WO2003053493A2 - Septal occluder and associated methods - Google Patents
Septal occluder and associated methods Download PDFInfo
- Publication number
- WO2003053493A2 WO2003053493A2 PCT/US2002/040850 US0240850W WO03053493A2 WO 2003053493 A2 WO2003053493 A2 WO 2003053493A2 US 0240850 W US0240850 W US 0240850W WO 03053493 A2 WO03053493 A2 WO 03053493A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- proximal
- septal
- distal anchor
- anchor member
- deployment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04M—TELEPHONIC COMMUNICATION
- H04M1/00—Substation equipment, e.g. for use by subscribers
- H04M1/68—Circuit arrangements for preventing eavesdropping
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04M—TELEPHONIC COMMUNICATION
- H04M1/00—Substation equipment, e.g. for use by subscribers
- H04M1/71—Substation extension arrangements
- H04M1/715—Substation extension arrangements using two or more extensions per line
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04M—TELEPHONIC COMMUNICATION
- H04M1/00—Substation equipment, e.g. for use by subscribers
- H04M1/72—Mobile telephones; Cordless telephones, i.e. devices for establishing wireless links to base stations without route selection
- H04M1/725—Cordless telephones
- H04M1/72502—Cordless telephones with one base station connected to a single line
- H04M1/72505—Radio link set-up procedures
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04W—WIRELESS COMMUNICATION NETWORKS
- H04W84/00—Network topologies
- H04W84/02—Hierarchically pre-organised networks, e.g. paging networks, cellular networks, WLAN [Wireless Local Area Network] or WLL [Wireless Local Loop]
- H04W84/10—Small scale networks; Flat hierarchical networks
- H04W84/14—WLL [Wireless Local Loop]; RLL [Radio Local Loop]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00592—Elastic or resilient implements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00606—Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0469—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
- A61B2017/0475—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery using sutures having a slip knot
Definitions
- a patent foramen ovale (PFO) as shown in FIGURE 1 is a persistent, one-way, usually flap-like opening in the wall between the right atrium 10 and left atrium 12 of the heart. Since left atrial (LA) pressure is normally higher than right atrial (RA) pressure, the flap typically stays closed. Under certain conditions, however, RA pressure can exceed LA pressure creating the possibility for right to left shunting that can allow blood clots to enter the systemic circulation. In utero, the foramen ovale serves as a physiologic conduit for right-to-left shunting. After birth, with the establishment of pulmonary circulation, the increased left atrial blood flow and pressure results in functional closure of the foramen ovale.
- LA left atrial
- RA right atrial
- septum primum 14 septum primum 14
- septum secundum 16 tissue over-lapping layers of tissue.
- TEE contrast echocardiography
- PFO has no therapeutic consequence in otherwise healthy adults.
- patients suffering a stroke or TIA in the presence of a PFO and without another cause of ischemic stroke are considered for prophylactic medical therapy to reduce the risk of a recurrent embolic event.
- These patients are commonly treated with oral anticoagulants, which have the potential for adverse side effects such as hemorrhaging, hematoma, and interactions with a variety of other drugs.
- surgery may be used to close a PFO.
- To suture a PFO closed requires attachment of septum secundum to septum primum with a continuous stitch, which is the common way a surgeon shuts the PFO under direct visualization.
- Non-surgical closure of PFOs has become possible with the advent of umbrella-like devices and a variety of other similar mechanical closure designs developed initially for percutaneous closure of atrial septal defects (ASD). These devices allow patients to avoid the potential side effects often associated with anticoagulation therapies.
- ASD atrial septal defects
- the closure devices generally include a proximal anchor member, a distal anchor member, and a flexible, center joint connecting the two anchor members.
- the center joint can be a suture.
- the center joint can be a flexible elastomeric layer, which can, e.g., be used to promote tissue ingrowth or for drug delivery.
- the flexible material can also be covered with a biocompatible glue to promote adherence to tissue or growth factors to accelerate tissue ingrowth.
- the closure device is formed of bioresorbable components such that substantially no permanent foreign body remains in the defect.
- mechanisms are provided to collapse the closure device for facilitating device delivery, removal and /or repositioning.
- FIGURE 1 is a cross-sectional view of a portion of the heart illustrating a PFO
- FIGURE 2 illustrates a deployed PFO closure device with bioresorbable components in accordance with one or more embodiments of the invention
- FIGURE 3 illustrates the PFO closure device of FIGURE 2 in a collapsed state for passage through a delivery catheter or sheath;
- FIGURE 4 illustrates a closure device deployed to close a PFO in accordance with one or more further embodiments of the invention
- FIGURE 5 illustrates a closure device deployed to close the PFO in accordance with one or more further embodiments of the invention
- FIGURES 6A and 6B are front and side views, respectively, of a PFO closure device in accordance with one or more further embodiments of the invention.
- FIGURES 7A and 7B are front and side views, respectively, of a PFO closure device in accordance with one or more further embodiments of the invention.
- FIGURES 8A and 8B are side and front views, respectively, of the PFO closure device of FIGURE 6 deployed to close a PFO;
- FIGURES 9A illustrates a closure device having a retrieval mechanism in accordance with one or more further embodiments of the invention in a collapsed state for passage through a catheter or sheath;
- FIGURE 9B is a front view of the FIGURE 9 A device
- FIGURES 9C-E illustrate deployment of the FIGURE 9A device
- FIGURES 9F-H illustrate removal of the FIGURE 9A device
- FIGURE 10A illustrates a closure device having a retrieval mechanism in accordance with one or more further embodiments of the invention in a collapsed state for passage through a catheter or sheath;
- FIGURE 10B is a front view of the FIGURE 10A device
- FIGURES 11 A and 11B illustrate an anchor member with an elastic hinge in accordance with one or more further embodiments of the invention
- FIGURE 12 illustrates a PFO closure device made from a single material in accordance with one or more further embodiments of the invention.
- FIGURE 13 illustrates a PFO closure device having inflatable anchor members in accordance with one or more further embodiments of the invention
- FIGURE 14 illustrates a PFO closure device with a wire connecting the proximal and distal anchor members in accordance with one or more further embodiments of the invention
- FIGURE 15 illustrates a PFO closure device having a frame member in accordance with one or more further embodiments of the invention
- FIGURE 16 illustrates a PFO closure device having frame anchor members in accordance with one or more further embodiments of the invention
- FIGURE 17 illustrates a PFO closure device having frame anchor members in accordance with one or more further embodiments of the invention.
- FIGURE 18 illustrates the FIGURE 17 device in a collapsed state for passage through a catheter or sheath
- FIGURE 19 illustrates a frame anchor member having metal and polymer components in accordance with one or more further embodiments of the invention.
- FIGURES 20A and 20B illustrate a PFO closure device having anchor members formed from a rolled material in accordance with one or more further embodiments of the invention in rolled and unrolled positions, respectively;
- FIGURES 21A and 21B illustrate an alternate PFO closure device having anchor members formed from a rolled material in accordance with one or more further embodiments of the invention in rolled and unrolled positions, respectively;
- FIGURES 22A illustrates a closure device having frame anchor members and a generally "X" shaped joint member in accordance with one or more further embodiments of the invention
- FIGURE 22B illustrates the proximal anchor member of the FIGURE 22A device
- FIGURE 22C illustrates the FIGURE 22A device in a deployed state
- FIGURES 23 illustrates a closure device having frame anchor members having a generally "+" shaped frame structure in accordance with one or more further embodiments of the invention.
- FIGURES 24 illustrates a closure device having frame anchor members having a generally "G" shaped frame structure in accordance with one or more further embodiments of the invention.
- Various embodiments of the present invention are directed to methods and devices for closing septal defects such as PFOs, primarily by eliciting a healing response at the defect.
- a PFO closure device 18 in accordance with one or more embodiments of the present invention includes a distal anchor component or member 20 (which can be placed on the left atrial side of the PFO), a proximal anchor member 22 (to fix the device in place), a proximal attachment point 24 (for attachment and release from a catheter), and a central connecting member 26 (which can, e.g., be a simple suture in accordance with this embodiment).
- the distal anchor, the proximal anchor, and the connecting member are bioresorbable. These components can be fabricated from either a single bioresorbable polymer or by a laminated composite of two or more materials to provide a unique mix of properties such as, e.g., anchor members having stiff centers and flexible edges, and blood contacting surfaces having controlled porosity or surface texture to promote fast and thorough endothelialization, while minimizing thrombosis.
- the tissue contacting surface of the anchors can be designed to provide added stability by, e.g., being roughened.
- the distal anchor 20 is an elongated, preferably generally cylindrical, thin bar-like member with rounded, arcuately shaped ends.
- the tissue contacting surface of the anchor can be generally flattened to increase tissue surface contact.
- the distal anchor component might, e.g., be 15-30 mm long and 2 mm in diameter with a circular cross-section.
- the proximal anchor 22 can be of similar dimensions and shape, although it can be shorter in overall length. Other distal and proximal anchor structures are also possible.
- the anchors can be formed of a generally flat material rolled to form a cylindrical shape as described below with respect to the embodiments of FIGURES 20 and 21.
- distal anchor 20 and proximal anchor 20 For delivery and deployment, the distal anchor 20 and proximal anchor
- a delivery sheath or catheter 28 are positioned to be generally aligned in a longitudinal, end-to-end manner within a delivery sheath or catheter 28 as shown in FIGURE 3. These components, with the flexible connecting member 26 traverse the catheter or delivery sheath in this longitudinal orientation.
- the catheter or delivery sheath is inserted between septum primum and septum secundum into the left atrium 18, and the distal anchor component 20 is ejected.
- the catheter or delivery sheath 28 is withdrawn into the right atrium, and the proximal anchor 22 is ejected.
- the flexible central connecting member 26 extends between septum primum and septum secundum to join the distal anchor 20 and the proximal anchor 22. Once ejected, the distal anchor and proximal anchor generally self-orientate to be essentially perpendicular to the axis of the central connecting member and in generally parallel planes to one another. The exact orientation will be governed by the individual patient anatomy.
- An alternate delivery method for this device can be to deploy it directly through the septum primum as opposed to through the PFO.
- the method of attaching the central connecting member 26 to the anchor and stop mechanism 22 to permit the distal anchor and the proximal anchor to be drawn together could be, e.g., via a friction fit or via a slip knot on the central connecting member. If a slip knot is used, the free end of the suture proximal to the knot can be held remotely and released after the knot has been placed in the appropriate location.
- the central connecting member 26 is mounted to permit free sliding movement of the proximal anchor 22 relative to the central connecting member 26.
- a biasing spring 30, which may be an expandable coil spring, can be formed at the outer end of the central connecting member 26 to bias the proximal anchor toward the distal anchor when both are deployed from the catheter or sheath.
- a metallic component may be used as the central connecting member 26 in order to provide an appropriate stop and apply compression force to the proximal anchor 22.
- the metallic component could be a piece of shape memory wire that has one end molded or laminated into the distal anchor component 20.
- the proximal anchor 22 slides on the central connecting member 26, and once it is deployed, the biasing spring 30 formed on the end of the shape memory wire expands to bias the proximal anchor 22 toward the distal anchor 20.
- a shape memory wire forms a hook type anchor 32 made from two wires that exit through the center of the proximate anchor and curve in opposite directions when expanded to draw the proximate anchor toward the distal anchor.
- FIGURES 4 and 5 can leave a permanent foreign body when the bioresorbable components dissolve (if, e.g., a metallic component is used as the central connecting member 26), one advantage of these devices is that no thrombogenic tissue scaffold (usually a vascular material) is placed on the left atrial side. Thrombus forming on the LA side of a PFO closure device can be released into the systemic circulation causing an embolic event within the coronary arteries, cerebral circulation, or distally in the vasculature, and most vascular graft materials utilized to close PFOs are highly thrombogenic.
- a metallic component is used as the central connecting member 26
- the PFO closure devices may need to be capable of x-ray visualization and use with radiopaque fillers or marker bands fabricated from noble metals such as platinum or gold. These markers can be attached using a variety of common methods such as, e.g., adhesive bonding, lamination between two layers of polymer, or vapor deposition.
- FIGURES 6A and 6B illustrate a closure device 50 in accordance with one or more further embodiments of the invention.
- the device 50 includes proximal and distal anchor members 52, 54 connected with a flexible (and preferably stretchable elastomeric) center joint or connecting element 56.
- the anchor members 52, 54 are preferably cylindrical in shape with rounded ends. In size, the distal anchor member 54 might, e.g., be about 15-30 mm long and about 2 mm in diameter with a circular cross-section.
- the proximal anchor 52 can be of similar dimensions and shape, although it can be shorter in overall length.
- the anchor members 52, 54 are preferably made from a rigid
- bioresorbable polymer preferably polymer (regular or shape memory), or biological tissue.
- Biocompatible metal can also be used.
- anchors can be formed of a generally flat material rolled to form a cylindrical shape as described below with respect to the embodiments of FIGURES 20 and 21.
- the center joint 56 of the FIGURE 6 device (as well as the center joints of the devices shown in FIGURES 7-10, 12-18, and 21 -24) are preferably elastomeric and resilient and are made from thrombogenic or inflammatory materials including, e.g., polyester, biological tissue, bioresorbable polymer, small diameter springs (e.g., Nitinol), or spongy polymeric material.
- the center joint can be made of multiple strands of material 58 such as, e.g., polymer fibers as shown in the closure device 60 of FIGURES 7A and 7B.
- the center joint can be textured, porous or in a form of a single or double-sided hook material such as Velcro. These kinds of surfaces produce inflammatory responses and therefore, promote faster tissue ingrowth and faster defect closure.
- the entire device or parts of it can be made from bioresorbable polymers.
- FIGURE 8A and 8B are front and side views, respectively, of the device 50 in a PFO defect.
- the proximal and distal anchor members 54, 52 are longer than the defect width, thereby inhibiting the device from being embolized.
- a closure device can include a delivery /removal mechanism to facilitate device delivery, removal or repositioning.
- a device 70 shown in FIGURES 9A and 9B includes a removal string 72 and a delivery string 74.
- the removal string is movably secured and slides freely inside of the proximal anchor member 76.
- the string extends from one end of the proximal member 76 and is fixed to an opposite end of the distal anchor member 78.
- the strings can, e.g., be sutures or wires such as Nitinol wire.
- FIGURES 9C-E illustrate device deployment using the delivery string 74, which is preferably attached generally to the center of the proximal anchor member 76.
- the delivery sheath 79 containing the device 70 is first inserted between the septum primum and septum secundum into the left atrium as shown in FIGURE 9C.
- the distal anchor 78 is then ejected from the delivery catheter 79.
- Tension is then applied to the delivery string 74, and the delivery sheath is withdrawn into the right atrium and the proximal anchor 76 is ejected.
- FIGURES 9F-H illustrate removal of the device 70.
- tension is applied to the removal string, while the delivery sheath 79 is moved toward the device 70.
- the applied tension causes the proximal anchor 76 to be withdrawn into the delivery sheath as shown in FIGURE 9G.
- the distal anchor 78 is also withdrawn into the delivery sheath as further tension is applied to the removal string.
- the device can then be redeployed if desired or removed.
- the delivery string 74 can be omitted, and the removal string 72 be used for both device deployment and removal.
- the delivery sheath 79 containing the closure device is first inserted between the septum primum and septum secundum into the left atrium in a similar manner to that shown in FIGURE 9C.
- the distal anchor 78 is then ejected from the delivery catheter 79 in a similar manner to that shown in FIGURE 9D.
- Tension is applied to the removal string 72, and the delivery sheath is withdrawn into the right atrium, and the proximal anchor 76 is ejected.
- strings 80 are attached to both ends of the proximal anchor member 82 of a closure device 84. Both anchor members are flexible and can fold as shown in FIGURE 10A in order to be delivered to or removed from the defect.
- each of the proximal and distal anchor members can include two elements 90 separated by an elastic hinge 92.
- the elastic hinge 92 can facilitate folding of the members as shown in FIGURE 11B.
- the hinge 92 can be molded or made from a material such as, e.g., Nitinol or other shape memory materials, which can be a different material from the elements 90.
- an entire closure device can be made from a single sheet of a material as shown, e.g., in the closure device 100 of FIGURE 12. Two opposite ends of the sheet can be rolled to form the proximal and distal anchor members. Glue or heat bonding can be used to maintain the rolled-up configuration of the anchor members 102, 104.
- one or both anchor members 110, 112 of a closure device 114 can be inflatable.
- the anchor members can be inflated with, e.g., saline or other physiological fluid during or before the delivery of the device.
- a tube 116 can communicate with cavities in the anchor members.
- An inlet 118 can be provided at one of the members for introducing fluid therein.
- a wire 120 such as, e.g., an S-shaped wire, can be provided to comiect the proximal and distal anchor members 122, 124 of a device 126 as shown in FIGURE 14.
- the wire can be used to provide additional clamping force while the device is in a PFO defect.
- Other wire shapes are also possible.
- one or more frame structures can be used as the anchor members of a closure device.
- FIGURE 15 shows a closure device 130 having a frame structure 132.
- FIGURE 16 shows a closure device 136 having frames 138, 139.
- the frames can be, e.g., a metal (e.g., Nitinol wire) or polymer frame.
- FIGURES 17-19 illustrate closure devices in accordance with some further embodiments of the invention.
- a closure device 140 shown in FIGURE 17 includes anchor members 142, 144 having a frame structure.
- the frame shape can be polygonal as shown in the figure or it can alternatively be a circular shape. Other frame shapes are also possible as, e.g., will be described below with respect to FIGURES 22-24.
- a recovery suture can be attached to opposite ends of the proximate anchor member 142 to collapse the anchors for delivery in a catheter 146 as shown in FIGURE 18 or for retrieval or repositioning.
- the anchor members can be made from a metal, preferably Nitinol, or polymers.
- an anchor member 148 can include both metal and polymer components.
- the distal and proximal anchors can be formed of a flat sheet-like member rolled to form a cylindrical shape as shown, e.g., in the device 170 of FIGURE 20A.
- the anchors 172, 174 can unroll to form sheet-like members when deployed as shown generally in FIGURE 20B.
- the sheet-like member can be made of a material having shape memory properties such as, e.g., shape memory polymeric materials.
- the sheet-like member can include metal struts made of shape memory metals such as, e.g., Nitinol or Nitinol alloys.
- the shape memory materials allow the device to be delivered in a delivery sheath or catheter with the anchors in the rolled configuration of FIGURE 20A.
- the anchors attain the sheet-like geometry of FIGURE 20B once deployed due to their shape memory properties.
- the anchor members 172, 174 can be connected to each other with a connecting member 176, which can, e.g., be a suture similar to that used in the FIGURE 2 device.
- FIGURES 21A and 21B illustrate a closure device 180 having rolled anchor members 182, 184, which are similar to the anchor members 172, 174 of the device of FIGURES 20A and 20B.
- the anchors 182, 184 are connected to each other by a connecting member or joint 186, which can be a sheet of flexible material similar to the connecting members previously described with respect to FIGURES 6 and 7.
- FIGURE 22A illustrates a closure device 200 in accordance with one or more further embodiments of the invention.
- the device 200 includes distal and proximal anchor members 202, 204, each of which has a polygonal or circular frame structure.
- the anchor members are connected by a connecting member 206, which can be made from a flexible material similar to that previously described in connection with FIGURES 6 and 7.
- the connecting member 206 can be made of two sheets of flexible material connected at their centers, generally forming an "X" shape in the side view of the device.
- the proximal anchor member 204 can include one or more recovery wires or sutures attached to the frame structure for use in device deployment of recovery.
- FIGURE 22C illustrates the device 200 as deployed.
- FIGURES 23 and 24 illustrate closure devices 220, 230, respectively, in accordance with further embodiments of the invention.
- Each device 220, 230 includes distal and proximal anchor members having a frame structure.
- the anchor members are connected by a flexible joint 222, which can be made from a flexible material similar to that previously described in connection with FIGURES 6 and 7.
- the FIGURE 23 device 220 includes distal and proximal anchor members 224, 226 generally having a "+" shape.
- the FIGURE 24 device 230 includes distal and proximal anchor members 232, 234 generally having a "G" shape.
- closure devices described herein can optionally be used along with suturing or stapling techniques where the anchors or flexible joints of the devices can be sewn or stapled to septum primum or secundum for better dislodgment resistance.
- the flexible joint can, if desired, be covered with biocompatible glue to adhere to the tissue or can be loaded with drugs or growth factors to promote healing.
- the glue and also certain drugs can also optionally be stored in any cavities in the anchor members (e.g., in the cylindrical members of FIGURES 6 and 7) and released after deployment.
- Noble metal markers can also be attached to the closure devices for a better x ⁇ ray visualization.
- the various closure devices described herein can include a number of advantageous features.
- the closure devices preferably have an atraumatic shape to reduce trauma during deployment or removal.
- the devices can be self-orienting for ease of deployment.
- the devices because of the flexible center joint, the devices generally conform to the anatomy instead of the anatomy conforming to the devices, which is especially useful in long tunnel defects.
- the devices can preferably be repositioned or/and removed during delivery.
- the devices also generally have a relatively small profile after deployment.
- the flexible center joint of the devices can encourage faster tissue ingrowth and therefore, faster defect closure.
- the devices can also advantageously include bioresorbable components, which can disappear over time.
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002360695A AU2002360695A1 (en) | 2001-12-19 | 2002-12-19 | Septal occluder and associated methods |
EP02795975A EP1467661A4 (en) | 2001-12-19 | 2002-12-19 | Septal occluder and associated methods |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34085801P | 2001-12-19 | 2001-12-19 | |
US60/340,858 | 2001-12-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003053493A2 true WO2003053493A2 (en) | 2003-07-03 |
WO2003053493A3 WO2003053493A3 (en) | 2003-11-06 |
Family
ID=23335225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/040850 WO2003053493A2 (en) | 2001-12-19 | 2002-12-19 | Septal occluder and associated methods |
Country Status (4)
Country | Link |
---|---|
US (2) | US7867250B2 (en) |
EP (1) | EP1467661A4 (en) |
AU (1) | AU2002360695A1 (en) |
WO (1) | WO2003053493A2 (en) |
Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004087235A2 (en) | 2003-03-27 | 2004-10-14 | Cierra, Inc. | Methods and apparatus for treatment of patent foramen ovale |
WO2005027752A1 (en) * | 2003-09-12 | 2005-03-31 | Nmt Medical, Inc. | Pfo closure device with flexible thrombogenic joint and improved dislodgement resistance |
WO2005032335A2 (en) | 2003-09-23 | 2005-04-14 | Cardia, Inc. | Right retrieval mechanism |
US7914527B2 (en) | 2003-03-27 | 2011-03-29 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US7922716B2 (en) | 2003-03-27 | 2011-04-12 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
US7972330B2 (en) | 2003-03-27 | 2011-07-05 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US8021362B2 (en) | 2003-03-27 | 2011-09-20 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US8052678B2 (en) | 2003-03-27 | 2011-11-08 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8109274B2 (en) | 2005-04-11 | 2012-02-07 | Terumo Kabushiki Kaisha | Methods and electrode apparatus to achieve a closure of a layered tissue defect |
US8133221B2 (en) | 2004-06-21 | 2012-03-13 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
US8568447B2 (en) | 2004-05-06 | 2013-10-29 | W.L. Gore & Associates, Inc. | Delivery systems and methods for PFO closure device with two anchors |
US8568431B2 (en) | 2004-03-03 | 2013-10-29 | W.L. Gore & Associates, Inc. | Delivery/recovery system for septal occluder |
US9005242B2 (en) | 2007-04-05 | 2015-04-14 | W.L. Gore & Associates, Inc. | Septal closure device with centering mechanism |
US9017373B2 (en) | 2002-12-09 | 2015-04-28 | W.L. Gore & Associates, Inc. | Septal closure devices |
US9028527B2 (en) | 2002-06-05 | 2015-05-12 | W.L. Gore & Associates, Inc. | Patent foramen ovale (PFO) closure device with radial and circumferential support |
US9078630B2 (en) | 2001-06-01 | 2015-07-14 | St. Jude Medical, Cardiology Division, Inc. | Closure devices, related delivery methods and tools, and related methods of use |
US9084603B2 (en) | 2005-12-22 | 2015-07-21 | W.L. Gore & Associates, Inc. | Catch members for occluder devices |
US9149263B2 (en) | 2003-07-14 | 2015-10-06 | W. L. Gore & Associates, Inc. | Tubular patent foramen ovale (PFO) closure device with catch system |
US9241695B2 (en) | 2002-03-25 | 2016-01-26 | W.L. Gore & Associates, Inc. | Patent foramen ovale (PFO) closure clips |
US9326759B2 (en) | 2003-07-14 | 2016-05-03 | W.L. Gore & Associates, Inc. | Tubular patent foramen ovale (PFO) closure device with catch system |
US9474517B2 (en) | 2008-03-07 | 2016-10-25 | W. L. Gore & Associates, Inc. | Heart occlusion devices |
US9770232B2 (en) | 2011-08-12 | 2017-09-26 | W. L. Gore & Associates, Inc. | Heart occlusion devices |
US9808230B2 (en) | 2014-06-06 | 2017-11-07 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US9861346B2 (en) | 2003-07-14 | 2018-01-09 | W. L. Gore & Associates, Inc. | Patent foramen ovale (PFO) closure device with linearly elongating petals |
US10792025B2 (en) | 2009-06-22 | 2020-10-06 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US10806437B2 (en) | 2009-06-22 | 2020-10-20 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US10828019B2 (en) | 2013-01-18 | 2020-11-10 | W.L. Gore & Associates, Inc. | Sealing device and delivery system |
Families Citing this family (108)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6482224B1 (en) | 1996-08-22 | 2002-11-19 | The Trustees Of Columbia University In The City Of New York | Endovascular flexible stapling device |
US7942888B2 (en) * | 1999-09-13 | 2011-05-17 | Rex Medical, L.P. | Vascular hole closure device |
US6440152B1 (en) * | 2000-07-28 | 2002-08-27 | Microvena Corporation | Defect occluder release assembly and method |
US20050222489A1 (en) * | 2003-10-01 | 2005-10-06 | Ample Medical, Inc. | Devices, systems, and methods for reshaping a heart valve annulus, including the use of a bridge implant |
US7288105B2 (en) | 2001-08-01 | 2007-10-30 | Ev3 Endovascular, Inc. | Tissue opening occluder |
US6776784B2 (en) | 2001-09-06 | 2004-08-17 | Core Medical, Inc. | Clip apparatus for closing septal defects and methods of use |
US20060052821A1 (en) | 2001-09-06 | 2006-03-09 | Ovalis, Inc. | Systems and methods for treating septal defects |
US6702835B2 (en) | 2001-09-07 | 2004-03-09 | Core Medical, Inc. | Needle apparatus for closing septal defects and methods for using such apparatus |
WO2003053493A2 (en) * | 2001-12-19 | 2003-07-03 | Nmt Medical, Inc. | Septal occluder and associated methods |
US9155544B2 (en) * | 2002-03-20 | 2015-10-13 | P Tech, Llc | Robotic systems and methods |
US7976564B2 (en) | 2002-05-06 | 2011-07-12 | St. Jude Medical, Cardiology Division, Inc. | PFO closure devices and related methods of use |
JP2005528162A (en) | 2002-06-03 | 2005-09-22 | エヌエムティー メディカル インコーポレイテッド | Device with biological tissue scaffold for intracardiac defect occlusion |
WO2004037333A1 (en) | 2002-10-25 | 2004-05-06 | Nmt Medical, Inc. | Expandable sheath tubing |
WO2004069055A2 (en) * | 2003-02-04 | 2004-08-19 | Ev3 Sunnyvale Inc. | Patent foramen ovale closure system |
US7658747B2 (en) | 2003-03-12 | 2010-02-09 | Nmt Medical, Inc. | Medical device for manipulation of a medical implant |
US7165552B2 (en) | 2003-03-27 | 2007-01-23 | Cierra, Inc. | Methods and apparatus for treatment of patent foramen ovale |
US20040267306A1 (en) | 2003-04-11 | 2004-12-30 | Velocimed, L.L.C. | Closure devices, related delivery methods, and related methods of use |
US8372112B2 (en) | 2003-04-11 | 2013-02-12 | St. Jude Medical, Cardiology Division, Inc. | Closure devices, related delivery methods, and related methods of use |
EP1648340B1 (en) | 2003-05-19 | 2010-03-03 | SeptRx, Inc. | Tissue distention device and related methods for therapeutic intervention |
DE602004017750D1 (en) | 2003-08-19 | 2008-12-24 | Nmt Medical Inc | Expandable lock hose |
JP2007527272A (en) * | 2003-10-10 | 2007-09-27 | コヒーレックス メディカル インコーポレイテッド | Patent foramen ovale (PFO) closure device, delivery device, and related methods and systems |
US7056286B2 (en) | 2003-11-12 | 2006-06-06 | Adrian Ravenscroft | Medical device anchor and delivery system |
US20050273119A1 (en) | 2003-12-09 | 2005-12-08 | Nmt Medical, Inc. | Double spiral patent foramen ovale closure clamp |
US20050192626A1 (en) | 2004-01-30 | 2005-09-01 | Nmt Medical, Inc. | Devices, systems, and methods for closure of cardiac openings |
US20050203550A1 (en) * | 2004-03-11 | 2005-09-15 | Laufer Michael D. | Surgical fastener |
US20050267524A1 (en) | 2004-04-09 | 2005-12-01 | Nmt Medical, Inc. | Split ends closure device |
US8361110B2 (en) * | 2004-04-26 | 2013-01-29 | W.L. Gore & Associates, Inc. | Heart-shaped PFO closure device |
US7842053B2 (en) | 2004-05-06 | 2010-11-30 | Nmt Medical, Inc. | Double coil occluder |
US7704268B2 (en) | 2004-05-07 | 2010-04-27 | Nmt Medical, Inc. | Closure device with hinges |
JP2007535997A (en) | 2004-05-07 | 2007-12-13 | エヌエムティー メディカル, インコーポレイティッド | Capturing mechanism of tubular septal occluder |
WO2006036837A2 (en) | 2004-09-24 | 2006-04-06 | Nmt Medical, Inc. | Occluder device double securement system for delivery/recovery of such occluder device |
JP4418785B2 (en) * | 2004-09-29 | 2010-02-24 | テルモ株式会社 | Patent application for patent foramen ovale and instrument for patent foramen ovale |
US20060149312A1 (en) * | 2004-12-30 | 2006-07-06 | Edward Arguello | Distal protection device with improved wall apposition |
US20060241687A1 (en) * | 2005-03-16 | 2006-10-26 | Glaser Erik N | Septal occluder with pivot arms and articulating joints |
US20060217760A1 (en) * | 2005-03-17 | 2006-09-28 | Widomski David R | Multi-strand septal occluder |
EP1868507A1 (en) | 2005-03-18 | 2007-12-26 | NMT Medical, Inc. | Catch member for pfo occluder |
US8372113B2 (en) * | 2005-03-24 | 2013-02-12 | W.L. Gore & Associates, Inc. | Curved arm intracardiac occluder |
WO2006130836A2 (en) | 2005-06-02 | 2006-12-07 | Cordis Corporation | Patent foramen ovale closure device |
US8579936B2 (en) | 2005-07-05 | 2013-11-12 | ProMed, Inc. | Centering of delivery devices with respect to a septal defect |
US7766906B2 (en) * | 2005-08-19 | 2010-08-03 | Boston Scientific Scimed, Inc. | Occlusion apparatus |
US8062309B2 (en) * | 2005-08-19 | 2011-11-22 | Boston Scientific Scimed, Inc. | Defect occlusion apparatus, system, and method |
US7837619B2 (en) * | 2005-08-19 | 2010-11-23 | Boston Scientific Scimed, Inc. | Transeptal apparatus, system, and method |
US7998095B2 (en) * | 2005-08-19 | 2011-08-16 | Boston Scientific Scimed, Inc. | Occlusion device |
US7824397B2 (en) * | 2005-08-19 | 2010-11-02 | Boston Scientific Scimed, Inc. | Occlusion apparatus |
US7846179B2 (en) | 2005-09-01 | 2010-12-07 | Ovalis, Inc. | Suture-based systems and methods for treating septal defects |
WO2007028092A1 (en) | 2005-09-01 | 2007-03-08 | Cordis Corporation | Patent foramen ovale closure method |
WO2007030433A2 (en) | 2005-09-06 | 2007-03-15 | Nmt Medical, Inc. | Removable intracardiac rf device |
US9259267B2 (en) | 2005-09-06 | 2016-02-16 | W.L. Gore & Associates, Inc. | Devices and methods for treating cardiac tissue |
CN101049266B (en) * | 2006-04-03 | 2010-11-17 | 孟坚 | Medical use obstruction appliance, and manufacturing method |
JP2009532125A (en) | 2006-03-31 | 2009-09-10 | エヌエムティー メディカル, インコーポレイティッド | Deformable flap catch mechanism for occluder equipment |
US8551135B2 (en) | 2006-03-31 | 2013-10-08 | W.L. Gore & Associates, Inc. | Screw catch mechanism for PFO occluder and method of use |
US8870913B2 (en) | 2006-03-31 | 2014-10-28 | W.L. Gore & Associates, Inc. | Catch system with locking cap for patent foramen ovale (PFO) occluder |
CN101049269B (en) * | 2006-04-03 | 2010-12-29 | 孟坚 | Medical use obstruction appliance |
CN101049268B (en) * | 2006-04-03 | 2011-09-14 | 孟坚 | Medical use obstruction appliance |
US8864809B2 (en) | 2006-08-09 | 2014-10-21 | Coherex Medical, Inc. | Systems and devices for reducing the size of an internal tissue opening |
US9220487B2 (en) * | 2006-08-09 | 2015-12-29 | Coherex Medical, Inc. | Devices for reducing the size of an internal tissue opening |
US8529597B2 (en) | 2006-08-09 | 2013-09-10 | Coherex Medical, Inc. | Devices for reducing the size of an internal tissue opening |
WO2008036384A2 (en) * | 2006-09-21 | 2008-03-27 | Synecor, Llc | Stomach wall closure devices |
US8166978B2 (en) * | 2006-10-04 | 2012-05-01 | Ethicon Endo-Surgery, Inc. | Methods and systems for manipulating tissue |
DE102006050385A1 (en) * | 2006-10-05 | 2008-04-10 | pfm Produkte für die Medizin AG | Implantable mechanism for use in human and/or animal body for e.g. closing atrium septum defect, has partial piece that is folded back on another partial piece from primary form into secondary form of carrying structure |
US9232997B2 (en) | 2006-11-07 | 2016-01-12 | Corvia Medical, Inc. | Devices and methods for retrievable intra-atrial implants |
US10413284B2 (en) | 2006-11-07 | 2019-09-17 | Corvia Medical, Inc. | Atrial pressure regulation with control, sensing, monitoring and therapy delivery |
US8460372B2 (en) | 2006-11-07 | 2013-06-11 | Dc Devices, Inc. | Prosthesis for reducing intra-cardiac pressure having an embolic filter |
US20110257723A1 (en) | 2006-11-07 | 2011-10-20 | Dc Devices, Inc. | Devices and methods for coronary sinus pressure relief |
US10624621B2 (en) | 2006-11-07 | 2020-04-21 | Corvia Medical, Inc. | Devices and methods for the treatment of heart failure |
DE102006054218A1 (en) * | 2006-11-15 | 2008-05-21 | Karl Storz Medizinische Nähsysteme GmbH & Co. KG | Surgical instrument e.g. endoscope, for occluding incision into human body, has occluder that is moved for occluding incision using guidance wire from guidance channel, which is work channel of endoscope |
JP4246233B2 (en) * | 2006-12-21 | 2009-04-02 | オリンパスメディカルシステムズ株式会社 | Visceral anastomosis marker and marker placement device |
WO2008094706A2 (en) | 2007-02-01 | 2008-08-07 | Cook Incorporated | Closure device and method of closing a bodily opening |
US8617205B2 (en) | 2007-02-01 | 2013-12-31 | Cook Medical Technologies Llc | Closure device |
WO2008094691A2 (en) * | 2007-02-01 | 2008-08-07 | Cook Incorporated | Closure device and method for occluding a bodily passageway |
US20080188892A1 (en) * | 2007-02-01 | 2008-08-07 | Cook Incorporated | Vascular occlusion device |
WO2008131167A1 (en) | 2007-04-18 | 2008-10-30 | Nmt Medical, Inc. | Flexible catheter system |
US8734483B2 (en) * | 2007-08-27 | 2014-05-27 | Cook Medical Technologies Llc | Spider PFO closure device |
US8025495B2 (en) * | 2007-08-27 | 2011-09-27 | Cook Medical Technologies Llc | Apparatus and method for making a spider occlusion device |
US8308752B2 (en) * | 2007-08-27 | 2012-11-13 | Cook Medical Technologies Llc | Barrel occlusion device |
US20090062838A1 (en) * | 2007-08-27 | 2009-03-05 | Cook Incorporated | Spider device with occlusive barrier |
US20090118745A1 (en) * | 2007-11-06 | 2009-05-07 | Cook Incorporated | Patent foramen ovale closure apparatus and method |
US8920463B2 (en) | 2008-02-15 | 2014-12-30 | Rex Medical, L.P. | Vascular hole closure device |
US8070772B2 (en) * | 2008-02-15 | 2011-12-06 | Rex Medical, L.P. | Vascular hole closure device |
US9226738B2 (en) | 2008-02-15 | 2016-01-05 | Rex Medical, L.P. | Vascular hole closure delivery device |
US8920462B2 (en) | 2008-02-15 | 2014-12-30 | Rex Medical, L.P. | Vascular hole closure device |
US8491629B2 (en) | 2008-02-15 | 2013-07-23 | Rex Medical | Vascular hole closure delivery device |
US20110029013A1 (en) | 2008-02-15 | 2011-02-03 | Mcguckin James F | Vascular Hole Closure Device |
US9138213B2 (en) * | 2008-03-07 | 2015-09-22 | W.L. Gore & Associates, Inc. | Heart occlusion devices |
US9119607B2 (en) | 2008-03-07 | 2015-09-01 | Gore Enterprise Holdings, Inc. | Heart occlusion devices |
WO2009121001A1 (en) * | 2008-03-28 | 2009-10-01 | Coherex Medical, Inc. | Delivery systems for a medical device and related methods |
US20210161637A1 (en) * | 2009-05-04 | 2021-06-03 | V-Wave Ltd. | Shunt for redistributing atrial blood volume |
US20230285133A1 (en) * | 2009-05-04 | 2023-09-14 | V-Wave Ltd. | Shunt for redistributing atrial blood volume |
WO2010139771A2 (en) * | 2009-06-03 | 2010-12-09 | Symetis Sa | Closure device and methods and systems for using same |
US9050078B2 (en) * | 2009-06-21 | 2015-06-09 | Aesthetics Point Ltd. | Implanted medical device useful for cosmetic surgery |
US9757107B2 (en) | 2009-09-04 | 2017-09-12 | Corvia Medical, Inc. | Methods and devices for intra-atrial shunts having adjustable sizes |
EP2496189A4 (en) | 2009-11-04 | 2016-05-11 | Nitinol Devices And Components Inc | Alternating circumferential bridge stent design and methods for use thereof |
US9649211B2 (en) | 2009-11-04 | 2017-05-16 | Confluent Medical Technologies, Inc. | Alternating circumferential bridge stent design and methods for use thereof |
EP2528646A4 (en) | 2010-01-29 | 2017-06-28 | DC Devices, Inc. | Devices and systems for treating heart failure |
CA2785041A1 (en) | 2010-01-29 | 2011-08-04 | Dc Devices, Inc. | Devices and methods for reducing venous pressure |
EP2627265B8 (en) | 2010-10-15 | 2019-02-20 | Cook Medical Technologies LLC | Occlusion device for blocking fluid flow through bodily passages |
EP2673038B1 (en) | 2011-02-10 | 2017-07-19 | Corvia Medical, Inc. | Apparatus to create and maintain an intra-atrial pressure relief opening |
US8591543B2 (en) * | 2011-04-28 | 2013-11-26 | Cardiotulip Llc | Devices and methods for closure of a patent foramen ovale |
WO2013096965A1 (en) | 2011-12-22 | 2013-06-27 | Dc Devices, Inc. | Methods and devices for intra-atrial devices having selectable flow rates |
US9005155B2 (en) | 2012-02-03 | 2015-04-14 | Dc Devices, Inc. | Devices and methods for treating heart failure |
US10940167B2 (en) | 2012-02-10 | 2021-03-09 | Cvdevices, Llc | Methods and uses of biological tissues for various stent and other medical applications |
US10588611B2 (en) | 2012-04-19 | 2020-03-17 | Corvia Medical Inc. | Implant retention attachment and method of use |
US9649480B2 (en) | 2012-07-06 | 2017-05-16 | Corvia Medical, Inc. | Devices and methods of treating or ameliorating diastolic heart failure through pulmonary valve intervention |
AU2014214700B2 (en) | 2013-02-11 | 2018-01-18 | Cook Medical Technologies Llc | Expandable support frame and medical device |
US9775636B2 (en) | 2013-03-12 | 2017-10-03 | Corvia Medical, Inc. | Devices, systems, and methods for treating heart failure |
US10675450B2 (en) | 2014-03-12 | 2020-06-09 | Corvia Medical, Inc. | Devices and methods for treating heart failure |
JP6799526B2 (en) | 2014-07-23 | 2020-12-16 | コルヴィア メディカル インコーポレイテッド | Equipment and methods for the treatment of heart failure |
US11504105B2 (en) | 2019-01-25 | 2022-11-22 | Rex Medical L.P. | Vascular hole closure device |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5810884A (en) * | 1996-09-09 | 1998-09-22 | Beth Israel Deaconess Medical Center | Apparatus and method for closing a vascular perforation after percutaneous puncture of a blood vessel in a living subject |
US5861003A (en) * | 1996-10-23 | 1999-01-19 | The Cleveland Clinic Foundation | Apparatus and method for occluding a defect or aperture within body surface |
US5976174A (en) * | 1997-12-15 | 1999-11-02 | Ruiz; Carlos E. | Medical hole closure device and methods of use |
US5993475A (en) * | 1998-04-22 | 1999-11-30 | Bristol-Myers Squibb Co. | Tissue repair device |
US6077291A (en) * | 1992-01-21 | 2000-06-20 | Regents Of The University Of Minnesota | Septal defect closure device |
US6113609A (en) * | 1998-05-26 | 2000-09-05 | Scimed Life Systems, Inc. | Implantable tissue fastener and system for treating gastroesophageal reflux disease |
US6206907B1 (en) * | 1999-05-07 | 2001-03-27 | Cardia, Inc. | Occlusion device with stranded wire support arms |
US6214029B1 (en) * | 2000-04-26 | 2001-04-10 | Microvena Corporation | Septal defect occluder |
US6379368B1 (en) * | 1999-05-13 | 2002-04-30 | Cardia, Inc. | Occlusion device with non-thrombogenic properties |
US6387104B1 (en) * | 1999-11-12 | 2002-05-14 | Scimed Life Systems, Inc. | Method and apparatus for endoscopic repair of the lower esophageal sphincter |
US6494888B1 (en) * | 1999-06-22 | 2002-12-17 | Ndo Surgical, Inc. | Tissue reconfiguration |
Family Cites Families (245)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1445746A1 (en) | 1964-01-04 | 1969-03-20 | Bayer Ag | Process for the production of asymmetrical thiol or thionothiolphosphoric acid esters |
US3874388A (en) * | 1973-02-12 | 1975-04-01 | Ochsner Med Found Alton | Shunt defect closure system |
US3875648A (en) | 1973-04-04 | 1975-04-08 | Dennison Mfg Co | Fastener attachment apparatus and method |
US3824631A (en) * | 1973-05-11 | 1974-07-23 | Sampson Corp | Bone joint fusion prosthesis |
US3924631A (en) | 1973-12-06 | 1975-12-09 | Altair Inc | Magnetic clamp |
US4006747A (en) | 1975-04-23 | 1977-02-08 | Ethicon, Inc. | Surgical method |
US4007743A (en) * | 1975-10-20 | 1977-02-15 | American Hospital Supply Corporation | Opening mechanism for umbrella-like intravascular shunt defect closure device |
CH598398A5 (en) * | 1976-07-21 | 1978-04-28 | Jura Elektroapparate Fab | |
US4235238A (en) * | 1978-05-11 | 1980-11-25 | Olympus Optical Co., Ltd. | Apparatus for suturing coeliac tissues |
US4425908A (en) | 1981-10-22 | 1984-01-17 | Beth Israel Hospital | Blood clot filter |
JPS6171065A (en) | 1984-09-13 | 1986-04-11 | テルモ株式会社 | Catheter introducer |
US4696300A (en) | 1985-04-11 | 1987-09-29 | Dennison Manufacturing Company | Fastener for joining materials |
US4626245A (en) | 1985-08-30 | 1986-12-02 | Cordis Corporation | Hemostatis valve comprising an elastomeric partition having opposed intersecting slits |
US4710192A (en) | 1985-12-30 | 1987-12-01 | Liotta Domingo S | Diaphragm and method for occlusion of the descending thoracic aorta |
EP0253365B1 (en) * | 1986-07-16 | 1991-11-27 | Sumitomo Chemical Company, Limited | Rubber composition |
US4852568A (en) * | 1987-02-17 | 1989-08-01 | Kensey Nash Corporation | Method and apparatus for sealing an opening in tissue of a living being |
US5478353A (en) | 1987-05-14 | 1995-12-26 | Yoon; Inbae | Suture tie device system and method for suturing anatomical tissue proximate an opening |
US5245023A (en) | 1987-06-29 | 1993-09-14 | Massachusetts Institute Of Technology | Method for producing novel polyester biopolymers |
US5250430A (en) | 1987-06-29 | 1993-10-05 | Massachusetts Institute Of Technology | Polyhydroxyalkanoate polymerase |
US4836204A (en) * | 1987-07-06 | 1989-06-06 | Landymore Roderick W | Method for effecting closure of a perforation in the septum of the heart |
US4840623A (en) * | 1988-02-01 | 1989-06-20 | Fbk International Corporation | Medical catheter with splined internal wall |
IT1216042B (en) | 1988-03-09 | 1990-02-22 | Carlo Rebuffat | AUTOMATIC TOOL FOR TOBACCO BAG SUTURES FOR SURGICAL USE. |
US4956178A (en) | 1988-07-11 | 1990-09-11 | Purdue Research Foundation | Tissue graft composition |
US4902508A (en) * | 1988-07-11 | 1990-02-20 | Purdue Research Foundation | Tissue graft composition |
US4917089A (en) * | 1988-08-29 | 1990-04-17 | Sideris Eleftherios B | Buttoned device for the transvenous occlusion of intracardiac defects |
FR2641692A1 (en) * | 1989-01-17 | 1990-07-20 | Nippon Zeon Co | Plug for closing an opening for a medical application, and device for the closure plug making use thereof |
US5245080A (en) | 1989-02-20 | 1993-09-14 | Jouveinal Sa | (+)-1-[(3,4,5-trimethoxy)-benzyloxymethyl]-1-phenyl-N,N-dimethyl-N-propylamine, process for preparing it and its therapeutical use |
US5620461A (en) * | 1989-05-29 | 1997-04-15 | Muijs Van De Moer; Wouter M. | Sealing device |
US5149327A (en) | 1989-09-05 | 1992-09-22 | Terumo Kabushiki Kaisha | Medical valve, catheter with valve, and catheter assembly |
US5226879A (en) * | 1990-03-01 | 1993-07-13 | William D. Ensminger | Implantable access device |
DE69102515T2 (en) | 1990-04-02 | 1994-10-20 | Kanji Inoue | DEVICE FOR CLOSING A SHUTTER OPENING BY MEANS OF A NON-OPERATIONAL METHOD. |
US5078736A (en) * | 1990-05-04 | 1992-01-07 | Interventional Thermodynamics, Inc. | Method and apparatus for maintaining patency in the body passages |
US5021059A (en) * | 1990-05-07 | 1991-06-04 | Kensey Nash Corporation | Plug device with pulley for sealing punctures in tissue and methods of use |
US5037433A (en) | 1990-05-17 | 1991-08-06 | Wilk Peter J | Endoscopic suturing device and related method and suture |
US20020032459A1 (en) * | 1990-06-20 | 2002-03-14 | Danforth Biomedical, Inc. | Radially-expandable tubular elements for use in the construction of medical devices |
US5041129A (en) | 1990-07-02 | 1991-08-20 | Acufex Microsurgical, Inc. | Slotted suture anchor and method of anchoring a suture |
US5269809A (en) * | 1990-07-02 | 1993-12-14 | American Cyanamid Company | Locking mechanism for use with a slotted suture anchor |
JP3256540B2 (en) | 1990-10-09 | 2002-02-12 | メッドトロニック・インコーポレイテッド | Device or device for manipulating the target object |
JPH04170966A (en) | 1990-11-01 | 1992-06-18 | Nippon Sherwood Kk | Valvular body for catheter introducer blood stop valve |
US5108420A (en) * | 1991-02-01 | 1992-04-28 | Temple University | Aperture occlusion device |
SE510232C2 (en) * | 1991-03-06 | 1999-05-03 | Stretchex Ab | Surgical stretching device for tissue expansion |
US5257637A (en) | 1991-03-22 | 1993-11-02 | El Gazayerli Mohamed M | Method for suture knot placement and tying |
CA2078530A1 (en) * | 1991-09-23 | 1993-03-24 | Jay Erlebacher | Percutaneous arterial puncture seal device and insertion tool therefore |
CA2082090C (en) * | 1991-11-05 | 2004-04-27 | Jack Fagan | Improved occluder for repair of cardiac and vascular defects |
DE69229539T2 (en) | 1991-11-05 | 2000-02-17 | Childrens Medical Center | Occlusion device for repairing heart and vascular defects |
US5411520A (en) * | 1991-11-08 | 1995-05-02 | Kensey Nash Corporation | Hemostatic vessel puncture closure system utilizing a plug located within the puncture tract spaced from the vessel, and method of use |
US5222974A (en) * | 1991-11-08 | 1993-06-29 | Kensey Nash Corporation | Hemostatic puncture closure system and method of use |
US5282827A (en) * | 1991-11-08 | 1994-02-01 | Kensey Nash Corporation | Hemostatic puncture closure system and method of use |
US5649950A (en) * | 1992-01-22 | 1997-07-22 | C. R. Bard | System for the percutaneous transluminal front-end loading delivery and retrieval of a prosthetic occluder |
US5316262A (en) * | 1992-01-31 | 1994-05-31 | Suprex Corporation | Fluid restrictor apparatus and method for making the same |
US5167363A (en) | 1992-02-10 | 1992-12-01 | Adkinson Steven S | Collapsible storage pen |
US5411481A (en) | 1992-04-08 | 1995-05-02 | American Cyanamid Co. | Surgical purse string suturing instrument and method |
US5236440A (en) | 1992-04-14 | 1993-08-17 | American Cyanamid Company | Surgical fastener |
US5540712A (en) | 1992-05-01 | 1996-07-30 | Nitinol Medical Technologies, Inc. | Stent and method and apparatus for forming and delivering the same |
US5354308A (en) | 1992-05-01 | 1994-10-11 | Beth Israel Hospital Association | Metal wire stent |
DE4215449C1 (en) | 1992-05-11 | 1993-09-02 | Ethicon Gmbh & Co Kg, 2000 Norderstedt, De | |
US5312341A (en) * | 1992-08-14 | 1994-05-17 | Wayne State University | Retaining apparatus and procedure for transseptal catheterization |
US5304184A (en) | 1992-10-19 | 1994-04-19 | Indiana University Foundation | Apparatus and method for positive closure of an internal tissue membrane opening |
US5275826A (en) * | 1992-11-13 | 1994-01-04 | Purdue Research Foundation | Fluidized intestinal submucosa and its use as an injectable tissue graft |
US5417699A (en) | 1992-12-10 | 1995-05-23 | Perclose Incorporated | Device and method for the percutaneous suturing of a vascular puncture site |
US5284488A (en) * | 1992-12-23 | 1994-02-08 | Sideris Eleftherios B | Adjustable devices for the occlusion of cardiac defects |
US6346074B1 (en) | 1993-02-22 | 2002-02-12 | Heartport, Inc. | Devices for less invasive intracardiac interventions |
US5797960A (en) | 1993-02-22 | 1998-08-25 | Stevens; John H. | Method and apparatus for thoracoscopic intracardiac procedures |
US5312435A (en) * | 1993-05-17 | 1994-05-17 | Kensey Nash Corporation | Fail predictable, reinforced anchor for hemostatic puncture closure |
US5350363A (en) | 1993-06-14 | 1994-09-27 | Cordis Corporation | Enhanced sheath valve |
CA2124651C (en) * | 1993-08-20 | 2004-09-28 | David T. Green | Apparatus and method for applying and adjusting an anchoring device |
ATE283916T1 (en) * | 1993-09-20 | 2004-12-15 | Novartis Pharma Gmbh | HUMAN METABOTROPIC GLUTAMA RECEPTOR SUBTYPE HMGLUR7 AND RELATED DNA COMPOUNDS |
US5480424A (en) * | 1993-11-01 | 1996-01-02 | Cox; James L. | Heart valve replacement using flexible tubes |
JP3185906B2 (en) * | 1993-11-26 | 2001-07-11 | ニプロ株式会社 | Prosthesis for atrial septal defect |
US5618314A (en) * | 1993-12-13 | 1997-04-08 | Harwin; Steven F. | Suture anchor device |
US6334872B1 (en) | 1994-02-18 | 2002-01-01 | Organogenesis Inc. | Method for treating diseased or damaged organs |
AU2255195A (en) | 1994-04-06 | 1995-10-30 | William Cook Europe A/S | A medical article for implantation into the vascular system of a patient |
US5853420A (en) | 1994-04-21 | 1998-12-29 | B. Braun Celsa | Assembly comprising a blood filter for temporary or definitive use and device for implanting it, corresponding filter and method of implanting such a filter |
ATE310839T1 (en) | 1994-04-29 | 2005-12-15 | Scimed Life Systems Inc | STENT WITH COLLAGEN |
US6475232B1 (en) | 1996-12-10 | 2002-11-05 | Purdue Research Foundation | Stent with reduced thrombogenicity |
US5601571A (en) | 1994-05-17 | 1997-02-11 | Moss; Gerald | Surgical fastener implantation device |
US5470337A (en) * | 1994-05-17 | 1995-11-28 | Moss; Gerald | Surgical fastener |
US5453095A (en) | 1994-06-07 | 1995-09-26 | Cordis Corporation | One piece self-aligning, self-lubricating catheter valve |
US5725552A (en) * | 1994-07-08 | 1998-03-10 | Aga Medical Corporation | Percutaneous catheter directed intravascular occlusion devices |
US5433727A (en) * | 1994-08-16 | 1995-07-18 | Sideris; Eleftherios B. | Centering buttoned device for the occlusion of large defects for occluding |
DE9413645U1 (en) | 1994-08-24 | 1994-10-27 | Schneidt Bernhard Ing Grad | Device for closing a duct, in particular the ductus arteriosus |
US5577299A (en) | 1994-08-26 | 1996-11-26 | Thompson; Carl W. | Quick-release mechanical knot apparatus |
US5618311A (en) | 1994-09-28 | 1997-04-08 | Gryskiewicz; Joseph M. | Surgical subcuticular fastener system |
US6171329B1 (en) * | 1994-12-19 | 2001-01-09 | Gore Enterprise Holdings, Inc. | Self-expanding defect closure device and method of making and using |
US5879366A (en) * | 1996-12-20 | 1999-03-09 | W.L. Gore & Associates, Inc. | Self-expanding defect closure device and method of making and using |
US5702421A (en) * | 1995-01-11 | 1997-12-30 | Schneidt; Bernhard | Closure device for closing a vascular opening, such as patent ductus arteriosus |
US5480353A (en) * | 1995-02-02 | 1996-01-02 | Garza, Jr.; Ponciano | Shaker crank for a harvester |
US5634936A (en) * | 1995-02-06 | 1997-06-03 | Scimed Life Systems, Inc. | Device for closing a septal defect |
US5649959A (en) * | 1995-02-10 | 1997-07-22 | Sherwood Medical Company | Assembly for sealing a puncture in a vessel |
US5711969A (en) | 1995-04-07 | 1998-01-27 | Purdue Research Foundation | Large area submucosal tissue graft constructs |
US5733337A (en) * | 1995-04-07 | 1998-03-31 | Organogenesis, Inc. | Tissue repair fabric |
US6322548B1 (en) | 1995-05-10 | 2001-11-27 | Eclipse Surgical Technologies | Delivery catheter system for heart chamber |
US6132438A (en) * | 1995-06-07 | 2000-10-17 | Ep Technologies, Inc. | Devices for installing stasis reducing means in body tissue |
IL151563A0 (en) * | 1995-10-13 | 2003-04-10 | Transvascular Inc | A longitudinal compression apparatus for compressing tissue |
DE69612507T2 (en) * | 1995-10-30 | 2001-08-09 | Childrens Medical Center | SELF-CENTERING, SHIELD-LIKE DEVICE FOR CLOSING A SEPTAL DEFECT |
US5717259A (en) * | 1996-01-11 | 1998-02-10 | Schexnayder; J. Rodney | Electromagnetic machine |
DE19604817C2 (en) * | 1996-02-09 | 2003-06-12 | Pfm Prod Fuer Die Med Ag | Device for closing defect openings in the human or animal body |
CA2197614C (en) | 1996-02-20 | 2002-07-02 | Charles S. Taylor | Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft surgery |
US5733294A (en) * | 1996-02-28 | 1998-03-31 | B. Braun Medical, Inc. | Self expanding cardiovascular occlusion device, method of using and method of making the same |
US5853422A (en) | 1996-03-22 | 1998-12-29 | Scimed Life Systems, Inc. | Apparatus and method for closing a septal defect |
US5755791A (en) | 1996-04-05 | 1998-05-26 | Purdue Research Foundation | Perforated submucosal tissue graft constructs |
AR001590A1 (en) | 1996-04-10 | 1997-11-26 | Jorge Alberto Baccaro | Abnormal vascular communications occluder device and applicator cartridge of said device |
US5662681A (en) * | 1996-04-23 | 1997-09-02 | Kensey Nash Corporation | Self locking closure for sealing percutaneous punctures |
US6488706B1 (en) | 1996-05-08 | 2002-12-03 | Carag Ag | Device for plugging an opening such as in a wall of a hollow or tubular organ |
EP0900051A1 (en) * | 1996-05-08 | 1999-03-10 | Salviac Limited | An occluder device |
US5893856A (en) | 1996-06-12 | 1999-04-13 | Mitek Surgical Products, Inc. | Apparatus and method for binding a first layer of material to a second layer of material |
US6143037A (en) | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
US5690674A (en) * | 1996-07-02 | 1997-11-25 | Cordis Corporation | Wound closure with plug |
US5800516A (en) | 1996-08-08 | 1998-09-01 | Cordis Corporation | Deployable and retrievable shape memory stent/tube and method |
US6482224B1 (en) | 1996-08-22 | 2002-11-19 | The Trustees Of Columbia University In The City Of New York | Endovascular flexible stapling device |
US5776183A (en) * | 1996-08-23 | 1998-07-07 | Kanesaka; Nozomu | Expandable stent |
US5741297A (en) * | 1996-08-28 | 1998-04-21 | Simon; Morris | Daisy occluder and method for septal defect repair |
US5944691A (en) | 1996-11-04 | 1999-08-31 | Cordis Corporation | Catheter having an expandable shaft |
JP4676580B2 (en) | 1996-11-05 | 2011-04-27 | パーデュー・リサーチ・ファウンデーション | Myocardial graft composition |
AU736572B2 (en) | 1996-12-10 | 2001-08-02 | Purdue Research Foundation | Artificial vascular valves |
JP4084420B2 (en) | 1996-12-10 | 2008-04-30 | パーデュー・リサーチ・ファウンデーション | Tubular submucosa graft composition |
US6406420B1 (en) * | 1997-01-02 | 2002-06-18 | Myocor, Inc. | Methods and devices for improving cardiac function in hearts |
US5776162A (en) | 1997-01-03 | 1998-07-07 | Nitinol Medical Technologies, Inc. | Vessel implantable shape memory appliance with superelastic hinged joint |
JP3134288B2 (en) * | 1997-01-30 | 2001-02-13 | 株式会社ニッショー | Endocardial suture surgery tool |
JP3134287B2 (en) * | 1997-01-30 | 2001-02-13 | 株式会社ニッショー | Catheter assembly for endocardial suture surgery |
US5993844A (en) | 1997-05-08 | 1999-11-30 | Organogenesis, Inc. | Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix |
US6867248B1 (en) * | 1997-05-12 | 2005-03-15 | Metabolix, Inc. | Polyhydroxyalkanoate compositions having controlled degradation rates |
PT981381E (en) * | 1997-05-12 | 2007-04-30 | Metabolix Inc | Polyhydroxyalkanoates for in vivo applications |
US6610764B1 (en) | 1997-05-12 | 2003-08-26 | Metabolix, Inc. | Polyhydroxyalkanoate compositions having controlled degradation rates |
US6071292A (en) | 1997-06-28 | 2000-06-06 | Transvascular, Inc. | Transluminal methods and devices for closing, forming attachments to, and/or forming anastomotic junctions in, luminal anatomical structures |
US6030007A (en) * | 1997-07-07 | 2000-02-29 | Hughes Electronics Corporation | Continually adjustable nonreturn knot |
US5928260A (en) * | 1997-07-10 | 1999-07-27 | Scimed Life Systems, Inc. | Removable occlusion system for aneurysm neck |
US6071998A (en) * | 1997-07-22 | 2000-06-06 | Metabolix, Inc. | Polyhydroxyalkanoate molding compositions |
US6828357B1 (en) | 1997-07-31 | 2004-12-07 | Metabolix, Inc. | Polyhydroxyalkanoate compositions having controlled degradation rates |
US6174330B1 (en) * | 1997-08-01 | 2001-01-16 | Schneider (Usa) Inc | Bioabsorbable marker having radiopaque constituents |
US6174322B1 (en) * | 1997-08-08 | 2001-01-16 | Cardia, Inc. | Occlusion device for the closure of a physical anomaly such as a vascular aperture or an aperture in a septum |
US6077880A (en) * | 1997-08-08 | 2000-06-20 | Cordis Corporation | Highly radiopaque polyolefins and method for making the same |
JP2001516574A (en) * | 1997-09-19 | 2001-10-02 | メタボリックス,インコーポレイテッド | Biological system for producing polyhydroxyalkanoate polymers containing 4-hydroxy acids |
US5902319A (en) | 1997-09-25 | 1999-05-11 | Daley; Robert J. | Bioabsorbable staples |
US6106913A (en) | 1997-10-10 | 2000-08-22 | Quantum Group, Inc | Fibrous structures containing nanofibrils and other textile fibers |
US5989268A (en) | 1997-10-28 | 1999-11-23 | Boston Scientific Corporation | Endoscopic hemostatic clipping device |
US6045551A (en) * | 1998-02-06 | 2000-04-04 | Bonutti; Peter M. | Bone suture |
JP3799810B2 (en) * | 1998-03-30 | 2006-07-19 | ニプロ株式会社 | Transcatheter surgery closure plug and catheter assembly |
US6113611A (en) * | 1998-05-28 | 2000-09-05 | Advanced Vascular Technologies, Llc | Surgical fastener and delivery system |
US7452371B2 (en) | 1999-06-02 | 2008-11-18 | Cook Incorporated | Implantable vascular device |
US6265333B1 (en) | 1998-06-02 | 2001-07-24 | Board Of Regents, University Of Nebraska-Lincoln | Delamination resistant composites prepared by small diameter fiber reinforcement at ply interfaces |
US6361559B1 (en) | 1998-06-10 | 2002-03-26 | Converge Medical, Inc. | Thermal securing anastomosis systems |
US6328822B1 (en) * | 1998-06-26 | 2001-12-11 | Kiyohito Ishida | Functionally graded alloy, use thereof and method for producing same |
US6165183A (en) | 1998-07-15 | 2000-12-26 | St. Jude Medical, Inc. | Mitral and tricuspid valve repair |
US5919200A (en) * | 1998-10-09 | 1999-07-06 | Hearten Medical, Inc. | Balloon catheter for abrading a patent foramen ovale and method of using the balloon catheter |
US6183496B1 (en) * | 1998-11-02 | 2001-02-06 | Datascope Investment Corp. | Collapsible hemostatic plug |
US7044134B2 (en) | 1999-11-08 | 2006-05-16 | Ev3 Sunnyvale, Inc | Method of implanting a device in the left atrial appendage |
US6152144A (en) | 1998-11-06 | 2000-11-28 | Appriva Medical, Inc. | Method and device for left atrial appendage occlusion |
US7713282B2 (en) | 1998-11-06 | 2010-05-11 | Atritech, Inc. | Detachable atrial appendage occlusion balloon |
JP3906475B2 (en) | 1998-12-22 | 2007-04-18 | ニプロ株式会社 | Transcatheter surgery closure plug and catheter assembly |
US6356782B1 (en) * | 1998-12-24 | 2002-03-12 | Vivant Medical, Inc. | Subcutaneous cavity marking device and method |
US6371904B1 (en) * | 1998-12-24 | 2002-04-16 | Vivant Medical, Inc. | Subcutaneous cavity marking device and method |
US6217590B1 (en) | 1999-01-22 | 2001-04-17 | Scion International, Inc. | Surgical instrument for applying multiple staples and cutting blood vessels and organic structures and method therefor |
US6228097B1 (en) | 1999-01-22 | 2001-05-08 | Scion International, Inc. | Surgical instrument for clipping and cutting blood vessels and organic structures |
CA2363262C (en) * | 1999-03-04 | 2010-09-28 | Tepha, Inc. | Bioabsorbable, biocompatible polymers for tissue engineering |
EP2305324B1 (en) * | 1999-03-25 | 2014-09-17 | Metabolix, Inc. | Medical devices and applications of polyhydroxyalkanoate polymers |
DE69927474T2 (en) | 1999-03-29 | 2006-07-06 | William Cook Europe A/S | A guidewire |
US6277139B1 (en) | 1999-04-01 | 2001-08-21 | Scion Cardio-Vascular, Inc. | Vascular protection and embolic material retriever |
US6277138B1 (en) | 1999-08-17 | 2001-08-21 | Scion Cardio-Vascular, Inc. | Filter for embolic material mounted on expandable frame |
US6379342B1 (en) | 1999-04-02 | 2002-04-30 | Scion International, Inc. | Ampoule for dispensing medication and method of use |
JP2000300571A (en) * | 1999-04-19 | 2000-10-31 | Nissho Corp | Closure plug for transcatheter operation |
US6712836B1 (en) | 1999-05-13 | 2004-03-30 | St. Jude Medical Atg, Inc. | Apparatus and methods for closing septal defects and occluding blood flow |
US6488689B1 (en) | 1999-05-20 | 2002-12-03 | Aaron V. Kaplan | Methods and apparatus for transpericardial left atrial appendage closure |
US6426145B1 (en) | 1999-05-20 | 2002-07-30 | Scimed Life Systems, Inc. | Radiopaque compositions for visualization of medical devices |
US6165204A (en) | 1999-06-11 | 2000-12-26 | Scion International, Inc. | Shaped suture clip, appliance and method therefor |
US7416554B2 (en) * | 2002-12-11 | 2008-08-26 | Usgi Medical Inc | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US6306424B1 (en) | 1999-06-30 | 2001-10-23 | Ethicon, Inc. | Foam composite for the repair or regeneration of tissue |
US6206895B1 (en) | 1999-07-13 | 2001-03-27 | Scion Cardio-Vascular, Inc. | Suture with toggle and delivery system |
US6398796B2 (en) | 1999-07-13 | 2002-06-04 | Scion Cardio-Vascular, Inc. | Suture with toggle and delivery system |
US6245080B1 (en) | 1999-07-13 | 2001-06-12 | Scion Cardio-Vascular, Inc. | Suture with toggle and delivery system |
US7892246B2 (en) | 1999-07-28 | 2011-02-22 | Bioconnect Systems, Inc. | Devices and methods for interconnecting conduits and closing openings in tissue |
US6231561B1 (en) | 1999-09-20 | 2001-05-15 | Appriva Medical, Inc. | Method and apparatus for closing a body lumen |
US6551303B1 (en) * | 1999-10-27 | 2003-04-22 | Atritech, Inc. | Barrier device for ostium of left atrial appendage |
US6371971B1 (en) * | 1999-11-15 | 2002-04-16 | Scimed Life Systems, Inc. | Guidewire filter and methods of use |
US7335426B2 (en) | 1999-11-19 | 2008-02-26 | Advanced Bio Prosthetic Surfaces, Ltd. | High strength vacuum deposited nitinol alloy films and method of making same |
US20010041914A1 (en) | 1999-11-22 | 2001-11-15 | Frazier Andrew G.C. | Tissue patch deployment catheter |
US6790218B2 (en) | 1999-12-23 | 2004-09-14 | Swaminathan Jayaraman | Occlusive coil manufacture and delivery |
DE10000137A1 (en) | 2000-01-04 | 2001-07-12 | Pfm Prod Fuer Die Med Ag | Implantate for closing defect apertures in human or animal bodies, bearing structure of which can be reversed from secondary to primary form by elastic force |
US6780197B2 (en) | 2000-01-05 | 2004-08-24 | Integrated Vascular Systems, Inc. | Apparatus and methods for delivering a vascular closure device to a body lumen |
US20010034567A1 (en) | 2000-01-20 | 2001-10-25 | Allen Marc L. | Remote management of retail petroleum equipment |
FR2804567B1 (en) | 2000-01-31 | 2002-04-12 | St Microelectronics Sa | VIDEO PREAMPLIFIER |
US6227139B1 (en) * | 2000-03-16 | 2001-05-08 | The United States Of America As Represented By The Secretary Of The Navy | Control tab assisted lift reducing system for underwater hydrofoil surface |
US7056294B2 (en) | 2000-04-13 | 2006-06-06 | Ev3 Sunnyvale, Inc | Method and apparatus for accessing the left atrial appendage |
US6786915B2 (en) * | 2000-04-19 | 2004-09-07 | Radi Medical Systems Ab | Reinforced absorbable medical sealing device |
JP3844661B2 (en) | 2000-04-19 | 2006-11-15 | ラディ・メディカル・システムズ・アクチェボラーグ | Intra-arterial embolus |
US6551344B2 (en) | 2000-04-26 | 2003-04-22 | Ev3 Inc. | Septal defect occluder |
US6352552B1 (en) | 2000-05-02 | 2002-03-05 | Scion Cardio-Vascular, Inc. | Stent |
US6599448B1 (en) | 2000-05-10 | 2003-07-29 | Hydromer, Inc. | Radio-opaque polymeric compositions |
US6334864B1 (en) | 2000-05-17 | 2002-01-01 | Aga Medical Corp. | Alignment member for delivering a non-symmetric device with a predefined orientation |
KR20040014389A (en) | 2000-07-21 | 2004-02-14 | 메타볼릭스 인코포레이티드 | Production of polyhydroxyalkanoates from polyols |
US6440152B1 (en) | 2000-07-28 | 2002-08-27 | Microvena Corporation | Defect occluder release assembly and method |
US6867249B2 (en) * | 2000-08-18 | 2005-03-15 | Kin Man Amazon Lee | Lightweight and porous construction materials containing rubber |
AU2001285369A1 (en) | 2000-09-01 | 2002-03-13 | Advanced Vascular Technologies, Llc | Endovascular fastener and grafting apparatus and method |
US6364853B1 (en) | 2000-09-11 | 2002-04-02 | Scion International, Inc. | Irrigation and suction valve and method therefor |
CA2423360A1 (en) | 2000-09-21 | 2002-03-28 | Atritech, Inc. | Apparatus for implanting devices in atrial appendages |
JP3722682B2 (en) * | 2000-09-21 | 2005-11-30 | 富士通株式会社 | Transmission device that automatically changes the type of transmission data within a specific band |
US20020072792A1 (en) * | 2000-09-22 | 2002-06-13 | Robert Burgermeister | Stent with optimal strength and radiopacity characteristics |
US20020052572A1 (en) | 2000-09-25 | 2002-05-02 | Kenneth Franco | Resorbable anastomosis stents and plugs and their use in patients |
US6666861B1 (en) | 2000-10-05 | 2003-12-23 | James R. Grabek | Atrial appendage remodeling device and method |
US6375625B1 (en) | 2000-10-18 | 2002-04-23 | Scion Valley, Inc. | In-line specimen trap and method therefor |
US6629901B2 (en) | 2000-11-09 | 2003-10-07 | Ben Huang | Composite grip for golf clubs |
US6508828B1 (en) * | 2000-11-03 | 2003-01-21 | Radi Medical Systems Ab | Sealing device and wound closure device |
US6746404B2 (en) | 2000-12-18 | 2004-06-08 | Biosense, Inc. | Method for anchoring a medical device between tissue |
US20020128680A1 (en) | 2001-01-25 | 2002-09-12 | Pavlovic Jennifer L. | Distal protection device with electrospun polymer fiber matrix |
US6550480B2 (en) | 2001-01-31 | 2003-04-22 | Numed/Tech Llc | Lumen occluders made from thermodynamic materials |
US20020107531A1 (en) | 2001-02-06 | 2002-08-08 | Schreck Stefan G. | Method and system for tissue repair using dual catheters |
US6623518B2 (en) | 2001-02-26 | 2003-09-23 | Ev3 Peripheral, Inc. | Implant delivery system with interlock |
WO2002071977A2 (en) * | 2001-03-08 | 2002-09-19 | Atritech, Inc. | Atrial filter implants |
US6726696B1 (en) * | 2001-04-24 | 2004-04-27 | Advanced Catheter Engineering, Inc. | Patches and collars for medical applications and methods of use |
US20030004533A1 (en) * | 2001-05-04 | 2003-01-02 | Concentric Medical | Bioactive polymer vaso-occlusive device |
US6921410B2 (en) | 2001-05-29 | 2005-07-26 | Scimed Life Systems, Inc. | Injection molded vaso-occlusive elements |
US6537300B2 (en) | 2001-05-30 | 2003-03-25 | Scimed Life Systems, Inc. | Implantable obstruction device for septal defects |
US7338514B2 (en) | 2001-06-01 | 2008-03-04 | St. Jude Medical, Cardiology Division, Inc. | Closure devices, related delivery methods and tools, and related methods of use |
WO2002098282A2 (en) | 2001-06-04 | 2002-12-12 | Albert Einstein Healthcare Network | Cardiac stimulating apparatus having a blood clot filter and atrial pacer |
US6585755B2 (en) | 2001-06-29 | 2003-07-01 | Advanced Cardiovascular | Polymeric stent suitable for imaging by MRI and fluoroscopy |
US20030023266A1 (en) * | 2001-07-19 | 2003-01-30 | Borillo Thomas E. | Individually customized atrial appendage implant device |
US7288105B2 (en) * | 2001-08-01 | 2007-10-30 | Ev3 Endovascular, Inc. | Tissue opening occluder |
US6776784B2 (en) | 2001-09-06 | 2004-08-17 | Core Medical, Inc. | Clip apparatus for closing septal defects and methods of use |
US6702835B2 (en) | 2001-09-07 | 2004-03-09 | Core Medical, Inc. | Needle apparatus for closing septal defects and methods for using such apparatus |
US6596013B2 (en) * | 2001-09-20 | 2003-07-22 | Scimed Life Systems, Inc. | Method and apparatus for treating septal defects |
US7318833B2 (en) | 2001-12-19 | 2008-01-15 | Nmt Medical, Inc. | PFO closure device with flexible thrombogenic joint and improved dislodgement resistance |
WO2003053493A2 (en) | 2001-12-19 | 2003-07-03 | Nmt Medical, Inc. | Septal occluder and associated methods |
US20030139819A1 (en) | 2002-01-18 | 2003-07-24 | Beer Nicholas De | Method and apparatus for closing septal defects |
US7048754B2 (en) * | 2002-03-01 | 2006-05-23 | Evalve, Inc. | Suture fasteners and methods of use |
WO2003103476A2 (en) * | 2002-06-05 | 2003-12-18 | Nmt Medical, Inc. | Patent foramen ovale (pfo) closure device with radial and circumferential support |
US7033393B2 (en) * | 2002-06-27 | 2006-04-25 | Raymedica, Inc. | Self-transitioning spinal disc anulus occulsion device and method of use |
WO2004037333A1 (en) | 2002-10-25 | 2004-05-06 | Nmt Medical, Inc. | Expandable sheath tubing |
EP1562653A1 (en) | 2002-11-06 | 2005-08-17 | NMT Medical, Inc. | Medical devices utilizing modified shape memory alloy |
WO2004052213A1 (en) | 2002-12-09 | 2004-06-24 | Nmt Medical, Inc. | Septal closure devices |
US7087072B2 (en) * | 2003-01-22 | 2006-08-08 | Cardia, Inc. | Articulated center post |
US20040234567A1 (en) | 2003-05-22 | 2004-11-25 | Dawson Richard A. | Collapsible shield for smoking animal lure |
JP2007528853A (en) * | 2003-07-08 | 2007-10-18 | テファ, インコーポレイテッド | Poly-4-hydroxybutyrate matrix for sustained release drug delivery |
US7678123B2 (en) * | 2003-07-14 | 2010-03-16 | Nmt Medical, Inc. | Tubular patent foramen ovale (PFO) closure device with catch system |
US8480706B2 (en) * | 2003-07-14 | 2013-07-09 | W.L. Gore & Associates, Inc. | Tubular patent foramen ovale (PFO) closure device with catch system |
WO2005055834A1 (en) | 2003-11-20 | 2005-06-23 | Nmt Medical, Inc. | Device, with electrospun fabric, for a percutaneous transluminal procedure, and methods thereof |
US7361180B2 (en) * | 2004-05-07 | 2008-04-22 | Usgi Medical, Inc. | Apparatus for manipulating and securing tissue |
ATE366547T1 (en) | 2004-02-04 | 2007-08-15 | Carag Ag | IMPLANT FOR OCCLUSION OF A BODY CANAL |
US7871419B2 (en) | 2004-03-03 | 2011-01-18 | Nmt Medical, Inc. | Delivery/recovery system for septal occluder |
US8308760B2 (en) * | 2004-05-06 | 2012-11-13 | W.L. Gore & Associates, Inc. | Delivery systems and methods for PFO closure device with two anchors |
JP2007535997A (en) | 2004-05-07 | 2007-12-13 | エヌエムティー メディカル, インコーポレイティッド | Capturing mechanism of tubular septal occluder |
US7704268B2 (en) | 2004-05-07 | 2010-04-27 | Nmt Medical, Inc. | Closure device with hinges |
WO2006036837A2 (en) * | 2004-09-24 | 2006-04-06 | Nmt Medical, Inc. | Occluder device double securement system for delivery/recovery of such occluder device |
EP1868507A1 (en) | 2005-03-18 | 2007-12-26 | NMT Medical, Inc. | Catch member for pfo occluder |
US8372113B2 (en) * | 2005-03-24 | 2013-02-12 | W.L. Gore & Associates, Inc. | Curved arm intracardiac occluder |
WO2007073566A1 (en) | 2005-12-22 | 2007-06-28 | Nmt Medical, Inc. | Catch members for occluder devices |
-
2002
- 2002-12-19 WO PCT/US2002/040850 patent/WO2003053493A2/en not_active Application Discontinuation
- 2002-12-19 AU AU2002360695A patent/AU2002360695A1/en not_active Abandoned
- 2002-12-19 EP EP02795975A patent/EP1467661A4/en not_active Withdrawn
- 2002-12-19 US US10/326,535 patent/US7867250B2/en not_active Expired - Lifetime
-
2011
- 2011-01-08 US US12/987,111 patent/US20110106149A1/en not_active Abandoned
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6077291A (en) * | 1992-01-21 | 2000-06-20 | Regents Of The University Of Minnesota | Septal defect closure device |
US5810884A (en) * | 1996-09-09 | 1998-09-22 | Beth Israel Deaconess Medical Center | Apparatus and method for closing a vascular perforation after percutaneous puncture of a blood vessel in a living subject |
US5861003A (en) * | 1996-10-23 | 1999-01-19 | The Cleveland Clinic Foundation | Apparatus and method for occluding a defect or aperture within body surface |
US5976174A (en) * | 1997-12-15 | 1999-11-02 | Ruiz; Carlos E. | Medical hole closure device and methods of use |
US5993475A (en) * | 1998-04-22 | 1999-11-30 | Bristol-Myers Squibb Co. | Tissue repair device |
US6113609A (en) * | 1998-05-26 | 2000-09-05 | Scimed Life Systems, Inc. | Implantable tissue fastener and system for treating gastroesophageal reflux disease |
US6206907B1 (en) * | 1999-05-07 | 2001-03-27 | Cardia, Inc. | Occlusion device with stranded wire support arms |
US6379368B1 (en) * | 1999-05-13 | 2002-04-30 | Cardia, Inc. | Occlusion device with non-thrombogenic properties |
US6494888B1 (en) * | 1999-06-22 | 2002-12-17 | Ndo Surgical, Inc. | Tissue reconfiguration |
US6387104B1 (en) * | 1999-11-12 | 2002-05-14 | Scimed Life Systems, Inc. | Method and apparatus for endoscopic repair of the lower esophageal sphincter |
US6214029B1 (en) * | 2000-04-26 | 2001-04-10 | Microvena Corporation | Septal defect occluder |
Non-Patent Citations (1)
Title |
---|
See also references of EP1467661A2 * |
Cited By (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9078630B2 (en) | 2001-06-01 | 2015-07-14 | St. Jude Medical, Cardiology Division, Inc. | Closure devices, related delivery methods and tools, and related methods of use |
US8758403B2 (en) | 2001-12-19 | 2014-06-24 | W.L. Gore & Associates, Inc. | PFO closure device with flexible thrombogenic joint and improved dislodgement resistance |
US9241695B2 (en) | 2002-03-25 | 2016-01-26 | W.L. Gore & Associates, Inc. | Patent foramen ovale (PFO) closure clips |
US9028527B2 (en) | 2002-06-05 | 2015-05-12 | W.L. Gore & Associates, Inc. | Patent foramen ovale (PFO) closure device with radial and circumferential support |
US9017373B2 (en) | 2002-12-09 | 2015-04-28 | W.L. Gore & Associates, Inc. | Septal closure devices |
US8852181B2 (en) | 2003-03-27 | 2014-10-07 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
US8070747B2 (en) | 2003-03-27 | 2011-12-06 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US7922716B2 (en) | 2003-03-27 | 2011-04-12 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
US7972330B2 (en) | 2003-03-27 | 2011-07-05 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US8021362B2 (en) | 2003-03-27 | 2011-09-20 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US8038672B2 (en) | 2003-03-27 | 2011-10-18 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8038669B2 (en) | 2003-03-27 | 2011-10-18 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8038671B2 (en) | 2003-03-27 | 2011-10-18 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8038673B2 (en) | 2003-03-27 | 2011-10-18 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8052678B2 (en) | 2003-03-27 | 2011-11-08 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8066701B2 (en) | 2003-03-27 | 2011-11-29 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
WO2004087235A2 (en) | 2003-03-27 | 2004-10-14 | Cierra, Inc. | Methods and apparatus for treatment of patent foramen ovale |
US8075554B2 (en) | 2003-03-27 | 2011-12-13 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
EP2455037A1 (en) | 2003-03-27 | 2012-05-23 | Terumo Kabushiki Kaisha | Methods and apparatus for treatment of patent foramen ovale |
US7914527B2 (en) | 2003-03-27 | 2011-03-29 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US9861346B2 (en) | 2003-07-14 | 2018-01-09 | W. L. Gore & Associates, Inc. | Patent foramen ovale (PFO) closure device with linearly elongating petals |
US11375988B2 (en) | 2003-07-14 | 2022-07-05 | W. L. Gore & Associates, Inc. | Patent foramen ovale (PFO) closure device with linearly elongating petals |
US9149263B2 (en) | 2003-07-14 | 2015-10-06 | W. L. Gore & Associates, Inc. | Tubular patent foramen ovale (PFO) closure device with catch system |
US9326759B2 (en) | 2003-07-14 | 2016-05-03 | W.L. Gore & Associates, Inc. | Tubular patent foramen ovale (PFO) closure device with catch system |
JP2007504915A (en) * | 2003-09-12 | 2007-03-08 | エヌエムティー メディカル, インコーポレイティッド | PFO closure device with flexible thrombogenic joint and improved detachability |
WO2005027752A1 (en) * | 2003-09-12 | 2005-03-31 | Nmt Medical, Inc. | Pfo closure device with flexible thrombogenic joint and improved dislodgement resistance |
EP1670363A4 (en) * | 2003-09-23 | 2010-11-17 | Cardia Inc | Right retrieval mechanism |
WO2005032335A2 (en) | 2003-09-23 | 2005-04-14 | Cardia, Inc. | Right retrieval mechanism |
EP1670363A2 (en) * | 2003-09-23 | 2006-06-21 | Cardia, Inc. | Right retrieval mechanism |
US8568431B2 (en) | 2004-03-03 | 2013-10-29 | W.L. Gore & Associates, Inc. | Delivery/recovery system for septal occluder |
US8945158B2 (en) | 2004-03-03 | 2015-02-03 | W.L. Gore & Associates, Inc. | Delivery/recovery system for septal occluder |
US8568447B2 (en) | 2004-05-06 | 2013-10-29 | W.L. Gore & Associates, Inc. | Delivery systems and methods for PFO closure device with two anchors |
US8133221B2 (en) | 2004-06-21 | 2012-03-13 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
US8109274B2 (en) | 2005-04-11 | 2012-02-07 | Terumo Kabushiki Kaisha | Methods and electrode apparatus to achieve a closure of a layered tissue defect |
US9084603B2 (en) | 2005-12-22 | 2015-07-21 | W.L. Gore & Associates, Inc. | Catch members for occluder devices |
US9005242B2 (en) | 2007-04-05 | 2015-04-14 | W.L. Gore & Associates, Inc. | Septal closure device with centering mechanism |
US9949728B2 (en) | 2007-04-05 | 2018-04-24 | W.L. Gore & Associates, Inc. | Septal closure device with centering mechanism |
US10485525B2 (en) | 2007-04-05 | 2019-11-26 | W.L. Gore & Associates, Inc. | Septal closure device with centering mechanism |
US10278705B2 (en) | 2008-03-07 | 2019-05-07 | W. L. Gore & Associates, Inc. | Heart occlusion devices |
US9474517B2 (en) | 2008-03-07 | 2016-10-25 | W. L. Gore & Associates, Inc. | Heart occlusion devices |
US10792025B2 (en) | 2009-06-22 | 2020-10-06 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US10806437B2 (en) | 2009-06-22 | 2020-10-20 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US11564672B2 (en) | 2009-06-22 | 2023-01-31 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US11589853B2 (en) | 2009-06-22 | 2023-02-28 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US11596391B2 (en) | 2009-06-22 | 2023-03-07 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US9770232B2 (en) | 2011-08-12 | 2017-09-26 | W. L. Gore & Associates, Inc. | Heart occlusion devices |
US10828019B2 (en) | 2013-01-18 | 2020-11-10 | W.L. Gore & Associates, Inc. | Sealing device and delivery system |
US11771408B2 (en) | 2013-01-18 | 2023-10-03 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US9808230B2 (en) | 2014-06-06 | 2017-11-07 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US10368853B2 (en) | 2014-06-06 | 2019-08-06 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
US11298116B2 (en) | 2014-06-06 | 2022-04-12 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
Also Published As
Publication number | Publication date |
---|---|
EP1467661A4 (en) | 2008-11-05 |
EP1467661A2 (en) | 2004-10-20 |
US7867250B2 (en) | 2011-01-11 |
US20030191495A1 (en) | 2003-10-09 |
WO2003053493A3 (en) | 2003-11-06 |
AU2002360695A1 (en) | 2003-07-09 |
AU2002360695A8 (en) | 2003-07-09 |
US20110106149A1 (en) | 2011-05-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7867250B2 (en) | Septal occluder and associated methods | |
US7318833B2 (en) | PFO closure device with flexible thrombogenic joint and improved dislodgement resistance | |
US8828049B2 (en) | Split ends closure device and methods of use | |
US8308760B2 (en) | Delivery systems and methods for PFO closure device with two anchors | |
US7220265B2 (en) | Patent foramen ovale (PFO) closure method and device | |
JP5486561B2 (en) | Septal defect occluder | |
EP2001368B1 (en) | Screw catch mechanism for pfo occluder | |
US7780700B2 (en) | Patent foramen ovale closure system | |
US20060122646A1 (en) | Daisy design for occlusion device | |
US20130296925A1 (en) | Tubular Patent Foramen Ovale (PFO) Closure Device with Catch System | |
US20090275976A1 (en) | Embolic filtering method and apparatus | |
CA2503666A1 (en) | Septal closure devices | |
US20070166852A1 (en) | Diode-pumped microlasers including resonator microchips and methods for producing the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SK SL TJ TM TN TR TT TZ UA UG UZ VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2002795975 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 2002795975 Country of ref document: EP |
|
NENP | Non-entry into the national phase |
Ref country code: JP |
|
WWW | Wipo information: withdrawn in national office |
Country of ref document: JP |