion method, microdose secretion pump and insulin pump |
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- 2003-02-18 JP JP2003567474A patent/JP4002892B2/en not_active Expired - Fee Related
- 2003-02-18 WO PCT/DK2003/000107 patent/WO2003068294A2/en active IP Right Grant
- 2003-02-18 EP EP08013595A patent/EP2077130A3/en not_active Withdrawn
- 2003-02-18 US US10/503,845 patent/US7517335B2/en not_active Expired - Fee Related
- 2003-02-18 DE DE60322512T patent/DE60322512D1/en not_active Expired - Lifetime
- 2003-02-18 CN CNB038041235A patent/CN100418588C/en not_active Expired - Fee Related
- 2003-02-18 AT AT03706332T patent/ATE402724T1/en not_active IP Right Cessation
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Also Published As
Publication number | Publication date |
---|---|
JP4002892B2 (en) | 2007-11-07 |
EP2077130A2 (en) | 2009-07-08 |
RU2279898C2 (en) | 2006-07-20 |
US20150190574A1 (en) | 2015-07-09 |
RU2004128441A (en) | 2005-04-10 |
EP1476209A2 (en) | 2004-11-17 |
CN1642588A (en) | 2005-07-20 |
EP1476209B1 (en) | 2008-07-30 |
US7517335B2 (en) | 2009-04-14 |
US20090054867A1 (en) | 2009-02-26 |
AU2003208305A8 (en) | 2003-09-04 |
CN100418588C (en) | 2008-09-17 |
US20050165384A1 (en) | 2005-07-28 |
US8945064B2 (en) | 2015-02-03 |
AU2003208305A1 (en) | 2003-09-04 |
DE60322512D1 (en) | 2008-09-11 |
JP2005517472A (en) | 2005-06-16 |
CN101380492B (en) | 2013-05-22 |
CN101380492A (en) | 2009-03-11 |
ATE402724T1 (en) | 2008-08-15 |
EP2077130A3 (en) | 2009-09-23 |
WO2003068294A3 (en) | 2003-12-31 |
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