WO2003057072A3 - Hemostatic compositions and methods for controlling bleeding - Google Patents

Hemostatic compositions and methods for controlling bleeding Download PDF

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Publication number
WO2003057072A3
WO2003057072A3 PCT/US2002/041748 US0241748W WO03057072A3 WO 2003057072 A3 WO2003057072 A3 WO 2003057072A3 US 0241748 W US0241748 W US 0241748W WO 03057072 A3 WO03057072 A3 WO 03057072A3
Authority
WO
WIPO (PCT)
Prior art keywords
hemostatic compositions
methods
controlling bleeding
polysaccharide
article
Prior art date
Application number
PCT/US2002/041748
Other languages
French (fr)
Other versions
WO2003057072A2 (en
WO2003057072A8 (en
Inventor
Kent C Cochrum
Susan Jemtrud
Original Assignee
Ares Lab Llc
Kent C Cochrum
Susan Jemtrud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Lab Llc, Kent C Cochrum, Susan Jemtrud filed Critical Ares Lab Llc
Priority to CA002471994A priority Critical patent/CA2471994A1/en
Priority to MXPA04006438A priority patent/MXPA04006438A/en
Priority to AU2002361902A priority patent/AU2002361902A1/en
Priority to JP2003557435A priority patent/JP2005514105A/en
Priority to EP02797532A priority patent/EP1469865A4/en
Publication of WO2003057072A2 publication Critical patent/WO2003057072A2/en
Publication of WO2003057072A3 publication Critical patent/WO2003057072A3/en
Publication of WO2003057072A8 publication Critical patent/WO2003057072A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Abstract

The invention provides hemostatic compositions useful to promote hemostasis at active bleeding wound sites. The hemostatic compositions typically include an article containing cellulose, e.g., cotton gauze, and a polysaccharide covalently linked to the cellulose, or a polysaccharide ionically cross-linked and in association with the article. Methods of making and using the hemostatic compositions are also provided.
PCT/US2002/041748 2001-12-31 2002-12-31 Hemostatic compositions and methods for controlling bleeding WO2003057072A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002471994A CA2471994A1 (en) 2001-12-31 2002-12-31 Hemostatic compositions and methods for controlling bleeding
MXPA04006438A MXPA04006438A (en) 2001-12-31 2002-12-31 Hemostatic compositions and methods for controlling bleeding.
AU2002361902A AU2002361902A1 (en) 2001-12-31 2002-12-31 Hemostatic compositions and methods for controlling bleeding
JP2003557435A JP2005514105A (en) 2001-12-31 2002-12-31 Hemostasis composition and method for controlling bleeding
EP02797532A EP1469865A4 (en) 2001-12-31 2002-12-31 Hemostatic compositions and methods for controlling bleeding

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US34324701P 2001-12-31 2001-12-31
US60/343,247 2001-12-31
US35491702P 2002-02-11 2002-02-11
US60/354,917 2002-02-11

Publications (3)

Publication Number Publication Date
WO2003057072A2 WO2003057072A2 (en) 2003-07-17
WO2003057072A3 true WO2003057072A3 (en) 2003-10-30
WO2003057072A8 WO2003057072A8 (en) 2004-07-08

Family

ID=26993389

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/041748 WO2003057072A2 (en) 2001-12-31 2002-12-31 Hemostatic compositions and methods for controlling bleeding

Country Status (7)

Country Link
US (3) US7101862B2 (en)
EP (1) EP1469865A4 (en)
JP (1) JP2005514105A (en)
AU (1) AU2002361902A1 (en)
CA (1) CA2471994A1 (en)
MX (1) MXPA04006438A (en)
WO (1) WO2003057072A2 (en)

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US20030175327A1 (en) 2003-09-18
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US20060141018A1 (en) 2006-06-29
MXPA04006438A (en) 2005-06-08
EP1469865A2 (en) 2004-10-27
WO2003057072A2 (en) 2003-07-17
WO2003057072A8 (en) 2004-07-08
EP1469865A4 (en) 2010-04-14
AU2002361902A8 (en) 2003-07-24
US20080020026A1 (en) 2008-01-24
JP2005514105A (en) 2005-05-19
US7101862B2 (en) 2006-09-05

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